Compare the Top e-Prescribing Software for Cloud as of October 2026

What is e-Prescribing Software for Cloud?

e-Prescribing software provides physicians and medical professionals with a platform to generate and send electronic prescription orders to pharmacies and their clients. Compare and read user reviews of the best e-Prescribing software for Cloud currently available using the table below. This list is updated regularly.

  • 1
    RXNT

    RXNT

    RXNT

    RXNT is an ambulatory healthcare technology pioneer that empowers medical practices and healthcare organizations to succeed and scale through innovative, data-backed, AI-powered software. Our fully-integrated, ONC-certified suite of medical software—like Clinical EHRs, Practice Management, Medical Billing and RCM, E-Prescribing, Practice Scheduling, Patient Portal, and more—optimizes clinical outcomes and RCM for your practice. Used by tens of thousands of medical professionals—from large physician practices to medical billing companies—to drive growth, streamline business operations, and improve patient care across all 50 U.S. states. Our unified “Full Suite” system employs a secure, central database so your data passes through every product in real-time from anywhere, and more than 135 million prescriptions have been transmitted and over $10 billion in claims have been processed using RXNT.
    Starting Price: $126/month
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  • 2
    AdvancedMD

    AdvancedMD

    AdvancedMD

    AdvancedMD is a comprehensive cloud-based medical office management software designed to streamline operations for private healthcare practices. It combines practice management, EHR, and patient engagement tools into a unified platform. The AI Clinical Assistant powers ambient listening, auto-transcription, and chart action items to eliminate documentation burden. AI-generated pre-visit summaries, insurance card capture, and AI Narrative Insights automate clinical, financial, and administrative workflows. AdvancedMD enables providers to focus on patient care by minimizing repetitive tasks. The platform supports revenue cycle management via a multi-clearinghouse model — including Waystar — improving billing accuracy and cash flow. Password Breach Detection and secure AWS cloud hosting keep practice data protected and accessible from any device, anywhere. It delivers an integrated, intelligent solution that enhances productivity, patient outcomes, and practice performance.
    Starting Price: $321 - $1,070
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  • 3
    OptiMantra

    OptiMantra

    OptiMantra

    OptiMantra is an EMR and practice management platform focused on helping integrative and wellness practices. It serves individual and multi-modality group practices of direct and primary care providers, acupuncturists, nurse practitioners, naturopaths, chiropractors, massage therapists, PTs, dieticians and nutritionists, aesthetics, and others across the US and Canada. It is a HIPAA and PHIPA-compliant platform and is highly adaptable and robust - it includes online appointment booking, patient messaging and email reminders, a patient portal, intake forms and customizable charting, integrated payment processing, integrated labs and imaging, insurance billing, in-program tele-health, inventory management, and more. The platform is cloud-based and accessible and usable via any desktop, laptop, tablet or phone with internet access.
    Starting Price: $99 per month
  • 4
    Nexus EHR

    Nexus EHR

    Nexus Clinical

    Reclaiming the Patient-Provider Connection. Nexus EHR was built on a single premise: doctors should be healers, not data entry clerks. In an era of high burnout, Nexus provides a streamlined, intelligent interface that prioritizes the patient over the platform. By integrating native AI technology with specialty-specific logic, we’ve created an EHR that feels less like a database and more like an expert clinical partner. Nexus EHR includes Advanced e-Prescribing & ECPS capabilities, lab interface and much more. The AI Difference: Native Scribing The centerpiece of the Nexus experience is our Native AI Scribe. Unlike third-party add-ons, our scribe is woven into the fabric of the EHR. Automatically generates high-quality clinical notes by capturing natural dialogue. Specialty Nuance: Our AI scribe can work with terminologies in Neurology, Cardiology, Orthopedics and more than 25 specialties. Nexus offers dedicated modules tailored to the workflows of high-stakes specialties.
    Starting Price: $300 per physician/month
  • 5
    Practice Mate

    Practice Mate

    Office Ally

    Practice Mate by Office Ally is a comprehensive practice management solution used by over 25,000 healthcare organizations. It simplifies revenue cycle management and assists in HIPAA-compliant recordkeeping for new and existing practices. Its user-friendly interface offers easy billing management that checks eligibility and benefits and manages claim submission and tracking. Its seamless integration with other Office Ally solutions provides additional functionality such as patient intake, reminders, e-prescriptions, and more. With no cost, commitment, or implementation, you can get started today to help reduce unnecessary administrative tasks, enhance provider job satisfaction, and improve the overall patient experience.
    Starting Price: $0
  • 6
    DrChrono

    DrChrono

    DrChrono

    Increase the efficiency of your medical practice with an all-in-one practice management, electronic health records, and medical billing platform from DrChrono. With its modern and simple interface and dozens of advanced features, DrChrono empowers medical practitioners to better serve their patients. Users can easily schedule patient appointments, check and edit patient charts, and manage billing with ease.
  • 7
    Tebra

    Tebra

    Tebra

    Independent practices need complete solutions to maximize patient and provider well-being. While each Tebra product is purpose-built to modernize and optimize every step of the patient-practice journey, the combined platform delivers a complete operating system that provides added value for providers and patients alike. Power your connected practice with everything you need to attract new patients and keep current ones through the power of digital presence. Empower patients through every communication touchpoint and deliver a uniquely frictionless experience and convenient access that builds trust and a healthier practice. A modern, certified EHR solution built for the needs of today’s provider, delivering everything your practice needs. This includes robust charting, streamlined documentation, a comprehensive view of patients and their history, eRx, eLabs, telehealth, and more, allowing providers control of how they deliver care.
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