Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

1. A formula for a cough syrup contains 1/8 two teaspoonfuls of a pediatric cefadroxil a. 5
gr of codeine phosphate per teaspoonful. How suspension based on the body weight. If the b. 10 15. How many mL of Reglan injection
many grams of codeine phosphate should be child's weight is 18.3 lb, How many milligrams c. 15 (5mg/mL) should be given to a patient who is
used in preparing 2 pints of the cough syrup? of the drug is the child receiving in each dose? d. 30 eight months old? The usual dose of
a. 2.30 g a.250mg e. 20 metoclopramide HCl is 10 mg.
b. 6.43 g b.120 mg a. 1.0 mL
c. 1.54 g c.375 mg 11. How many milliliters of a 1:20 v/v solution b. 2.0 mL
d. 0.91 g d. 300 mg of methyl salicylate in alcohol can be made c. 0.1 mL
e. 1.03 e. 200 mg from 100 mL of 2% v/v solution? d. 0.2 mL
a. 25 e. 0.01 mL
2. How many grams of KSCN should be 6. A physician prescribes tetracycline b.38
used in compounding the following suspension for a patient to be taken in doses c.40 16. The usual dose of Tylenol® is 500 mg qid,
prescription? of two teaspoonfuls 4x a day for four days, d.30 prn fever. If Tylenol® is to be prescribed for a
Rx Potassium Thiocyanate and then one teaspoonful 4x a day for two e.20 two-month old baby, how many mL of
Aromatic elixir aa qs days. How many mL of the suspension should Tylenol® drops (80 mg/mL) should be given
Make a solution to contain 0.2 g?tsp be dispensed to provide the quantity for the 12. A physicians order for an IV infusion for a as a single dose to this patient?
Disp. 150 mL prescribed dosage regimen? patient weighing 110 lbs calls for a 0.25 mEq a. 0.08 mL
Sig: 5 mL in water daily a. 200 mL of KCl per kg of body weight to be added to b. 1.10 mL
a. 6 g b. 250 mL 500 mL of D5W. How many mL of a sterile c. 0.9 mL
b. 8 g c. 500mL solution containing 50 mEq of KCl per 10 mL d. 0.05 mL
c. 2.5 g d.120 mL should be used in preparing the infusion? e. 0.8 mL
d. 12.5 g e. 300 mL a. 10.0 mL
e. 7.25 b. 1.0 mL 16. Rx
7. If a potassium chloride elixir contains 40 c. 1.5 mL Keflex® caps 500mg
3. How many gr of dihydrocodeinone should milliequivalents of potassium ion in each 30 d. 2.5 mL Sig; 1 cap bid, 7 days
be used in compounding the following mL of elixir, how many mL will provide 15 e. 3.0 mL If the pharmacist has only 250 mg capsules
prescription? milliequivalents of potassium ion to the in the inventory, how many capsules should
Rx Dihydrocodeinone gr 1/12 /tsp patient? 13. A medication order for an IV infusion for a be given to the patient?
Hydriodic acid syrup a. 10.25 mL patient weighing 143 lbs calls for a 0.25 mEq a. 14
Cherry syrup aa fl oz Iii b. 15.00 mL of ammonium chloride per kg body weight to b. 7
Sig: Tsp every 2 hr for cough c. 11.25 mL be added to 500 mL 5% dextrose injection. c. 21
a. 6 d.25.00mL How many mL of a sterile solution containing d. 28
b. 3 e. 10.75 mL 100 mEq of ammonium chloride per 25 mL e. 24
c. 12 should be used in preparing the infusion?
d. 1.5 8. What is the percentage of alcohol in the a. 6.2 mL 17. If two pints of a guaifenesin elixir is
e. 4 following precription? b. 4.1 mL present in the inventory, how many 4-fluid
Rx Chloroform spirit 50.0 mL (90% alcohol) c. 8.0 mL ounces prescription can be filled?
4. A patient has been instructed to take 15 Aromatic elixir 150.0 mL (21% alcohol) d. 9.8 mL a. 12
mL of Vistarel® (hydroxyzine pamoate) oral Terpin hydrate elixir 300.0 mL e. 5.3 mL b. 10
suspension every six hours four doses daily. (45% alcohol) c. 5
How many days will two fluidounce bottles of Sig. 5 mL for cough 14. Prochlorperazine is prescribed for a child d. 8
suspension last? a. 42.3 % whose date of birth is 05/21/2001. If the usual e. 6
a. 10 b.56.75% adult dose is 5 mg, how many mg would be
b. 5 c.18.2% administered to the child? The prescription is 18. An IV flow rate is set at 48gtt/mL. The
c.11 d. 38.7% dated 01/01/2005. infusion set has a drop factor of 15gtt/mL.
d.6 e.39.7% a. 0.625 mg How many mL of IV fluid will be infused in 8
e.8 b. 0.820 mg hrs?
10. If 5 mL of a 20% w/v aqueous solution of c. 0.250 mg a. 1536 mL
5. The pediatric dose of cefadroxil is 30 furosemide is diluted to 10 mL, what will be d. 0.500 mg b. 2395 mL
mg/kg/day. A child is receiving a daily dose of the final strength of furosemide? e. 0.725 mg c. 1050 mL
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

d. 950 ml 24. How many apothecary ounces are present a. 2 33. If a pharmacist dispenses cephalexin 250
in lbs iiss? b. 1 mg capsules for the prescription below, what
19. What is the percentage (w/w) of coal tar in a. 30 c. 1/2 directions should be provided to the patient?
the finished product in when 10 g of coal tar is b. 42 d. 1/4 Rx
mixed with 200 g of a 5% coal tar ointment? c. 16 e. 1/3 Cephalexin capsules 500 mg
a. 4 d. 9.5 Sig; 1 cap tid, 10 days
b. 6.8 e. 22 29. Rx a. 2 caps 3x a day for 10 days
c.9.5 Atropine sulfate 0.2 mg b. 3 caps 2x a day for 5 days
d. 11.0 25. Zovirax® tablets, containing the antiviral Sig; Administer IM c. 2 caps 4x a day for 8 days
drug, acyclovir, are given in a dose of 80 If the available atropine vial reads gr 1/150 per d. 3 caps once a day for 15 days
20. A physician ordered: “Benadryl® 50 mg mg/kg for 5 days for treating chickenpox. If the mL, how many mL of the injection should be e. 2 caps 2x a day for 14 days
PO h.s. p.r.n.” If the available Benadryl® patient weighs 120 lbs, how many ounce(s) of administered?
(diphenydramine HCl) elixir contains 2.5 mg acyclovir would the patient consume if he has a. 1.20 34. Spironolactone tablets are available in 25
drug in each mL, how many teaspoons will be to take the full dose prescribed? b. 0.75 mg strength, but a drug orders comes for 150
administered to the patient? a. 1.3 c. 1.43 mg dose. How many tablets should be
a. 4 b.0.73 d. 0.465 dispensed to last for 5 days?
b. 6 c. 16 e. 1.72 a. 6
c. 2 d. 9.5 b. 12
d. 5 e. 3.5 30. A medication order calls for Prostigmin® c. 20
e. 3 0.25 mg IM. The only supply of Prostigmin® is d. 30
26. If a physician orders "Lanoxin® 0.25 mg 1:200 solutions. How many mL of this solution e. 25
21. Fer-in-sol® drops contain 75 mg ferrous p.o. q.d.", how many mL of Lanoxin® (digoxin) would contain 0.25 mg?
sulfate 0.60 mL of the solution. If a pharmacist elixir containing 50 mcg of digoxin per mL a. 0.05 mL 35. Calculate the (w/w) of coal tar in the
dispensed 60 mL of the solution, how many should be used? b. 0.75 finished product when 8 grams of coal tar is
grams of ferrous sulfate were dispensed?' c. 1.43 mixed with 120 grams of a 4% coal tar
a. 10 a. 15 mL d. 0.465 ointment.
b. 7.5 b. 10 mL e.1.72 a.10
c. 15 c. 8 mL b. 15
d. 20 d. 5 mL 31. What is the percentage (w/w) of c. 20
e. 9 e. 3 mL hydrocortisone in the finished product when d. 30
50 mg of hydrocortisone is mixed with 10 e. 25
22. If a patient needs one teaspoonful of 27. A patient has been instructed to take grams of Cortril® ointment containing 1%
Amoxil® oral liquid 3x a day for seven days, Vistarel® (hydroxyzine pamoate) oral hydrocortisone? 36. If a 10 mL vial of insulin contains 200 units
how many fluidounces of medication should suspension every four hours for four doses a. 0.05 mL of insulin per milliliter, and a patient is required
the pharmacist dispense? daily. How many days will a 6 -fluidounce b. 0.5 mL to receive 20 units twice daily, how many days
a. 12 bottle of the suspension last? c. 5 mL will the product last the patient?
b. 8 a. 2 d. 0.25 mL a. 20 days
c. 6 b. 4.5 e. 0.005 mL b. 30 days
d. 3.5 c. 7 c. 35 days
e. 7 d. 12 32. What is the percentage of ZnO in an d. 50 days
e. 6 ointment prepared by mixing 200 grams of an e. 45 days
23. How many liters of 2% w/v Iodine tincture 8% ZnO ointment, 150 grams of a 12% ZnO
can be made from 78 g of iodine? 28. Rx ointment, and 300 grams of white petrolatum 37. A patients receives 30 mL of heparin
a. 3.9 Phenergan tablets 12.5 mg (diluent)? every hour. If there are 40 units in each
b. 6.2 Dispense 14 tablets a. 2.3% milliliter, how many units does the patient
c. 4.8 Sig; q hs b. 4.5% receive in 24 hours?
d. 12 If the pharmacist dispensed 25 mg tablets of c. 7.8% a.30, 200
e. 4.6 phenergan, how many tablets should the d. 5.23% b.28, 000
patient take at bedtime? e. 2.3 % c. 12,440
d. 21,880
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

