Service Manual - ClearVue - A79210101
Service Manual - ClearVue - A79210101
© Copyright 2022. Epredia. All rights reserved. These instruments conform to the essential
requirements of:
Epredia makes every attempt to ensure that the information
contained in this supporting document is correct and clearly • In Vitro Diagnostic Directive 98/79/EC
stated but does not accept responsibility for any errors or
omissions. The development of Epredia products and services is
an ongoing process. Please ensure that any published information
Symbols
you use as a reference is up to date and relates to the condition
of the product. If necessary, check with your local Epredia The following symbols and conventions may be used
representative. throughout this document and on the instrument:
This document may not, in whole or in part, be copied,
This symbol is used on the equipment, or in a
photocopied, reproduced, translated, or converted to any
document, to indicate that instructions must
electronic or other form without prior written consent of Epredia.
be followed for safe and correct operation.
All information contained in this manual is proprietary and
confidential, and the exclusive property of Epredia and is This symbol is also used on the instrument, or
protected by copyright. in a document, to indicate that irritants or
potentially harmful chemicals are present.
Refer to the Material Safety Data Sheets for
the products, and always use Good
Laboratory Practice.
Shandon Diagnostics Limited, a subsidiary of Epredia This symbol is utilised on the instrument, or in
Tudor Road, Manor Park, Runcorn a document, to indicate that there are
Cheshire, WA7 1TA, UK potential biological risks associated with the
instrument and / or with instrument use.
Tel: +44 (0) 1928 534000 Always use Good Laboratory Practice.
Fax: +44 (0) 1928 534001
Web: www. epredia.com
Manufacturer
USA Distributor
Richard-Allan Scientific LLC, a subsidiary of Epredia
4481 Campus Drive A warning is given in the documentation if there is a
Kalamazoo, MI 49008, USA potential risk of injury, equipment failure or poor tissue
sample processing outcome.
Tel: 1-800-522-7270
Note
Fax: +1 269-372-2674
Web: www. epredia.com Notes give additional information about a job or
instruction, but do not form part of the instruction.
Contents
Company Information 3 Fit the Extraction Kit ....................................... 26
USA Distributor ................................................. 3 Change the Purge Tray and Debris Tray ......... 29
Start up the ClearVue ..................................... 30
Contents 4 Fill the Dispense Head Cleaning Station ......... 30
EMC Statement ................................................ 6 Degas the Mountant Bottle ............................. 32
Cleaning the Suction Cup ............................. 110 Appendix A3 – Parameters ........................... 245
Cleaning the Slip Dispense Carriage ............. 112 Appendix A4 – Accessories .......................... 247
Cleaning the Mountant Dispense Needle ...... 114 Appendix A5 – Spare Parts .......................... 248
Cleaning the Touch Screen........................... 115 Appendix B – Approved Reagents ............... 249
Cleaning the Slip Dispense Skirt ................... 115 Appendix C – Packing Instructions ............... 249
Cleaning the Gripper Return Plate................. 116 Appendix D1 – Main Menu ........................... 251
Cleaning the Slide Grippers .......................... 117 Appendix D2 – Mountant System Screens ... 252
Cleaning the Coverslip Transfer Head ........... 118 Appendix D3 – Options Screens................... 253
Cleaning the Camera .................................... 119 Appendix E – Understanding Log Files ......... 254
The battery manufacturers advise their customers to • The instrument contains no source
comply with the relevant regulations within their of ignition in any areas of the
particular country regarding disposal of this type of instrument where chemicals are
battery. stored or likely to leak in a single
The battery used within this instrument is: fault condition.
• The operator is fully aware of the
• 12 V 12Ah, valve regulated, sealed, lead acid
contents of the specification
type, rechargeable battery.
documents detailing the properties
This battery is classified as "Class 8 & Group III of the chemicals they are using.
UN No 2800 Batteries, wet, non-spillable, • The operator has carried out any
electric storage, special provision A67", and legally required assessment of
meets all requirements of the International Air chemicals used and is using good
Transport Association (I.A.T.A) Dangerous laboratory practice.
Goods Regulations.
• Some chemicals which may be
Batteries cannot be accessed by the used during operation are
customer and must only be replaced flammable - do not use sources of
by trained service personnel. ignition in the vicinity of the
instrument when it is loaded with
reagents.
Chemical Safety • Harmful chemical vapours such as
The introduction of chemicals creates potential Xylene and Toluene may be
hazards. Epredia has adopted the following position emitted during the normal
with regard to the subject of volatile chemicals used operation of some instruments
in laboratories: and the operator should be aware
of suitable precautions and safety
• The introduction of chemicals measures. The short term
creates potential hazards and exposure limits for Xylene and
Epredia has adopted the following Toluene will be no greater
position with regard to the subject 100ppm.
of volatile chemicals used in
medical laboratories:
• Non-specified chemicals are used
in the instrument at the customer’s
own risk.
The purpose of this Service Manual is to enable a • Ensure you employ normal standards of safety
qualified Epredia engineer to maintain the ClearVue and good laboratory practice. Think about your
in good condition. actions - always use common sense and the
best known practice when operating the
Safety instrument.
The Safety and Warranty Booklet (A79910001) and • If the ClearVue has been used with materials
the ClearVue Operator Guide (A79210100) should which are toxic or contaminated with pathogenic
both have been read and understood before using micro-organisms; follow the cleaning
this instrument. instructions given in Appendix C of the ClearVue
Operator Guide, and complete the Product
In addition, the following statements must be read Return Safety Certificate (See Safety and
and understood before commencing any work on Warranty Booklet) before servicing the
the ClearVue. instrument or returning the instrument to
• Potentially lethal voltages above 110Vac are Epredia.
present inside this instrument. Do not remove • Use only factory approved accessories or
any access covers unless trained to do so. replacement parts with the ClearVue.
Disconnect the instrument from the mains power • This instrument should be serviced annually by a
and switch the Battery Isolator Switch to the off Epredia trained engineer in accordance with the
’O’ position before carrying out any work on an instructions in this Service Manual.
area enclosed within an access panel.
• The ClearVue must be properly connected to a
good earth (ground) via the mains input supply.
All earth (ground) straps and connections must
be replaced correctly after service and before
switching the instrument on.
• Wear earthing (grounding) wrist straps and earth
(ground) yourself before handling connectors or
electronic components, as static electricity can
damage sensitive electronic parts. Damage from
static electricity can take weeks or months to
develop.
• The ClearVue is heavy and requires at least 2
people to lift it.
• As supplied, the ClearVue conforms to
IEC61010-1 and IEC61010-2-101; however the
addition of chemicals introduces potential
hazards. Follow good laboratory practice when
dealing with these chemicals, and be aware that
chemicals used with the ClearVue may be
flammable. Do not introduce sources of ignition
Pneumatic Circuit
The pneumatic circuit provides both positive
pressure and a vacuum. There are two pumps in the
circuit, both of which are capable of producing
either vacuum or pressure. The first pump connects
via the upper solenoid bank to the bottle and
provides either pressure for loading the syringe or
vacuum for the de-gas function. The second pump
is used for vacuum only and connects via the lower
solenoid bank to either the coverslip dispense
carriage or the coverslip transfer head. An extremely
sensitive exhaust is connected to the transfer head
solenoid; controlling the exhaust (decay) time is
critical to getting the correct mountant flow between
the coverslip and the slide.
• Most of the ClearVue electronics are contained • Link 6 is used to connect the on board battery to
within the electronics box. maintain the BIOS settings.
• This consists of the mains input power supply
Main Board
with 24VDC output; the main board connected
to the processor board via the interconnect The main board carries out several functions. The
board; the battery charger board and the power supply section generates the required
batteries (for battery backup in the event of a voltages from the 24V PSU input (or from the battery
mains failure). input). The processor board, which plugs into the
main board via the interconnect board, writes to and
• Some of the motors, solenoids and sensors
reads from the FPGA (field programmable gate
connect directly to the main board in the
array) which interfaces to the sensors and drives.
electronics box.
• In addition there are four other boards Power Supply
connected to the main board via ribbon cables.
The front interface board and back interface Conversion from the 24V input (from the power
board are used to connect to some motors, supply or battery backup) to:
sensors, etc.; the display interface board • 15V - used by the battery charger and by the fan
connects to the touch screen and some drive circuits.
sensors; the camera interface board had the
• 12V - used for the illumination LED’s on the
camera and illumination LED’s. camera board (switched on the main board).
Used by the display board for the screen
Mains inlet and power supply
backlight.
• The mains inlet in the side of the electronics box It also goes to the disk drive for drives requiring
has a double pole switch and two fuses (for the a 12V supply.
live and neutral lines). It also contains a mains
filter. • 5V for some of the logic and the sensors.
• The earth from the mains inlet connects directly • 3.3V for some of the logic.
to the primary earth stud in the electronics box. • 1.2V for the FPGA core power.
• The power supply has a wide AC input range. Note
The output is 24VDC. There is a power fail signal.
The 24V input from the power supply is fused (F1).
The power supply contains a cooling fan.
24V Switching
Processor Board
The 24V supply to the motors is switched on only
• The processor board runs the software to
when the processor is toggling the power watchdog
operate the instrument.
timer (via the I2C bus) and when the FPGA
• Flash memory on the board is used to store the
recognizes that the processor is active. This is used
software, parameters, logs, etc. for the motor drive circuits, the solenoid valves and
• The processor communicates directly with the the pumps.
FPGA on the main board.
• The processor uses an I2C serial Power Monitoring
communications protocol to communicate with I2C devices are used to monitor the power supplies.
various devices on the main board and on the These are read by the processor.
battery board.
LED Test Point Voltage • The FPGA controlled the signals to the motor
drive circuits under the control of the parameters
LED1 TP1 15V sent determined by the processor.
• The FPGA controls the DAC’s which provide the
LED2 TP2 24V – This is switched
reference signals to determine the current drives
on when the processor
and, where appropriate, micro stepping to the
and FPGA are OK
motors.
LED3 TP3 12V • The motor encoder signals are read by the FPGA
and used to derive the quad positions. These are
TP4 GND
used by the processor to monitor and control the
LED4 TP5 5V operation of the motors.
Note
LED5 TP6 3.3V
The cleaning station motor drive does not have
TP7 1.2V variable current capability or encoder feedback.
TP8 GND Camera Interface
The FPGA controls the data flow from the camera.
