Best B2B eCommerce Platforms in the USA

Clazar is the leading Enterprise Cloud GTM Platform that helps software companies build, operate, and scale their business across AWS, Azure, and Google cloud marketplaces. From listing to co-selling to revenue reconciliation and recognition, our platform helps companies streamline and automate their entire cloud sales journey from a single, unified platform—with zero operational overhead. Clazar is designed for organizations where cloud marketplaces are a strategic go-to-market channel with executive ownership, revenue targets, and cross-functional accountability. It is built for the controls that enterprise organizations require, with RBAC (role-based access control), SSO (single sign-on), multi-factor authentication, audit logging, zero-trust network security, and robust governance tools that give you complete transparency and control. Our platform integrates seamlessly with leading CRMs like Salesforce and HubSpot and complies fully with industry-leading privacy and security standards such as GDPR, SOC 2, ISO 27017, ISO 27018, and ISO 27701. Teams of any size or skill level can hit the ground running with our intuitive UI, smart automation and built-in guardrails. Our transparent pricing scales with you, with no hidden fees or revenue sharing. Over 300 top companies like Supabase, Zapier, Replit, and Perplexity trust Clazar to power their success on cloud marketplaces.

Manufacturers and wholesalers leverage OneTimePIM to service trade customers with accurate, richly attributed data. Customer-specific channels can expose tailored assortments, contract pricing or technical sheets, delivered via connector, secure API or periodic export. Detailed change logs meet audit requirements common in regulated verticals, while the platform’s powerful spreadsheet view enables rapid bulk updates to large BOM-style catalogues. Integrated DAM ensures high-resolution technical drawings and compliance certificates travel with the SKU, reducing support queries and accelerating partner onboarding.

LogiCommerce, founded in 1999, is the SaaS Headless eCommerce solution for growing and large businesses that offers cutting-edge technology through a fully unified B2B & B2C platform. With over 200 native features, an intuitive BackOffice, real-time integrations with third-party solutions, a globally scalable infrastructure, regular updates and 24/7 support, among many other things, LogiCommerce is one of the most affordable platforms on the market. Thanks to its transparent pricing policy, with no hidden costs or transaction fees, you can reduce technical debt and keep your TCO to a minimum. World renowned brands such as VW, GAP, Audi, eseOese, Munich, Nestlé and IMC Toys use LogiCommerce. 

WizCommerce is an AI commerce platform built for wholesalers, distributors, and manufacturers. It brings together four core products, namely WizOrder — B2B Order Management Platform and Sales Rep Ordering App for Wholesalers and Distributors: Make wholesale ordering effortless with an AI-powered platform featuring deep ERP integration, real-time inventory, and an AI sales copilot for faster, smarter order writing. WizShop — AI-First B2B E-Commerce Platform For Wholesale Teams: Give your buyers a B2B e-commerce software built for wholesale, with customer-specific pricing, personalized assortments, live inventory, and a smooth self-checkout every time. WizStudio — Generate Studio-Quality Product Images with AI: AI-generated catalog images and videos in minutes. Built for brands with 100–10,000+ SKUs. WizPay — Manage Payments as part of the sales workflow: Charge cards, accept ACH, send payment links, and collect invoices directly from orders — without switching tools.

The MarketStudio Suite is a web-based software offering for small, medium and large enterprises, which customers can use to browse, manage, and publish rich product content to Print, Web and Dealer Portals from anywhere/anytime. MarketStudio Suite includes several versatile products and modules that include - Product Information Management (PIM), Online Catalog Portal, Visual Catalog Portal, eCommerce Website, Catalog Automation, PDFxPress Portal and InStudio Plugin Print Publishing using Adobe InDesign. MarketStudio is available both on-premise and on the cloud (subscription) for product manufacturers, distributors and organizations worldwide.