e. 14, 250 43. In the calibration of a medical dropper, 2 48. Calculate the specific volume of a syrup if
mL of a pediatric drop solution was found to 20 mL of it weighs 35 grams. 54. If 200 mg of propylhexedrine, a liquid
38. How many mL of a 1:500 v/v solution of give 48 drops. If it is desired to administer 0.3 a. 1.75 having a specific gravity of 0.85, are used in a
methyl salicylate in alcohol can be made from mL of the medication to a baby, approximately b. 0.57 single nasal inhaler, how many millimeters of
100 mL of 5 % v/v solution? how many drops should be given? c. 1.86 drug would be used in the manufacturing of
a. 2 500 a. 1 d. 0.72 1000 inhalers?
b. 250 b. 3 e. 0.76 a. 294
c. 5000 c. 5 b. 308
d. 1500 d. 8 49. What is the specific volume of sulphuric c. 78
e. 3500 e. 2 acid having a specific gravity of 1.826? d. 402
a. 0.548 e. 113
39. Calculate the IV flow rate for 500 mL D5W 44. If an injectable solution contains 25 mcg of b. 1.800
to run for 8 hours. The drop factor is 60 a drug substance in each 0.5 mL, how many c. 0.431 55. The inhalant dose of amyl nitrate is 0.25
gtt/mL. mL will be required to provide a patient with d. 2.135 mL, express the dose in minims.
a. 70 gtts/min 0.25 mg of the drug substance? e. 0.673 a. 3.50
b. 65 gtts/min a. 15 mL b. 4.06
c. 63 gtts/min b. 10 mL 50. What is the weight of 3.5 liters of alcohol c. 2.55
d. 54 gtts/min c. 5 mL having a specific gravity of 0.835? d. 0.88
e. 72 gtts/min d. 1 mL a. 4.19 g e. 3.33
e. 20 mL b. 2922.5
40. If a vial of gentamycin contains 80 mg of c. 2.92 56. Given a solution of potassium
drug in 2 mL, how many mcg of the drug are 45. A certain elixir contains 0.325 g of the d. 3102 g permanganate prepared by dissolving twenty
present in 0.02 mL active ingredient per teaspoonful. At PhP e.454.3 0.2 g tablets in enough purified water to make
a. 800 15.35 per lb, what is the cost (PhP) of the two liters of resulting solution, what is the
b. 350 active ingredient needed to make one gallon 51. How many grams would 1 pint of HCl percentage strength of the solution?
c.26 of the elixir? weigh (sp. gr. 1.16)? a. 2.0 %
d. 655 a. 6.41 a. 345 b. 4.0%
e. 260 b. 8.32 b. 675 c. 0.2 %
c. 24.06 c. 549 d. 0.4%
41. Atenolol is available in strength of 50 mg. d. 12.05 d. 980 e. 20.0%
If a prescription is written for 100 mg daily for e. 9.36 e. 560
three weeks as directed, how many tablets 57. In problem number 56, what is the ratio
should be dispensed? 46. If a 500 mL of ferric chloride solution 52. What is the volume (in millimeters) of 2 kg strength of KMnO4 solution?
a. 20 weighs 650 g, what is its specific gravity? of sulfuric acid with a specific gravity of 1.83? a. 1:500
b. 42 a. 1.3 a. 1093 b. 1 :50
c. 21 b. 0.7692 b. 2095 c. 1:250
d. 60 c. 1.45 c. 1205 d. 1: 20
e.45 d. 0.8451 d.1830 e. 1:350
e. 0.93 e.1003
42. If Lactulose Syrup USP contains 10 g 58. Express a patient's uric acid level of 6.0
lactulose in 15 mL of the syrup, how many mL 47. What is the density of a metal, 10 mL of 53. If 500 mL of mineral oil is used to prepare mg/dL in terms of mg%.
would provide the equivalent of 1.33 g of which weighs 5450 mg? a liter of mineral oil emulsion, how many a. 12
lactulose? a. 1.106 grams of oil having a specific gravity of 0.87 b. 6
a. 2 b. 0.670 would be used in the preparation of 1 gallon of c.0.6
b. 5 c. 0.545 emulsion? d. 60
c. 10 d. 10.5 a. 1780.1 e. 16
d. 6 e. 0.626 b. 1646.5
e. 4 c. 245.30 59. If a 10 mL serum ampule is determined to
d. 1100.4 contain 9 mg of glucose, express the
e. 1546.5 concentration of glucose as mg%.
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