Note
It saves frames, parts of which are read by the
Take care if clipping probes to the test points. Avoid processor to determine gripper positions, slides in
applying stress. These are delicate surface mount baskets, etc.
test points and can easily be damaged (and may
LCD touch screen Interface
damage the board) if too much stress is applied.
More robust GND connections can be found on the The interface between the processor and the screen
motor drive IC heatsinks or on the ’D’ connector is on the main board.
screwlocks on the main board.
Links
Drives
• Directly below the LED’s on the edge of the PCB
The solenoid valves, air pumps, fan drives and
are the links. The 16- pin header takes 8
camera illumination LED drives are all from the main
removable links.
board. These are all switched by the FPGA under
• Links 1 to 6 are configuration links which are
the control of the processor.
read directly by the FPGA.
Opto and Door Switches
• Links 7 and 8 are used for configuring multiple
The slotted opto switches and the magnetically FPGA programming.
operated door switches are read directly by the • On ClearVue all 8 links must be fitted.
FPGA.
• In addition to the removable links there are 2
Coverslip Optos ’hard links’. These are fixed links on the PCB.
These are used to indicate specific board build
The reflective opto sensors used for the coverslip
standards.
detection feed into an ADC to be read by the FPGA.
They also feed the reference signals coming from a • The status of the removable links 1 to 6, and the
DAC, controlled by the FPGA, into comparators. two hard links, can be checked in the Production
The outputs from the comparators are used by the Services screens.
Compatibility
The ClearVue is compatible with the following sizes
of coverslips:
Downdraft
4 Access Door 10
Ventilation
Screwdriver and
View through the Access Door 19 Filter Cover 24
Allen Key
21 Rating Plate
Electrical Specifications
Voltage 100 - 240 V~
Frequency 50/ 60 Hz
System Interfacing
The Touch screen panel is the primary user interface Power (max) 300 VA
mode on the ClearVue. It is used to input data, Earth Leakage < 500 μA at 110-120 V~
operate the manual functions and inform the user of
instrument data. Fuses T 6.3 A, 250 V
In addition, the ClearVue will issue audible alerts Internal batteries Sealed Lead Acid type.
when appropriate. Not user replaceable.
General operation of the ClearVue is started by
~ denotes a.c.
opening and closing the Load door.
Temperature Temperature
(recommended (recommended
operation) operation)
• Daily Tasks
• Weekly Tasks
• Level the ClearVue before use
• Change the Carbon Filter
• Fit the Extraction Kit
• Maintaining the Xylene Tray Level
• Fill the Mountant Bottle
• Change the Purge Tray and Debris Tray
• Start up the ClearVue
• Fill the Dispense Head Cleaning Station
• De-gas the Mountant Bottle
• Flushing the System
• Purging the System
• Remove and Replace the Coverslip Hopper
• Shutting Down the ClearVue
• Load a Basket
• Unload a Basket
• Abort a Basket
• Manually Abort a Basket
• Remove Baskets from the Load & Unload Rail
• Remove Slides during Coverslipping
• Remove Baskets from the Vertical Lift
At daily Start up, lift the Coverslip Empty, clean and refill the Dispense
Hopper before switching on head cleaning station
Top-up the Dispense head cleaning Remove any discarded coverslips from
station. Wipe the top with a xylene damp the Slip Dispense area and clean the Slip
cloth dispense carriage
Check the number of Coverslips in the Remove the Coverslip transfer head to
hopper and replace if necessary check that the Pads and the Suction cup
are clean and free of Mountant. Wipe the
Check the level of Mountant and top-up Pads with a xylene damp cloth to clean
if necessary
Check the level of xylene in the Xylene
Wipe the Suction cup with a xylene Tray
damp cloth to ensure it is clean and free
from debris. Replace if necessary.
Empty the Debris tray
Ensure the Suction cup is dry before use
Notes
The Mountant Bottle supplies Mountant to the
After filling, de-gas the mountant bottle.
Dispense head. It is strongly advised not to allow the
Mountant bottle to run dry. If the Mountant Bottle has been allowed to run dry,
or the level has fallen below the bottom of the
To fill the Mountant bottle:
internal pipe, it will be necessary to:
• Remove the Mountant bottle cap.
1. Fill the Mountant Bottle.
2. De-gas the Mountant Bottle
3. Flush the system to remove any air from the
pipes
Note
Ensure coverslips are the correct size. Ensure
Coverslip Hopper has not been dropped by
checking for broken coverslips.
• Remove the empty Coverslip hopper by pulling • Remove the end cap from the bottom of the
slightly forwards and then lifting it gently Coverslip Hopper and retain for use as a Purge
upwards. Tray.
• Load the new Coverslip Hopper ensuring that
the Dispense Directional Arrow is pointing
towards the back of the instrument.
Note
If the Coverslip Hopper is not empty, use the end of
the paintbrush provided to push the foam inside the
Hopper down until it secures the remaining
coverslips.
• Unpack a new Coverslip hopper and identify the • Ensure the Coverslip retention spring is located
Dispense directional arrow on the top. inside the slot in the Hopper mounting block.
Note
Clear Count must always be selected after changing
the Coverslip size.
Notes
Ensure Slide Retainer is closed before loading
basket.
Ensure Directional Arrow on basket is pointing
upwards.
If operating outside of the recommended
temperature range, ensure samples do not dry out Keep the Basket upright after
too quickly by loading no more than 2 Baskets at unloading - Basket Rack is supplied
any one time. for this purpose.
Unload a Basket
To unload a Basket:
• From the Basket abort screen press the Abort Any Baskets which are unloaded
key. manually may contain slides which
have not been coverslipped, and
steps should be taken to preserve the
specimens.
Note
The ClearVue will finish coverslipping the current
slide before it aborts the basket.
Notes
The right-hand Gripper jaw is spring loaded and can
be moved to the right to release the slide.
It is advisable to remove the Debris Tray and then
reach into the instrument through the Debris Tray
Door in order to support the Slide when removing it • The Screwdriver should slot into the Vertical Lift
from the Gripper jaws. lead-screw.
• Reach in through the Load Door and pull the • Turn the Screwdriver clockwise to raise the
long Gripper jaw as far towards the left of the Basket until it is level with the Unload Rail.
instrument as possible.
Note
Remove Baskets from Vertical Do not turn the Screwdriver anti-clockwise once the
Slides are above the Slide Guide as this could result
Lift in broken Slides.
To remove baskets from the vertical lift: • Close the Slide Retainer as soon as possible to
• Open the Unload Door. ensure that no Slides fall out of the Basket.
• Once the Basket is aligned with the Unload Rail,
pull the Basket onto the Unload Rail and remove
as normal.
If the Gripper jaws and Basket Unload
Bracket are not correctly located as
described above, any attempt to raise
the Basket may lead to damage to
the instrument, Basket or specimens
I/O
• From the Option menu press Disc.
This tab shows Sensor Inputs, Switch System
Outputs (eg: pumps / solenoids) and information on
Voltages and Battery Backup Status.
MOTOR
Note
It is advisable to output the current parameter
settings to disk before attempting to adjust
parameters – refer to the Eng Tab – Page 3/7
section.
Note
If the state of any pumps or solenoids are changed,
a full initialise must be carried out prior to using the
machine.
Refer to the Pneumatics Diagrams section for the
pneumatics diagram.
• This screen shows the door sensors and the filter • Mountant pump sol is the solenoid between the
syringe and the mountant bottle or dispense
switch.
needle.
• For the doors, a ’0’ indicates door open, a ’1’
• 0 = syringe to dispense needle. 1 = syringe to
indicates door closed.
mountant bottle
• For the filter switch, a ’0’ indicates filter present,
• Prep solenoid 1 is the coverslip dispense
a ’1’ indicates filter not present.
carriage solenoid.
• 1 = Vacuum to coverslip dispense carriage (Prep
sol 2 must be 0)
• Prep Solenoid 2 is the support arm suction cup.
• 1 = Vacuum to the suction cup (Prep sol 2 must
be 0)
• Bottle Solenoid 1 is the mountant bottle vacuum
solenoid. See table below for settings.
• This screen shows the speeds of the two fans. • Bottle Solenoid 2 is the mountant bottle pressure
• To exit the current screen and return to the I/O solenoid. See table below for settings.
screen, touch the 'Exit' key. • Bottle Pump is the vacuum pump for the
mountant bottle.
I/O Tab - OUTPUTS • Prep Pump is the vacuum pump for the coverslip
Pressing the OUTPUTS button displays the dispense carriage and suction cup.
following screen:
Prep Solenoid
Status
1 2
No vacuum on carriage or
suction cup (pump has
0 0
nowhere to pull air from; puts
strain on the system).
Over Charge 1 1
Float Charge 0 0
Note
These are only displayed correctly when the battery
board is issue 2 or above (HL2 = ’0’).
There are no features to edit or change in this page, • Press the screen in any location to return to the
this just shows the status of some of the I2C bus previous menu.
signals (mainly from the battery board).
Note Column 1
When in power fail mode, Batt2 voltage will be both Identity on Location Comments
Batt1 + Batt2 values added together and shows the Screen
voltage available to the coverslipper when no mains
is present. MB Main Board, Link 1 Accesses via
FPGA
This will be shown when baskets are being BASK OPEN - Basket slider open
coverslipped. EJECT - Basket eject motor
Initialising SLIP DISP - Coverslip dispense motor
This will be shown when the coverslipper is GRIPPERS - Slide gripping motor
initialising.
M_PUMP - Mountant pump motor
Mountant
N_POT - Cleaning station motor
This will be shown when the user is in the mountant
• The box below this indicates the motors' current
menu pages.
Quadrature reading and expected position. In
most cases the position should match the quad.
A variation between these two values will
indicate a stalling motor or the axis has reached
Note
Some of the keys on these pages may change
depending on the latest version of the software.
• ENG Tab - Page 1/7
• ENG Tab - Page 2/7
• ENG Tab - Page 3/7
• ENG Tab - Page 4/7
• ENG Tab - Page 5/7
• ENG Tab - Page 6/7
• ENG Tab - Page 7/7
• Prepare a basket of 20 dry slides and then select • Put "Prep" back to "1"
/ do the following:
• Prepare a basket of 20 dry slides, ensure a good This is a factory test. Do not run this test unless
hopper with adequate quantity and quality of specifically requested to do so by the factory or
coverslip is in place and then select / do the unless directed to do so from within this manual.
following:
Do not enter this menu unless you
• Load the basket of dry slides have been specifically instructed to do
• A coverslip will be dispensed and will pause by so. If you do enter by mistake with the
the coverslip transfer head wrong software version the machine
• The rear edge of the coverslip should be aligned will need to be switched off by the
with the rear edge of the coverslip transfer head battery which will lose any changes
made to setting and may corrupt the
• If the coverslip is correctly aligned press accept
machines files
• If it is not aligned use the up or down arrows to
move the next coverslip in the direction required Results
Note First asks for the serial number of the ClearVue then
copies the results to a floppy disk.