Zoey gives distributors and manufacturers a B2B ecommerce website, self-service buyer portal, order management system, and native mobile sales app in one platform. Zoey becomes the central operating layer between your sales team, buyers, and back-office systems. Built on B2B-specific commerce logic: customer-level pricing, multi-account management, purchase approvals, net terms, and rep ordering on behalf of buyers. No-code storefront, no developers required. Inside sales teams manage quotes and approvals from a web dashboard. Field reps, delivery drivers, and trade show teams capture orders from a mobile app that works offline. Supports barcode scanning and AI ingestion converting PDFs and photos into order drafts. Built-in CRM, order management, quoting, and invoicing, no third-party add-ons. Native integrations: NetSuite, QuickBooks Online, ShipStation. Data mapper connects to any ERP without custom development. Cut manual order entry, scale without hiring.

Kentro redefines ERP for the E-Commerce era, offering a cloud-based, multi-channel solution at a fraction of the cost and complexity of traditional systems like NetSuite or SAP. It's user-friendly, efficient, and packed with essential features: real-time inventory management, order fulfillment, built-in B2B stores, comprehensive supply-chain management, and automated accounting. Plus, seamless integration with 100+ tools and 5000+ zaps ensures that Kentro effortlessly connects and automates your business processes. Capabilities include advanced inventory tracking, dynamic order routing, drop-ship automation, and more, all designed to streamline your E-Commerce operations. Experience the future of ERP with Kentro.

Labra is a powerful platform that revolutionizes the Cloud go-to-market (GTM) process for businesses. It enables zero-engineering marketplace listings, letting companies launch in days—not months. Labra's CRM integration automates co-sell approvals, streamlines channel partner management, and helps scale your success on the Cloud with reduced effort. With AI-powered insights and advanced, real-time analytics, Labra helps teams drive smarter, faster decision-making, giving you a competitive edge. Marketers gain new tools to maximize visibility and impact on cloud marketplaces, while sales teams benefit from reduced manual effort—up to 90%, and a more optimized selling experience. Ultimately, your business gets a new, sustained, scalable revenue channel powered by efficiency, automation, and partnerships.

HubSpot brings your marketing, sales, and service teams together on the same AI-powered customer platform. HubSpot's Customer Platform is not just a tool; it's the heartbeat of your business. Designed with passion and precision, HubSpot's Smart CRM stands out as the ultimate solution for empowering your team to build deeper customer relationships. It transforms the way you engage with your customers by offering a seamlessly integrated, all-in-one platform for sales, marketing, and customer service. With HubSpot's CRM, you gain unparalleled insights into your customer interactions, all organized in an intuitive, easy-to-navigate dashboard that promises to skyrocket your team's efficiency. The platform is engineered to grow with you, offering scalable solutions that adapt to your evolving business needs. What's more, HubSpot's Customer Platform includes a robust free version, packed with essential features, making it the perfect choice for ambitious businesses of all sizes.

SimplyDepo is a mobile-first field sales and retail execution platform for CPG brands, wholesale distributors and merchandising teams. One offline-capable app replaces disconnected tool stacks — spreadsheets, separate order tools, manual QuickBooks reconciliation and WhatsApp threads. Core capabilities: - B2B order management — custom pricing, catalogs, inventory tracking - Retail execution — store audits, shelf compliance, photo capture, task management - Route planning and territory optimization with GPS-verified check-ins - Direct Store Delivery (DSD) — route accounting, van sales, proof of delivery - Offline-first mobile app — auto-syncs when connectivity returns - Native QuickBooks Online integration — orders become invoices automatically - Integrations: Shopify, Stripe, ShipStation, HubSpot, Zapier, open API Teams are live in days. No IT required. No annual contracts.

Pimberly is a powerful cloud-based PIM (Product Information Management) platform that synchronizes all aspects of product data management processes. Pimberly enables businesses to create amazing online experiences with richer, differentiated product descriptions. The platform increases speed to market, facilitates product launches and overseas expansion. Automate all areas of product data processing with intuitive and powerful automation workflows. Gain clear visibility of your product information with defined lifecycles and reporting dashboards. Easily store data in multiple languages and adapt it for various channels and markets. Rapidly onboard new product ranges and publishes to new channels. Do this with automated data import/export functionality. Always release fully optimized products so your customers can find your store. Utilize high-quality product data to improve customer experience and convert more visitors.