a. 90 65. What is the concentration of 0.04% (w/v) a. 0.5 77. The cost of 100 antacid tablets is PhP
b. 9 NaCl solution in ratio strength? b. 1.8 68.50. What should be the selling price per
c. 18 a. 1:2500 c. 20 hundred tablets to yield a 40% gross profit on
d. 6 b. 1:166.67 d. 0.05 the selling price?
e. 0.9 c. 1:250 e. 2.25 a. 114
d. 1:400 b. 210
60. What is the proof strength of a 40% e. 1: 225 72. Calculate the weight in grams of two pints c. 75
alcohol? of syrup if its specific gravity is 0.975. d. 88
a. 40 66. What is the % w/w concentration of a 10% a. 970.26 g e. 107
b. 60 w/v cough syrup having a specific gravity of b. 498.10 g
c. 75 1.120? c. 922.35 g
d. 80 a. 8.93% d. 670.05 g 78. A bottle of (30's ) of analgesic tablet sold
e. 65 b. 11.20% e. 899. 45 g at PhP 75.00, thereby yielding a gross profit of
c. 12.50% 30% on the cost. What was the cost of the
61. How many proof gallons does 20 wine d. 7.15% 73. If five gallons of lotion contains one pound bottle of tablets?
gallons of a 15% v/v alcohol measure? e. 9.85% of talc, what is the percentage strength? a. 62.35
a. 6 a. 2.4 % b. 57.70
b. 12 67. If a commercially available insulin b. 6.7% c.68.50
c. 3 preparation contains 2 ppm of proinsulin, how c. 8.3 % d. 52.00
d.20 many grams of pro insulin would be contained d. 10.5 %
e. 4 in a 10 mL vial of insulin? e. 3.6% 79. A prescription item costs a pharmacist
a. 0.00003 PhP 45.00. Upon mark up of 35% on the cost
62. A glucometer shows that a patient's blood b. 0.004 74. What is the % w/v concentration of a plus a professional fee of PhP 30.00, what
serum contains 135mg% glucose. Express c. 0.0007 solution made by mixing 35 g of main would be the price of the dispensed
this value in % w/v. d. 0.0002 ingredients in 500 g of vehicle (sp. gr. 1. prescription?
a. 0.135% e. 0.0006 2000)? a. 85.50
b. 1.35% a. 1.25% b. 92.25
c. 0.27% 68. Express the concentration of aromatic b. 7.75% c. 78.50
d. 13.5% water in a ratio strength prepared by mixing 2 c. 16.2% d. 90.75
e. 3.15% mL of aromatic oil in 450 mL distilled water. d. 8.4 % e. 88.50
a. 1:200 e. 8.3 %
63. The fluoride concentration in drinking b. 1:312 80. How many chloramphenicol capsules,
water is 0.5 ppm. Express this concentration c. 1: 227 75. How many proof gallons are contained in each 250 mg are needed to provide 25 mg per
in percent. d. 1:225 8 wine gallons of 75% (v/v) alcohol? kg per day for 1 week for a person weighing
a. 0.005% e. 1: 335 a. 20 175 lbs?
b. 0.00005% b. 16 a. 43
c. 5% 70. Calculate the ratio strength of a sulfur c. 12 b.38
d. 0.5 % ointment which contains two oz. of sulfur in d. 10 c. 65
e.0.05% thirty kilograms of ointment. e. 15 d. 56
a. 1:1058 e. 72
64. If 600 mg of sodium chloride is dissolved b. 1: 2030 76. A pharmaceutical manufacturer has 4500
in enough water to make three pints of NaCl c. 1: 3065 gallons of 95% (v/v) alcohol. How many proof 81. How many grams of sodium bicarbonate
solution, what is its concentration in % w/v? d. 1: 1150 gallons are represented by this quantity? (MW= 84g/mole) should be used in preparing
a. 6% e. 1: 1008 a. 8050 a liter of solution which is to contain 8 mEq of
b. 4% b. 9250 sodium bicarbonate in each 10 mL?
c. 0.04% 71. What is the percent strength of a 1:2000 c. 1450 a. 67.2 g
d. 0.6% potassium chloride solution? d. 8550 b. 57.1 g
e. 40% e. 8250 c. 73 g
d. 90 g
e. 52.4 g
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

Ipecac fluidextract 70 mL a. 63%

82. How many grams of KCl (MW=74.54 Glycerin 100 mL b. 38% 98. If three pounds of a substance would be
g/mole) should be used in making a liter of Syrup qs 1000 mL c. 21% used in preparing 2000 tablets, how many
solution containing 5 mEq of potassium per a. 100 d. 34% milligrams are represented in each tablet?
mL? b. 105 e. 57% a. 681
a. 372.7 g c. 90 b. 725
b. 186.35 g d. 120 93. How many millilitres of a 50% w/v solution c. 850
c. 435 g e. 80 should be mixed with 2175 mL of a 10% w/v d. 1250
d. 74.54 g solution to make a 20% w/v solution? e. 632
e. 433.3 g 88. In what portion should 10% and 20% coal a. 800 mL
tar ointments be mixed to prepare a 5% b.615 mL 99. If the dose of the drug is 1/16 grains, how
83. Ether has a specific gravity of 0.72. How ointment? c.415 mL many doses are contained in two drams?
many milliliters will 60 grams measure? a. 3 parts/5parts d.725 mL a. 2045
a. 72 b. 5 parts/3 parts e. 650 mL b. 1920
b. 43 c. 2 parts/ 6 parts c. 1560
c. 83 d. 1 part/ 3 parts 94. Calculate the number of mL of water d. 980
d. 96 e. 5 parts/ 2 parts needed to be added to a mixture of 700 mL of e. 1430
e. 91 55% v/v alcoholic solution and enough 20%
89. What is the percentage strength of a 1: v/v alcoholic solution to make 1000 mL if the 100. How many mEq of Na+ are in 200 mL
84. What bis the % w/w of a 75% preparation ( 10,000 potassium permanganate solution? final solution is to be 40% alcoholic solution. NSS (MW= 58.5)?
sp. gr. 1.085)? a. 0.01% a. 75 mL a. 15.4
a. 78 b. 1.10% b. 300 mL b. 30.8
b. 69 c. 20% c. 55 mL c. 58.5
c. 81 d. 0.5% d. 225 mL d. 9.0
d. 62 e. 10.0% e. 125 mL e. 45.2
e. 74
90. Calculate the ratio strength of a mixture 95. If a dose of 1/600 gr is prescribed, its 101. A 500 mL infusion bottle contains 2.0
85. The patient is to take 1 teaspoonful of prepared by mixing 2 oz of ZnO in one equivalent dose in microgram is: mEq Calcium per mL. How much calcium (At.
medication bid for 1 week. How many mL of kilogram white petrolatum. a. 10 Wt. Ca=40) in grams does it contain?
the medication should the patient buy? a. 1:500 b.100 a. 10
a. 60 mL b. 1: 35.78 c.120 b. 40
b. 70 mL c. 1: 18.62 d. 60 c.30
c. 120 mL d. 1: 23.97 e.80 d. 20
d. 150 mL e. 1:36.78 e. 50
e. 80 mL 96. A household measure of 1 wineglass is
91. How many liters of a 95% sulfuric acid equivalent to: 102. Given the following prescription:
86. How many 2-fluid ounce bottles of a cough having a specific gravity of 1.82 should be a. 2 fluidounces Rx
syrup can be obtained from one gallon of the used in preparing three liters of 10% sulfuric b. 4 fluidounces V-Cillin® K 250 mg/tablet
cough syrup? acid? c. 8 fluid drams Disp. # 28
a. 50 a. 0.17 d. 4 fluid drams Sig: 1 tab q 6h until finished
b. 45 b. 2.1 e. 8 fluidounces How many days will the medication last?
c. 64 c. 0.32 a. 5
d. 27 d. 0.54 97. How many teaspoonfuls would be b. 10
e. 56 e. 0.22 prescribed in each dose of an elixir if 6 fluid c. 7
ounces contained 36 doses? d. 6
87. From the following Ipecac Syrup, calculate 92. What is the strength of sodium chloride a. 4 e. 8
the amount of Ipecac needed to prepare solution obtained by evaporating 550 grams of b. 2
enough syrup to fill one hundred 15-mL a 12% solution to a final weight of 150 grams? c. 1 103. How many mg of the active ingredient is
prescription bottles: d. 5 present in this preparation?
e. 3
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

