Best Small Business Antivirus Software

Compare the Top Small Business Antivirus Software as of October 2026

What is Small Business Antivirus Software?

Antivirus software helps protect computers, networks, and mobile devices from malicious threats such as viruses, malware, ransomware, spyware, and trojans. These platforms typically scan files and programs for known threats, block suspicious activity, and remove harmful software from systems. Antivirus software often includes real-time protection, automatic updates, and scheduled scans to ensure ongoing security. Additionally, many antivirus programs offer web protection, email scanning, and firewall features to prevent cyber-attacks and data breaches. By using antivirus software, individuals and businesses can safeguard their devices, maintain privacy, and ensure the integrity of their data. Compare and read user reviews of the best Small Business Antivirus software currently available using the table below. This list is updated regularly.

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    ManageEngine Endpoint Central
    ManageEngine Endpoint Central includes next-generation antivirus (NGAV) and anti-ransomware protection that goes beyond traditional signature-based detection using behavioral analysis and AI-driven intelligence to identify and block known, unknown, and zero-day threats before they execute on managed endpoints. Unlike conventional antivirus solutions that rely solely on known virus definitions, Endpoint Central's NGAV continuously monitors endpoint behavior to detect suspicious activity, fileless malware, and advanced attack techniques that evade traditional security tools. Ransomware-specific protection identifies encryption-like behavior in real time, isolating and neutralizing threats before they can spread across the network. Automated threat remediation restores affected files and system components, while built-in rollback capabilities reverse unauthorized changes ensuring endpoints can be restored to a clean, trusted state with minimal disruption to business operations.
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    Starting Price: $1.09/endpoint/month
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  • 2
    Heimdal Endpoint Detection and Response (EDR)
    Heimdal® Endpoint Detection and Response is our proprietary multi-solution service providing unique prevention, threat-hunting, and remediation capabilities. It combines some of the most advanced threat-hunting technologies: - Next-Gen Antivirus - Privileged Access Management - Application Control - Ransomware Encryption Protection - Patch & Asset Management - Email Security - Remote Desktop - Threat Prevention ( DNS based ) - Threat Hunting & Action Center With 9 modules working together seamlessly under one convenient roof, all within one agent and one platform, Heimdal Endpoint Detection and Response grants you access to all the essential cybersecurity layers your business needs to protect itself against both known and unknown online and insider threats. Our state-of-the-art product empowers you to quickly and effortlessly respond to sophisticated malware with stunning accuracy, protecting your digital assets and your reputation in the process as well.
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    Starting Price: $0/month
  • 3
    PC Matic

    PC Matic

    PC Matic

    PC Matic Pro's application whitelisting is a critical preventative layer of cyber-protection that resides on top of other endpoint security solutions. zero trust whitelisting solutions prevent hacking and cyber-attacks. Block all malware, ransomware, and malicious scripts from executing. Protect your business data, users, and network with our whitelist cybersecurity solution. PC Matic Pro represents a long overdue shift in the cybersecurity industry to absolute prevention. Today's threats to critical infrastructure, industry, and all levels of government demand nothing less. PC Matic Pro provides a patented default-deny security layer at the device that blocks all unknown executions without introducing headaches for IT. Unlike traditional security solutions, customer infections aren’t required to strengthen the whitelist architecture. Local overrides can be added after prevention with a focus on accuracy and without concern for responding to an already active infection.
    Starting Price: $50 per year
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