Glomerulonefritis

The document discusses glomerulonefritis (glomerular disease), including its definition, classification, clinical presentation, treatment, and complications. It defines glomerular disease by clinical presentation and histologic findings. It classifies glomerular disease into 8 main types including minimal change disease, focal segmental glomerulosclerosis, membranous glomerulonephritis, and rapidly progressive glomerulonephritis. Treatment depends on disease type but generally includes controlling proteinuria, hypertension, edema and immunosuppressive drugs. Complications can include end stage renal disease if not properly treated.

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Glomerulonefritis

Uploaded by

yulia syarifa

We take content rights seriously. If you suspect this is your content, claim it here.

Available Formats

Download as PPTX, PDF, TXT or read online on Scribd

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Glomerulonefritis

Overview
Anatomy Physiology Pathophysiology

Epidemiology Diagnosis Workup

Definition Treatment

Clinical Presentation Complication

Clasification Prognosis

Etiology Prevention
Anatomy
Physiology
Anatomy
Physiology
Anatomy
Physiology
Anatomy
Physiology
Definition
The glomerular diseases are defined by their clinical presentations and the
histologic findings associated with the diseases.

Primer sekunder
• Systemic Disease impacts the kidney
Clnincal
Presentation
Clnincal
Presentation
Clnincal
Presentation
Clnincal
Presentation
Clnincal
Presentation
Clnincal
Presentation
Clasification – 1. Minimal
Change Disease
Clasification – 1. Minimal
Change Disease
Clasification – 1. Minimal
Change Disease
Clasification – 2. Focal
Segmental Glomerulosklerosis
Clasification – 2. Focal
Segmental Glomerulosklerosis
Clasification – 2. Focal
Segmental Glomerulosklerosis
Clasification – 2. Focal
Segmental Glomerulosklerosis
Clasification – 2. Focal
Segmental Glomerulosklerosis
Clasification – 2. Focal
Segmental Glomerulosklerosis
Clasification – 3. Membranous
Glomerulonefritis
Clasification – 3. Membranous
Glomerulonefritis
Clasification – 3. Membranous
Glomerulonefritis
Clasification – 3. Membranous
Glomerulonefritis
Clasification – 4.
Membranoploriperativeus
Glomerulonefritis
Clasification – 4.
Membranoploriperativeus
Glomerulonefritis
Clasification – 4.
Membranoploriperativeus
Glomerulonefritis
Clasification – 4.
Membranoploriperativeus
Glomerulonefritis
Clasification – 4.
Membranoploriperativeus
Glomerulonefritis
Clasification – 4.
Membranoploriperativeus
Glomerulonefritis
Clasification – 4.
Membranoploriperativeus
Glomerulonefritis
Clasification – 4.
Membranoploriperativeus
Glomerulonefritis
Clasification – 4.
Membranoploriperativeus
Glomerulonefritis
Clasification – 4.
Membranoploriperativeus
Glomerulonefritis
Clasification – 5. Post Streptococal
Glomerulonefritis
Clasification – 5. Post Streptococal
Glomerulonefritis
Clasification – 5. Post Streptococal
Glomerulonefritis
Clasification – 5. Post Streptococal
Glomerulonefritis
Clasification – 6. Ig A Nefropathy
Clasification – 6. Ig A Nefropathy
Clasification – 6. Ig A Nefropathy
Clasification – 6. Ig A Nefropathy
Clasification – 6. Ig A Nefropathy
Clasification – 6. Ig A Nefropathy
Clasification – 6. Ig A Nefropathy
Clasification – 6. Ig A Nefropathy
Clasification – 6. Ig A Nefropathy
Clasification – 6. Ig A Nefropathy
Clasification – 6. Ig A Nefropathy
Clasification – 7. Lupus Nefritis
Clasification – 7. Lupus Nefritis
Clasification – 7. Lupus Nefritis
Clasification – 7. Lupus Nefritis
Clasification – 7. Lupus Nefritis
Clasification – 7. Lupus Nefritis
Clasification – 7. Lupus Nefritis
Clasification – 8. Rapidly
Progresive Glomerulonefritis
Clasification – 8. Rapidly
Progresive Glomerulonefritis
Clasification – 8. Rapidly
Progresive Glomerulonefritis
Clasification – 8. Rapidly
Progresive Glomerulonefritis
Clasification – 8. Rapidly
Progresive Glomerulonefritis
Clasification – 8. Rapidly
Progresive Glomerulonefritis
Clasification – 8. Rapidly
Progresive Glomerulonefritis
Treatment – General Treatment
1. Proteinuria Ace-I, ARB

2. Hypertension Non Pharmacologic

• Life Style Modification
• Stop Smoking
• Exercise
Pharmacologic
• Ace-I, ARB
• CCB
• Beta Blocker
•
Treatment – General Treatment
3. Edema Sodium Retention
Thiazide
Loop Diuretik
4. Hyperlipidemia Statin
Gemfibrozil
5. Hypercoagulability Warfarin
LMWH
Treatment – Spesific Treatment
1. Imunosupresan Metylprednisolone
Cylosporine
Azatioprine
MMF

2. Plasmapharesis
Treatment – Spesific Treatment
1. Minimal High Dose Metylprednisolon
4-16wk, extended 5-6mo
Change 2nd : Cyclosporine
Disease Cyclophosphamide
Tacrolimus
MMF
Treatment – Spesific Treatment
2. Focal High Dose Metylprednisolon
Segmental 12-16wk, extended 5-6mo

Calcineruin Inhibitor :
Cyclosporine
Glomerulosklero Tacrolimus

sis
Treatment – Spesific Treatment
Membranous Ace-I, ARB
Glomerulonefritis
Persisten Proteinuria
- Steroid 6mo
- Cyclophosphamid
- CNI : Cyclosporine
Tacrolimus
- MMF
Treatment – Spesific Treatment
MembranoploriperativeusSecondary Etiology ?
lomerulonefritis No Specific Treatment

Steroid?
Imunosupresan?
Treatment – Spesific Treatment
Post Streptococal Eradication Infection