Rx Thiamne HCl 10 mg a. 23 g of Tween40 and 46.7 g of Span20

Neosynephrine® 2.5% Calcium carbonate 100 mg b. 17.5 g of Tween40 and 52.5 g of Span20 117. What is the dose for a child whose body
10 mL M ft. Cap DTD #12 c. 30.0 of Tween40 and 40.0 g of Span20 surface area is 0.64m2 if the adult dose is
Sig: I gtt os tid Sig: i cap qid for nausea d. 40.0 g of Tween40 and 30.0 g of Span20 a. 208 mg
a. 25 How many mg of dimenhydrinate is needed to e. 33.0 g of Tween40 and 25.0 g of Span20 b. 120 mg
b. 250 compound this prescription? c. 31 mg
c. 2.5 a.1400 112. Rx d. 162 mg
d. 0.25 b.550 Atropine 1%# e. 140 mg
e. 2500 c.360 Boric acid q.s.
d.405 Purified water ad 50 mL 118. What is the cost of 15.0 kg of glycerine
104. Rx e. 300 Make Isotonic solution (sp. Gr. =1.25) if it is sold at 175.00 per kg?
Neosynephrine® 2.5% Sodium chloride equivalent (E) a. 4394.75
10 mL 108. Pediaprofen® pediatric suspension Atropine Sulfate =0.12 b.4943.75
Sig: I gtt os tid contains 80 mg ibuprofen in 5 mL of Boric Acid= 0.52 c.4439.75
If the dropper to be used in the above suspension. While taking 2.5 mL of this How many grams of boric acid ahould d.4444.95
prescription is calibrated to deliver 20 gtts per medication, the patient spilled 1 mL of the be used in compounding the prescription? e.4344.75
mL, how many doses are contained in the suspension. How many milligrams of a. 1.33 g
preparation? ibuprofen did the patient spill? b. 0.75 g 119. A prescription calls for 1500 mL of D5W
a. 20 a. 24.0 c. 0.13 g to be administered over a 10 hour period
b. 50 b. 37.0 d. 0.91 g using a which delivers 15 drops/mL, what is
c. 300 c.30.0 e. 0.80 g the rate in drops per minute?
d. 200 d.40.0 a. 12.50 drops/min
e. 150 e.29.0 113. What is the dissociation factor (1) of b. 35 drops/min
Benzalkonium chloride? c. 40 drops/min
105. Rx 109. The cost of an alcohol is P250.00 per a. 0.19 d. 42.5 drops/min
Corticosporin otic solution proof gallon. What is the cost of 10 wine b.0.18 e. 45 drops/min
15 mL gallons of alcohol marked “190 proof”? c. 0.17
Sig: iv gtt ad qid a. P4500.00 d. 0.16 120. 250 mg of Amoxicillin is added to 500 mL
If 1 mL. of the solution contains 15 gtts, how b. P4750.00 e.0.20 of D5W and the rate of administration is 125
many days will the medication last? c. P5000.00 mg per hour, what will be the rate of flow in
a. 7 d. P5250.00 114.What is the Sodium Chloride equivalent drops per minute if the infusion set delivers 15
b. 14 e. P4250.00 (E) of Benzalkonium chloride? drops/min?
c. 15 a. 0.19 a. 12.50 drops/min
d. 20 110. A drum contains 60 proof gallons of 40% b. 0.18 b. 13.00 drops/min
e. 12 alcohol. How much would 3 drums cost if the c. 0.17 c. 13.50 drops/min
alcohol is sold at P60.00 per wine gallon? d. 0.16 d. 14.00 drops/min
106. Rx a.P14000.00 e. 0.20 e.14.50 drops/min
Tagamet 300 mg b.P15000.00
Sig : i bid, 15 days c.P14500.00 115. Convert 37˚Celsius to Farenheit 121. What is the daily dose of Amoxicillin for
How many tablets should the patient d.P13500.00 a. 96.8 the last 2 days?
buy to complete the medication? e.13000.00 b. 86.9 a. 1250 mg
a. 30 c.98.6 b. 500 mg
b. 45 111. A formula for an ointment requires 70g of d.69.8 c, 750 mg
c. 15 an emulsifier blend consisting of Tween40 and d. 1000 mg
d. 50 Span20. If the required HLB is 11.6,how many 116. Convert 212˚F or farenheit to centigrade e. 950 mg
e. 35 grams of each emulsifier should be used in a.100
preparing the ointment? HLB of Span20= 8.6, b.95 122. If the dropper calibrates 20 drops/mL,
107. Rx Tween 40=15.6 c.90 how many drops should be administered?
Dimenhydrinate d.105
Pantothenic acid aa 30 mg e.110
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

a. 4 drops d.11.31 a. 8.56 d. 15

b. 8 drops e.13.11 b. 7.19 e. 18
c. 6 drops c. 10.24
d. 5 drops 128. A person is to receive 4 mEq of sodium d. 9.26 138. A prescription calls for 325 mg of Aspirin.
e. 7 drops chloride per kg body weight. If the person e. 8.00 After weighing this amount, the pharmacist
weighs 165 lbs., how many mL of Normal decided to check by weighing again. Now he
123. How many pints of high alcoholic elixir is Saline Solution should be administered? 133. How many mL of Hydrochloric Acid USP finds he has only 315 mg. What is the
required to prepare the same amount of elixir? (NaCl MW= 58.5 g/mole) (37% w/w; sp. gr.= 1.8) are needed to prepare percentage?
a. 5.9 a.1900 mL 150 mL of dilute Hydrochloric Acid (10.0% a. 3.10 %
b.3.4 b.1800 mL w/v)? b. 3.11 %
c.7.2 c. 2000 mL a. 22.5 mL c. 3.06 %
d.4.7 d.1950 mL b. 34.3 mL d. 3.08 %
e. 6.4 e. 1750 mL c. 42.1 mL e. 3.00 %
d. 27.4 mL
124. What is the percentage (w/v) of dectrose 129. A physician prescribes 10 million units of e. 25.2 mL 139. What is the dose for A 38.5 lb child if the
in a mixture of 6000 mL of 5% (w/v) dextrose Benzyl Penicillin Na daily for 1 week. If 1 ug of average adult dose of a drug is 125 mg?
solution and 750 mL of 50% (w/v) dextrose Benzyl Penicillin Na equals 1.6 unit, how a. 3.21 mg
solution? many tablets each containing 500 mg will 134. What is the HLB of a mixture of 30.0% of b. 32.1 mg
a. 1.0% provide the benzyl penicillin Na for the Tween80 and 70.0% of Span80? HLB of c. 0.32 mg
b. 10.0% prescribed dosage regimen? Span80=4.3; Tween 80=15.0 d. 321.0 mg
c. 1.5% a. 17.5 tablets a. 7.5 e. 30.21 mg
d. 15.0% b. 12.5 tablets b. 8.7
e. 10.1% c. 15 tablets c. 10.1 140. What is the dose for a ten-month old
d. 10 tablets d. 6.6 baby if the average adult dose is 250 mg?
125. How many grains of potassium e. 14 tablets e. 6.9 a. 16.55 mg
permanganate should be dissolve din 1.5 b. 12.12 mg
pints of water to make 7.5% (w/v) solution? 130. A physician prescribed 225 U of insulin to 135. How many 96.0% of sulfuric acid having c. 18.77 mg
a.818.9 be added to 250 mL of D5W in treating a a specific gravity of 1.54 is required to make d. 16.67 mg
b. 818.6 patient with severe diabetic acidosis. How 500 mL of diluted sulfuric acid (10.0% w/v)? e. 17. 11 mg
c. 820.7 much U-100 insulin should be used? a. 27.8 mL
d. 808.7 a. 0.225 mL b. 26.4 mL 141. A Tetracycline Syrup is preserved with
e. 881.1 b. 2.25 mL c. 23.6 mL 0.08% (w/v) of methylparaben 0.02% (w/v) of
c. 22.5 mL d. 28.3 mL Propylparaben and 0.10 %(w/v) of Sodium
126. How much NaCl should be used in d. 225.0 mL e. 24.6 mL Metabisultfite. Express these concentrations
compounding the prescription? e. 25.2 mL in ratio strengths.
a.0. 330 g 136. Mr. Juan Dela Cruz adds 125 mL of a. 1:1000, 1: 5000, 1:1250
b.0. 320 g 131. The dissociation constant of Salicylic Strong Iodine Solution USP (7.5 % w/v) to a b. 1:1250, 1:5000, 1:1000
c. 0.325 g Acid is 6.30x10(-5) at 25°C. Calculate the pka liter of Sterile Water for Irrigation. What is the c. 1:5000, 1: 2000, 1: 2500
d. 0.335 g value. percent (w/v) of Iodine? d. 1: 1250, 1: 5000, 1: 1250
e. 0.352 g a. 4.89 a. 0.90 % e. 1: 1750, 1: 1000, 1: 1500
b.5.35 b. 0.83 %
127. A pharmacist adds 20 nmL of Calcium c. 4.76 c. 0.94% 142. If 198g of sodium chloride are dissolved
Chloride Injection labeled 4 mEq/ mL to a 500 d. 4.20 d. 0.75% in 1000 mL of water, what is the % strength
mL bottle of D5W injection. What is the e. 4.30 e. 0.99% (w/w) of the solution?
concentration of calcium chloride expressed a.16.5 %
as mg/mL in the final mixture? (CaCl.H20 132. What is the pH of a buffer solution 137. How many proof gallons are contained in b. 11.5 %
MW=147) prepared with 0.5 M Sodium Benzoate and 10 wine gallons of a 75.0% (v/v) alcohol? c. 15.6 %
a. 12.13 0.05 M Benzoic Acid is 6.4x 10(-7) at 25°C? a. 12 d. 15.5 %
b. 13.12 b. 5 e. 6.5%
c.11.23 c. 10
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

