Guidance for the surveillance of drug resistance in tuberculosis: Sixth edition
Overview
The aim of this document is to assist national tuberculosis (TB) programmes in developing the strongest possible mechanisms of surveillance for drug resistance in TB, building on more than 25 years of global experience. This starts from periodic surveys of sampled patients, moving towards an ultimate goal of continuous surveillance systems based on routine drug susceptibility testing (DST). This guidance promotes certain standardized criteria for surveillance to ensure that results are comparable within and between countries over time. The target audience of this document is national TB programmes and, in particular, the coordination team for surveillance ideally composed of the programme manager, a laboratory specialist, a logistician, and an epidemiologist/statistician.
Additional supplementary materials include:
- Editable versions of relevant annexes in Microsoft Word
- Examples of sampling approaches for different survey designs, accompanied by R codes and sample datasets
- Stata and R codes for analysis of survey datasets download from GitHub: https://github.com/GTB-DRS.
- Guidance handbook on how to apply good clinical and good data management practices for national TB surveys.
