Python Agentic AI Tools for Mac

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Browse free open source Python Agentic AI Tools for Mac and projects below. Use the toggles on the left to filter open source Python Agentic AI Tools for Mac by OS, license, language, programming language, and project status.

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  • 1
    AutoGPT

    AutoGPT

    Powerful tool that lets you create and run intelligent agents

    AutoGPT is an experimental open-source application showcasing the capabilities of the GPT-4 language model. This program, driven by GPT-4, chains together LLM "thoughts", to autonomously achieve whatever goal you set. As one of the first examples of GPT-4 running fully autonomously, AutoGPT pushes the boundaries of what is possible with AI.
    Downloads: 25 This Week
    Last Update:
    See Project
  • 2
    OpenHands

    OpenHands

    Open-source autonomous AI software engineer

    Welcome to OpenHands (formerly OpenDevin), an open-source autonomous AI software engineer who is capable of executing complex engineering tasks and collaborating actively with users on software development projects. Use AI to tackle the toil in your backlog, so you can focus on what matters: hard problems, creative challenges, and over-engineering your dotfiles We believe agentic technology is too important to be controlled by a few corporations. So we're building all our agents in the open on GitHub, under the MIT license. Our agents can do anything a human developer can: they write code, run commands, and use the web. We're partnering with AI safety experts like Invariant Labs to balance innovation with security.
    Downloads: 18 This Week
    Last Update:
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  • 3
    OpenManus

    OpenManus

    No fortress, purely open ground. OpenManus is Coming

    OpenManus is an open‑agent AI framework focused on building versatile general-purpose agents capable of autonomously executing complex workflows — such as planning, browsing, tool invocation — all via a pluggable prompts and tools interface. It's being extended with reinforcement learning‑based tuning modules and designed for researchers and developers building custom AI agents.
    Downloads: 18 This Week
    Last Update:
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  • 4
    nanobot

    nanobot

    🐈 nanobot: The Ultra-Lightweight Clawdbot / OpenClaw

    nanobot is an ultra-lightweight personal AI assistant designed to deliver powerful agent capabilities without unnecessary complexity. Built in just ~4,000 lines of clean, readable code, it offers a minimalist alternative to heavyweight agent frameworks while retaining core intelligence and extensibility. nanobot is optimized for speed and efficiency, enabling fast startup times and low resource usage across environments. Its research-ready architecture makes it easy for developers to understand, customize, and extend for experimentation or production use. With simple one-click deployment and a straightforward CLI, users can get a working AI assistant running in minutes. Inspired by Clawdbot but radically simplified, nanobot proves that capable AI agents don’t need massive codebases.
    Downloads: 15 This Week
    Last Update:
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  • 5
    npcpy

    npcpy

    The AI toolkit for the AI developer

    npcpy is a Python-based agent framework and command-line toolkit (the NPC Shell) for developers to build, test, and integrate AI agents into their workflows, including both command-line and GUI interfaces via NPC Studio. Welcome to npcpy, the core library of the NPC Toolkit that supercharges natural language processing pipelines and agent tooling. npcpy is a flexible framework for building state-of-the-art applications and conducting novel research with LLMs. The structure of npcpy also allows one to pass an npc to get_llm_response in addition to using the NPC's wrapped method, allowing you to be flexible in your implementation and testing.
    Downloads: 14 This Week
    Last Update:
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  • 6
    IntentKit

    IntentKit

    An open and fair framework for everyone to build AI agents

    IntentKit is a natural language understanding (NLU) library focused on intent recognition and entity extraction, enabling developers to build conversational AI applications.
    Downloads: 13 This Week
    Last Update:
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  • 7
    OpenAdapt

    OpenAdapt

    Open Source Generative Process Automation

    OpenAdapt is the open source software adapter between Large Multimodal Models (LMMs) and traditional desktop and web Graphical User Interfaces (GUIs). OpenAdapt learns to automate your desktop and web workflows by observing your demonstrations. Spend less time on repetitive tasks and more on work that truly matters. Boost team productivity in HR operations. Automate candidate sourcing using LinkedIn Recruiter, LinkedIn Talent Solutions, GetProspect, Reply.io, outreach.io, Gmail/Outlook, and more. Streamline legal procedures and case management. Automate tasks like generating legal documents, managing contracts, tracking cases, and conducting legal research with LexisNexis, Westlaw, Adobe Acrobat, Microsoft Excel, and more.
    Downloads: 13 This Week
    Last Update:
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  • 8
    SafeClaw

