NERVE MUSCLE
1. Cell body or soma is also known as:
a) perikaryon
b) plasmalemma
c) Endokaryon
d) Neurofibrils.
2. Nissl granules are present in
a) Axon
b) Dendrite
c) Terminal button
d) Myelin sheath
3. The gaps between the Schwann cell is known as
a) axolemma
b) Node of ranvier
c) Oligodendrocyte
d) Mesaxon
4. The density of Na+ channels is maximum at
a) surface of myclin
b) soma
c) Nodes of ranvier
d) Dendrite
5. Rheobase denotes
a) specificity of impulse transmission
b) Rate of discharge of neuron
c) Strength of current
d) Duration of current
6. Action potential in nerve is all except
a) show all or none phenomenon
b) shows decremental response
c) can be summated
d) Required subthreshold stimulus
7. Magnitude of action potential of neuron is determined by
a) Na+
b) Mg+
c) Ca+
d) K+
8. Antidromic conduction can be seen at
a) synapse
b) soma
c) Axon
d) all of the above
9. Chronaxie
a) Of muscle is less than that of nerve
b) Indicates magnitude of stimulus
c) Denotes excitability of a tissue
d) Denotes conduction velocity of a tissue
10. Nerve fibre most susceptible to pressure is
a) Aα
b) Aβ
c) Aγ
d) C fibre
11. Pain sensation is carried by
a) Aα
b) Aβ
c) Aγ
d) Aδ
12. Type B fibre are most susceptible to
a) Hypoxia
b) pressure
c) Local anaesthesia
d) Temperature
13. Neurapraxia is a type of
a) Axonal disruption
b) Endoneurium disruption
c) Physiological conduction block
d) Nerve trunk discontinuation
14. The most excitable part of neuron is
a) Dendrites
b) soma
c) Intial segment of Axon
d) Axon terminal
15. The nerve fibre carrying sensation while has maximum diameter
a) Pain
b) propriouption
c) Temperature
d) Touch
16. Lambert-Eaton syndrome is due to
a) Auto antibodies formed against ach receptors
b) Autoanibodies against voltage gated ca2+ channels
c) Motor end plate folds on flattened
d) Decrease in Achrceptors on motor end plate
17. Which of the following is a depolarizing blocker?
a) Botulinum toxin
b) Carbamylcholine
c) Gallamine
d) Curare
18. Which of the following is a regulatory protein in skeletal muscle contraction
a) Titin
b) Actin
c) Nebulin
d) Tropomyosin
19. Which of the following is the largest protein?
a) Titin
b) Nebulin
c) Actin
d) Myomesin
20. Calcium binding protein in terminal cisternae is called as
a) Ryanodine receptor
b) Dihydropyridine receptor
c) calsequestrin
d) SERCA
21. Tropomyosin
a) helps in fusion of troponin and myosin
b) causes calcium release
c) slides over myosin
d) prevents attachment of actin and myosin
22. Conformational change in which myosin head bends on the hinge at an angle of 45® pulling the actin
filament towards the centre of sarcomere is known as
a) cross bridge formation
b) power stroke
c) Rigid state
d) Detached state
23. Stiffening of the muscle after death is due to
a) Depletion of ATP stores
b) Decrease in serum Ca2+ concentration
c) Increase in ATP stores
d) Increase in cytoplasmic Ca2+ concentration
24. Contraction of the muscle with no change in muscle length is known as
a) isometric contraction
b) isotonic contraction
c) iccentric contraction
d) concentric contraction
25. Twitch of single motor unit is called
a) Tremor
b) Fasciculation
c) Chorea
d) myoclonic jerk
26. Staircase phenomenon (Treppe) is due to
a) Tetanus
b) Summation of contraction
c) Progressive increase of calcium sarcoplasm
d) Increased troponin level
27. Immediate source of energy for muscle contraction is
a) ATP
b) Creatinine phosphate
c) Glucose
d) ADP
28. Reduced in the amount of dystrophin leads to
a) Duchenne muscular dystrophy
b)Becker Muscular dystrophy
c) metabohi myopathy
d) Myotonia
29. Sliding filament theory is proposed by
a) A.F.Huxley
b) Joseph Erlanger
c) Hebert S Gasser
d) Alan loyd Hodgkin
30. The number of motor end plate innervated by one motor neuron is
a)1
b) 2.5
c) 4-10
d) >10
31. The length of muscle at which maximum isometric active tension is called as
a) Initial length
b) Resting length
c) Maximum length
d) Active length
32. Most distinguishing difference between skeletal smooth muscle is
a) Tropomyosin
b) Myosin
c) Actin
d) Troponin
33. Gap junctions are present in
a) Type I skeletal muscle
b)Single unit smooth muscle
c) multi unit smooth muscle
d) Type II skeletal muscle
34. Lack of organized T-tubular system is seen in
a) Type I skeletal muscle
b) Type II skeletal muscle
c) smooth muscle
d) Cardiac muscle
35. Binding of calcium to calmodulin is due to dependence of
a) MLCK
b) MLCP
c) ATP
d) ADP
36. Property present in skeletal, smooth and cardiac muscle are
a) Duration of muscle twitch
b) Length – tension relationship
c) Phenomemar of fatigue
d) All or none-Phenomenon
37. Action of calmodulin is through
a) CAMP dependent kinase
b) calmodulin dependent kinase
c) CGMP dependent kinase
d) Magnesuim ATpase coactivation
38. Z line to the M line is connected by
a) Titin
b) Nebulin
c) Desmin
d) Alpha actinin
39. Average length of sarcomere is
a) 1µm
b) 2 µm
c) 3 µm
d) 4 µm
40. Initiation of action-potential occurs at?
a) Dendrites
b) Soma
c) Axon hillock
d) Axon terminal