The #1 B2B sales platform for medium, large and enterprise consumer goods manufacturers and distributors. Pepperi is a comprehensive, unified commerce platform to manage all aspects of your B2B sales. We combine a B2B eCommerce storefront, sales rep app for mobile order-taking (iOS/Android), Trade Promotions module, Retail Execution, Route Accounting / DSD & Inside Sales - in ONE UNIFIED cloud-based platform that runs online and offline to maximize in-person and online B2B sales. Thanks to its proprietary IPaaS (Integration Platform as a Service), Pepperi syncs seamlessly to your existing tech stack such as ERPs, Accounting software, Payment and Shipping gateways. Pepperi is the ONLY purpose-built mobile solution on the market and currently serves over 1000 companies in 65 countries.

Shopify is a leading all-in-one commerce platform that enables businesses to start, build, and grow their online and physical stores. It offers tools to create customized websites, manage inventory, process payments, and sell across multiple channels including online, in-person, wholesale, and global markets. The platform includes integrated marketing tools, analytics, and customer engagement features to help merchants reach and retain customers. Shopify supports thousands of third-party apps and offers developer-friendly APIs for custom solutions. With world-class checkout technology, Shopify powers over 150 million high-intent shoppers worldwide. Its reliable, scalable infrastructure ensures fast performance and seamless operations at any business size.

Whether you are just starting out or expanding your empire, RepSpark is the leading B2B eCommerce platform built to scale your brand from start to enterprise. With powerful digital tools to measure and grow your sales channel, get started today in scaling your brand. Your D2C eCommerce brand is perfect to start here. Connect your Shopify store instantly to our accelerate platform to showcase your products, create line sheets, catalogs, and more. Now is the time to accelerate. The next level plan for your growing company including robust reporting capabilities, 1-click ERP Integrations, payment solutions, and more. Elevate your brand to the next level with the Professional plan by RepSpark. Fully customizable for the way you scale. Supporting unlimited divisions and brands under one platform. Custom APIs, multi-language capabilities, dashboards & analytics, everything you need to run your enterprise.

Rierino is a next-generation technology developer that leverages low-code/no-code, composable commerce, and embedded intelligence capabilities to allow organizations to rapidly and easily shape their technology. Rierino Commerce platform is a smart headless backend for high-growth commerce designed to support infinite flexibility & scale. With various modules such as product information management (PIM), pricing & promos, search, content (CMS), and journey management, it has a highly extensible structure allowing users to easily add or customize modules through simple configurations. Rierino Core is a smart microservice development platform for digital enterprises targeting the rapid creation of custom solutions. From retail to finance, insurance, telecoms, and government entities, it enables various sectors to accelerate time to innovation across different domains.

JasperX is world-leading leading commerce-first Product Information Management (PIM) platform, built for the era of AI-driven and agentic commerce. As digital commerce shifts from storefronts to algorithms, AI systems increasingly become the first consumers of product information. JasperX helps brands structure, govern, and enrich product data so it can be understood and trusted by AI, agents, marketplaces, retailers, and emerging discovery channels. By centralizing product content, attributes, and digital assets into a single source of truth, JasperX transforms product data into channel-specific outputs optimized for ecommerce and AI-powered experiences. The result is consistent, accurate product information wherever buying decisions happen. Leading brands including Samsonite, Life360/Tile, and Yeti Cycles use JasperX to accelerate operations, with customers reporting workflow improvements of up to 16× and reductions in manual work of up to 80%. Adapt Faster. Grow Smarter.