    SafeClaw

    Chat with it via text and voice

    SafeClaw is an open-source, entirely local alternative to cloud-based AI assistants like OpenClaw, enabling users to build a personal assistant that runs on their own machine without incurring API usage charges or exposing data to third-party services. It emphasizes privacy and predictability by using traditional programming, rule-based intent parsing, and established machine learning tools rather than large language models, meaning there are no per-token API costs and deterministic behavior. The assistant offers features such as voice control using fully local speech-to-text (Whisper) and text-to-speech (Piper) capabilities, news aggregation with extractive summarization, and smart home or Bluetooth device control. SafeClaw supports multiple channels, including CLI and Telegram, and avoids prompt injection risk because it doesn’t rely on LLMs for core operations.
    Downloads: 13 This Week
    Last Update:
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  • 9
    Trail of Bits Skills Marketplace

    Trail of Bits Skills Marketplace

    Trail of Bits Claude Code skills for security research, vulnerability

    Trail of Bits Skills Marketplace is a specialized Claude Code skills marketplace built by the security research firm Trail of Bits that focuses on enhancing AI-assisted workflows for vulnerability discovery, testing, and secure development. The repository groups a set of plug-in skills tailored toward static analysis, code auditing, secure defaults detection, and other practices that matter in software security. Users can easily add the marketplace to a Claude Code environment, browse available plugins, and install specific skills for tasks like automatic Semgrep rule creation, entry-point analysis in smart contracts, or insecure defaults detection. This project leverages the agent skills architecture to let AI assistants take on detailed, repeatable security procedures that are typically manual, such as parsing Burp Suite projects or conducting variant analysis across codebases.
    Downloads: 12 This Week
    Last Update:
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  • 10
    Klavis AI

    Klavis AI

    MCP integration platforms for AI agents to use tools at any scale

    Klavis AI is a Y Combinator X25-backed open-source infrastructure platform that enables AI agents to reliably connect with external tools and services at scale through Model Context Protocol (MCP). Founded by ex-Google DeepMind and ex-Lyft engineers, Klavis provides 50+ production-ready MCP servers with enterprise OAuth support for GitHub, Slack, Gmail, Salesforce, Linear, Notion, and more. The flagship product Strata solves tool overload through progressive discovery, achieving +13% higher accuracy and 83%+ success on complex workflows. Developers can integrate via Python/TypeScript SDKs or REST API, with support for OpenAI, Claude, Gemini, LangChain, LlamaIndex, and CrewAI. Features include built-in authentication, multi-tenancy, hosted servers, Docker support, and enterprise security guardrails. Licensed under Apache 2.0, Klavis simplifies AI development by eliminating complex authentication management and enabling seamless workflow automation across multiple applications.
    Downloads: 10 This Week
    Last Update:
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  • 11
    OpenAI Python

    OpenAI Python

    The official Python library for the OpenAI API

    The OpenAI Python library provides convenient access to the OpenAI REST API from any Python 3.7+ application. The library includes type definitions for all request params and response fields, and offers both synchronous and asynchronous clients powered by httpx.
    Downloads: 10 This Week
    Last Update:
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  • 12
    Skyvern

    Skyvern

    Automate browser-based workflows with LLMs and Computer Vision

    Skyvern uses a combination of computer vision and AI to understand content on a webpage, making it adaptable to any website. Skyvern takes instructions in natural language, allowing it to execute complex objectives with simple commands. Skyvern is an API-first product. Workflows execute in the cloud, allowing it to run hundreds of workflows at the same time. Skyvern's AI decisions come with built-in explanations, providing clear summaries and justifications for every action. Support for proxies, with support for country, state, or even precise zip-code level targeting. Skyvern understands how to solve CAPTCHAs to complete complicated workflows. Support for authenticating into user accounts, including support for 2FA/TOTP. Extract data from workflows in any schema of your choice including CSV or JSON. Automate procurement pipelines, breeze through government forms, and complete workflows in any language.
    Downloads: 10 This Week
    Last Update:
    See Project
  • 13
    Agent Development Kit (ADK)

    Agent Development Kit (ADK)

    Open-source, code-first Python toolkit for building, evaluating, etc.