1 increment = 0.181 mm
• This will not alter the current coverslip position,
but will change the relationship for the next
coverslip dispensed.
• Press next
• The coverslip will be transferred to the slide and
pause
• The coverslip should be aligned centrally to the
slide (left to right)
• If the coverslip is correctly aligned press accept
• If it is not aligned use the left or right arrows to
move the next coverslip in the direction required
Pnumat 3
Shows a screen for testing coverslip dispense. OPTIC 1 and OPTIC 2 - Current value being read
from the slip dispense optos (in realtime). Lower
readings indicate a slip (typically 200-600). Each
optic floats around the value 1300 to 1400 with no
slip.
LOGIC 1 and LOGIC 2 - Logic values of slip
detected during dispense, 0 = detected slip 1= no
slip.
The testslip page has two main functions. Latch -not used.
1. To check the coverslip dispense mechanism is QC Pass - 1 = good slip. 0 = slip properties failed
performing correctly. criteria.
2. To check the optic 1 and 2 coverslip sensors Q and P -Current slip dispense motor quad and
are working correctly. position values.
Buttons and actions:
Beads
SLIP OUT - Dispenses a coverslip from the hopper.
Beads key.
RETURN - Returns the carriage back to the
• Toggles between '0' and '1'. The value shown
coverslip pickup position.
on the key is its current state.
INIT - Performs an initialization on the coverslip • When set to '0', it operates normally.
dispense carriage.
• When set to '1' a bead of mountant is dispensed
HALF OUT - Dispenses a coverslip half way out so onto the slide but no coverslip is used.
that the glass is under the optos for opto calibration • This can only toggle when the machine is idle.
and adjustment.
• This is reset to '0' during a full initialise.
EXIT - Exit from the current screen.
Note
ENG Tab - Page 3/7
ClearVue will not function correctly until Production
Tests 5 and 6, and Autoslip have been carried out
correctly.
exit2dos
i-lift
Notes
Do not perform an initialization while there is a
basket on the lift block.
The lift can clash with the load rail and eject bracket;
ensure all assemblies are clear before pressing 'init'.
i-npot
Note
The Dispense head cleaning station can clash with
the dispense head; ensure all assemblies are clear
before pressing 'init'.
i-slip
Note
The slip dispense and mountant dispense head can
clash with the dispense head cleaning station, slide
grippers and coverslip transfer head. Ensure all
assemblies are clear before pressing 'init'.
i_pump
i_camera
Note
Notes
This may give an incorrect gripper position if the
The 'cam focus clean’ value is an indication of any
grippers have been moved since last gripper
blurring of the image. A value of 5 or more may
initialization.
indicate that the lens needs cleaning.
TFT BLIT
'Cam status bits' are: Link 5, Camera type, Camera
This causes every image from the camera to be Ready, Digital mode. These are only valid after the
displayed on the screen. camera has been initialised and are for Engineering
Pressing the key again switches this function off. use only.
Beadopt
The machine will initialise when this menu is exited 'OFFSET' switches the position between end and
to the home screen. middle.
• Flush
5minmode
This function temporarily disables all the safety There is a risk of static shock when
interlocks on ClearVue and should only be used by performing this test - Ensure the
trained personnel. ClearVue should never be left debris tray is suitably earthed before
unattended whilst in '5Minmode'. commencing test.
• Basket Eject Motor Test • Press one of the 'left arrow' keys - check that the
transfer head moves to the left (anti-clockwise)
• Coverslip Dispense Motor Test
and that the QUAD and POSITION values
• Gripper Motor Test
increase.
• Mountant Pump Motor Test • Press one of the 'right arrow' keys - check that
• Dispense Head Cleaning Station Motor Test the transfer head moves to the right (clockwise)
and that the QUAD and POSITION values
Input Rail Motor Test decrease.
• From the TAKE CONTROL screen scroll to the • Take care not to stall the motor by hitting the
LOAD motor screen. head position pin on the lower crank arm when
• Press 'Set' and check that the QUAD and rotating to the right (clockwise). The pin can be
POSITION values are set to 10000 and are not damaged.
changing. • When rotating left (anti-clockwise) ensure that
• Set the power to 64 (maximum). the mechanism does not hit the mountant
dispense arm or the grippers.
• Press one of the 'right arrow' keys - check that
the load rail mechanism moves to the right and
that the QUAD and POSITION values increase.
• Press one of the 'left arrow' keys - check that the
load rail mechanism moves to the left and that
the QUAD and POSITION values decrease.
• Press one of the 'down arrow' keys - check that • This motor runs at fixed power - changing the
mountant pump mechanism moves downwards power setting has no effect.
and that the QUAD and POSITION values • Press one of the 'up arrow' keys - check that
increase. cleaning station mechanism moves upwards
• Press one of the 'up arrow' keys - check that the and that the QUAD and POSITION values
mountant pump mechanism moves upwards increase.
and that the QUAD and POSITION values • Press one of the 'down arrow' keys - check that
decrease. the cleaning station mechanism moves
• The movement can only be seen if the covers are downwards and that the QUAD and POSITION
removed. values decrease.
• If the covers are fitted, the same test can be • When moving the cleaning station in an upwards
carried out to check that the QUAD and direction, ensure that it will not hit the mountant
POSITION counts change correctly, however to dispense needle - damage may occur.
verify that mountant is being dispensed, using • After the test has been carried out, the cleaning
the I/O tab, OUTPUTS (Refer to the I/O Tab – station (filled with xylene) should be moved back
Outputs section) set the 'Mountant pump sol' to into position to prevent the mountant in the
'1', next lower the cleaning station then move the dispense needle from drying out. This is most
coverslip dispense mechanism to place the easily carried out by going to the production
mountant dispense needle above the purge tray. services, (Refer to the ENG Tab – Page 4/7
Now, at the M_PUMP motor screen use one of section) and pressing the 'i-slip' key to initialise
the 'down arrow' keys and observe the the coverslip dispense system (including the
mountant being dispensed out of the needle. cleaning station).
• To refill the syringe set the 'Mountant pump sol'
to '0' and drive the dispense mechanism
upwards.
• Once finished, initialise the coverslip dispense
mechanism using 'i-slip' (Refer to the ENG Tab
– Page 4/7 section), to ensure that the needle is
left in the cleaning station to prevent the
mountant from drying out.
During this stage the speaker connection is • When the unload door is opened the speed
checked, all of the motors and opto switches are should increase to greater than 80Hz.
used and the camera illumination is also checked. • Go to the I/O Tab, I2C screen (Refer to the I/O
Tab – I2C section).
• With the prep door open, switch the machine on.
• Check that PFD shows '0', PWR_WDT shows
• The speaker should bleep and the internal
'0', pw state shows '0100' and WGO shows '0'.
illumination should be off.
• Check that B-SW shows '1' when the battery
• Close the prep door.
switch is on and that this is '0' when off.
• The speaker should stop bleeping and the
• Make sure that the battery switch is on.
internal illumination should come on.
• Switch the mains off.
• Allow initialise to finish.
• Check that PFD shows '1', PWR_WDT shows
• Check, on the main menu, that the 'Status' is
'0', pw state shows '0110' and WGO shows '1'.
'OK'.
Note
Stage 2 - Production Services
These signals must be checked immediately after
During this stage the doors and filter switch are switching the mains supply off.
checked, the fans are checked, the battery backup
The PFD and WGO signals are only valid for
system is checked, the voltage regulators are
approximately 5 seconds after which their states are
checked, the links on the PCB's are checked, the
indeterminate and either of them may show '1' or
slip dispense opto's are checked and the camera
'0'.
operation is checked.
• Switch the mains back on, check that the signals
• Go to the production services screens (Refer to
return to the correct state. It may take a few
the I/O Tab section).
seconds for 'pw state' to change from '0110'
• Go to the I/O Tab, INPUTS screen (Refer to the back to '0100'.
I/O Tab – Inputs section).
Signal Mains On Mains Off
• Scroll through to the screen with the doors.
• Check each door in turn. The screen should PFD 0 1*
show '0' for door open, '1' for door closed.
PWR_WDT 0 0
Note
pw state 0100 0110
When the load door is closed, the load rail system
should check for a basket. WGO 0 1*
• Check that when the filter is in place the screen
• Go to the I/O Tab, VOLTAGES screen (Refer to
shows '0'.
the I/O Tab – Voltages section).
• Check that when the filter is removed the screen
• Check that the voltages (and temperature) are in
shows '1'.
the following ranges:
• Scroll through to the screen with the fans.
• Check that the electronics fan feedback signal is
greater than 80Hz.
Note
The battery voltages are dependant on the charge state.
• Batt2 voltage will show Batt1+Batt2 (nominal 24V) during mains power fail.
• With the battery switch in the on position, switch the mains off. Check that Batt2 changes to at least 20V.
• Switch the mains back on and check that Batt2 returns to a normal reading.
• Go to the I/O Tab, LINKS screen (Refer to the I/O Tab – Links section).
• Check that the links are as shown:
• Insert a hopper of coverslips. • Check that ball spring plunger moves freely.
• With no coverslip under the sensors, check that • Check the pop out pin moves freely.
the 'Optic 1' and 'Optic 2' readings are between • Check the drive nut is screwed fully into the latch
01200 and 01500 and that 'Logic 1' and 'Logic carrier.
2' are both '1'. • Ensure neither latch is loose on the latch carrier.
• Press HALF OUT. Check that a coverslip is • Ensure the motor and leadscrew turn freely
under the sensors. Check that the 'Optic 1' and without tight spots for the full travel.
'Optic 2' readings are between 200 and 1000
• Ensure there is no radial play in the bearings at
and that 'Logic 1' and 'Logic 2' are both '0'.
either end of the leadscrew.
• Press RETURN. Check that the slip is cleared.
• Check the belt tension; refer to the Input Motor
• Press SLIP OUT. Check that a 'Good slip' is Assembly section.
indicated.
• Power on the ClearVue and test the motor
• Go to the ENG Tab, Page 5/7 (Refer to the ENG function, refer to the Input Rail Motor Test
Tab – Page 5/7 section). section.
