HIV-specific T-cell Responses and Generalized Activation in HIV-1 Infected Long-term Non-progressors and Progressors from South India (Q90446339)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30543175%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

title

HIV-specific T-cell Responses and Generalized Activation in HIV-1 Infected Long-term Non-progressors and Progressors from South India (English)

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14 April 2020

3

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author name string

Chinnambedu Ravichandran Swathirajan

1

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14 April 2020

Ramachandran Vignesh

2

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14 April 2020

Uma Shanmugasundaram

4

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14 April 2020

Pannerselvam Nandagopal

5

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14 April 2020

Sunil Suhas Solomon

6

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14 April 2020

Amrose Pradeep

7

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14 April 2020

Shanmugam Saravanan

8

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14 April 2020

Kailapuri Gangatharan Murugavel

9

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publication date

1 January 2018

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14 April 2020

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volume

16

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issue

4

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page(s)

302-314

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Creative Commons Attribution 4.0 International

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copyright license

start time

14 January 2019

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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12 December 2020

Production of beta-chemokines in human immunodeficiency virus (HIV) infection: evidence that high levels of macrophage inflammatory protein-1beta are associated with a decreased risk of HIV disease progression

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Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy.

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12 December 2020

Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.

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12 December 2020

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12 December 2020

Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy

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12 December 2020

T(H)1 to T(H)2 shift of cytokines in peripheral blood of HIV-infected patients is detectable by reverse transcriptase polymerase chain reaction but not by enzyme-linked immunosorbent assay under nonstimulated conditions.

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12 December 2020

Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors

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https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

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https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Antigen-specific production of RANTES, macrophage inflammatory protein (MIP)-1alpha, and MIP-1beta in vitro is a correlate of reduced human immunodeficiency virus burden in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Higher macrophage inflammatory protein (MIP)-1alpha and MIP-1beta levels from CD8+ T cells are associated with asymptomatic HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Simian immunodeficiency virus replicates to high levels in naturally infected African green monkeys without inducing immunologic or neurologic disease

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https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Skewed maturation of memory HIV-specific CD8 T lymphocytes

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12 December 2020

RANTES production from CD4+ lymphocytes correlates with host genotype and rates of human immunodeficiency virus type 1 disease progression

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https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Decay kinetics of human immunodeficiency virus-specific CD8+ T cells in peripheral blood after initiation of highly active antiretroviral therapy

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12 December 2020

Positive association between beta-chemokine-producing T cells and HIV type 1 viral load in HIV-infected subjects in Abidjan, Côte d'Ivoire

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https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Persistent numbers of tetramer+ CD8(+) T cells, but loss of interferon-gamma+ HIV-specific T cells during progression to AIDS

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https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Naturally HIV-1 seroconverters with lowest viral load have best prognosis, but in time lose control of viraemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Presence of HIV-1 Gag-specific IFN-gamma+IL-2+ and CD28+IL-2+ CD4 T cell responses is associated with nonprogression in HIV-1 infection

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https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions

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https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Decreased expression of activation markers on CD4 T lymphocytes of HIV-infected long-term non-progressors

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https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Phenotype and functional characteristics of HIV-specific cytotoxic CD8+ T cells in chronically infected patients: dual effects of highly active antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Differences in disease progression in a cohort of long-term non-progressors after more than 16 years of HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Kinetics of virus-specific CD8+ T cells and the control of human immunodeficiency virus infection

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https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Immunopathogenesis of HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Advances in understanding immunologic control of HIV infection

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https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Reduced CD4 T cell activation and in vitro susceptibility to HIV-1 infection in exposed uninfected Central Africans

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Low immune activation despite high levels of pathogenic human immunodeficiency virus type 1 results in long-term asymptomatic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Prognostic value of HIV-1 RNA, CD4 cell count, and CD4 Cell count slope for progression to AIDS and death in untreated HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Functional characterization of BK virus-specific CD4+ T cells with cytotoxic potential in seropositive adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

T-cell quality in memory and protection: implications for vaccine design

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

No major differences in the functional profile of HIV Gag and Nef-specific CD8+ responses between long-term nonprogressors and typical progressors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

HIV pathogenesis: 25 years of progress and persistent challenges

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Early Control of HIV-1 Infection in Long-Term Nonprogressors Followed Since Diagnosis in the ANRS SEROCO/HEMOCO Cohort

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

CTL quality and the control of human retroviral infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Clinical outcomes of elite controllers, viremic controllers, and long-term nonprogressors in the US Department of Defense HIV natural history study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Specific phenotypic and functional features of natural killer cells from HIV-infected long-term nonprogressors and HIV controllers

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Cytotoxic granule release dominates gag-specific CD4+ T-cell response in different phases of HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

HIV+ elite controllers have low HIV-specific T-cell activation yet maintain strong, polyfunctional T-cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Long-term nonprogressive disease among untreated HIV-infected individuals: clinical implications of understanding immune control of HIV.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Human immunodeficiency virus type 1 long-term non-progressors: the viral, genetic and immunological basis for disease non-progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Mechanisms of HIV-associated lymphocyte apoptosis: 2010

1 reference

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12 December 2020

Epidemiology and clinical characteristics of elite controllers

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

T cell Activation does not drive CD4 decline in longitudinally followed HIV-infected Elite Controllers

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Immunogenic and tolerogenic signatures in human immunodeficiency virus (HIV)-infected controllers compared with progressors and a conversion strategy of virus control

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Thirty Years with HIV Infection-Nonprogression Is Still Puzzling: Lessons to Be Learned from Controllers and Long-Term Nonprogressors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

High-dimensional immunomonitoring models of HIV-1-specific CD8 T-cell responses accurately identify subjects achieving spontaneous viral control

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

CD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Immune responses during spontaneous control of HIV and AIDS: what is the hope for a cure?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Early skewed distribution of total and HIV-specific CD8+ T-cell memory phenotypes during primary HIV infection is related to reduced antiviral activity and faster disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

Targeting TNF and TNF Receptor Pathway in HIV-1 Infection: from Immune Activation to Viral Reservoirs

1 reference

https://pubmed.ncbi.nlm.nih.gov/30543175

12 December 2020

10.2174/1570162X17666181212122607

Identifiers

DOI

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14 April 2020

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14 April 2020

PubMed publication ID

30543175

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