    ADK (Android Device Key) Python is a reference implementation by Google for working with Android attestation keys in Python. It facilitates the integration of Android attestation features into backends or systems that require verification of device identity and integrity. This is especially important in high-security applications where verifying that a device is genuine and uncompromised is critical. ADK Python helps developers verify hardware-backed keys, work with JSON Web Tokens (JWT), and integrate with Android’s Key Attestation infrastructure.
    Downloads: 9 This Week
    Last Update:
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  • 14
    ChemCrow

    ChemCrow

    Chemcrow

    ChemCrow is an AI-powered framework designed to assist in chemical research and discovery. It integrates AI models with chemical knowledge bases to provide intelligent recommendations for synthesis planning, reaction prediction, and material discovery. This tool helps automate and accelerate research in computational chemistry and drug development.
    Downloads: 9 This Week
    Last Update:
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  • 15
    Claude Skills

    Claude Skills

    Public repository for Agent Skills

    Claude Skills is a public repository that showcases and serves as a collection of skills — modular, reusable packages of instructions, scripts, and resources that Claude and other compatible agents can dynamically discover and load to extend their capabilities on specialized tasks. Rather than relying on handcrafted prompts every time, Skills teach an AI agent procedural knowledge and task-specific workflows so it can apply that expertise reliably, whether the task involves document creation, data analysis, design generation, or technical automation. Each Skill lives in its own directory with a SKILL.md file containing metadata and instructions, and can include supplemental scripts or assets that the agent uses to perform complex operations when relevant.
    Downloads: 8 This Week
    Last Update:
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  • 16
    AskUI Vision Agent

    AskUI Vision Agent

    Enable AI to control your desktop, mobile and HMI devices

    AskUI’s Vision Agent is an automation framework that allows you—and AI agents—to control real desktops, mobile devices, and HMI systems by perceiving the UI and performing actions like clicking, typing, scrolling, and drag-and-drop. It is designed for multi-platform compatibility and supports multiple AI models so you can tailor perception and decision-making to your workload. The repository presents a feature overview, sample media, and frequent release notes, which show ongoing improvements such as CORS checks and other operational tweaks. The broader AskUI documentation covers the Python Vision Agent along with suite services and inference APIs, indicating a productized ecosystem rather than a single library. Community-curated lists also recognize Vision Agent as part of the broader “GUI agents” landscape, placing it among other computer-use agents.
    Downloads: 7 This Week
    Last Update:
    See Project
  • 17
    Android Use

    Android Use

    Automate native Android apps with AI using accessibility APIs

    android-action-kernel is an open source Python library designed to let AI agents control and automate native Android applications running on real devices or emulators. It fills a gap in automation tooling by focusing on mobile-first workflows where traditional browser or desktop-based automation doesn’t work; such as logistics, gig work, field operations, and other industries reliant on phones or tablets. The project works by using Android’s accessibility API to extract structured UI state (as XML) from the device, which is then fed to a large language model (LLM) like OpenAI’s models for decision-making, and actions are executed via the Android Debug Bridge (ADB). This approach bypasses expensive vision-based models and provides faster, cheaper automation with fine-grained interaction capabilities (for example, tapping buttons, typing text, navigating screens).
    Downloads: 6 This Week
    Last Update:
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  • 18
    CAMEL AI

    CAMEL AI

    Finding the Scaling Law of Agents. A multi-agent framework

    The rapid advancement of conversational and chat-based language models has led to remarkable progress in complex task-solving. However, their success heavily relies on human input to guide the conversation, which can be challenging and time-consuming. This paper explores the potential of building scalable techniques to facilitate autonomous cooperation among communicative agents and provide insight into their "cognitive" processes. To address the challenges of achieving autonomous cooperation, we propose a novel communicative agent framework named role-playing. Our approach involves using inception prompting to guide chat agents toward task completion while maintaining consistency with human intentions. We showcase how role-playing can be used to generate conversational data for studying the behaviors and capabilities of chat agents, providing a valuable resource for investigating conversational language models.
    Downloads: 6 This Week
    Last Update:
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  • 19
    Open Autonomy