• Select 'snapshot'. • Go to screen 1 on the inputs page of production
• Check that the image is square and that the services, turn the motor manually and ensure
gripper jaw is positioned in the right hand side of that the 'load home' opto changes state as the
the screen. latch carrier passes through it.
Disk Drive Check Inspecting the Vertical Lift and Lift Block
During this stage the connections to the disk drive • Ensure that the unit is powered down.
are checked. • Check for any mountant build up and clean if
• Insert a floppy disk into the disk drive. required.
• Write an engineer’s log to the disk. • Check for any glass or basket debris and clean
if required.
• Move the disk to a PC. Check the files on the
disk have been written correctly. • Check none of the pins are bent.
• Open the log and check for corrupt characters, • Check that the spring plunger moves freely.
etc. in the engineer’s log. • Ensure the motor and leadscrew turn freely
without tight spots for the full travel. With the
Performance Test motor disconnected from the front I/F board the
During this stage the operation of all of the solenoids motor should travel from top to bottom with less
(including the mountant dispense) are checked and than 0.1Nm or torque.
the pressure sensors are checked. • Ensure there is no radial play in the bearings at
either end of the leadscrew.
Run performance test 1 (Refer to the Performance
Test 1 section). • Check the end float in the leadscrew is greater
than 0.05mm and less than 0.1mm.
Inspecting the Cleaning Station Assembly Inspecting the Mountant Bottle and Lines
• Ensure that the unit is powered down. • Remove the covers.
• Check for any dried mountant build up and clean • Check for any air in the lines or syringe.
if required. • Remove the mountant dispense needle
• Check for any glass or basket debris and clean assembly from the support arm.
if required. • Place mountant dispense needle over a
• Check the condition of the pot seal and replace container to collect the mountant and Xylene
if required. waste (Gemini pots are a good size and shape
for this).
• Empty the pot and check inside for any dried
mountant. Do the following, looking for where any air enters the
system.
• Check that the pot locates easily onto stub shaft.
11/20/2007 08:08:59 Good slip dispensed with latch optics at 00227, 00210 6
Note
The shaded section at the end of each line has been added as a point of reference for this manual.
It will NOT be shown on an actual engineer’s log.
• The date is shown in the format MM/DD/YYYY and the time is in hh:mm:ss.
• When the correct time and date have been located, look for 'Slide No: 01' (see end of Line 1) which is the
first slide in a basket.
• Then locate the corresponding 'Prep Decay Time' (see Line 9) for the slide.
• The time should be between 2 and 4 seconds.
• Repeat this for all 20 slides (Slide No: 01 to Slide No: 20) and ensure they are all within the correct range.
Anything with a Prep Decay Time of < 1.5s will result in a large number of bubbles and unacceptable Prep
Quality!
Note
Ensure the large hole in the bracket fits over the
boss on the support arm.
• Fix the gauge plate to the short gripper arm as
shown using the cap-head screw provided
Note
The tip of the long gripper jaw must be lower than
the tip of the short gripper jaw (to within tolerance).
• Position the DTI probe on the upper surface of
the long gripper jaw and manually move the jaw
to determine the run-out.
The tip-to-tail variation must be within 0.2mm.
Note
Do not over tighten the needle locking screw as
customers need to be able to remove the needle
without tools.
Note
The large portion of the cam should be orientated
upwards as shown in the diagram below.
• Re-tighten the lock nut ensuring that the short
gripper does not move in the process.
• Check cam setting to ensure it is still correct.
Note
The mountant will run while it is still liquid, so ensure
the slides are kept flat at all times.
• Refer to the Excessive Bubbles section for
details on interpreting Bead Test results.
Advanced Bead Test
The 40mm Coverslips can be positioned centrally, • Move the Coverslip transfer head into the
and also offset by 5mm when using the Offset position specified.
coverslip transfer head. • Press OK on the Position Setup screen.
Note
When using the Offset coverslip transfer head with
40mm Coverslips, the ClearVue automatically
places the Coverslip on the slide in the correct
position, regardless of whether the End or Centre
position has been selected.
Note
An Engineers’ log can only be written when the
ClearVue is idle (not processing baskets). An audible
warning sounds if you attempt to write an
Engineers’ log during processing. • The ClearVue will then automatically install the
updated software and reboot itself.
Update the System Software
Do not switch off or interrupt the
Do not perform a software update power during this process
unless instructed to do so by a
Epredia Service Engineer. • The new software will be active when the reboot
The Disc Options screen allows the ClearVue is complete.
software to be updated. A Software Update would
normally be performed by a Service Engineer;
however, it is possible for the user to perform an
update if supplied with a new version on a floppy
disc.
Note
If there is very little variation in the thicknesses of
samples, the volume of Mountant dispensed for
Baskets with either a black or a white Slide Retainer
can be set to the same value.
Note
Settings will automatically adjust to suit the
Coverslip length, so that the same Mountant Setting
dispenses a larger volume of Mountant for a 50mm
Coverslip than for a 40mm Coverslip.
• Fit the Offset coverslip transfer head: D. Insert the other end of the pipe into the connector
of the Rotatable fitting on the ClearVue.
Note
When the Offset coverslip transfer head is fitted, the
ClearVue automatically places the 40mm coverslip
A. Fit the Offset head onto the Location pins.
on the slide in the correct position.
• Replacing seals
• Removing the mountant bottle In the event of a major spillage on or
around the ClearVue, immediately
• Preparing the ClearVue for storage
disconnect the instrument from the
Mains supply, and do not reconnect
until the instrument has been
Cleaning and Maintenance thoroughly dried and check by a
Precautions Epredia Service Engineer.
For Daily tasks refer to the Daily Tasks section. Potentially lethal voltages in excess of
110V a.c. are present within the
For Weekly tasks refer to the Weekly Tasks section.
ClearVue - Do not remove any access
If the ClearVue has been used with, or covers.
has come into contact with, hazardous
material, ensure that the appropriate Disconnect the ClearVue from the
decontamination procedures have Mains before cleaning.
been followed (See World Health
Inspect the instrument for obvious
Organization 'Laboratory Biosafety
damage or wear whenever it is being
Manual').
cleaned.
Cleaning or decontamination methods,
other than those recommended in this
document, should be checked with a
Epredia agent to ensure that they will
not damage the instrument.
• Wait for activity within the ClearVue to stop, and • Use a xylene damp cloth to clean all the surfaces
Access Ready to flash. of the cleaning station including the top of the
internal parts.
• Refill to about ¾ full with xylene.
• Reassemble the cleaning station and refit into
the ClearVue.
Note the position of the Coverslip transfer head and • Ensure the suction cup protrudes from the base
then remove it from the Location pins. of the coverslip transfer head.
Dispense Needle
Take precautions when dealing with
Xylene!
After cleaning:
• Flush the system
• Unscrew the Mountant dispense needle
assembly and lift it out of the Support arm. Ensure the Dispense head cleaning
station is topped up
Note
Note
Cleaning the camera is Not a routine maintenance
Pull firmly on the Pneumatic pipe to check that it is
task, and should only be done if advised by a
correctly fitted into the Pneumatic connectors.
Epredia Service Engineer.
Region Telephone
164 Head position wrong, tested on init and just before basket open
13
167 Head position wrong just before taking basket up lift
During power failure recovery, the input door is opened suggesting further baskets
18 20
are to be loaded
26 94 Slide too wide alarm. User will be alerted at the end of basket processing
Do the following:
• Check that the coverslip transfer head hard-stop
Coverslip placement not
is clean.
controlled - coverslip is
dropped quickly into the • Coverslip transfer head should not have tight-
mountant and xylene. spots when rotated (refer to the Inspecting the
Coverslip Transfer Head section).
• Check, and adjust if necessary, the coverslip
Multiple bubbles visible at transfer head sprung pads (refer the Checking
non-frosted end of slide and Adjusting the Coverslip Transfer Head
Sprung Pads section).
• Check, and adjust if necessary, the coverslip
transfer head hard-stop (refer to the Checking
and Adjusting the Coverslip Transfer Head Hard
Stop section).
• Re-initialise the coverslip transfer head (refer to
the ENG Tab – Page 4/7 section) and watch the
preparation of a cleared slide.
Standard coverslip
transfer head and offset Check, and adjust if necessary, the coverslip
coverslip transfer head transfer head hardstop (refer to the Checking and
swapped without hard- Adjusting the Coverslip Transfer Head Hard Stop
stop being adjusted to section).
suit.
Offset coverslip transfer Use only 40mm coverslips, or replace the offset
head used with incorrect coverslip transfer head with original (black or silver
size coverslip coloured)
Air in Pipes or Syringe Flush system to ensure bubbles have been expelled
Coverslip placement not • Compare with the customers decay time found in the
• Often down one side controlled - coverslip is Log file (refer to the Engineer’s Log Extraction section).
of slide dropped quickly into the • Remove the suction cup and check that the profile of
• Various sizes of mountant and xylene. the lip is flat, even and undamaged.
bubbles
• Replace the suction cup if necessary (refer to the
Software Update section).
Do the following:
Coverslip placement not • Check that the coverslip transfer head hard-stop is
controlled - coverslip is clean.
dropped quickly into the • Coverslip transfer head should not have tight-spots
Single bubble at Non-
mountant and xylene. when rotated (refer to the Inspecting the Coverslip
frosted end of slide
Transfer Head section).
Mountant not flowing on Check mountant type against approved reagent list.
slide correctly (thick
mountant). Check temperature of lab is >17°C.
Dispense Head too high Check Dispense Head is fully screwed down
Offset Coverslip Transfer Use only 40mm coverslips, or replace the Offset
Head used with incorrect Transfer Head with the original one (black or silver
size coverslip coloured)
Coverslip contacting
Carry out Production Test 6 and check the position of
mountant too soon, while at
coverslip pick-up.
high speed.
Mountant not flowing on Check mountant type against approved reagent list.
slide correctly (thick
mountant). Check temperature of lab is >17°C.
Offset Coverslip Transfer Use only 40mm coverslips, or replace the Offset
Head used with incorrect Transfer Head with the original one (black or silver
size coverslip coloured)
Contamination from
Clean the instrument, ensuring all broken glass and dried
debris within the
mountant is removed.
instrument.
Thick or uneven
specimen causing
Check quality of specimen being coverslipped.
coverslip to lift off the
slide.