WooCommerce is a highly customizable, open-source ecommerce platform built on WordPress that empowers businesses to create unique online stores. It supports millions of online shops worldwide, offering flexibility without limits on design or functionality. WooCommerce provides a broad ecosystem of trusted extensions and themes to enhance store features and user experience. The platform integrates seamlessly with payment gateways, marketing tools, and shipping providers. WooCommerce enables merchants to sell products both online and in-person while managing inventory and orders in one place. Its developer-friendly environment allows building tailored ecommerce solutions.

nopCommerce is a robust eCommerce platform for creating an online store of any size and type. nopCommerce offers powerful out-of-the-box features for effective B2C and B2B sales, without any restrictions and absolutely free. nopCommerce allows you to upload an unlimited number of products, manage multiple stores, and create a multi-vendor marketplace. Built-in marketing tools and ready-made integrations with payment and shipping services allow you to quickly launch your successful store. Thanks to the open-source code, you can customize the platform according to your business requirements and integrate it with your corporate CRM or ERP systems.

iPaper is a digital catalog platform that lets you convert your printed leaflets and catalogs into fully interactive digital shopping experiences. Capture shoppers' attention with product images and videos. Drive traffic and sales with in-catalog shopping over email, WhatsApp or directly integrated with your ecommerce webshop. The iPaper platform is built to fit your business and we offer advanced features to fully automate your setup. Getting started with iPaper is much more than just creating a catalog that looks good. It is built to help retailers create an automated interactive marketing channel that will drive traffic and inspire shoppers to buy.

Algolia is a search and discovery API platform for building powerful and composable experiences while solving for relevance with AI and configurable rules. Algolia Search enables our customers to design and implement unique search experiences using the design language of their choice. Algolia Recommend is a robust API that allows you to add “frequently bought together” and “related items” into any digital experience with as little as 6 lines of code.

iM3 SCM Suite is a cloud-based set of tools to Digitally Transform Supply Chain of an Enterprise; automation of Warehouse, Distribution Center & 3PL Operations, multi-Channel Order & eCommerce management. We bring expertise to chose technologies from Mobile Computers Scanners & Barcode Printers, Automated Guided Vehicles (AGV) fully integrated with iM3SCM Suite. API integrations into Shipping (Fedex, UPS, USPS, LTL), fleet manager, Accounting Software Quickbooks Online/Desktop, SAGE etc. Digitally Transform your Asset & Facilities, Repair management, Dealer and Distribution management, Field Service & Fleet Management, Yard Management, Rental Management of Assets, Track Technician, Time & Labor and more. iM3 SCM Suite includes Mobile Apps (phones/tablets) to manage various functions of your operations in-house or on the GO. Choose the best technology for your enterprise to improve productivity, efficiency, quality, improved Invoicing & help reduce cost of operations.

Yodify unifies Distributed Enterprise Catalogs (DEC) with powerful ecommerce and CPQ in one platform. Manage product data once and syndicate it across every channel—dealer, distributor, or direct—ensuring accuracy and consistency everywhere. Integrated ecommerce capabilities support both retail and complex B2B selling, from self-serve purchasing to configurable, quote-driven workflows. With native CPQ, customers can configure products, apply account-specific pricing, and generate quotes instantly, streamlining sales and reducing manual effort. Book a demo and see DEC-powered commerce in action.

Sana Commerce is a ready-to-use commerce platform engineered for B2B. We've paired decades of B2B expertise with smart, integrative software that fits within your existing tech environment, including your ERP, PIM, and CRM. The result? A supportive, personalized, easy buying experience for your customers and streamlined, automated processes for your employees. With Sana Commerce, your business can: Easily bring complex processes online: Enjoy the benefits of B2B-first commerce that knows what you need before you need it. Unburden your team: Automate points of manual intervention to reduce costs and improve efficiency. Drive value faster: Employ a ready-to-use online portal that utilizes your existing business logic. Sana Commerce is a certified SAP and Microsoft Gold partner, backed by a strong global partner network and recognized by leading industry experts.

Orderwerks is a B2B focused Order, Inventory and Fulfillment management platform offering rich features, new technology and integrations to connect your operations together. Customer Ordering, Internal User Ordering, Catalog Management, Order Management, Bulk Management Features, File Uploads, Quotes, and much more. Virtually an unlimited number of ways to customize Orderwerks to perfectly fit your business needs.