    Open Autonomy

    A framework for the creation of autonomous agent services

    Open Autonomy is a framework that enables the development of autonomous economic agents (AEAs) capable of operating independently in various economic contexts.
    Downloads: 6 This Week
    Last Update:
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  • 20
    OpenAI Agent Skills

    OpenAI Agent Skills

    Skills Catalog for Codex

    OpenAI Agent Skills is an open-source repository that serves as a broad catalog of agent skills designed to extend the capabilities of OpenAI Codex and other AI coding agents. It organizes reusable, task-specific workflows, instructions, scripts, and resources into modular skill folders so that an AI agent can reliably perform complex tasks without repeated custom prompting, making agent behavior more predictable and composable. Each skill is defined with clear metadata and instructions organizing how an AI assistant should complete specific tasks ranging from project management to code generation and documentation assistance. The repository supports community contributions, allowing developers to add new skills or update existing ones to keep the catalog relevant and practical for evolving use cases.
    Downloads: 6 This Week
    Last Update:
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  • 21
    gpt-engineer

    gpt-engineer

    Full stack AI software engineer

    gpt-engineer is an open-source platform designed to help developers automate the software development process using natural language. The platform allows users to specify software requirements in plain language, and the AI generates and executes the corresponding code. It can also handle improvements and iterative development, giving users more control over the software they’re building. Built with a terminal-based interface, gpt-engineer is customizable, enabling developers to experiment with AI-assisted programming and refine their development process. It is especially useful for automating the coding and iterative feedback loop in software development.
    Downloads: 6 This Week
    Last Update:
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  • 22
    Airweave

    Airweave

    Airweave lets agents search any app

    Airweave is an open-source platform that enables agents to semantically search across various applications, databases, and APIs. By transforming disparate data sources into a unified, searchable knowledge base, Airweave facilitates intelligent information retrieval through REST APIs or the MCP protocol. It's particularly useful for building AI agents that require access to structured and unstructured data across multiple platforms.
    Downloads: 5 This Week
    Last Update:
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  • 23
    Browser Use

    Browser Use

    Make websites accessible for AI agents

    Browser-Use is a framework that makes websites accessible for AI agents, enabling automated interactions and data extraction from web pages.
    Downloads: 5 This Week
    Last Update:
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  • 24
    LangGraph

    LangGraph

    Build resilient language agents as graphs

    LangGraph is a library for building stateful, multi-actor applications with LLMs, used to create agent and multi-agent workflows. Compared to other LLM frameworks, it offers these core benefits: cycles, controllability, and persistence. LangGraph allows you to define flows that involve cycles, essential for most agentic architectures, differentiating it from DAG-based solutions. As a very low-level framework, it provides fine-grained control over both the flow and state of your application, crucial for creating reliable agents. Additionally, LangGraph includes built-in persistence, enabling advanced human-in-the-loop and memory features.
    Downloads: 5 This Week
    Last Update:
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  • 25
    Softaworks Agent Skills

    Softaworks Agent Skills

    A curated collection of skills for AI coding agents

    The Softaworks Agent Toolkit is a comprehensive collection of agent skills, commands, and sub-agents designed to augment AI coding assistants like Claude Code, Codex, and Cursor with practical workflow capabilities. It packages broad categories of modular skills that help with development automation, documentation creation, planning, architecture, testing, and soft professional workflows. Beyond simple skills, it also includes agents and CLI slash commands that help developers automate common tasks such as pattern finding, diagram generation, requirement drafting, and daily standup preparation. The toolkit’s modular design follows the Agent Skills format, making it easy for users to install only what’s needed via CLI installers or plugin marketplaces. Because the set spans from low-level utilities like dependency updaters to higher-level planning and communication aids, it can streamline many aspects of a developer’s day-to-day work.
    Downloads: 5 This Week
    Last Update:
    See Project
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