143. If 120 g of Chloroform measures 150 mL, 148. How many grams of white wax shoukld 153. A physician advises an adult patient to
what is its specific volume? be added to 250g of a 25% Zinc Oxide take a children's aspirin tablet (81 mg of 158. How many mL of 1:300 (w/v) stocks
a. 2.25 Ointment to make 5% ointment? aspirin per tab) daily as a precaution against solution should be used to make five liters of a
b. 1.50 a. 100 g heart attack,. Instead, the patient decides to 1:2000 (w/v) solution?
c. 1.25 b. 500 g cut 5-grain aspirin tablet into dosage units. a. 758
d. 0.95 c. 1000 g How many doses could be obtained from each b. 890
e. 1.5 d. 1250 g 5-grain tablet? c. 623
e. 10000g a. 4 d. 920
144. Five pints of Benzene weighs 2. 79 kg. b.6 e. 854
Compute its specific gravity. 149. An intravenous solution containing 100 c. 8
a. 3.180 mg of a drug substance in each 250 mL is to d. 10 159. A topical solution contains 35% (w/w) of
b. 2.180 be administered at the rate of 150 mcg of drug e. 7 erythromycin. Express the concentration of
c. 1. 180 per minute. How many mL of the solution erythromycin in terms of milligrams per
d. 0.180 would have been given in an hour? 154. Two (2) lbs of a fungicidal ointment milliliter (mg/mL).
e. 2.020 a. 2.25 mL contains 12.00 g of undecylenic acid. a. 225
b. 6.0 mL Calculate the percentage (w/w) of the b. 500
145. A glass plummet weighs 16.60 in the air, c. 3.75 mL undecylenic acid in the ointment. c. 350
13.65 when immersed in water and 11.20 g d. 9.10 ml a. 6.8 d. 400
when immersed in mineral oil. What is the e. 3.25 mL b. 2.0 e. 375
specific gravity of mineral oil? c. 1.32
a. 1.138 150. A vial of tobramycin sulfate contains 100 d. 3.45 160. Hepatitis B Virus Vaccine Inactivated is
b. 8.31 mg of drug in 2 mL of injection, how many e. 4.7 inactivated with 1:4000 (w/v) of formalin.
c. 0.381 milliliters of the injection should be Express this as percentage strength.
d. 0.831 administered to obtain? 155. A liniment contains 12% (v/v) of methyl a. 0.25
e. 0.038 a. 0.006 mL salicylate. How many milliliters of the liniment b. 0.025
b. 0.04 mL can be made from two pints of methyl c. 0.04
146. Franco Ravales has been instructed to c. 0. 03 mL salicylate? d. 0.004
take 15 mL of Cloxacillin oral suspension d. 0.004 mL a. 140.50 mL e. 0.4
every other hour for four doses daily. How e. 4.0 mL b. 170. 28 mL
many days will two 12-fluidounce bottles of c. 65.08 mL 161. The usual IM dose of kanamycin sulfate
the suspension last? 151. A drug substance has been shown to be d. 189.21 mL is the equivalent of 7.5 mg kanamycin per kg
a. 12 days embryotoxic in rats at the dose of 30 e. 200.00 mL of body weight. How many milliliters of
b. 13 days mg/kg/day. Express the dose on the basis of kanamycin sulfate injection containing the
c. 10 days mcg/lb/day. 156. Express three mg of active ingredients in equivalent of 250 mg kanamycin per mL
d. 15 days a. 13620 two mL of solutions as ratio strength. should be given to a person weighing 170 lb?
e. 14 days b.8760 a. 1:667 a. 4.1
c. 11245 b. 1:458 b. 0.9
147. Baby De la Vega weighing 25 lbs. is to d. 14900 c. 1:920 c. 2.3
receive 4 mg of Phenytoin per kg body weight e. 14325 d. 1:700 d. 3.4
daily as an anticonvulsant, How many e. 1:554 e. 3.6
pediatric phenytoin suspension should 152. If one fluid dram of a cough syrup
containing 30 mg /5 mL should the child contains 15 grains of sodium citarate, how 157. What is the % concentration of 162. The adult dose of a liquid medication is
receive? many milligrams are contained in 5 mL? cholesterol in a patient's blood serum if the 0.15 mL per kg of body weight to be
a. 7.6 mL a. 320 mg cholesterol level is determined to be 280 administered as a single dose. How many
b. 6.6 mL b. 1025 mg mg%? teaspoonfuls should be administered to a
c. 5.6 mL c.972 mg a. 0.43% person weighing 225 lb?
d. 1.6 mL d. 675 mg b. 0.65% a. 3
e. 8.6 mL e. 873 mg c. 0.28% b. 5
d. 0.51% c. 2
e. 0.34% d. 1
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