UniformMarket is the #1 B2B eCommerce platform for the uniforms industry, trusted by 1,200+ retailers, manufacturers, and distributors since 2005. With over $2B in sales processed, we help businesses across North America, the UK, Australia, and New Zealand manage and grow their uniform sales online. Our solutions include: Uniform Program Management – Run employee uniform programs with advanced tools for allowances, quotas, product access, and reporting. Ideal for managed apparel programs. Wholesale Commerce – Modernize your wholesale operations with portals for B2B buyers, uniform dealers, and group customers. Retail Commerce – Build customizable online stores with features like group stores, custom pricing, and embroidery options. With 500+ configuration options and robust uniform management software, UniformMarket powers scalable, tailored solutions for uniform businesses of all sizes.

WeSupply Labs helps merchants provide the best post-purchase customer experience when selling online with their integrated services designed to assure a smooth post-purchase experience for end-users. Features Summary: ✓Proactive Notifications of delivery status ✓Package Tracking ✓Returns & RMA ✓Store Locator with complete SEO schema and Social Integration ✓In Store Pickup & Curbside for connecting Ecommerce, ERP and POS ✓Delivery Estimate Algorithm based on historical processing & delivery ✓Customer Satisfaction Score survey and Net Promoter Score ✓Analytics & Statistics for data-driven decisions ✓Branded Tracking Page for a premium self-service tracking experience Integrations: 🔗Magento 2 - Full integration from Order Tracking to Returns and Store Pickup 🔗Shopify - Full integration from Order Tracking and Returns 🔗BigCommerce - Full integration from Order Tracking via Zapier App 🔗Netsuite - Full integration via Celigo

BigCommerce is an open ecommerce platform that helps businesses build, customize, launch, and scale online stores across B2C, B2B, international, and multi-storefront commerce. The platform supports storefront design, checkout, payments, inventory, shipping, promotions, product data, analytics, apps, integrations, and developer access. Businesses can launch quickly with visual tools or extend deeper with APIs, custom code, headless commerce, and composable architecture. BigCommerce also supports complex products, regulated selling, subscriptions, hybrid B2B and DTC models, and multiple storefronts from one system. The broader Commerce ecosystem includes Feedonomics for product feed management and Makeswift for visual site building. Built for growing brands, enterprises, developers, and ecommerce teams, BigCommerce helps companies create flexible shopping experiences without forcing them into a one-size-fits-all platform.

CS-Cart Store Builder: Ready-to-Go eCommerce Platform for SMBs and manufacturers. The e-commerce platform that handles 100,000+ products without customization. CS-Cart Store Builder is a professional eCommerce platform to build online stores for SMBs, manufacturers, and wholesale companies. With CS-Cart Store Builder software, you can easily automate the purchasing process and the cooperation with purchasers. No more manual operations! CS-Cart Store Builder enables you to create an unlimited number of categories, import thousands of products in minutes, create product variations, and whatnot. Every product has over 45 parameters to configure, including powerful quantity settings and discounts. CS-Cart Store Builder platform is easy to understand and operate. The admin panel is full of features but it’s well-organized so that you could easily navigate and operate the store. You don’t need programming skills at all to set up your CS-Cart store. And has a free version!

PAYG ecommerce platform that offers every feature to every customer from day one. Create and manage unlimited websites and marketplaces, benefit from the lowest gateway fees, and grow your empire internationally.

Give your customers personalized shopping experience with our AI-powered B2B eCommerce platform - ewiz commerce. No need to wait for months. Get ready to sell eCommerce store and business platform in 30 days. Empower your sales, marketing, and operations with a future-ready platform and grow your business at speed. Built-in AI-powered marketing automation, personalized recommendations, catalog creator, personalized email campaigns, and much more which can boost your growth. 500+ customers across the world $2 bn worth of transactions processed annually Backed by an expert and experienced team of 1700+ people 95% plus customer retention rate 99.99 % website uptime Schedule a free demo today!