Debris under the Ensure coverslips are free from debris and dust
coverslip Ensure Slip Dispense Area is free of debris and dust
Strip of no mountant
• A distinct line of
coverslip is not stuck to
slide
Mountant dispense Check slides are held securely in the gripper jaws (refer
needle height changes to the Inspecting the Slide Grippers section).
intermittently due to slide
moving in gripper jaws.
Wrong version of profile Confirm that the pump profile version is correct (refer to
with incorrect suckback. the Checking Software, FPGA and Pump Profile Version
section).
Old mountant which has • Confirm the age and history of the mountant and the
been left for a long usage of the instrument.
period, or with no lid,
allowing the viscosity and • If in doubt, flush the system with xylene twice, then
characteristics to replace mountant with fresh from an unopened bottle
change. and flush through the system.
Unapproved mountant
with an extreme of
Check mountant against Approved Reagent List.
viscosity or characteristic
which is not compatible.
Inappropriate mountant
volume dispensed onto Check mountant volume setting (default is 13).
the slide.
Unapproved mountant
with an extreme of
Check mountant against Approved Reagent List.
viscosity or characteristic
which is not compatible.
Mountant dispense
needle height changes Check slides are held securely in the gripper jaws (refer
intermittently due to slide to the Inspecting the Slide Grippers section).
moving in gripper jaws.
Mountant dispense
needle too high from Check, and adjust if necessary, the dispense needle
slide, allowing mountant height (refer to the Checking and Adjusting the Needle
to form a drop before Height section).
contacting the slide.
Contaminated Mountant
• Flush the system with Xylene
(via thinning)
• Refill the Mountant bottle and Flush through the
system
Instrument is still
carrying out initial • Wait 30 seconds for the initial tests to finish.
tests.
• Check the wiring from the power supply to the main board.
Check that the LEDs on the edge of the main board are on,
indicating that the following voltages are present (top to bottom):
• 15 V
• 24 V
• 12 V
• VCC (5 V)
Other power faults. • 3.3 V
Notes
The 24 V indicator LED will only be lit once the system has booted
and is running normally.
If the 15 V, 12 V, VCC or 3.3 Vindicator LEDs are not lit, replace
the main board (refer to the Main PCB, Interconnect PCB and
Processor PCB section).
If the 15 V, 12 V, VCC and 3.3 V indicator LEDs are lit, but the 24
V indicator LED fails to come on after approximately 30 seconds,
carry out the following sequence:
Processor fault. • Check that the interconnect board is correctly mated with the
processor board and with the main board.
Instrument in
Standby mode; Touch the screen to switch instrument out of Standby mode.
screensaver ON.
If the 15 V, 12 V, VCC and 3.3 V indicator LEDs are lit, but the 24
V indicator LED fails to come on after approximately 30 seconds,
carry out the following sequence:
• Check that the interconnect board is correctly mated with the
Processor fault. processor board and with the main board.
ClearVue is
• Replace the processor board.
powered ON but
the screen is If the 15 V, 12 V, VCC and 3.3 V indicator LEDs are lit, and the 24
blank. V indicator LED comes on after approximately 30 seconds, carry
out the following sequence:
• Check the ribbon cable from the main board to the display
board.
Display fault. • Remove the instrument covers and check the flex cable
between the display board and the display.
Dispense head Mountant build-up on Remove and clean the dispense head (refer to the Cleaning the
dirty. dispense head. Dispense Head Cleaning Station section).
Place a spirit level on the output rail and adjust the feet to level the
Instrument not level.
instrument (see Instrument Levelling Instructions).
Gripper return plate is Remove and clean the gripper return plate (refer to the Cleaning
stuck the Gripper Return Plate section).
Check the required coverslip position with the customer and then
40mm coverslip ensure that the coverslip transfer head is correctly positioned
position set (refer to the Change the Coverslip Transfer Head Position section).
incorrectly. Ensure the software and transfer head position are consistent
(refer to the Select the Coverslip Position section).
Coverslip Wrong size of Ensure approved coverslips are used (refer to the Compatibility
position wrong coverslip or slide. section).
on slide.
Set coverslip position to 0 (refer to the Adjust the Coverslip
Machine settings
Position section).
have changed due to
new or refitted parts. Run Production Test 6 to set the coverslip position.
Replace and set the gripper jaws (refer to the Checking and
Worn gripper jaws.
Adjusting Gripper to Gripper Alignment section).
Mountant volume Check that mountant volume setting is between 10 and 15 (refer
set too high. to the Adjust the Mountant Dispense Volume section).
Coverslip position is
Ensure there is a 2mm gap between the coverslip and the end of
too close to the side
the slide, and that the coverslip sits centrally.
/ end of the slide.
Place a spirit level on the output rail and adjust the feet to level the
Mountant Instrument not level.
instrument (see Instrument Levelling Instructions).
overspill
Suction cup sitting
too low on the Ensure suction cup is fitted correctly (refer to the Cleaning the
coverslip transfer Suction Cup section).
head.
Insufficient volume Check that mountant volume setting is between 10 and 15 (refer
of mountant to the Adjust the Mountant Dispense Volume section).
Very thick specimen Increase the mountant volume (refer to the Adjust the Mountant
under the coverslip. Dispense Volume section).
Mountant dryback
Check that the stainer is set up correctly and allows sufficient
Poor clearing
clearing.
Incorrect clearing Ensure that the stainer is using the recommended clearing
agent used. agents.
Incorrect mountant
Only use recommended mountant.
used.
Chipped or broken slide Ensure only undamaged slides are loaded onto the
loaded into basket. instrument.
Gripper return plate stuck or Remove and clean gripper return plate (refer to the
fitted incorrectly. Cleaning the Gripper Return Plate section).
Paint on long gripper Replace long gripper jaw (refer to the Gripper Jaws
damaged. section).
Bent basket unload bracket. Inspect unload bracket and replace if necessary.
Coverslip Mis-Dispense
Problem Cause Solution
Loss of vacuum on suction Clean suction cup and replace if necessary (refer to the
cup. Cleaning the Suction Cup section).
Carriage vacuum ports Clean the vacuum ports (refer to the Cleaning the Slip
blocked. Dispense Carriage section).
Coverslip dispense skirt Clean coverslip dispense skirt (refer to the Cleaning the
needs cleaning. Slip Dispense Skirt section).
Optical sensors need Reset the optical sensors and run 'Autoslip' (refer to the
adjusting. ENG Tab – Page 6/7 section).
Mountant or debris on
Clean suction cup.
suction cup.
Loss of vacuum on suction Clean suction cup and replace if necessary (refer to the
cup. Cleaning the Suction Cup section).
Carriage vacuum ports Clean the vacuum ports (refer to the Cleaning the Slip
blocked. Dispense Carriage section).
Coverslip dispense skirt Clean coverslip dispense skirt (refer to the Cleaning the
needs cleaning. Slip Dispense Skirt section).
Coverslip dispense skirt • Clean coverslip dispense skirt and support plate.
unable to move freely in its
slot. • Check for screws protruding through plate or excess
threadlock on sliding faces.
Basket slider not fully closed. Ensure slider is fully closed prior to loading basket.
Faulty vertical lift leading to lift Inspect vertical lift (refer to the Lift Block Motor Test
stalls and failure to load section and Inspecting the Vertical Lift and Lift Block
Basket jams
baskets. section).
Paint on long gripper Replace long gripper jaw (refer to the Gripper Jaws
damaged section).
Basket jams on slide guide Inspect slide guide (refer to the Inspecting the Slide
due to seized slide guide. Guide Assembly section).
Basket slider jams on slides Inspect basket eject assembly and upper slide retention
leading to lift stall on move to (refer to the Inspecting the Output Pusher and Upper
fully closed. Slide Retention section).
Staining protocol is leaving a Reduce the camera slide threshold (parameter 72) by
residue on the slide, making it 10. Repeat as necessary.
harder for the camera to see
Note
the slide. Slides in positions
1, 2, 3 and 20 always Lowering will increase the likelihood that ClearVue will
coverslipped, whilst other attempt to remove slides that don't exist. This will slow
positions are always or down the instrument and will also lead to increased
randomly missed. wear.
Slides not Gripper linkage or cam worn Replace Gripper linkage and cam (refer to the Gripper
coverslipped excessively. Actuator section).
Chipped or broken slide(s) Ensure only undamaged slides are loaded onto the
loaded into basket. instrument.
Paint on long gripper Replace long gripper jaw (refer to the Gripper Jaws
damaged. section).
Dispense head needle height Set dispense head needle height correctly (refer to the
set incorrectly. Checking and Adjusting the Needle Height section).
Basket open assembly not Inspect basket open assembly (refer to the Basket
pulling slider fully clear of Open Motor Test section and Inspecting the Basket
slides. Open and Lower Slide Retention section.
Short gripper jaw breaks slide Check short gripper jaw stop cam setting (refer to the
during vertical index. Inspecting the Cleaning Station Assembly section).
Camera fault leading to erratic Confirm using Log file data and replace if necessary
sensing of basket top and jaw (refer to the Engineer’s Log Extraction section and
'y' positions. Camera Board Replacement section).
Skewed coverslips Suction Cup dirty or worn Clean or replace Suction Cup
Too much xylene carryover Shake Basket to remove excess xylene before
Slides are too wet
from staining loading
when removed
Fan continues to run when filter Check filter switch is working (refer to the I/O Tabs
is removed. – Inputs section).
Fan speed does not vary when • Check unload door switch operation (refer to the
unload door is opened. I/O Tabs – Inputs section).
Note
Fan will run at high speed with unload door closed,
for approximately 25 mins after a basket has been
processed.
Note
Solenoid valves not sealed
correctly. Do not modify or disassemble the solenoid valve. If
the valve has been tampered with, replace the
whole assembly.
Pipe not sealed onto sensor. Replace the pipe between the sensor and the filter.
Filter leaking. Replace the filter between the sensor and the valve.
Note
Mountant bottle not
holding pressure. Over-tightening of fittings may cause thread to strip.
Fittings leaking.
• If fittings are in correctly but are still leaking, use
PTFE tape on the thread as a temporary fix.
Note
Solenoid valves not sealed
correctly. Do not modify or disassemble the solenoid valve. If
the valve has been tampered with, replace the whole
assembly.
Pipe not sealed onto sensor. Replace the pipe between the sensor and the filter.
Filter leaking. Replace the filter between the sensor and the valve.
Fittings into mountant pump • Ensure line is fully pushed home in fitting.
solenoid block leaking.
• Tighten fittings to 3Nm or replace.
Coverslip lower solenoid 1 Check solenoid is switching and sealing (refer to the
fault. Vacuum System Test section).