e. 4 d. 4 172. Corticotropin injection is available in a e. 25

e. 12 concentration of 40 units per mL. How many
163. How many grams of fluorouracil will a mL of the injection should be administered to 177. A disinfectant concentrate for surgical
160-lb patient receive in six (6) successive 168. If Efudex cream contains 5% fluorouracil, provide 0.5 unit per kg for a child weighing 70 instruments contains 8% (w/v) of a quaternary
days at a dosage rate of 12 mg/kg/day? calculate the percentage (w/w) of fluorouracil lbs. ammonium compound. What is the
a. 5.24 in the prescription? a. 0.4 mL percentage strength of a solution resulting
b. 6.10 Fluorouracil 20g b. 2.5 mL from the addition of 60 mL of the concentrate
c. 2.35 Efudex cream 60 g c. 0.8 mL to 2 liters of water?
d. 1.95 White Petrolatum ad 300g d. 1.1 mL a. 0.02%
e. 5.45 Sig. Apply as directed e. 0.6 mL b. 0.5%
a. 7.67% c. 0.35%
164. The loading dose of chloramphenicol in b. 9.20% 173. A physician prescribes 60 mL of d. 0.1%
neonates is 20 mg/kg of body weight. If c. 10.20% phenoxymethyl penicillin for oral suspension e. 0.25%
neonates weighed 7 lbs, what is the loading d. 5.56% containing 5,000,000 units. How many
dose? e. 6.58% penicillin units will be represented in each 178. A physician advises an adult patient to
a. 73 teaspoonful dose of the prepared suspension? take Amoxicillin Oral Suspension (250 mg/ 5
b. 64 169. A pediatric product is formulated to a. 550, 200 U mL) in doses of 2 teaspoonfuls 4x a day for 4
c. 2.35 contain 150 mg of erythromycin ethylsuccinate b. 326, 000 U days, and then 1 teaspoonful 4x a day for 2
d. 1.95 in each dropperful (2.5 mL) of the product. c. 600, 300 U days . How many milliliters of suspension
e. 76 How many grams of erythromycin d. 417,000 U should be dispensed to provide the quantity
ethylsuccinate would be required to prepare e. 250,000 U for the prescribed dosage regimen?
165. How many milliliters of an injection 400 bottles each containing 50 mL of the a. 250 mL
containing 25 mg of gentamicin in each 2 mL preparation? 174. If 10 mcg of ergocalciferol represents b. 300 mL
should be used in filling a medication order a.750 g 500 units of vitamin D, how many 1.25-mg c. 150 mL
calling for 3.5 mg gentamicin to be b. 1150 g ergocalciferol capsules will provide a dose of d. 200 mL
administered intramuscularly? c. 1000 g 300,000 units vit D e. 275 mL
a. 0.40 d. 1200 g a. 3.2
b. 0.50 e. 675 g b. 5.9 179. A pediatrician prescribed 25 mg Ascorbic
c. 0.28 c. 6.7 acid to be given orally to Baby Cruz twice a
d. 0.65 170. A nasal inhaler contains 200 mg of d. 4.8 day. How many milliliters of Ascorbic acid
e.0. 34 propylhexedrine and 12.0 mg of menthol. How e. 7.2 drops containing 46 grains/ 15 mL container
many g of propylhexedrine would be used in should be used to provide for this dose?
166. If a dosage table for prefabricated drug preparing 200 inhalers?; 175. In what proportion should 10% and 2% a. 0.25 mL
product indicates the dose for a patient a.300 coal tar ointment be mixed to prepare 5% b. 0.40 mL
weighing 120 pounds to be 0.5 mg/kg of body b. 400 ointment? c. 0.35 mL
weight, taken three times a day for 10 days, c. 600 a. 3:5 d. 0. 45 mL
how many 20-mg tablets of the product d. 800 b. 4:5 e. 0.50 mL
should be dispensed? e. 500 c. 5:2
a. 41.25 d. 2:6 180. A physician ordered an iso-alcoholic elixir
b. 5.25 171. In what proportion should 95% alcohol e. 3:4 containing 40% alcohol, to be prepared from
c. 0.28 mixed with 30% alcohol to make 70 % low alcoholic elixir (10% alcohol) and high
d. 48.85 alcohol? 176. Using a vial containing 200,000 units of alcoholic elixir (78% alcohol). How many fluid
e. 39.65 a. 40 :25 penicillin G potassium , how many milliliters of ounces of low alcoholic elixir is needed to
b. 25: 40 solvent should be added to the dry powder in prepare 5 liters of iso-alcoholic extract.
167. If two pints of guaifenasin elixir is present c. 30: 45 preparing in a solution having a concentration a. 90.40
in the inventory, how many 4-fluid ounce d. 45:30 of 10,000 units per mL? b. 74.60
prescription can be filled? e. 15: 35 a.15 c. 94. 50
a. 6 b. 38 d. 78.70
b. 8 c. 20 e. 94.60
c. 10 d. 32
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

181. If the dose Diazepam is 150 ug , how e. 1125 mL a. 6258

many doses are contained in 0.120 g? 192. The cost of 100 tablets of Maalox Plus is b. 6255
a. 500 doses 187. A topical cream contains 0.2% (w/w) of P360.00. What should be the selling price per c. 6250
b. 750 doses Nitrofurazone. How many grams of hundred tablets to yield a 40% gross profit on d. 6350
c. 900 doses Nitrofurazone are there in one pound of the the selling price? e. 6245
d. 800 doses cream? a.P 540.00
e, 850 doses a. 2.0 g b. P600.00 199. What is the the dose of a drug for a child
182. If 1000 mL of an IV fluid contains 2g of b. 0.91 g c. P720.00 who weighs 28 lbs. if the average adult dose
an added antibiotics, how many grains of the c. 0.82 g d. P480.00 is 100 mg?
antibiotic were administered to a patient who d. 0.2 g e. P500.00 a. 18.6 mg
received 1 pint of the fluid? e. 1.0 g b. 17.6 mg
a. 10.6 gr 193. A bottle of Aspirin tablets is sold for c. 18.8 mg
b. 11.6 gr 188. Hepatitis B virus vaccine inactivated is P230.00, thereby yielding a gross profit of d. 17.8 mg
c. 12.6 gr inactivated with 1:5000 (w/v) of formalin. 25% on the cost. What was the cost of the e. 18.2 mg
d. 14.6 gr Express this ratio strength in percentage bottle of Aspirin tablets?
e. 13. 6 gr strength. a. P150.00 200. What is the dose of drug for a 6-year old
a. 2.0% b. P196.00 child if the average adult dose is 100 mg?
183. How many gallons of 20% (v/v) would be b.0.2% c. P184.00 a. 1/2 g
equivalent to 30 proof gallons? c. 0.02% d. P172.00 b. 1/2 gr
a. 50 gallons d. 0.002% e. P190.00 c. 1/2 mg
b. 65 gallons e. 20.0 % d. 1/2 ug
c. 75 gallons 189. How many mL of a 1:5000 solution of 194. What should the percentage markup on e. 1 gr
d. 60 gallons phenol can be made from 125 mL of a 0.5% the cost of an item to be to yield a 22.75%
e. 70 gallons (w/v) solution? gross profit on the selling price? 201. If 325 pounds of a chemical cost PhP
a. 3125 mL a. 28.75% 525, what will be the cost 125 pounds?
184. If 15 g of sodium borate are dissolved in b. 5 mL b. 31.55 % a. PhP 202
100 mL of water, what is the percentage c. 80 mL c. 32. 25% b. PhP 300
strength (w/w) of the solution? d. 1050 mL d. 29.45% c. PhP 221
a. 1.5% e. 500 mL e. 28.60% d. PhP 312
b.15.0% e. PhP 225
c. 3.0% 190. A solution contains 500 mg of Amoxicillin 195. The list price of Diphenhydramine syrup
d. 13.0 % per 120 mL and has a dose of 10 drops .If the is P450.00, less 15% .What is the net cost of 202. A drug formula for 750 capsules contains
e. 1.3% dispensing dropper calibrates 20 drops/mL, the syrup? 5.75 grams diazepam. How many grams of
how many mg of Amoxicillin are contained in a. P382.50 diazepam should be used in preparing 475
185. If a syrup containing 65% (w/v) of sugar each dose? b. P377.25 capsules?
is evaporated to 85% of its volume, what a. 2.1 mg c. P365.00 a. 2.52
percent (w/v) of sugar will it contain? b. 2.2 mg d. P390. 00 b. 3.01
a. 90% c. 2.75 mg e. P 372.00 c. 3.75
b. 85% d. 2.0 mg d. 4.02
c. 80% e. 2.4 mg 196. If 2 fluidounces of glycerin weigh 1140 e. 3.64
d. 76% grains , what is its specific gravity?
e. 72% 191. If the cost of 100 tablets of Paracetamolis a. 1.252 203. If 100 tablets contain a total 25 grams of
P270.00 and the pharmacist applies a 33 1/3 b. 1.327 paracetamol, how many tablets can be formed
186. How many mL of a 1:400 (w/v) stock % mark up on cost, what would be the selling c. 1.227 from 126 grams of paracetamol?
solution should e used to make 5 liters of a price? d.1.229 a. 525
1:2000 (w/v) solution? a. P150.00 e. 1.427 b.603
a. 750 mL b. P196.00 c. 500
b. 800 mL c. P184.00 198. If 250 units of an antibiotic weigh 1 mg, d. 504
c. 1000 mL d. P172.00 how many units are in 25 mg? e. 595
d. 1250 mL e. P190.00
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

