Potent antiviral synergy between monoclonal antibody and small-molecule CCR5 inhibitors of human immunodeficiency virus type 1 (Q24673555)

2

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Daniel C Pevear

3

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Paul J Maddon

4

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William C Olson

Antimicrobial Agents and Chemotherapy

5

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language of work or name

English

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publication date

October 2006

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published in

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volume

50

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issue

10

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page(s)

3289-96

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cites work

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Two-Drug Combinations of Zidovudine, Didanosine, and Recombinant Interferon- A Inhibit Replication of Zidovudine-Resistant Human Immunodeficiency Virus Type 1 Synergistically In Vitro

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HIV-1 coreceptors and their inhibitors

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Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity

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Analysis of binding sites for the new small-molecule CCR5 antagonist TAK-220 on human CCR5.

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Antiviral activity and safety of 873140, a novel CCR5 antagonist, during short-term monotherapy in HIV-infected adults

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28 September 2017

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A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Anti-human immunodeficiency virus interactions of SCH-C (SCH 351125), a CCR5 antagonist, with other antiretroviral agents in vitro

28 September 2017

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Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5.

28 September 2017

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28 September 2017

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28 September 2017

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Candidate microbicides block HIV-1 infection of human immature Langerhans cells within epithelial tissue explants

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28 September 2017

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Polymorphism in RANTES chemokine promoter affects HIV-1 disease progression

28 September 2017

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Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5

28 September 2017

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Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function

28 September 2017

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The thiocarboxanilide nonnucleoside inhibitor UC781 restores antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus type 1.

28 September 2017

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Human immunodeficiency virus type 1 membrane fusion mediated by a laboratory-adapted strain and a primary isolate analyzed by resonance energy transfer.

28 September 2017

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Applications of standard error estimates in unrestricted factor analysis: significance tests for factor loadings and correlations

28 September 2017

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HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain

28 September 2017

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An anti-CCR5 monoclonal antibody and small molecule CCR5 antagonists synergize by inhibiting different stages of human immunodeficiency virus type 1 entry

28 September 2017

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Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1.

28 November 2018

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TAK-652, a novel CCR5 inhibitor, has favourable drug interactions with other antiretrovirals in vitro

28 November 2018

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PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression and Characterization of CD4-IgG2, a Novel Heterotetramer That Neutralizes Primary HIV Type 1 Isolates

1 reference

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