Anand Pharmacy College has outlined the syllabus for the B.Pharm program for the academic year 2024-25, focusing on Physical Pharmaceutics - 1. Key topics include surface and interfacial phenomena, states of matter, solubility, and buffer solutions, with references to notable textbooks in the field. The first sessional examination is scheduled for March 29, 2025.
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B010201TP_1st Sessional_Syllabus
Anand Pharmacy College has outlined the syllabus for the B.Pharm program for the academic year 2024-25, focusing on Physical Pharmaceutics - 1. Key topics include surface and interfacial phenomena, states of matter, solubility, and buffer solutions, with references to notable textbooks in the field. The first sessional examination is scheduled for March 29, 2025.
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ANAND PHARMACY COLLEGE, ANAND
(An Autonomous College under UGC Regulations 2023)
‘Managed by Shri Ramkrishna Seva Mandal
(Approved by PCI, NAC Aceredited ~ A+ Grade, 3.38 C!
rding University: Gujarat Technological University, Ahmeda
‘Academic Year: 2024 -25
SYLLABUS
PA)
First Sessional Examinations Date: 29/03/25
Name of Program B.Pharm Semester? Year ae
Subject code
‘BO10201TP
Subject Name
Physical Pharmaceutics - 1
Name of Subject in-charge Ms, Diruvixa Patel
No. |_ Faculty
Sr. | Nameof | Topics Covered Subtopics Covered
Ref.
Books*
1. [DP
Surface and Interfacial | Liquid interface, surface & interfacial
phenomenon tensions (Introduetion, _ Difference,
Equation), surface free energy,
Measurement of surface & interfacial
tensions- capillary rise, drop weight and
drop count, Wilhelmy plate, Du Nouy ring
method, spreading coefficient, adsorption at
liquid interfaces, surface active agents,
HLB Scale - methods to determine HLB
value, applications, _solubilisation,
detergency, Adsorption at solid interface
(Langmuir and Freundlich isotherm),
electrical properties of interphase — double
layer theory and zeta potential.
13
DP
KSP
States of Matter and Introduction, properties, changes in the
properties of matter state of matter, types — solid crystalline,
solid amorphous, glassy states,
polymorphism, pseudo- polymorphism,
liquid crystals & liquid complexes. Liquid
state - latent heats, vapour pressure,
sublimation critical point, eutectic
mixtures, gases, aerosols — inhalers, gas
laws, relative humidity. phase equilibria &
Phase rule: one, two & three component
systems. Physicochemical properties of
drug molecule: tive index, optical
rotation, dicleetric constant, dipole
moment, dissoc ‘constant,
determinations and applications.
ey weSolubility expressions, mee!
| solute-solvent interactions,
parameters, b
|
| solv &
| approach tothe
ly of drugs, diffusion principles in
ns. Solubility of gas
iquids, solubility of liqui i
(binary solutions, ideal solutions) Raoult’s
law, teal solutions. Partially miscible
| liquids (phenol-water System,
triethylamine-water system, nicotine-water
system). Ternary phase diagram (benzene,
alcohol, water). Critical_ solution
temperature and applications. Distribution
| law, its limitations and applications.
DP PH, buffers and Isotonic | Sorensen’s pH scale, pH determination 34
| KSP solutions (clectrometric and calorimetric),
Applications of buffers.
List of References:
1. Physical Pharmacy by Alfred Martin
2. Physical Pharmaceutics by Ramasamy C and ManavalanR.
3. Physical Pharmaceutics by C.V.S. Subramanyam
4. Test book of Physical Phramacy, by Gaurav Jain & Roop K. Khar
Sign of Faculty: wpe Sign of Subject I/C: & Sign of HO!
3
x
a\s\er Date: 229 [3\26 Date:
Date:
Seal of Institute