Best USB Security Software

Compare the Top USB Security Software as of October 2026

What is USB Security Software?

USB security software is a type of application designed to protect against malicious USB attacks. It can help keep your data safe by monitoring your USB ports for any unauthorized activity and preventing the transfer of any potentially dangerous files from unsecured flash drives. This software comes with various levels of protection, such as encryption, anti-malware scans, and real-time alerts. In addition, it can also provide you with an audit trail that tracks all activities associated with your USB ports. Lastly, these applications are simple to install and use yet can be highly effective in keeping your data secure against malicious attacks. Compare and read user reviews of the best USB Security software currently available using the table below. This list is updated regularly.

  • 1
    ThreatLocker

    ThreatLocker

    ThreatLocker

    ThreatLocker is a Zero Trust Platform that prevents cyber threats by blocking unknown applications, enforcing least privilege, and controlling what can run across your environment. Using Allowlisting, Ringfencing, Network Control, and more, ThreatLocker stops ransomware, zero-day attacks, and unauthorized activity before execution, rather than relying on detection after the fact. Built for modern IT and cybersecurity teams, the platform delivers centralized visibility and policy management across endpoints, users, and applications. ThreatLocker reduces attack surface, limits lateral movement, and supports compliance with detailed audit logs. With fast deployment, a large built-in application library, and streamlined approvals, organizations can strengthen security while minimizing operational overhead and maintaining business continuity.
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  • 2
    Safetica

    Safetica

    Safetica

    Safetica delivers Intelligent Data Security. Its AI-powered platform helps security teams see and control how sensitive data is used across endpoints, cloud applications, and AI, so they can prevent data loss, reduce insider risk, and support compliance without disrupting productive work. Safetica AI Protection gives teams visibility into AI activity and sensitive data sharing, with controls that protect data while enabling productive AI use. ✔️ Data Protection: Classify, monitor, and control sensitive data across endpoints, cloud applications, and AI interactions in real time. ✔️ Insider Risk and User Behavior: Identify risky and anomalous activity to reduce the risk of careless data handling, compromised accounts, and malicious actions. ✔️ Compliance and Data Discovery: Discover and classify sensitive data, then use audit-ready reporting to support compliance across data at rest, in motion, and in use. ✔️ Cloud Security: Protect sensitive data across Microsoft 365 and other cloud and file-sharing platforms by monitoring and classifying files and enforcing policies on file activity.
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    Starting Price: $72/user
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  • 3
    eAuditor Cloud

    eAuditor Cloud

    BTC Sp. z o.o.

    eAuditor Cloud is a comprehensive SaaS platform for IT asset management, monitoring, security, and data protection. With more than 20 years of experience in corporate and public sector environments, it combines proven functionality with the accessibility and scalability of the cloud. The system provides full visibility and control over the infrastructure - from automatic inventory of computers, servers, operating systems, and software to continuous monitoring of users, devices, and network activity. Advanced modules include remote management, patch installation, BitLocker encryption, SOC dashboard, and task automation. A professional DLP engine protects sensitive data in use, at rest, and in transit through classification, rules, and policies. AI support for CMD/PowerShell and ChatGPT integration help administrators save time and eliminate repetitive tasks. eAuditor Cloud grows with your business - from a free version for up to 100 devices to advanced enterprise-grade packages.
    Starting Price: 0,4 € / mo./ per 1 PC
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    Donglify

    Donglify

    Donglify

    Donglify solves the dongle-sharing problem. The app allows you to use a USB dongle even when you don't have it at hand. You can redirect your licensed USB dongles to any location over the network. It’s not uncommon that an owner of a licensed USB key needs to access the functionality of their device when a physical connection to the device is not possible. Donglify helps resolve this problem once and for all. Thanks to the advanced port redirection technology that powers the solution, you can forward your USB security dongles over any distance and to any environment. If a USB dongle that’s attached to your computer is not recognized by the virtual machine you are running, no worries. Just install Donglify on both the host and guest operating systems and redirect your device to a virtual environment without any limitations. Create login tokens and send them to other Donglify users.
    Starting Price: $16 per month
  • 5
    Endpoint Protector
    Endpoint Protector is an advanced, all-in-one Data Loss Prevention solution for Windows, macOS and Linux, that puts an end to data leaks and data theft and offers seamless control of portable storage devices. Endpoint Protector’s filtering capabilities for data at rest and in motion range from file type to predefined content based on dictionaries, regular expressions or data protection regulations such as GDPR, PCI DSS, CCPA, HIPAA, etc. Endpoint Protector features several specialized modules that can be mixed and matched based on client needs. The modules comprise: Content Aware Protection, Device Control, Enforced Encryption, and eDiscovery . It makes work more convenient, secure and enjoyable, offering an excellent ROI.
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    AccessPatrol

    AccessPatrol

    CurrentWare Inc.

