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Clinical biochemistry

The document outlines the course structure for a Bachelor of Science in Clinical Biochemistry under a Choice Based Credit Scheme, detailing the courses and credits for each semester. It includes specific courses such as Biomolecules, Clinical Immunology, and Clinical Pathology, along with their respective practical components. Additionally, it provides an overview of the first semester's core course, including objectives, learning outcomes, and practical laboratory exercises.

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Atif Rafiq
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23 views2 pages

Clinical biochemistry

The document outlines the course structure for a Bachelor of Science in Clinical Biochemistry under a Choice Based Credit Scheme, detailing the courses and credits for each semester. It includes specific courses such as Biomolecules, Clinical Immunology, and Clinical Pathology, along with their respective practical components. Additionally, it provides an overview of the first semester's core course, including objectives, learning outcomes, and practical laboratory exercises.

Uploaded by

Atif Rafiq
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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CHOICE BASED CREDIT SCHEME AT UNDER-GRADUATE LEVEL

COURSE STRUCTURE OF B. Sc. WITH CLINICAL BIOCHEMISTRY

SEM COURSE COURSE TITLE OF COURSE CREDITS


CODE TYPE THEORY PRACTICAL
I CLB120C DSC-1 BIOMOLECULES- METABOLISM AND 4 2
RELATED DISORDERS
II CLB220C DSC-2 CLINICAL IMMUNOLOGY AND 4 2
MICROBIOLOGY
III CLB320C DSC-3 CELL AND MOLECULAR BIOLOGY 4 2
IV CLB420C DSC-4 ORGAN FUNCTION AND RELATED 4 2
DISORDERS
VA CLB520DA DSE-1A CLINICAL BIOCHEMISTRY AND 4 2
OR ENZYMOLOGY
VB CLB520DB DSE-1B CLINICAL HAEMATOLOGY 4 2
VIA CLB620DA DSE-2A CLINICAL PATHOLOGY 4 2
OR CLB620DB DSE-2B BIO-ANALYTICAL TECHNIQUES 4 2
VIB
BACHELOR OF SCIENCE (GENERAL)
1st SEMESTER
DISCIPLINE SPECIFIC COURSE (CORE)
CLB120C: CLINICAL BIOCHEMISTRY: BIOMOLECULES- METABOLISM AND RELATED DISORDERS
CREDITS: THEORY – 4, PRACTICAL – 2
THEORY (4 CREDITS: 60 HOURS) MAXIMUM MARKS: 60, MINIMUM MARKS: 24

Objectives and Expected Learning Outcomes:


To acquaint the students with basic understanding of the structure and properties of macromolecules that
interact to maintain and perpetuate the living systems. Knowledge on the structure and function of different
biomolecules would enable the students to consolidate their focus on understanding various metabolic
pathways crucial for the sustenance of living systems.

UNIT-1 (15 Hours)


Chemistry of Carbohydrates: Definition, classification and structure of monosaccharides and important
polysaccharides; Metabolism of Carbohydrates - Glycolysis, Krebs cycle, Pentose phosphate pathway,
Gluconeogenesis, Glycogenesis, Glycogenolysis; Regulation of carbohydrate metabolism. Inborn errors of
carbohydrate metabolism

UNIT-2 (15 Hours)


Chemistry of Amino acids and Proteins: Structure, classification, properties and functions; Peptide bond,
secondary, tertiary, quaternary structure; Metabolism of Amino acid: Transamination, oxidative deamination,
Urea cycle, Degradation of amino acids like tryptophan, tyrosine, methionine cysteine Inborn errors of amino
acid metabolism

UNIT-3 (15 Hours)


Chemistry of Lipids: classification, structure, properties and functions of fatty acids, triacylglycerol,
phospholipids, sterols, lipids with special biological functions. Lipid metabolism: Biosynthesis and degradation
of saturated and unsaturated fatty acids, ketone bodies and cholesterol. Disorders of lipid metabolism

UNIT-4 (15 Hours)


Chemistry of Nucleic acids: structure and properties of purines and pyrimidine bases, nucleoside and
nucleotides, conformation of nucleic acids, stability of nucleic acid structure.Nucleic Acid metabolism:
Biosynthesis and degradation of purines and pyrimidines; Regulation of purines and pyrimidine biosynthesis,
Disorders of purine / Pyrimidine metabolism.

PRACTICAL (2 CREDITS: 60 Hours) MAXIMUM MARKS: 30, MINIMUM MARKS: 12

1) Preparation of standard Buffers and determination of pH of a solution.


2) Principle, working and maintenance of pH meter and Weighing balance
3) Biochemical calculations – Molarity, Molality, Normality, percent solution
4) Qualitative tests for Carbohydrates – Molisch, Fehling’s, Benedict’s test
5) Qualitative tests for Proteins and Amino acids
6) Quantitative estimation of carbohydrates
7) Quantitative estimation of proteins by Lowry’s method

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