Global Pandemic
Global Pandemic
Third Cholera Pandemic (1852-1860): Cholera spread from India to Europe, Africa, and
North America, causing tens of millions of deaths due to contaminated water sources.
Spanish Flu (1918-1919): The H1N1 influenza virus caused this devastating pandemic,
infecting about one-third of the global population and killing an estimated 50 million
people worldwide.
3. Omicron variant(B.1.1.529):
The Omicron variant was detected in India in late 2021 which was a weaker version of delta variant.
This variant resulted in 3RD wave of covid in India with 2 Lakh cases being recorded everyday.
COVID CASES AND DEATHS
CASES DEATHS
COVID-19 EFFECT ON INDIAN
ECONOMY
GDP Contraction: India's economy experienced a sharp contraction in GDP growth due to lockdowns and
restrictions imposed to control the spread of the virus. In the fiscal year 2020-2021, India's GDP contracted
by around 7.3%, marking the first contraction in decades.
Unemployment: The pandemic led to widespread job losses and reduced income for many workers,
particularly in sectors like construction, manufacturing, and informal services. Urban areas and daily-wage
laborers were especially hard hit.
Informal Sector: India has a large informal economy, and many workers in this sector faced income losses
and job insecurity due to lockdowns and reduced economic activity.
Trade and Supply Chains: Disruptions in global supply chains and international trade had an impact on
sectors dependent on imports and exports. The closure of factories and reduced shipping affected both
production and demand.
Tourism and Hospitality: The tourism and hospitality sectors suffered immensely due to travel restrictions
and lockdowns. Hotels, airlines, restaurants, and related businesses faced significant revenue losses.
COVID-19 EFFECT ON GLOBAL
ECONOMY
Global Recession: The pandemic triggered a severe global economic downturn, with most countries
experiencing a contraction in GDP growth. Lockdowns, travel restrictions, and reduced consumer spending
led to decreased economic activity.
Unemployment and Income Loss: Many businesses faced closures and reduced operations, leading to
widespread job losses and income reduction for workers. Sectors like tourism, hospitality, retail, and
entertainment were particularly hard hit.
Trade Impact: International trade suffered as a result of restrictions on movement and port closures.
Reduced demand and logistical challenges hindered the movement of goods and services across borders.
Oil Price Crash: The pandemic, coupled with a price war between major oil-producing countries, led to a
dramatic decline in oil prices. This had a significant impact on oil-exporting nations and the energy sector.
Financial Markets Volatility: Global financial markets experienced significant volatility in the early stages
of the pandemic. Stock markets saw rapid declines followed by periods of recovery, reflecting uncertainty
and investor sentiment.
DEVELOPMENT OF VACCINES
Research and Preclinical Studies
Vaccine Platform Selection
Clinical Trials
Emergency Use Authorization and Approval
Manufacturing and Distribution
NOTABLE VACCINES
Pfizer-BioNTech
Moderna
Oxford-AstraZeneca(COVISHIELD)
Johnson & Johnson
Sinopharm and Sinovac
Covaxin
INDIAN VACCINES
COVAXIN
Bharat Biotech International Limited (BBIL) is an Indian multinational biotechnology
company headquartered in the city of Hyderabad, India.
On June 29, 2020, the company got permission to conduct Phase 1 and Phase 2 clinical trials
in India for a developmental COVID-19 vaccine.
Bharat biotech charged ₹600 for the government and ₹1200 for individuals and earned a
profit of ₹75750 crores.
COVISHIELD
Developed in the United Kingdom by Oxford University and British-Swedish company
AstraZeneca.
On 30 December 2020, the vaccine was first approved for use in the UK vaccination
program.
The vaccine costs around US$3 to US$4 per dose to manufacture.
Serum institute of India produced the vaccines in India for local use and charged ₹700 for
the Government and up to ₹1500 for individuals and earned a profit of ₹25646 Crores.
VACCINATION EFFICACY AND SAFETY
Efficacy refers to how well a vaccine prevents disease in a controlled
clinical trial setting.
mRNA vaccines, such as Pfizer-BioNTech and Moderna, have shown
efficacy rates of around 90% to 95% in preventing symptomatic COVID-19
infection.
Viral vector vaccines, like Oxford-AstraZeneca and Johnson & Johnson,
have shown efficacy rates of around 60% to 90% in preventing
symptomatic COVID-19 infection.
Common side effects of COVID-19 vaccines include pain or swelling at the
injection site, fatigue, headache, muscle pain, chills, fever, and nausea.
These side effects are usually mild to moderate and resolve within a few
days.
ROLE & SIGNIFICANCE OF VACCINATION
70.3% of the world population has received at least one dose of a COVID-19 vaccine.
13.48 billion doses have been administered globally, and 158,616 are now
administered each day.