Best Patient Engagement Software

Compare the Top Patient Engagement Software as of October 2026

What is Patient Engagement Software?

Patient engagement software empowers healthcare providers to actively involve patients in their own care by facilitating communication, education, and interaction. It offers tools like appointment reminders, secure messaging, personalized health content, and patient portals to keep patients informed and engaged. This software often integrates with electronic health records (EHR) to provide seamless access to medical information and track patient progress. By enhancing communication and convenience, patient engagement software improves adherence to treatment plans and overall satisfaction. Ultimately, it helps healthcare organizations foster stronger patient-provider relationships and better health outcomes. Compare and read user reviews of the best Patient Engagement software currently available using the table below. This list is updated regularly.

  • 1
    AdvancedMD

    AdvancedMD

    AdvancedMD

    AdvancedMD is a comprehensive cloud-based medical office management software designed to streamline operations for private healthcare practices. It combines practice management, EHR, and patient engagement tools into a unified platform. The AI Clinical Assistant powers ambient listening, auto-transcription, and chart action items to eliminate documentation burden. AI-generated pre-visit summaries, insurance card capture, and AI Narrative Insights automate clinical, financial, and administrative workflows. AdvancedMD enables providers to focus on patient care by minimizing repetitive tasks. The platform supports revenue cycle management via a multi-clearinghouse model — including Waystar — improving billing accuracy and cash flow. Password Breach Detection and secure AWS cloud hosting keep practice data protected and accessible from any device, anywhere. It delivers an integrated, intelligent solution that enhances productivity, patient outcomes, and practice performance.
    Starting Price: $321 - $1,070
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  • 2
    RXNT

    RXNT

    RXNT

    RXNT is an ambulatory healthcare technology pioneer that empowers medical practices and healthcare organizations to succeed and scale through innovative, data-backed, AI-powered software. Our fully-integrated, ONC-certified suite of medical software—like Clinical EHRs, Practice Management, Medical Billing and RCM, E-Prescribing, Practice Scheduling, Patient Portal, and more—optimizes clinical outcomes and RCM for your practice. Used by tens of thousands of medical professionals—from large physician practices to medical billing companies—to drive growth, streamline business operations, and improve patient care across all 50 U.S. states. Our unified “Full Suite” system employs a secure, central database so your data passes through every product in real-time from anywhere, and more than 135 million prescriptions have been transmitted and over $10 billion in claims have been processed using RXNT.
    Starting Price: $126/month
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  • 3
    Clinicea

    Clinicea

    Clinicea

    We're the best all-in-one, cloud-based, clinic management platform for growing, ambitious clinics. Clinicea is loved for its unique technology that can replicate paper to generate a super-specialised EMR for you. Deploy virtual assistants to get questionnaires filled, and consents signed. Already in use by 40 specialities across 5 continents. Engage 24x7. Deploy white labelled tools for Online Bookings, Patient Portals, Auto-Invoicing. There’s lots more. No apps, no downloads, just a click. Comprehensive, easy and does it all. Take a demo and see live what the next-generation technology can do for you.
    Starting Price: $59 per user per month
  • 4
    OptiMantra

    OptiMantra

    OptiMantra

    OptiMantra is an EMR and practice management platform focused on helping integrative and wellness practices. It serves individual and multi-modality group practices of direct and primary care providers, acupuncturists, nurse practitioners, naturopaths, chiropractors, massage therapists, PTs, dieticians and nutritionists, aesthetics, and others across the US and Canada. It is a HIPAA and PHIPA-compliant platform and is highly adaptable and robust - it includes online appointment booking, patient messaging and email reminders, a patient portal, intake forms and customizable charting, integrated payment processing, integrated labs and imaging, insurance billing, in-program tele-health, inventory management, and more. The platform is cloud-based and accessible and usable via any desktop, laptop, tablet or phone with internet access.
    Starting Price: $99 per month
  • 5
    Medesk