Debris on suction cup. Clean suction cup with a cloth or paper towel.
Coverslip lower solenoid 2 Check solenoid is switching and sealing (refer to the
fault. Vacuum System Test section).
Note
Do not tamper with the valve settings.
Leak on mountant pump valve.
• Flush system twice.
• De-gas.
Note
Do not tamper with the valve settings.
Leak on mountant pump valve.
• Flush system twice.
• Replace as required.
Note
Do not tamper with the valve settings.
Leak on mountant pump valve.
• Flush system twice.
• Replace as required.
• No action required
Tools Required
The following tools are required to service the
Epredia ClearVue:
• Set of metric allen keys (must include 2.5mm)
• #1 Posidrive screwdriver
• #2 Posidrive screwdriver
• Set of feeler gauges
• Small flat-blade screwdriver
• Medium flat-blade screwdriver
• Set of metric spanners (wrenches)
• Small external circlip pliers
• Tube cutter
• Side cutter
• 4mm pneumatic 'T' coupling and pipe.
(AP14467 & 100mm of M03681)
• Adjustable torque driver (0.5-5.5Nm. with a
resolution of 0.1Nm or better)
• Spring balance (0-3kg with a resolution of 0.1kg
or better)
• Dial Test Indicator (DTI) Gauge (with a resolution
of 0.02mm or better)
• T61627 Cleaning station setting tool.
• T61645 Gripper setting DTI bracket & gauge
plate.
Step 3
• Unscrew the mountant bottle cap.
• Remove the collar by lifting it over the mountant
bottle spout.
• Replace bottle cap after collar is removed.
Step2
• Remove the 2 fixing screws as shown.
• Remove the back panel - the Earth connection
lead can be left attached.
• Disconnect the filter fan connector from the main
PCB.
Step 6
• Remove the 2 fixing screws shown.
• Remove the right hand cover.
Note
Step 5 When refitting the right-hand cover, take care to
• Open the access door and the unload door. ensure that the pipe to the slip carriage is retained
within the slot in the cover.
• Loosen the 2 fixing screws, labelled 'A', to
release the main cover from the bracket on the
vertical plate.
• Remove the 2 fixing screws, labelled 'B', which
secure the bracket to the vertical plate.
• Making sure the filter / fan connector has been
disconnected (Step 2.3), carefully lift the main
cover off the instrument.
Note
Take care not to trap fingers or bang head on doors
when lifting the cover off.
Note
When replacing the LHS assembly, ensure the wires
indicated are not trapped between the front.
inner liner and the LHS assembly, and ensure the
rear cover earth strap is routed correctly.
Step 8
• Remove the dispense head cleaning station from
its mount.
• Unscrew the stub shaft.
• Carefully disconnect the pipes running to the
pump assembly (located underneath the debris
liner) and the silencer.
Note
Take note of the pipe routing to facilitate re-
assembly
• Remove the 6 screws which secure the debris
liner.
• Manoeuvre the debris liner out in the direction
shown.
Main Cover
2 A79210038
Assembly
Mountant Bottle
6 A79230151
Cover
To remove the lift block assembly: • The vertical lift plunger can now be removed.
Note
The plunger can be replaced with the lift block in-
situ.
To remove the lift block plunger:
And then.
• Carry out the Mountant Bottle Pneumatic Test. Item Part Number Qty. Description
• Carry out the Vacuum System Test.
1 A79230016 1 Slide Pusher
2 AP15176 2 Spring
Actuator Assembly
To remove the actuator assembly:
To set the bracket position: To refit the actuator assembly follow steps 1 to 7 in
reverse order.
• Screw tool T61627 to the top of the dispense
head cleaning station actuator. Note
• Move the actuator up until the tool touches the It is advisable to wind the linear actuator nut off the
underside of the dispense arm. end of the shaft to gain access and tighten the 3
• Take control of the 'N_Pot' motor from flange fixing screws.
Production Services (refer to the Motor Tab Replace the nut and push it into contact with the
section). motor before tightening the bracket fixing screws.
• Move the opto assembly upwards until the 'UP'
opto is just activated, and then lock the opto
assembly in place.
• Check the setting by using the minor increment
arrows to move upwards – the opto should not
be seen - and downwards - the opto should be
seen.
• Replace the adaptor shaft and the dispense
head cleaning station.
1 A79220051 1 Actuator
Assembly
Item Part Number Qty. Description
Dispense Head Cleaning Station Actuator
1 A79220070 1 Cleaning
Assembly
Station
To remove the dispense head cleaning station Actuator
actuator assembly:
And then.
• Remove the dispense head cleaning station and
the adaptor shaft from the top of the actuator • Carry out Performance Test 2.
rod. • Carry out Performance Test 1.
• Remove the 2 mounting plate fixing screws
located around the back of the vertical plate.
• Disconnect the electrical connector from the rear
I/F PCB.
• Remove the actuator assembly and mounting
plate as a single unit.
• Remove the 4 actuator fixing screws to release
the actuator from the mounting plate.
To refit the actuator assembly:
• Disconnect the actuator electrical connectors • Perform a bead test (refer to the Perform a Bead
from the front I/F PCB. Test section).
Note
Ensure all wires are secured away from the moving
parts and the syringe is fully screwed in to a firm
finger-tightness.
And then.
Gas Complete
If the circlip is removed for any reason it must be • If refitting the bottom pulley, ensure the flag is
replaced with a new one - do not reuse the original! oriented as shown.
Tip
If the drive arms are held tightly to their shafts, insert
the screw in the opposite side of the arm and a thin
piece of metal between the jaws to create a jacking
surface. Tighten the screw to produce some
clearance.
• Remove the pin to allow the pulley shaft to pass
through the vertical plate.
3 A79220047 1 Motor
Assembly
Note
Do not tighten the pillar screws yet.
• Orient the bottom pulley as described in the
previous step to ensure the flag is correctly
positioned in relation to the opto switch.
• From the front, fit the upper drive arm - do not
tighten yet!
• Re-insert the pin in the lower pulley shaft, then fit
and secure the lower drive arm (inc. main
mounting block).
• Move the lower drive arm to its TDC position and
place a straightedge along the vertical side face.
• Align the upper and lower drive arms so that they
are parallel, using the straightedge as a guide.
• Tighten the upper drive arm.
• Using a square, as shown, ensure the main
mounting block is perpendicular to the vertical
plate, then tighten the pillar screws.
• Loosen the spring fixing nut to allow the
Step 4
tensioning spring to rotate.
• Carefully stretch the tensioning spring so that the
Note
loop on the free end can be hooked over the
If necessary, remove tension from the belt by loosened upper fixing screw.
loosening the 2 tensioning system fixing screws. • Rotate the dispense head mechanism to ensure
• Remove the lower fixing screw and take off the that any belt slack is evenly distributed.
spring washer - then replace the fixing screw and • With the tensioning spring in position, tighten the
tighten it. lower fixing screw.
• Remove the home opto to prevent damaging it. • Un-hook the tensioning spring from the upper
• Back of the lower fixing screw by ¼ of a turn to fixing screw and return it to its 'parked' position
allow the tensioning system to slide but still - tighten the Nyloc to fix it in place.
remain well located. • Tighten the upper fixing screw.
• Remove the lower fixing screw, replace the
spring washer and then replace and tighten the
screw.
• Re-check the drive arm alignment using a
straightedge.
1 A79220051 1 Actuator
Assembly
And then.
• Initialise the instrument. • Turn 'Prep' to '0' (refer to the Eng Tab – Page
2/7 section).
• Carry out Performance Test 2.
• Load and process 5 empty baskets.
Basket Push Motor Assembly Parts • Remove the empty baskets from the unload rail.
Replacement • Turn 'Prep' to '1' (refer to the Eng Tab – Page
To remove the basket push actuator assembly: 2/7 section).
• Load and process a full basket.
• Disconnect the electrical connectors from the
main PCB. • Ensure all slides are coverslipped without any
problems.
• Remove the 2 bracket fixing screws from the
front of the vertical plate.
• Withdraw the actuator assembly from the lead-
nut by pulling in the direction shown.
• Remove the 3 flange fixing screws to release the
flanged lead nut.
• Remove the 4 actuator fixing screws.
To refit the basket push actuator assembly follow
steps 1 to 5 in reverse.
Identification of Parts
7 A79210124 1 Interconnect
Item Part Number Qty. Description
PCB Kit
Solenoid Assy
8 A79210121 1 Processor
(Upper) –
PCB Kit 1a A79510015 1
Pressure De-
Gas Complete
Power Supply
To remove the PSU:
• Ensure the mains power and battery isolation
switches are in their 'Off' positions. Item Part Number Qty. Description
1 AP14192 2 Battery
And then.
Fan Assembly
To remove the fan assembly:
Speaker
To remove the speaker assembly:
• Remove the electronics box cover and PSU
bracket (refer to the Electronics Box section).
• Remove the 4 push-fit rivets to release the
speaker assembly.
To replace the speaker assembly follow steps 1 and
2 in reverse.
2 A79220022 1 Interconnect
PCB
3 AP14741 1 Processor
PCB
Battery Board
F2 Battery
5 A79210152 1
Fuse 2 - F12A,
250V
And Then.
• Initialise the instrument.
• Carry out Performance Test 3.
• Carry out Performance Test 1.
• Set the top face of the motor pulley to a height • Release the push-fit rivets from above the
of 17mm from the mounting plate as shown. horizontal plate to allow the opto switch to be
removed.
• Tension the belt using a spring balance to apply
1.7-1.8kg of force to the belt tensioning bracket To refit the slip dispense opto switch follow steps 1
whilst tightening the locking screw. to 3 in reverse.
1 A79220051 1 Actuator
Assembly
And Then.
And then.
Note
Ensure all wires are neatly cable-tied in their original
bundles.
Note
When refitting the timing belt, tension it to 2kg using
a spring balance.
And then.
And then.
• Initialise the instrument.
• Carry out Performance Test 2.
Note
When refitting the opto switch ensure the wires are
routed as shown to leave clear access to the
leadscrew end slot.
Note
When screwing the 2 halves of the rail back
together, ensure the faces are properly aligned.
Item Part Number Qty. Description
3 59920128 1 Proximity
Switch
Item Part Number Qty. Description Item Part Number Qty. Description
• Remove the outer instrument covers (refer to the • Use the 'X-Spot' function to check touch screen
Outer Case Removal section). operation (refer to the Eng tab – Page 7/7
section).
