Change the standards of exosomes
2F, 23, Sanun-ro 208beon-gil, Bundang-gu,
Seongnam-si, Gyeonggi-do, 13460, Rep. of Korea
Email :
[email protected] | Tel : +82 2 3288 8688
Exosome
Why is Exosome?
It’s because of its strong regeneration effect. This effect
is like an all all-around key that solves whitening, wrinkles,
wounds, and skin diseases.
EXOXE Effect
01 Anti-inflammatory 02 Antioxidant 03 Regenerative 04 Whitening
The most notable effect Exosomes help suppress Exosomes induce the Exosomes help improve skin
is the anti-inflammatory active oxygen, which is regeneration of damaged color by reducing melanin
effect. It is used as an harmful to the human body, cells through paracline production in cells.
alternative to steroids for with strong antioxidants, effects. It has a wide range of It quickly restores skin tone
dermatitis, inflammatory thereby improving wrinkles effects by colored with ultraviolet
acne, hair follicles, and atopic and preventing aging. rebuilding the skin barrier exposure.
dermatitis. and creating blood vessels..
Amniotic fluid exosome
“ “
Amniotic fluid-derived stem
Amniotic fluid-derived stem
cells are widely used in
cells are stem cells that
regenerative medicine, which
have the most differentiation
has multiple differentiation
potential and have no side
capabilities, does not cause
effects among human-derived
cancer, and can avoid ethical
stem cells*1
controversy*2
” ”
“ “
Unlike other stem cells,
amniotic fluid-derived stem
Amniotic fluid-derived stem
cells are ability to accelerate
“
Amniotic fluid-derived stem
cells have almost no cancer-
proliferation and movement of cells improve blood circulation
causing effect, which is a risk
dermal fibroblasts in the skin, by promoting the formation of
of stem cells, and rather used
causing wound healing and new blood vessels*5
for cancer treatment due to
skin regeneration*4
their anticancer action*3
”
” ”
1. Therapeutic Potential of Amniotic Fluid Derived Mesenchymal Stem ..: Ingenta Connect, 2. Amniotic fluid-derived stem cells in regenerative medicine research I Springer Link, 3. Potential
antitumor therapeutic strategies of human amniotic membrane and amniotic fluid-derived stem cells | Cancer Gene Therapy (nature.com), 4. Secretory Profiles and Wound Healing Effects of
Human Amniotic Fluid-Derived, Mesenchymal Stem Cells | Stem Cells and Development (liebertpub.com) 5. Xenografted human amniotic fluid-derived stem cell as a cell source in therapeutic
angiogenesis - ScienceDirect
10-1218101 Composition for hair growth promotion using fetal-derived mesenchymal stem cells in amniotic fluid
10-1371690 Prenatal-derived mesenchymal cord cultured under hypoxic conditions Mass production method of growth factors using gas
cells and mass of growth factors using fetal-derived mesenchymal stem cells in the skin regeneration composition 10-1119225 amniotic fluid
Production method 10-1078419 Composition for improving skin condition using fetal-derived mesenchymal stem cells in amniotic fluid
10-1334243 Fetal oil using wound stimulation Preparation method of culture medium leaf stem cells
HA Solution pure EXO
Why do we have
to use EXOXE?
Experience the real effects of exosomes, including 6 billion
particles,
the best exosomes, the best activator, and the perfect
treatment guide..
Which one is it?
There are eight different products from the top to the bottom,
and we conducted four experiments for each product by
changing the dilution level and arranged it horizontally. It is
the most reliable analysis method with comparative analysis
of exosomes. The results vary widely depending on the
product. Unlike advertisements, we were able to visually
check the substance of products with
poor quality.
Which line is EXOXE ™?
It was analyzed through the
Human CD63 Elisakit. 0.25 0.5 0.75 1
The darker the color,
Dilution concentration criteria (%)
the higher the exosome content.
6 Billion
particles
CD63 Exosome surface markers: red
dots on the screen
other Exosome EXOXE Exosome
particle
quantity
comparison
A B
The nanosite observation of exoxe shows
that high-quality particles of uniform
size and straight shape can be observed
and the number of particles is much
higher than that of A, B, and C.
C EXOXE
1600x size
particles
This image enables real-time
observation of the distribution of
particles through NanoSight equipment.
This allows you to see the size, number,
and distribution of the particles directly.
The picture above is a comparison
with many EXO-SOME products on the
market. The more particles there are A device called Nanosight guesses the size of particles and determines
and the more uniform it is, the better the the number of them through the movement of particles.
content and purity of the exosomes are. Particles of Exoxe were analyzed with this equipment.
Skin absorption P&K Skin Clinical Research Center / 2020.09.02~09.11
20 people with temporary individual differences between the whole body
Before use 30 minutes after use
Rate of change in skin absorption of test
products based on control product change
Before use 30 minutes after use rate (100%)
182% improvement
200
150
100
50
Before use 30 minutes after use 0
test control
product product
Before use 30 minutes after use
Intracellular
160
pro-collagen production (%)
collagen
120 150% increase in
P&K Skin Clinical
intracellular collagen
Research Center 80 based on
2020.10.19~11.20 0.05% concentration
20 people by concentration 40
Out-of-body test
0
con. 0.05
Intracellular Elastase Inhibition Assay
80
elastin
Elastase Inhibition (%)
39% reduction in
inhibitors 60
intracellular elastin
40 inhibitors based on
P&K Skin Clinical
0.05% concentration
Research Center
20
2020.10.19~11.20
20 people by concentration
0
Out-of-body test
3.13 0.05
Create
115
intracellular
HA production (% of Control)
Based on 0.05%
HA 110
concentration Create
105 intracellular HA
P&K Skin Clinical
160% increase
Research Center
100
2020.10.19~11.20
20 people by concentration
0
Out-of-body test
con. 0.05
DPPH radical scavenging activity (%)
Antioxidants Elastase Inhibition Assay
60
HUMAN SKIN CLINICAL 45
TEST CENTER causing aging Skin
2020.08.24 Antioxidant Testing oxidizing elements
30
(DPPHassay) After application over 55% Controlled
by concentration
Out-of-body test 15
0
10 100 Sample concentration (&, w/v)
Before & After
Pigmentation
3week later
Before After
Acne
3week later
Before After
Scar
3week later
Before After
Burn wound
3week later
Before After
Measure- ▶
ment of
hair volume
▶
Clinical Institution :
OATC Skin Clinical Trial Center
2021.05.10~06.07 / 22 candidates
▶
scalp, hair EXOXE™
products for ordinary people.
Before After
Exoxe holds 26 technology-related
patents and 5 overseas patents.
Contains large
amounts of
physiologically
active substances
EXOXE has 71 growth factors and
contains more than 1800 related
proteins
Thermo Exactive HybridTM Quadrupole-Orbitrap Mass Spectrometer
Repeat use 3 times
Hypoallergenic,
eye irritation,
tested
HUMAN SKIN CLINICAL
TEST CENTER
2022.09.20 ~ 09.22