204. If 40 kilograms of Green Soap was milligrams of metaproterenol sulfate, How d. 8 mg

bought at PhP 2550, how much will 15 kg many milligrams of active ingredient would be 214. An inhalational aerosol contains 450 mg e. 12 mg
cost? administered in each inhalation? of metaproterenol sulphate which is sufficient
a. PhP 952.65 a. 0.825 for 600 inhalations. How many micrograms of 219. How many grams of dextrose are
b. PhP 925.56 b. 0.750 metaproterenol sulphate would be contained required to prepare 4,000 mL of a 5% w/v
c. PhP 926.65 c. 0.600 in each inhalation? solution?
d. PhP 956.25 d.0.625 a. 750 a. 2000g
e. PhP 965.25 e. 0.525 b. 75 b. 8 g
205. How many milligrams of c. 0.75 c. 200 g
brompheniramine maleate would be contained 210. How many minims would provide 20 d. 7.5 d.125 g
in a 120- milliliter bottle, if a cough preparation grains of ipecac if the available ipecac syrup e. 0.075 e. 20 g
contains 5 milligrams of the same ingredient in claims to contain 42 grains?
each 5 millimeter dose? a. 0.476 215. If an injectable solution contains 40 ug of 220. A medication order calls for 1000 mL of a
a. 12 b. 3.81 a drug substance in each mL, how many dextrose intravenous infusion to be
b. 120 c. 480.25 millilitres will be required to provide 0.25 mg of administered over a 12 hr. Period. Using an
c. 1.2 d.60.00 the substance? intravenous administration set that delivers 10
d. 60 e.228.57 a. 5 drops/mL, how many drops per minute should
e. 0.12 b. 4.5 be delivered to the patient?
211. A multivitamin preparation contains 1000 c. 6.25 a. 12
206. How much will the company pay for 3 units of Vitamin A per milliliter of solution. How d. 6 b.11
and a half gallons of certain liquid preparation many units of vitamin A would be e. 5.75 c. 15
if 25 gallons of it cost PhP 14, 575? administered to a patient given 3 drops of the d. 14
a. PhP 20,000.00 solution from a dropper calibrated to deliver 216. If a cough syrup contains 5 mg of e. 9
b. PhP 2,400.50 25 drops per millilitre of solution? brompheniramine maleate in each 10 mL, how
c. PhP 2004.50 a. 240 U many milliliters of the agent will be contained 221. The usual dose of chlorambucil is 150
d. PhP 2040. 50 b.120 U in a 250 mL container of the syrup? ug/kg of body weight per day. How many
e. PhP2450.00 c. 100 U a. 500 mL milligrams should be administered to a patient
d. 25 U b. 125 mL weighing 122 lbs.?
207. How many grams of coloring reagent A e.125 U c, 0.2 mL a. 10.5
will a pharmaceutical fir, purchase if it intends d. 250 mL b. 11.2
to make 150 gallons of syrup using the 212. How many units of penicillin will 0.75 e. 100 mL c. 6.25
formula that indicates that 75 gallons of syrup milliliters contain if it is from a prepared d. 7.74
contains 15 grams of coloring reagent A? solution containing 5 million units of penicillin 217. If a potassium elixir contains 45 mEq of e. 8.32
a.50 per 5 milliliters? potassium ion in each 15 mL of elixir, how
b.100 a. 125,000 U many milliliters will provide 30 mEq of 222. If a low-strength aspirin tablet contains
c.65 b. 200,000 U potassium ion? 81 mg of aspirin per tablet, how many tablets
d. 150 c. 1,000,000 U a. 10 mL may be prepared from 0.5 kg of aspirin?
e. 5 d. 750,000 U b. 15 mL a. 6272
e. 800,000 U c. 20 mL b. 6
208. If 50 tablets claims to contain 2.5 grams d. 30 mL c. 6172
of an active ingredient, how much will 725 213. A drug preparation contains the e. 90 mL d. 6000
tablets contain? equivalent of 0.5 milligram of fluoride ion in e. 65
a. 38.50 g each millilitre. How many milligrams of fluoride 218. If a syringe contains 15 mg of medication
b. 37.25 g ions would be provided by a dropper which in each 20 mL of solution, how many 223. How many fluid-ounce bottle may be
c. 36.00 g delivers 0.8 mL? milligrams of medication would be filled from 5 gallons of cough syrup?
d. 36.25 g a. 0.4 administered when 8 mL of solution are a. 310 bottles
e. 39.00 g b. 4 injected? b. 320 bottles
c. 40 a. 11 mg c. 315 bottles
209. A metered dose inhaler, which is d. 0.04 b. 10 mg. d. 225 bottles
sufficient for 200 inhalations contains 125 e. 0.004 c. 6 mg e. 300 bottles
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

