Best Nonprofit B2B Gateways
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Compare the Top Nonprofit B2B Gateways as of October 2026
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What are Nonprofit B2B Gateways?
B2B gateways are platforms that facilitate the secure exchange of business documents, transactions, and data between organizations across supply chains, partner networks, and trading ecosystems. These solutions enable interoperability between different business systems by supporting standards such as EDI, XML, APIs, AS2, and other communication protocols. B2B gateways often provide capabilities for message translation, routing, validation, security, monitoring, and compliance to ensure reliable business-to-business communications. Many platforms integrate with ERP systems, procurement software, logistics applications, and partner management solutions to automate transaction workflows. By streamlining partner connectivity and data exchange, B2B gateways help organizations improve operational efficiency, reduce manual processing, and strengthen supply chain collaboration. Compare and read user reviews of the best Nonprofit B2B Gateways currently available using the table below. This list is updated regularly.
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MOVEit
Progress Software
Progress MOVEit software is an enterprise Managed File Transfer (MFT) platform for IT teams that need secure, auditable and automated file transfers across hybrid environments. It supports FTP/S, SFTP, HTTPS, SMTP/POP3 and CIFS/SMB/UNC with native cloud endpoint connectors, centralized administration, granular role-based access control, encryption in transit and at rest and tamper-evident audit logging for traceability. MOVEit Transfer provides MFT server capabilities and can be deployed on-premises or in hybrid configurations with MOVEit Cloud, a fully managed SaaS option. MOVEit Automation enables scheduling, event-driven workflows and integrations with internal and external systems to standardize recurring transfers without relying on brittle scripts. Designed for enterprise and regulated use cases, MOVEit provides the protocol support, deployment flexibility and operational visibility needed to run high-volume, mission-critical file transfer operations. -
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GoAnywhere MFT
Fortra
GoAnywhere MFT provides secure managed file transfer for enterprises. Deployable on-premise, in the cloud, or in hybrid environments, GoAnywhere MFT software enables organizations to exchange data among employees, customers, and trading partners, as well as between systems, securely. GoAnywhere MFT was a recipient of the Cybersecurity Excellence Award for Secure File Transfer. -
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Globalscape’s Enhanced File Transfer (EFT) platform is a comprehensive, user-friendly managed file transfer (MFT) software. Thousands of Windows-Centric Organizations trust Globalscape EFT for their mission-critical file transfers. EFT provides security and compliance combined with powerful tools for automation, collaboration, and analysis. It is available in cloud/SaaS (EFT Arcus) and on-premises EFT deployments. Unlike traditional file transfer software, EFT provides enterprise-level data security as well as data transfer automation through integration with back-end systems. Administration is easy, yet detailed enough for complete control of your file transfer system. EFT replaces insecure legacy systems, homegrown servers, manual delivery, expensive leased lines, and VANs with a top-performing, scalable alternative.
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JSCAPE MFT Server
Redwood Software
JSCAPE by Redwood is a secure managed file transfer (MFT) solution that consolidates fragmented tools, custom scripts and siloed processes into one reliable platform. It handles any file size and any protocol — SFTP, FTP/S, HTTP/S, AS2, OFTP2, WebDAV, and more — while keeping you compliant with HIPAA, PCI DSS, SOX, GDPR and GLBA. JSCAPE delivers enterprise-grade security, backed by an unblemished track record since 1999 and active third-party certifications such as SOC 2 Type 1 and Type 2, ISO 27001, Drummond Certified™, FIPS 140-2 and 140-3 validated encryption. Low-code automation triggers and workflows have allowed 1,000+ teams in 57+ countries to orchestrate complex file transfers across any platform (Windows, Mac, Linux, Solaris) and environment (self-hosted, containerized or SaaS), without additional middleware. Additionally, 24/7/365 expert technical support with an 8-minute median response time is included in every plan. Schedule a free demo today! -
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AS2 Gateway
Aayu Technologies LLC
Assured Trading with AS2 to Digitalize your Business. AS2 Gateway provides a B2B trading platform for organizations trading over the AS2 protocol, with a simplified and intuitive interface concealing the underlying complexities from end users. AS2 Gateway is fully compliant with the AS2 specification published by Drummond and Morberg, while ensuring the security of exchanged data via encryption, digital signature validation and guaranteed integrity through MIC (Message Integrity Check) hashing. Data security is further enhanced by utilizing the latest SSL/TLS channelling technologies as a supplementary security standard.Starting Price: $59 per month
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