Best Application Control Software for Mac

Airlock Digital is an application control solution that enforces a Deny by Default security posture. It enables organizations to define trusted applications, scripts, libraries, and processes at a granular level using file hash, path, publisher, or parent process. Only those explicitly defined as trusted are allowed to execute. The platform supports Windows, macOS, and Linux systems, including legacy operating systems and operational technology (OT) environments. Airlock Digital includes allowlisting and blocklisting capabilities, integrated file reputation checks via VirusTotal, and detailed logging for audit and compliance. Exception management is supported through features such as rule-based overrides and time-bound One-Time Passwords (OTPs). Centralized policy management allows consistent enforcement across large and distributed environments. The platform is available as an on-premises deployment, in the cloud, or as a managed hosted service.

Securden EPM helps enforce granular application control on endpoints through allowlisting and blocklisting. Grant temporary access to specific applications through request-release workflows. Track application usage with pinpoint accuracy using the Securden Audit Engine. Restrict users from downloading and installing malicious applications through robust privilege management.

ManageEngine Endpoint Central enforces comprehensive application control across every managed endpoint ensuring only trusted, approved applications can execute while blocking unauthorized, untrusted, and potentially harmful software before it runs. A default-deny approach with intelligent allowlisting prevents malicious applications, unauthorized tools, and unapproved software from executing across the endpoint fleet significantly reducing the risk of ransomware, malware, and insider threats. Administrators can create and manage allowlists and blocklists centrally, with granular policy controls targeting specific device groups, user roles, and organizational units. Application discovery provides complete visibility into all software running across the network before enforcement, ensuring legitimate business applications are accounted for and policies are built on real usage data rather than assumptions that could block productivity or leave gaps in security coverage.

ThreatLocker is a Zero Trust Platform that prevents cyber threats by blocking unknown applications, enforcing least privilege, and controlling what can run across your environment. Using Allowlisting, Ringfencing, Network Control, and more, ThreatLocker stops ransomware, zero-day attacks, and unauthorized activity before execution, rather than relying on detection after the fact. Built for modern IT and cybersecurity teams, the platform delivers centralized visibility and policy management across endpoints, users, and applications. ThreatLocker reduces attack surface, limits lateral movement, and supports compliance with detailed audit logs. With fast deployment, a large built-in application library, and streamlined approvals, organizations can strengthen security while minimizing operational overhead and maintaining business continuity.

Securden Unified PAM is a privileged access security solution that lets you discover, centrally store, organize, share, manage, and keep track of all privileged identities, passwords, keys, documents, and other identities. It helps you establish a centralized password management system, automate management with approval workflows, control ‘who’ can access ‘what’, monitor, and record all access to critical IT assets, and enforce password security best practices. The major modules of Securden Unified PAM are password management, privileged account management, secure remote access, application control, endpoint privilege management, privileged session management, and SSH key management. The platform supports compliance with NIS2, DORA, NIST, PCI-DSS, HIPAA, and ISO-IEC 27001. Installation typically takes only a few minutes, and a complete production-ready PAM can be achieved in less than a month with Securden Unified PAM.

Privilege Manager is the most comprehensive endpoint privilege elevation and application control solution that operates at cloud speed and scale. You can prevent malware from exploiting applications by removing local administrative rights from endpoints and implementing policy-based application controls. Privilege Manager prevents malware attacks without causing any end user friction that slows productivity. Available both on-premises and in the cloud, enterprises and fast-growing teams can manage hundreds of thousands of machines through Privilege Manager. With built-in application control, real-time threat intelligence, and actionable reporting, it is easier than ever to manage endpoints and demonstrate compliance with least privilege policies to executives and auditors.

PC Matic Pro's application whitelisting is a critical preventative layer of cyber-protection that resides on top of other endpoint security solutions. zero trust whitelisting solutions prevent hacking and cyber-attacks. Block all malware, ransomware, and malicious scripts from executing. Protect your business data, users, and network with our whitelist cybersecurity solution. PC Matic Pro represents a long overdue shift in the cybersecurity industry to absolute prevention. Today's threats to critical infrastructure, industry, and all levels of government demand nothing less. PC Matic Pro provides a patented default-deny security layer at the device that blocks all unknown executions without introducing headaches for IT. Unlike traditional security solutions, customer infections aren’t required to strengthen the whitelist architecture. Local overrides can be added after prevention with a focus on accuracy and without concern for responding to an already active infection.

Ivanti offers integrated IT management solutions designed to automate and secure technology across organizations. Their Unified Endpoint Management platform provides intuitive control from a single console to manage any device from any location. Ivanti’s Enterprise Service Management delivers actionable insights to streamline IT operations and improve employee experiences. The company also provides comprehensive network security and exposure management tools to protect assets and prioritize risks effectively. Trusted by over 34,000 customers worldwide, including Conair and City of Seattle, Ivanti supports secure, flexible work environments. Their solutions enable businesses to boost productivity while maintaining strong security and operational visibility.