    Medesk

    Medesk

    Ideal for medical practitioners and private clinics, it is a cloud-based platform that streamlines your practice workflow, helping you attract and retain more patients at a lower cost. Medesk offers video consultations, in-built EHR, a schedule integrated with Google Calendar and iCal, online booking and appointment reminders, powerful analytics, and payment and deposit options. Medesk has developed ready-made solutions for GPs, mental health, allied health, and hair loss practitioners. Medesk allows you to automate the patient engagement process with the following tools: – Transparent online booking with convenient time slots available –Adding patient contact details straight to their EHR for immediate use – Automated confirmation emails and textsright after booking – Schedule reminders to cut down on cancellations and DNAs
    Starting Price: $15.00/month
  • 6
    Spruce Health

    Spruce Health

    Spruce Health

    Modern healthcare communication. Spruce is the simplest and most powerful way for patients, healthcare providers, and other partners in health to connect and communicate. Spruce integrates your existing communication methods with new tools, all in one easy-to-use inbox. One supercharged team inbox for all communication. With Spruce, you can communicate with both your teammates and your patients in one HIPAA-compliant inbox. Managing patient requests, listening to voicemails, and responding quickly is easy when everything is all in one place. Reach patients with the right message at the right time. Great care starts with a proactive approach. With Spruce, you can effectively reach patients before a problem turns into an emergency – helping you build stronger relationships and deliver more efficient care. With virtual care and complex workflow automation, you and your team can cover more ground and avoid unnecessary repetition.
    Starting Price: $24 per user per month
  • 7
    Mend

    Mend

    Mend

    Mend is an enterprise-grade patient engagement and telehealth platform designed to help healthcare organizations profitably scale their practice and care for more patients. Founded in 2014, Mend is on a mission to revolutionize healthcare delivery so that every patient can receive extraordinary care. Mend makes it easy for healthcare providers to securely and efficiently communicate with their patients and colleagues, without concerns of violating HIPAA compliance or misplacing patient information. Mend provides integrated in-office and virtual care experiences for over 100 specialties with more than 5 million patients. Mend's comprehensive platform works hand-in-hand with all major EHR and PMS software to facilitate more than 400,000 telehealth visits per month, increase patient satisfaction by up to 23%, reduce no-show rates as low as 4%, radically improve staff productivity, and help providers drive more revenue through better patient attendance.
  • 8
    MAP Health Management

    MAP Health Management

    MAP Health Management

    Addiction and other behavioral health conditions generally lack the long-term support and engagement required to achieve better outcomes. Since 2011, MAP has harnessed the power of telehealth to help support tens of thousands of individuals and families through peer-led support. - A Peer Specialist is someone who has walked a mile in the shoes of the person they are supporting. - MAP’s Peer Specialists are all extensively trained, certified and have lived experience in behavioral health issues and/or addiction. - Peer support is not a replacement for other services, it enhances and reinforces them. MAP Care Solutions, a leader in Peer Support, recognizes connecting those with shared experience is critical to improving outcomes. PeerLink® aims to bridge those connections quickly by offering on-demand Peer Support.
  • 9
    Advantage SMART Practice

    Advantage SMART Practice

    Compulink Healthcare Solutions

    All-in-one EHR and practice management solutions using the power of data to improve clinical and financial results. Comprehensive. Customizable. Adapts to your style of practice. Real-time video chat for you and your patients. Deliver personalized care from almost anywhere. Company's EHR identifies best code for maximum reimbursement. Learn how our specialty specific EHR saves you time, money, and streamlines patient flow. Do less work and get paid more, faster with our expert billing service.
  • 10
    NeuroFlow

    NeuroFlow

    NeuroFlow

    NeuroFlow is a digital health company combining workflow automation, consumer engagement solutions, and applied AI to promote behavioral health integration in all care settings. NeuroFlow’s suite of HIPAA-compliant, cloud-based tools simplify remote patient monitoring, enable risk stratification, and facilitate collaborative care. With NeuroFlow, health care organizations can finally bridge the gap between mental and physical health in order to improve outcomes and reduce the cost of care.
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