• Remove the Opto cover and the Display Cable
cover. • Adjust the viewing angle and brightness of the
screen as required (refer to the Adjusting the
• Remove the 2 fixing screws which hold the
Screen Settings section).
display screen assembly to the horizontal plate.
• Use the INPUTS screen to check the operation
• Turn the display screen over and remove the
of the debris door (refer to the I/O Tab – Inputs
invertor PCB cover as shown.
section).
• Disconnect all the connectors to the display
• Use 'Testslip' (refer to the Eng tab – Page 2/7
PCB.
section) and 'Slip QC' (refer to the Eng tab –
• Remove the 4 SEMs to allow the display PCB to Page 6/7 section) to check the operation of the
be removed. coverslip dispense sensors.
To refit the display PCB follow steps 1 to 6 in
reverse.
Invertor PCB
1 A79230139 1
Cover
Slide Guide
Slide Guide Parts Replacement
5 A79230079 1 Mounting
Note Block
The leaf spring can be replaced with the slide guide And then.
in-situ; remove the lower main guide fixing screw
and pull the leaf spring out. • Initialise the instrument.
• Carry out Performance Test 2.
To remove the slide guide assembly:
• Carry out Performance Test 1.
• Remove the 4 assembly fixing screws.
To disassemble the slide guide assembly:
Note
Ensure that end stop sits flush against the alignment
face when fitted and tightened. And then.
Note • Initialise the instrument.
Apply blue Loctite 242 to the threads of the fixing • Use the 'Snapshot' function to check that the
screw. image shows the grippers (refer to the ENg Tab
– Page 5/7 section).
And then.
• Check jaw / slide alignment using Production
• Check the coverslip dispense end stop height test 5 (refer to the Eng Tab – Page 1/7 section).
(refer to the Coverslip Dispense End Stop Height
• Carry out Performance Test 1.
section).
• Carry out Performance Test 2.
• Carry out the 'Auto slip' function (refer to the Eng
tab – Page 6/7 section).
• Carry out the 'test slip' function (refer to the Eng
Tab – Page 2/7 section).
Note
Ensure the tensioning force is applied as close to
the centreline of the fixing screws as possible.
And Then.
Ensure the thrust washer is in place as shown. • Carry out Performance Test 1.
• Use the INPUTS screen to check the operation of the filter switch and
extraction fan (refer to the I/O Tab – Inputs section).
Fan Microswitch
• The feedback frequency should be > 80Hz with the unload door open.
• The feedback frequency should be > 50Hz with the unload door closed.
• Check, and adjust if necessary, needle height (refer to the Checking and
Adjusting the Needle Height Section).
• Check, and adjust if necessary, the coverslip transfer head hard stop
position (refer to the Checking and Adjusting the Coverslip Transfer Head
Short and Long Gripper Jaws Hard Stop Section).
• Carry out ProdTst6 (refer to the Eng Tab – Page 1/7 section).
• Carry out a Bead Test (refer to Carry out a Bead Test section).
Note
Handle the new decay reservoir with care. Handle at
the ends only to avoid contamination of the
ventilation hole.
• Connect a length of pipe between the elbow
coupling in the lower solenoid assembly and the
decay reservoir. Use the pipe provided in the kit
due to the potential change in length.
Note
The vacuum must be within the limits -4.5psi + or –
0.5. If it is necessary to adjust the vacuum outside
its limits of -4.5 + or – 0.5 for the decay time to be
within the within the limits 2.8 to 3.2 seconds, this is
unacceptable, and would usually indicate that the
decay reservoir is faulty, and needs to be replaced.
9990610 Filter
AP14371 Microswitch
AP15217 Syringe
AP15186 PSU
Couplings
Part No Description
Belts
Part No Description
Linear Rails
Part No Description
Electrical Drawings
Please refer to the electronic version of
the Electrical Drawings provided.
MECH This code is a general description that could be used for multiple reasons
3 Cam. Line width 580 Width of image (divide by 2 for actual pixels)
57 Nozzle Pot Purge Amount 95 Purge amount before entering cleaning station
67 Prep Final Pause 150 Pause (10 x 10ms) before removing suction cup
68 Cam Lines Down 150 Where to start pulling camera data from FPGA
80 Final Slow Position 10 Position of final slow speed in quads above hard stop
82 Hi Speed Stop 2 80 High speed stop (auto stop) in quads above hard stop
No. of pixels between top of slide and jaw target value. Can
92 Slide Adjust Target 4
be set using ProdTst5.
97 Slip Put Down Adjust 5 Target of X quads above hard stop during coverslipping
This is a quick reference sheet to highlight areas in The voltages readings are in units of approximately
the log file that need to be scrutinised, this could be 10mV. 2400 ≈ 24V.
a sheets that a service engineer could print and file V PSU is the voltage detected from the PSU. This
for reference. will typically be around 24V. Values of 18-20V are
typical at power fail (when the unit is switched off).
Errors
V BATT1 is one of the backup batteries. This will
List of every error in the log file (shows all slips errors
typically be in the range 12-15V depending on state
& not just the ones the user see’s)
of charge. Lower values can be expected during
periods when the unit is running on batteries.
Prep decay chart
V BATT2 is the second of the backup batteries.
Prep decay data in easy to read chart format - see
When the unit is running on batteries, this will show
below for further explanation on prep decay charts.
the total voltage of the two batteries, typically 26-
Warnings 28V immediately after a mains power fail.
List of all the warnings in the log file. The OC and STL signals indicate the charger status.
This will slow the machine down, but will not affect
the quality of the prep. The priority of the customer
should be considered: Prep quality V’s speed of the
machine. Errors are reported if the slip has not been
released after 13 seconds.
Use [ ctrl ] + [ f ] to find the date or time required for the actual decay time value.
mp_load
This has been used as a development tool along with 'dispense end' values to determine how much mountant
has been dispensed.
The Quad value is from the encoder and is the position actually reached. The position value is the position
demanded of the motor and where it is aiming for.
A difference of more than 100 between quad and position shows there has been some stall on the motor.
The syringe should refill to±0.5mm each time (approx. 165 quads).
Basket_times
Time is dependent on the number of slides in the basket, the decay time and how long the customer takes to
clear any errors.
Profile W
Date Time Used B Set
Version Set
The profile version controls the shape of the bead and affects the prep quality.
Slip_dispense
This page shows you how many slips have been dispensed, the engineering error code with how many errors,
plus the % of errors in that category.
If double slips are reported find out if there are actually 2 slips dispensed on the carriage together. If so check
the end stop height, if not, use the Autoslip to reset the thresholds for no slip and double slips. If length errors
are reported check there is sufficient vacuum on the carriage.
09/11/2008 11:27:40 GOOD INPUT STALL DETECTED: quad: 13554 Min Quad seen:13554 Pos:13623
09/11/2008 11:27:42 Basket loaded to lift success @ quad = 14169 and position = 14213
Camera jaw_x and jaw_y are re-tested to ensure no change in image has been seen. Ignore NEW POS 500
value.
09/11/2008 11:27:43 camera JAWY_Y re-tested from below, old pos=065 new pos=500
This line shows the prep head has checked the pin width on the prep transfer head and has detected a normal
(around 40 ) prep head in the END position.
09/11/2008 11:27:43 AUX CAM INIT NEW: jaw_x, 226, jaw_y, 064 OLD: jaw_x, 225, jaw_y, 065 USED:0
09/11/2008 11:27:43 Camera Lens QC Check: High thresh: 037, Low Thresh :039, CLEAN VALUE :002
This shows the quad of the basket open slider when fully opened.
Basket processing is about to begin. OFFSET target is parameter 92 value. Jaw at is current jaw_y value.
09/11/2008 11:27:47 (BIG BASKET CODE) Basket top 1,00085, Basket top 2,00085, White Strip bot,00085,
BIG(1)SMALL(0),1 At lift quad, 09610
Second basket top position, now at SMALL basket position. You can see the basket top values are 71 and 69.
two pictures are taken for basket top, one is 11 quads higher than the other. This gives the values of 71 and 69
and are different to white strip bottom - this means a valid basket top has been found. Notice BIG,SMALL VALUE
is 0 indicating lift at SMALL position.
09/11/2008 11:27:49 (BIG BASKET CODE) Basket top 1,00071, Basket top 2,00069, White Strip bot,00085,
BIG(1)SMALL(0),0 At lift quad, 09059
The lift and camera have worked out from all the info above, the correct position to move to for processing the
basket. This is known as the final 1st slide position.
09/11/2008 11:27:49 (BIG BASKET CODE) Final 1st Slide Position,08723, Total Slides to Process,00020,
Basket top1,071, top2,069
This values shows the colour of the basket slider, low values indicate BLACK sliders, high values for white.
A quick reminder of the profile version and mountant settings used on this basket.
09/11/2008 11:27:49 start of basket processing - Profile V:87 @ setting :05 Black:05 White:12 Slide Thresh:095
This chunk of events shows a complete cycle of removing the slide and performing the prep, these events should
be repeated 20 times for small baskets. Pos values indicate what is visible to the camera, pos0 is current slide
slot, 1 is next and 2 is after next slot. Values of 15 will detect a slide as present. Decreasing the camera slide
threshold parameter will increase these numbers but will more likely cause ClearVue to grab slides not present.
Decay time is another important number here, which gives indication to machine performance within the
pnumatic system.
This quad value is that of the lift when the flag passed the upper lift opto. Variation in this value should be minimal.
