Phrenic Nerve Damage
Phrenic Nerve Damage
NERVE
DAMAGE
W H E R E I S P H R E N I C N E RV E ?
The phrenic nerve begins in the brain and then continues down to the
first few vertebrae of the spine, where it then splits. The two nerves then
continue through each side of the body, with the right side coming in
contact with the windpipe and heart, while passing the lungs. The left
side also comes in close contact with the heart, with both sides
eventually ending up in the diaphragm. Because of its location and
proximity to both the lungs and the heart, the nerve can be impacted if
there are specific conditions in either of these organs. If either of the
nerves is damaged and signals between the brain and diaphragm are
interrupted, normal breathing may be prevented.
C A U S E S O F P H R E N I C N E RV E
DAMAGE
Spinal cord injury: Depending on which vertebrae are damaged, nerve
impulses can be disrupted. It is more likely if the injury occurs above
the third vertebrae. If the injury is lower in the spine, breathing is
usually not impacted.
Physical trauma
- Neck injury, as related to above
Surgical complications or trauma
- Up to 10% of cases of phrenic nerve damage are caused by
operative trauma
- Because of its location, damage can unintentionally occur during
heart or abdominal surgery.
SIGNS AND
SYMPTOMS
Exertion dyspnea
Poor exercise tolerance
Chest pain
Cough
Hiccups
asymptomatic
DIAGNOSIS
Chest x-ray or sniff test
PFT
CT Scan
Chest radiograph
COMPLICATION
Diaphragmatic dysfunction following cardiac surgery
- Phrenic nerve injury commonly occurs from cold
cardioplegia or mechanical stretching during open-heart
surgery.
- Diaphragmatic dysfunction often occurs postoperatively
in patients undergoing cardiac surgery. This has been
attributed to pleurotomy in order to harvest internal
mammary artery (IMA) grafts, which results in greater chest
wall and parenchymal trauma, greater pain, and impairment
of cough and deep breathing. In addition, IMA dissection
may reduce blood supply to ipsilateral intercostal muscles
and may cause mechanical injury to the phrenic nerve.
MANAGEMENT
Those who are eligible may utilize the Avery
Breathing Pacemaker System, the only diaphragm
pacing system with full pre-market approval from
the USFDA and CE marking privileges under the
European Active Implantable Medical Device
Directive for both adult and pediatric use. It is
available for patients with an intact phrenic nerve.
The pacemaker may be used for patients with
phrenic nerve damage from the above causes, as
well as those suffering from CCHS, ALS, and
diaphragm paralysis.
THANK YOU