Good day, students!
Welcome to our
science 10 class
WITH MS. ROCHELLE S.
PASTRANA
HYF?
BACKTRACK
DNA
Let's make a
word cloud!
SCIENCE
VOCAB
SCIENCE VOCAB
DNA
Deoxyribonucleic Acid
blueprint of all living things
contains hereditary material that
controls the activities of each cell
SCIENCE VOCAB
GENE EXPRESSION
use of genetic information to make
proteins
also known as protein synthesis
SCIENCE VOCAB
GENE EXPRESSION
During the expression, the messages
encoded in DNA direct all cellular
activities.
SCIENCE VOCAB
DNA REPLICATION
process during which a double-stranded
DNA molecule is copied to produce
two identical DNA molecules
SCIENCE VOCAB
BASE PAIRING
principle in which the nitrogenous
bases of the DNA molecules bond with
one another
LET'S PLAY
SCAVENGER HUNT:
I AM LOOKING FOR
YOU
SCAVENGER HUNT:
I AM LOOKING FOR
YOU
1. How did you find the activity?
2. Was it easy to look for those traits?
3. Where do you think these traits are from?
4. How were these traits expressed?
MELC
EXPLAIN HOW PROTEIN IS MADE USING
INFORMATION FROM DNA
#OOTD
• EXPLAIN THE ROLE OF DNA AND DNA
REPLICATION IN MAKING PROTEINS
• CONSTRUCT A FLOWCHART
DESCRIBING THE PROCESS OF DNA
REPLICATION
I am the
control center!
WHAT DO YOU THINK IS THE
ROLE OF DNA IN MAKING
PROTEINS AND IN GENE
EXPRESSION?
How is the DNA being replicated?
DNA Deoxyribonucleic Acid
• blueprint of all living
things
• contains hereditary
material that controls
the activities of each
cell
DNA
DNA
The sequence information in
each DNA molecule is divided
into segments called genes.
Each gene contains the
instructions for building a
particular protein.
DNA
In every cell of the body,
the DNA bears a genetic
code that determines the
traits of an organism.
WHAT DO YOU THINK IS THE
ROLE OF DNA IN MAKING
PROTEINS AND IN GENE
EXPRESSION?
The use of genetic information to make proteins is called gene
expression or protein synthesis. During the
expression, the messages encoded in DNA direct all cellular
activities.
PROTEIN SYNTHESIS
DNA
REPLICATION
How is DNA
being replicated?
How is the DNA being
replicated?
DNA REPLICATION
DNA REPLICATION IS
SEMICONSERVATIVE.
EACH STRAND IN THE DOUBLE HELIX
ACTS AS A TEMPLATE FOR SYNTHESIS OF
A NEW, COMPLEMENTARY STRAND.
DNA REPLICATION
INITIATION POLYMERIZATION/
TERMINATION
ELONGATION
• INITIATION FROM THE DNA
TEMPLATE
Enzyme involved
Helicases
3. POLYMERIZATION/
ELONGATION
Enzyme involved
DNA Polymerase
LET'S TRY THIS!
5’-AATTGGCC-
3’
LET'S TRY THIS!
5’-AATTGGCC-
3’-TTAACCGG-
3’
3.TERMINATION
Enzyme involved
Ligase
Go With the Flow
GROUP ACTIVITY
THINK-PAIR-SHARE
DON'T KEEP ME HANGING
1. What is the role of DNA in making a protein?
2. What step in the’ DNA replication allows the
DNA template to unzip?
3. How would you describe the elongation
process in DNA replication?
4. Do the base pairing of the sequence below:
ATAATCGCGCTA
SEQUENCE TO BE REPLICATED
5’-CGATAATTGGCG-3’
Initiation
With the presence of Endonucleases and
DNA
Helicases the DNA unwinds and unzips
REPLICATION
Elongation
With the presence of DNA Polymerase
base pairing will occur
Termination
DNA replication ends when converging replication
forks meet
WHAT DO YOU THINK IS THE
ROLE OF DNA IN MAKING
PROTEINS AND IN GENE
EXPRESSION?
How is the DNA being replicated?
Summary
In every cell of the body, the DNA bears
a genetic code needed for protein
synthesis which determines the traits of
an organism.
Summary
The following are the events while DNA copies itself:
Step 1: An enzyme helicase breaks the bond between nitrogenous
bases. The two strands of DNA split.
Step 2: The bases attached to each strand then pair up with the free
nucleotides found in the cytoplasm.
Step 3: The complementary nucleotides are added to each strand by
DNA polymerase to form new strands. Two new DNA molecules, each
with a parent strand are formed.
KEEP IN MIND AND IN YOUR HEART
Trust the process.
Thank you, students!