Appendix D2 – Mountant System Screens .......... 252 Inspecting the Mountant Pump Actuator and Syringe
............................................................................. 72
Appendix D3 – Options Screens ......................... 253
Inspecting the Output Pusher and Upper Slide
Appendix E – Understanding Log Files................ 254
Retention .............................................................. 71
Further Information........................................ 256
Inspecting the Output Rail ..................................... 71
Inspecting the Pneumatic Circuit ........................... 73
B Inspecting the Slide Grippers ................................ 69
Basic Operation ......................................................... 23 Inspecting the Slide Guide Assembly..................... 69
Daily Tasks ........................................................... 24 Inspecting the Vertical Lift and Lift Block ............... 68
Weekly Tasks ....................................................... 24 Performance Test ................................................. 68
Basic Structure .......................................................... 12
Basket Eject and Upper Slide Retention................ 13 C
Basket Open and Lower Slide Retention ............... 12
Change the Carbon Filter ............................................ 25
Camera ................................................................ 14
Change the Coverslip Transfer Head Position ............. 92
Cleaning Station Assembly ................................... 14
Change the Purge Tray and Debris Tray ..................... 29
Covers and Filter .................................................. 14
Change the System Language .................................... 95
Coverslip Dispense ............................................... 13
Cleaning ................................................................... 105
Coverslip Transfer Head ....................................... 13
Cleaning the Camera .......................................... 119
Input Rail .............................................................. 12
Cleaning the Coverslip Transfer Head ................. 118
Mountant Bottle .................................................... 14
Cleaning the Dispense Head Cleaning Station ..... 109
Mountant Dispense Head ..................................... 13
Cleaning the Gripper Return Plate ....................... 116
Mountant Pump Actuator and Syringe .................. 14
Cleaning the Mountant Bottle Cap ...................... 106
Output Rail ........................................................... 13
Cleaning the Mountant Bottle Seal ...................... 107
Pneumatic Circuit ................................................. 14
Cleaning the Mountant Dispense Needle ............ 114 ENG Tab - Page 4/7 ............................................. 56
Cleaning the Slide Grippers ................................ 117 ENG Tab - Page 5/7 ............................................. 57
Cleaning the Slip Dispense Carriage ................... 112 ENG Tab - Page 6/7 ............................................. 58
Cleaning the Slip Dispense Skirt ......................... 115 ENG Tab - Page 7/7 ............................................. 60
Cleaning the Suction Cup ................................... 110 Engineers' Log Extraction ......................................... 176
Cleaning the Touch Screen................................. 115 Example of Varistain Gemini Basket ............................ 21
Cleaning the Xylene Tray Seal ............................. 108
Cleaning and Maintenance Precautions .................... 101
F
Company Information ................................................... 3
Fill the Dispense Head Cleaning Station ...................... 30
Compatibility .............................................................. 19
Fill the Mountant Bottle ............................................... 28
Contact address .......................................................... 3
Fit the Extraction Kit ................................................... 26
contents....................................................................... 4
Flush the System ........................................................ 32
Coverslipping Method ................................................ 22
Front view of ClearVue ................................................ 20
Create the Engineers Log ........................................... 95
Functional Tests ......................................................... 61
D
G
Degas the Mountant Bottle......................................... 32
General Description .................................................... 12
Design Purpose ......................................................... 19
Special design features of the ClearVue ................ 12
Disposal of Sealed Lead Acid Batteries ........................ 8
E I
I/O Tab ....................................................................... 43
Earth Continuity and Insulation Resistance Tests ........ 62
I/O Tab – I2C ........................................................ 45
Electronics Assembly ................................................. 15
I/O Tab – INPUTS ................................................. 43
Back Interface Board ............................................ 18
I/O Tab – LINKS.................................................... 46
Battery Board and Batteries.................................. 17
I/O Tab – OUTPUTS ............................................. 44
Camera Board ...................................................... 18
I/O Tab – VOLTAGES ........................................... 46
Electronics Box - Miscellaneous Items .................. 17
Identification of Parts (front) ........................................ 20
Front Interface Board............................................ 18
Identification of Parts (rear) ......................................... 20
Interconnect Board ............................................... 17
Identifying Problems with Slides
Main Board .......................................................... 15
Diagnosis Flowchart ............................................ 142
Mains inlet and power supply................................ 15
Excessive Bubbles .............................................. 130
Miscellaneous Items ............................................. 18
Prepared Slides – Troubleshooting ...................... 131
Motors ................................................................. 18
Individual Motor Tests................................................. 62
Overview .............................................................. 15
Basket Eject Motor Test ........................................ 63
Processor Board .................................................. 15
Basket Open Motor Test ....................................... 63
Pumps (Air) ........................................................... 18
Coverslip Dispense Motor Test.............................. 63
Sensors ................................................................ 18
Coverslip Transfer Head Motor Test ...................... 62
Solenoid valves..................................................... 18
Dispense Head Cleaning Station Motor Test ......... 64
ENG Tab .................................................................... 50
Gripper Motor Test ............................................... 63
ENG Tab - Page 1/7 ............................................. 51
Input Rail Motor Test............................................. 62
ENG Tab - Page 2/7 ............................................. 53
Lift Block Motor Test ............................................. 62
ENG Tab - Page 3/7 ............................................. 55
Mountant Pump Motor Test .................................. 64
Inside ClearVue .......................................................... 20 P
Install the Offset Coverslip Transfer Head ................... 98 PARAM Tab ............................................................... 43
Instrument Verification Tests....................................... 74 Parts Replacement ................................................... 177
Carrying Out a Bead Test ..................................... 88 Outer Case Removal ........................................... 178
Checking and Adjusting Gripper-to-Gripper Alignment Parts Replacement by Sub-Assembly ................. 182
............................................................................ 81 Safety ................................................................. 177
Checking and Adjusting Short Gripper Stop Cam . 86 Tools Required ................................................... 177
Checking and Adjusting the Coverslip Transfer Head Parts Replacement by Sub-Assembly
Hard Stop Checking the Position .......................... 84 Basket Open & Dispense Head Cleaning Station
Checking and Adjusting the Coverslip Transfer Head Assembly Parts Replacement ............................. 184
Sprung Pads ........................................................ 80 Basket Push Motor Assembly Parts Replacement192
Checking and Adjusting the Needle Height ........... 83 Camera Board Replacement ............................... 212
Checking and Setting Coverslip Dispense Optical Coverslip Dispense Motor Assembly Parts
Sensors ................................................................ 87 Replacement ...................................................... 200
Checking Door Sensors and Filter Switch ............. 86 Coverslip Transfer Head Motor Assembly Parts
Checking Software, FPGA and Pump Profile Version Replacement ...................................................... 190
............................................................................ 85 Display PCB Parts Replacement ......................... 208
Checking the Coverslip Transfer Head Position ..... 87 Electronics Box Individual Component Replacement
Coverslip Dispense End Stop Height .................... 84 ........................................................................... 195
Coverslip Dispense System Test ........................... 80 Electronics Box Parts Replacement .................... 193
Mountant Bottle Pneumatic Test ........................... 78 Front I/F PCB Parts Replacement ....................... 204
Performance Test 1 .............................................. 75 Gripper Actuator Parts Replacement ................... 203
Performance Test 2 .............................................. 77 Gripper Jaws ...................................................... 216
Performance Test 3 .............................................. 78 Input Motor Assembly Parts Replacement ........... 205
Resetting Parameters ........................................... 86 Input Rail Assembly Parts Replacement .............. 206
Vacuum System Test............................................ 79 Inverter PCB Parts Replacement ......................... 209
Introduction to ClearVue............................................. 10 Lift Block Leadscrew Parts Replacement ............ 214
Introduction and Safety......................................... 11 Lift Block Parts Replacement Procedure ............. 183
Safety ............................................................. 11 Lift Motor Parts Replacement .............................. 213
Miscellaneous Tests for Other Replacements ...... 215
Maintaining the Xylene Tray Level ............................... 27 Slide Guide Parts Replacement ........................... 210
Maintenance ............................................................ 101 Slip Dispense Carriage, End Stop and Support Arm
Parts Replacement ............................................. 211
Manually Abort a Basket ............................................ 38
Solenoid Assembly Parts Replacement ............... 189
MOTOR Tab .............................................................. 48
Touch Screen or Proximity Switch Parts Replacement
........................................................................... 209
Vacuum Regulator Parts Replacement ................ 189
Prepare the ClearVue for Storage ............................. 104 System Interfacing ...................................................... 21
Production Services ................................................... 41 System Specifications ................................................ 21
Introduction .......................................................... 42 Electrical Specifications ......................................... 21
Purge the System ...................................................... 33 Environmental Specifications ................................. 21
Physical Specifications .......................................... 21
R
Rear of the ClearVue .................................................. 20 T
Remove and Replace the Coverslip Hopper ............... 34 Technical Drawings .................................................. 231
Remove Baskets from the Load & Unload Rail............ 39 Electrical Drawings.............................................. 231
Remove Baskets from Vertical Lift .............................. 40 Pneumatics Drawings ......................................... 232
Remove Slides during Coverslipping........................... 39 Troubleshooting ....................................................... 120
Remove the Mountant Bottle .................................... 103 Error Code Cross-Reference Table ..................... 126
Replacing Seals ....................................................... 102 Error Screens...................................................... 121
Identifying Problems with Slides .......................... 129
Perform a Bead Test ........................................... 128
S
Quick Reference to Errors ................................... 125
Safety Information ........................................................ 7
Telephone Support ............................................. 121
Chemical Safety ..................................................... 8
Troubleshooting Tables ............................................ 143
Environment ........................................................... 9
Basket Jams ....................................................... 154
General Safety ........................................................ 7
Breaking Coverslips ............................................ 152
Introduction ............................................................ 7
Breaking Slides ................................................... 157
Warranty Statement................................................ 9
Coverslip Mis-Dispense....................................... 150
Select the Coverslip Position ...................................... 91
Coverslip Position Wrong on Slide....................... 146
Service Schedule ..................................................... 219
Coverslip Vacuum Faults ..................................... 167
Routine Maintenance Schedule .......................... 221
Dispense Head Dirty ........................................... 146
Settings ..................................................................... 89
Dispense Needle Dirty/Blocked ........................... 148
Shutting Down the ClearVue ...................................... 35
Excessive Drying of Slides................................... 160
Slide Retainer Types .................................................. 97
Extraction System Faults ..................................... 162
Software Update ...................................................... 218
Loss of Parameters and Settings ........................ 161
Spares List ............................................................... 226
Machine Dead – No Power ................................. 144
Belts................................................................... 230
Mountant Dryback .............................................. 148
Couplings ........................................................... 229
Mountant Overspill .............................................. 147
Covers ............................................................... 230
Mountant Pump and Syringe Faults .................... 169
Electronics Box Assembly................................... 228
Part Broken Coverslips ....................................... 159
General .............................................................. 226
Pneumatics for Mountant Bottle .......................... 163
Leadscrews and Nuts ......................................... 229
Skewed Coverslips ............................................. 159
Linear Rails ......................................................... 230
Slide Jams .......................................................... 149
Link Arm Assy .................................................... 230
Slides not Coverslipped ...................................... 155
Mountant Bottle Assembly .................................. 229
Slides too wet ..................................................... 159
Slide Guide Assembly ......................................... 228
Touch Screen Assembly ..................................... 229
Start up the ClearVue ................................................. 30 U
Symbols....................................................................... 3 Unload a Basket ......................................................... 37
Update the System Software...................................... 96
USA Distributor ............................................................ 3 V
View through the Access Door.................................... 20