Implications of Immune Checkpoint Expression During Aging in HIV-Infected People on Antiretroviral Therapy (Q90444562)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31578868%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

title

Implications of Immune Checkpoint Expression During Aging in HIV-Infected People on Antiretroviral Therapy (English)

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14 April 2020

3

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14 April 2020

author name string

Lesley R de Armas

1

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14 April 2020

Suresh Pallikkuth

2

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14 April 2020

Rajendra Pahwa

4

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14 April 2020

Savita Pahwa

5

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14 April 2020

publication date

1 November 2019

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AIDS Research and Human Retroviruses

14 April 2020

published in

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14 April 2020

volume

35

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issue

11-12

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page(s)

1112-1122

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Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.

14 April 2020

cites work

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Viral immune evasion due to persistence of activated T cells without effector function

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Large clonal expansions of human virus-specific memory cytotoxic T lymphocytes within the CD57+ CD28- CD8+ T-cell population

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Potential predictive factors of osteoporosis in HIV-positive subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

HIV and bone mineral density

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Episomal Viral cDNAs Identify a Reservoir That Fuels Viral Rebound after Treatment Interruption and That Contributes to Treatment Failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Anti-TIM3 antibody promotes T cell IFN-γ-mediated antitumor immunity and suppresses established tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Survival and proliferation of CD28- T cells during HIV-1 infection relate to the amplitude of viral replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009 H1N1/09 vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Inflammation, Immune Activation, and CVD Risk in Individuals With HIV Infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Immune activation in HIV-infected aging women on antiretrovirals--implications for age-associated comorbidities: a cross-sectional pilot study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Nivolumab plus ipilimumab in advanced melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Incidence and timing of cancer in HIV-infected individuals following initiation of combination antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Three distinct phases of HIV-1 RNA decay in treatment-naive patients receiving raltegravir-based antiretroviral therapy: ACTG A5248

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Age, comorbidities, and AIDS predict a frailty phenotype in men who have sex with men

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Programmed death-1 expression on CD4⁺ and CD8⁺ T cells in treated and untreated HIV disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

HIV infection Worsens Age-Associated Defects in Antibody Responses to Influenza Vaccine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Elevation of Tim-3 and PD-1 expression on T cells appears early in HIV infection, and differential Tim-3 and PD-1 expression patterns can be induced by common γ -chain cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

HIV-1 Infection Accelerates Age According to the Epigenetic Clock

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Immunological biomarkers predict HIV-1 viral rebound after treatment interruption

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Assessing immune aging in HIV-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Total HIV-1 DNA, a Marker of Viral Reservoir Dynamics with Clinical Implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Functional exhaustion of CD4+ T cells induced by co-stimulatory signals from myeloid leukaemia cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Dances with cytokines, featuring TFH cells, IL-21, IL-4 and B cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Induction of IL21 in Peripheral T Follicular Helper Cells Is an Indicator of Influenza Vaccine Response in a Previously Vaccinated HIV-Infected Pediatric Cohort.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Cancer immunotherapies targeting the PD-1 signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Cancer risk in HIV-infected people in the USA from 1996 to 2012: a population-based, registry-linkage study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Reevaluation of immune activation in the era of cART and an aging HIV-infected population

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Impact of aging and HIV infection on serologic response to seasonal influenza vaccination

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Measuring replication competent HIV-1: advances and challenges in defining the latent reservoir

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Expression of PD-1 and Tim-3 markers of T-cell exhaustion is associated with CD4 dynamics during the course of untreated and treated HIV infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Total HIV DNA: a global marker of HIV persistence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31578868

12 December 2020

Identifiers

DOI

10.1089/AID.2019.0135

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31578868%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

1 reference