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601BP MC III July2023

This document is an examination paper for the B. Pharmacy course at Dr. Babasaheb Ambedkar Technological University, focusing on Medicinal Chemistry-III. It includes objective type questions, long answer questions, and short answer questions covering various topics such as anti-malarial agents, anthelmintics, antibiotics, and their mechanisms of action. The exam is scheduled for July 10, 2023, with a total of 75 marks available.

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omkaruse18062004
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5 views1 page

601BP MC III July2023

This document is an examination paper for the B. Pharmacy course at Dr. Babasaheb Ambedkar Technological University, focusing on Medicinal Chemistry-III. It includes objective type questions, long answer questions, and short answer questions covering various topics such as anti-malarial agents, anthelmintics, antibiotics, and their mechanisms of action. The exam is scheduled for July 10, 2023, with a total of 75 marks available.

Uploaded by

omkaruse18062004
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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DR.

BABASAHEB AVIBEDI(AR'fIiCHNOI,OGICAL UNIVERSITY,


LO
End Scmestcr Examination ;::,)
- Sulnmer- 2023
Course: B. Pharmacy Sem: \"'
6th
Subject Name: Medicinal Chemistrv-III Subject C
Max Marks: 75 Date:10/0712023 Duration: 3Hr

lnstructions:
l. All questions are compulsory
2. Draw diagrams / figures rvherever necessary
3" Figures to right indicate full marks

Q. 1. Obiective Type questions (Ansrver ali ihe questions) (10* 2) =29


i. Write the structure and uses of penicillin-G.
ii. Give the synthesis of lsoniazicl.
iii. List out important anti-vireil agents. Dr.aw the structure of acyclovir.
iv. Write the structure of any two anti-malarialdrugs.
v. what are antiprotozoal agents? \lrrite the structure ofmetronidazole.
vi. What are anthelmintics? Give exanrples.
vii. Give the structure and IUPAC name ofDtrpsone.
viii. Write the synthesis of para arnjno salicylic acid.
ix. Define anti-tubercular agents? Name the causative organism for tuberculosis.
x. Enlist the parameters of QSAR.

Q.2. Long Answers (Answer 2 out of 3) (2xlQ)=26


i. Define and Classify antimaiarial agents witir examples. Give the mechanism of action and
outline
the synthesis of chloroquine .

ii. What are anthelmintics'l Classify i.vith sLritable examples. Outline the synthesis and mechanisin
ol
action of Mebendazole.
iii. What are antibiotics? Classity u,ith exanrplcs Discuss the SAR & MOA o/tetracyclines

Q. 3, Short Ansrvers (Answer 7 out of 9) (7x5;=35


i" What are aminoglycosides? Write the mechanism and SAR of aminoglycoside antibiotics.
ii. Write a note on urinary tract anti-inf'ective agents.
iii. What are Sulphonamides? Explain thciL SAR.
iv. Write a note on combinatorial chemistry ancl its applications.
v. Define and classify anti-tubercular agents with examples. Write the MOA ofisoniazid.
vi" Add a note on synthetic antitungal agents. Give the synthesis of Tolnaftate.
vii. write a note on prodrug coucept and applications of prodlugs design.

-.----END OII THE PAPER--..--

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