Cardiovascular System › Hyperlipidemia Hyperlipidemia: Treatments
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HYPERLIPIDEMIA TREATMENTS
The goal of hyperlipidemia treatment is to prevent
atherosclerosis and other cardiovascular diseases,
and, in the case of hypertriglyceridemia, to prevent
pancreatitis.
Prevention and treatment of hyperlipidemia comprises
lifestyle modifications that promote cardiovascular
health, including a low-fat diet, increased physical activity,
weight loss, and avoidance of cigarette smoking.
When those measures are not enough, medications can be
prescribed.
HYPERLIPIDEMIA MEDICATIONS
Statins
HMG-CoA reductase inhibitors: upregulate hepatic LDL
receptors, which lowers serum levels of LDL.
Statins can reduce LDL levels by 20-60% , and reduce
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triglyceride levels as well.
Adverse effects include myalgia and myositis; some
statins are associated with increased risk of diabetes.
Statins are contraindicated in liver disease, and can interact
with several drugs, including warfarin.
Statins are a mainstay treatment of hyperlipidemia and
have been shown to reduce the risk of cardiovascular
disease and reduce the progression and mortality from
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