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Second Week of Development

During the second week of development, the trophoblast differentiates into the inner cytotrophoblast layer and outer syncytiotrophoblast layer. This establishes the utero-placental circulation through the formation of primary stem villi and intervillous spaces between days 9-13. The embryoblast divides into the hypoblast and epiblast layers, forming the bilaminar germ disc. The hypoblast forms the primary yolk sac and lines the blastocyst cavity, now called the primary yolk sac. The primary extra-embryonic mesoderm and coelom form through the delamination of the primary yolk sac and amniotic cavity, establishing the connecting stalk.

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376 views

Second Week of Development

During the second week of development, the trophoblast differentiates into the inner cytotrophoblast layer and outer syncytiotrophoblast layer. This establishes the utero-placental circulation through the formation of primary stem villi and intervillous spaces between days 9-13. The embryoblast divides into the hypoblast and epiblast layers, forming the bilaminar germ disc. The hypoblast forms the primary yolk sac and lines the blastocyst cavity, now called the primary yolk sac. The primary extra-embryonic mesoderm and coelom form through the delamination of the primary yolk sac and amniotic cavity, establishing the connecting stalk.

Uploaded by

soumyadebsamanta2
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© © All Rights Reserved
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Download as PPTX, PDF, TXT or read online on Scribd
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Second week of development

Changes in the Trophoblast–

Differentiates into-

Cytotrophoblast–inner layer

Syncytiotrophoblast– outer layer


Establishment of utero-placental circulation–

Formation of primary stem villi and intervillous spaces

These changes occur between 9th and 13th day after


fertilization
Changes in the Embryoblast–

It divides into two layers–

Hypoblast or primary endoderm

Epiblast or primary ectoderm

Formation of bilaminar germ disc


Formation of primary yolk sac

A layer of flattened cells arising from the hypoblast


line the inner side of blastocyst cavity
Heuser’s membrane

Now blastic cavity lined all sides by cells of


endodermal origin–primary yolk sac.
Formation of primary extra-embryonic mesoderm and
extra-embryonic coelom–

Delamination of primary yolk sac and the amniotic


cavity from the trophoblast except the caudal end of the
germ disc– formation of connecting stalk.

Conversion of primary yolk sac into secondary yolk


sac—size is reduced and lined by new layer of cell.

The wall of yolk sac is the first site of formation of


blood.

It forms the endodermal lining of gastrointestinal tract


Formation of prechordal plate–

At one circular areanear the margin of the disc


cubical cells of the hypoblast become columnar.

This area is called prechordal plate.

It establishes cephalo-caudal axis of the embryo.

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