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Spatial and Temporal Summation

Summation is the process by which multiple stimuli can generate a response that a single stimulus alone cannot. There are two types of summation in neurons: spatial summation and temporal summation. Spatial summation involves the additive effect of signals from different presynaptic neurons on the postsynaptic neuron simultaneously. Temporal summation involves the additive effect of sequential signals from a single presynaptic neuron, occurring rapidly one after another. The difference is that spatial summation involves multiple synapses activating at once, while temporal summation involves a single synapse activating repeatedly over time.

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59 views

Spatial and Temporal Summation

Summation is the process by which multiple stimuli can generate a response that a single stimulus alone cannot. There are two types of summation in neurons: spatial summation and temporal summation. Spatial summation involves the additive effect of signals from different presynaptic neurons on the postsynaptic neuron simultaneously. Temporal summation involves the additive effect of sequential signals from a single presynaptic neuron, occurring rapidly one after another. The difference is that spatial summation involves multiple synapses activating at once, while temporal summation involves a single synapse activating repeatedly over time.

Uploaded by

SONGA Amri
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PPTX, PDF, TXT or read online on Scribd
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summation

•Definition: the process whereby


multiple stimuli can produce or
generate a response (in a muscle,
nerve, or other part) that one
stimulus alone doesn't produce or
generate.
Cont’d
Summation, also known as frequency summation
is the method of signal transduction between
neurons, which determines whether or not an
action potential will be triggered by the combined
effects of postsynaptic potentials.
Neurotransmitters emitting from the terminals of
a presynaptic neuron fall under one of two
categories.
Cont’d
• Signal transduction occurs when an extracellular
signaling molecule activates a specific receptor
located on the cell surface or inside the cell. In turn,
this receptor triggers a biochemical chain of events
inside the cell, creating a response. Depending on the
cell, the response alters the cell's metabolism, shape,
gene expression, or ability to divide. The signal can be
amplified at any step
Difference Between Spatial And Temporal
Summation
• Spatial summation is the additive effect of EPSPs or IPSPs
simultaneously originating from different presynaptic
neurons on the membrane potential of the postsynaptic
neuron. This involves multiple synapses that are active
simultaneously.
• The algebraic summation of potentials from different inputs
on the dendrites is considered in this summation.
Summation of EPSPs allows the potential to reach an action
potential, and summation of IPSPs prevents the cell from
achieving an action potential.
Cont’d
• Temporal summation is the additive effects of
sequential multiple EPSPs or IPSPs originating from a
single presynaptic neuron on the membrane potential
of the postsynaptic neuron.
• This involves single synapsis that is active repeatedly.
Temporal summation occurs when the time duration
is sufficiently long, and frequency of rises in potentials
are high enough to reach the action potential.
Cont’d
•Unlike the spatial summation, temporal
summation depends on the time duration of
which EPSPs occur, and the frequency of rises in
potential.
Cont’d
Spatial summation involves multiple synapses,
whereas temporal summation involves single
synapse.
In temporal summation, EPSPs occur rapidly one
after another while, in spatial summation, all the
ESPSs occur at the same time.
pictures illustrating the difference between
spatial and temporal summation
cont’d
cont’d

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