    AccessPatrol is a data loss prevention and USB device control software that provides a proactive solution for preventing data breaches caused by illicit data transfers. AccessPatrol controls a variety of peripherals, including… - Storage devices such as USB flash drives and external hard drives - Wireless Devices such as Bluetooth, Infrared, and WiFi - Communication Ports such as Serial and Parallel ports - Imaging Devices such as Scanners or Cameras, and… - Other Devices such as network share drives, printers, and mobile phones File operations alerts and permissions can be configured to alert IT administrators to suspicious file operations and proactively prevent data transfers to unauthorized users. The security policies are enforced by a software agent that is installed on your user’s computers. This keeps devices restricted and monitored even when the computers are taken off of the network.
    Starting Price: $6 PUPM
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    BUFFERZONE

    BUFFERZONE

    Bufferzone Security

    BUFFERZONE provides a patented containment and disarming solution that defends endpoints against advanced malware and zero-day attacks while maximizing user and IT productivity. By isolating potentially malicious content coming from browsers, email and removable media, BUFFERZONE defends individuals and organizations from advanced threats that evade detection. BUFFERZONE disarms content for securely transferring it from the container to the native endpoint and secure network zones, and provides critical intelligence for enterprise-wide security analytics. Easy to deploy and configure, BUFFERZONE is a lightweight solution that provides cost-effective containment for up to thousands of endpoints.
  • 8
    ManageEngine Device Control Plus
    Device Control Plus is an enterprise software, specially designed for complete device control and file access management. It is equipped with an intuitive interface using which the admin can efficiently classify USB and other peripheral devices as trusted, blocked or allowed temporary access. It is also equipped with numerous data security capabilities including assigning read-only file access, restricting file copying or blocking unauthorized file transfers. Additionally for extensive visibility over device actions and forensic analysis of policy efficacy and network performance, file tracing and file shadowing reports will be automatically generated. Know who is using what device on which endpoint with clear-cut audit data and reports, and receive instant alerts in case of unauthorized access.
    Starting Price: $5.95 per user per year
  • 9
    Gilisoft #1 All-in-One Toolkit Suite
    22 Powerful and Useful Software in One Pack, which including Video Converter, Video Editor, Screen Recorder Pro, Slideshow Movie Creator, Movie DVD Converter, Movie DVD Copy, Movie DVD Creator, Audio Converter Ripper, Audio Recorder Pro, Audio Editor, MP3 CD Maker, File Lock Pro, USB Encryption, Secure Disc Creator, Full Disk Encryption, Private Disk, USB Lock, and RAM Disk, Image Watermark Remover, Video Watermark Remover, Formathor, Data Recovery. #1 All-in-One Toolkit Suite is able to do almost every multimedia ripping, converting, burning, and editing imaginable. You can make your PC perfectly safe with encryption tools, get back lost files and also speed up your PC performance with RAMDisk. In conclusion, you can do almost multimedia work with audio and video tools, and you can do encryption operation with encryption software. Just free download and experience it now!
    Starting Price: $149.99
  • 10
    DriveLock

    DriveLock

    DriveLock

    Cyber threats are everywhere, but protecting your IT systems should be as natural as locking your front door. With DriveLock’s HYPERSECURE Platform, safeguarding your endpoints and business data is easier than ever. We integrate the latest security technologies and share our expertise, so you can focus on what matters—without worrying about data protection. Zero Trust Platform takes a proactive approach, eliminating security gaps before they become a risk. By enforcing centralized policies, DriveLock ensures employees and endpoints access only what they need—following the golden rule of cybersecurity: ''never trust, always verify''.
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    Acronis DeviceLock DLP
    Acronis DeviceLock DLP provides comprehensive endpoint DLP (endpoint data loss prevention) – discovering and protecting sensitive data while monitoring the operations involving that information. Prevent data leakage due to employee negligence or malicious insiders by blocking any unauthorized attempt to access or transfer data, discovering and protecting sensitive data-at-rest. Reduce the complexity of data protection and cut reporting times with a single DLP solution for thorough visibility over data flows and user behavior. Reduce information security risks and comply with IT security standards and regulations by enforcing data use and handling policies that users can’t avoid following. Save the time and hassle associated with managing a DLP solution. Acronis DeviceLock DLP is easily deployable through Active Directory (AD) and offers various central management consoles, based on your organization’s requirements.
    Starting Price: $615 one-time payment
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