chlorpheniramine maleate with an error not a. 0.04%

224. How many grams of a chemical will 229. The dimensions of nicotine transdermal greater than 4%. b. 0.40%
remain in a 2.0 oz bottle after 15 grams are patch system are 4.7 cm by 4.8 cm. Express a. Weigh ½ of dilution, or 50 mg, which c. 0.03%
removed? these dimensions in corresponding inches,. contains 25 mg of chlorpheniramine maleate d. 0.35%
a. 824 grams a. 1.85 in x 1.89 in b. Weigh ½ of dilution, or 100 mg, which e. 0.30%
b. 836 grams b. 1.84 in x 1.87 in contains 50 mg of chlorpheniramine maleate
c. 857 grams c. 1.84 in x 1.89 in c. Weigh ½ of dilution, or 50 mg, which 237. If an injection contains 0.5% w/v of
d. 875 grams d. 1. 84 in x 1.85 in contains 50 mg of chlorpheniramine maleate diltiazem HCl, calculate the number of
e. 860 grams e. 1.85 in x 1.87 in d. Weigh ½ of dilution, or 100 mg, which milligrams of the drug product in 25 mL of
contains 25 mg of chlorpheniramine maleate injection.
225. If a drug costs P 125.00 per ounce, what 230. A pharmacist attempted to weigh 120 mg e. Weigh ½ of dilution, or 150 mg, which a. 125.0 mg
is the cost of 120 grains? of codeine sulphate on a balance beam with a contains 50 mg of chlorpheniramine maleate b. 124.5 mg
a. PhP 34.50 sensitivity requirement of 6 mg. Calculate the c. 125.5 mg
b. PhP 34.00 maximum potential error in terms of 234. A prescription calls for 0.2 mL of clove d. 123.0 mg
c. PhP 34.75 percentage. oil. Using a 25-mL graduated vessel calibrated e. 124.0 mg
d. PhP 34.80 a. 4.5 % in units of 5.0 mL, how much would you obtain
e. PhP 34.30 b. 4.0 % the required amount of clove oil using the 238. How many grams of potassium
c. 5.2 % aliquot method and alcohol as diluents? permanganate should be used in
226. A formula of cough syrup contains 1/8 d. 2.5 % a. Weigh 1/5 of dilution, or 2 mL, which compounding the following prescription?
grains of codeine phosphate per teaspoonsul e. 5.0 % contains 0.2 mL of clove oil Rx Potassium permanganate 0.02%
(5 mL). How many grams of codeine b. Weigh 1/20 of dilution, or 2 mL, which Purified Water ad 250 mL
phosphate should be used in preparing 1 pint 231. Using a graduated cylinder, a pharmacist contains 0.2 mL of clove oil a. 0.04% w/v
of the cough syrup? measured 30 mL of a liquid. On subsequent c. Weigh 1/10 of dilution, or 4 mL, which b. 0.40% w/v
a. 0.0769 g examination, using a narrow-gauge burette, it contains 0.2 mL of clove oil c. 0.03% w/v
b. 0. 759 g was determined that the pharmacist had d. Weigh 1/10 of dilution, or 2 mL, which d. 0.35% w/v
c. 0. 769 g actually measured 32 mL. What was the contains 0.2 mL of clove oil e. 0.30% w/v
d. 7. 590 g percentage of error in the original e. Weigh 1/5 of dilution, or 2 mL, which
e. 0.0759 g measurement? contains 0.4 mL of clove oil 239. A pharmacist adds 10 mL of a 20% w/v
a.6.7% solution of potassium iodise to 500 mL of
227. A drug substance has been shown to be b. 7.0% 235. A pharmaceutical formula calls for 0.4 D5W for parenteral infusion. What is the
embryotoxic in rats at doses of 50 mg/kg/day. c, 5.2% mL of the surfactant polysorbate 80. Using percentage strength of potassium iodide in the
Express the dose on the basis of micrograms d. 6.5 % water as the diluent and a 25 mL graduated infusion solution.
per pound per day. e. 5.9% vessel calibrated in 1 mL units, how could you a. 0.49% w/v
a. 22727.27 ug/lb/day obtain the desired quantity of polysorbate 80 b. 0.40% w/v
b. 22772.27 ug/lb/day 232. A torsion prescription balance has a by the aliquot method using water as the c. 0.03% w/v
c. 21727.77 ug/lb/day sensitivity requirement of 6.5 mg. How would diluents? d. 0.39% w/v
d. 21722.77 ug/lb/day 15 mg of a drug be weighed with an accuracy a. Measure 1/10 of the dilution, or 4 mL, which e. 0.30% w/v
e. 22227.72 ug/lb/day of 5%, using aliquot method and lactose as contains 0.4 mL of polysorbate 80
the diluent? b. Measure 1/10 of the dilution, or 2 mL, which 240. Rx Allopurinol 200 ug tablets 12 tablets
228. Tetracycline has been shown to form a. 132 mg contains 0.5 mL of polysorbate 80 Lidocaine HCl 1g
calcium complex in bone-forming tissue in b. 131 mg c. Measure 1/5 of the dilution, or 2 mL, which Glycerine qs ad 100 mL
infants given oral tetracycline in doses of c. 130 mg contains 0.4 mL of polysorbate 80 Calculate the percent strength of allopurinol in
0.011g/lb of body weight every 6 hrs. Express d. 131.5 mg d. Measure 1/10 of the dilution, or 2 mL, which the prescription.
the dose in terms of milligram per kg of bosy e. 129 mg contains 0.4 mL of polysorbate 80 a. 0.0043% w/v
weight. e. Measure 1/10 of the dilution, or 5 mL, which b. 0.0024% w/v
a. 23.4 mg/kg 233. A prescription calls for 50 mg of contains 0.4 mL of polysorbate 80 c. 0.0365% w/v
b. 24.2 mg/kg chlorpheniramine maleate. Using a d. 0.0035% w/v
c. 24.3 mg/kg prescription balance with a sensitivity 236. The biotechnology-derived product e. 0.30% w/v
d. 243.0 mg/kg requirement of 4 mg, explain how you would Neupogen contains 300 ug of filgrastin in the
e. 242.0 mg/kg obtain the required amount of product.
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

241. How many liters of a 2% w/v iodine 246. Rx e. 435 mg while being treated with lomotil. How many
tincture can be made from 123 g of iodine? Misoprostol 200 ug tablets 12 tablets people did not show positive results?
a. 6.20 L Lidocaine HCl 1g 251. One kilogram is equivalent to: a. 150
b. 6.15 L Glycerin qs ad 100 mL a. 1000 mg b. 10
c. 6.25 L Calculate the percent strength of misoprostol b. 2.4 lb c. 5
d. 6.22 L in the prescription. c. 1000 g d. 15
e. 6.18 L a. 0.0024% d. 15.432 g
b. 24.0% 258. It is frequently used to measure or
242. A biotechnology-derived product contains c. 0.024% 252. Mr. Lao is to receive a 260 mcg of drug 4 evaluate alcohols of given quantities and
300 ug of filgrastim in each millilitre of d. 2.4% times a day for 14 days. How many 1/250 strengths:
injection. Calculate the concentration of e. 0.24% grain tablets must be dispensed? a. proof spirit
filgrastim in the product. a. 58 b. proof gallon
a.0.03% 247. How many liters of a 2% w/v iodine b. 66 c. wine gallon
b. 0.05% tincture can be made from 123 g of iodine? c. 46 d. proof strength
c. 3% a. 6.15 L d. 56
d. 3.5% b. 32.5 mL 259. A solution with a concentration of 1:400
e. 3.2% c. 3.25 L 253. 2332 is equivalent to : is the same as:
d. 61.5 L a. MCCCXXXII a. 0.25%
243. If an injection contains 0.5% w/v of e. 6.15 mL b. MMCCCXXXII b. 0.05%
diltiazem hydrochloride, calculate the number c. MCMCCXXXII c. 4%
of milligrams of the drug in 25 mL of injection. 248. Rx d. MMCCXXXII d. ½%
a. 125 g Gentamicin (40 mg/mL) injection 2mL
b. 12.5 mg Gentamicin(0.3%) ophth. Sol’n 5mL 254. The standard temperature for specific 260. What is the weight of 0.06L of oil whose
c. 125 mg Calculate the percent concentration of gravity determination based on USP density is 0.9624 g/mL?
d. 1.25 mg gentamicin in this fortified ophthalmic solution. requirement (except in alcohol) is: a. 5.770 g
e. 12.5 g a. 13.6% a. 20˚C b. 57.74 g
b. 22.4% b. 15.56˚C c. 6.0 g
244. How many grams of Potassium c. 1.36% c. 4˚C d. 0.557 g
permanganate should be used in d. 16.36% d. 25˚ C
compounding the following prescription? e. 0.136% 261.. Last November 13, 2004 , Dra. Nunez
Rx 255. A cough syrup is labeled as containing delivered triplets at Delgado Memorial
Potassium Permanganate 0.02% w/v 249. How many milliliters of liquefied phenol 20% alcohol by volume,. Which of the Hospital. The babies weighed 2 kg, and 3.01
Purified water ad 250 mL should be used in compounding the following following statement are true? kg. What was the sum weight of the triplets in
a. 0.005 g prescription? a. The proof strength of this product is 40 kilogram?
b. 0.05 g Rx Liquefied phenol 2.5% b. each 100 mL of syrup contains exactly 20 a. 7.11
c. 0.05 g Calamine lotion ad 240 mL mL alcohol USP b. 7110
d. 50.0g a. 5.4 mL c. each 100 mL of syrup contains exactly 40% c.2105
e. 5.0 g b. 6 mL alcohol, USP d.711
c. 5.4 L d. None of these
245. A pharmacist adds 10 mL of a 20% w/v d. 4.2 L 262. Prof. Julienn Constantino has been
solution of potassium iodide to 500 mL of e. 54 mL 256. The body surface area can be taking 0.6 g of aspirin daily. If he has taken a
D5W for parenteral infusion. What is the determined by using a chart called: total of 12,600 mg of aspirin, how many days
percentage strength of the potassium iodide in 250. How many milligrams of procaine a. nomogram has he been taking this medication?
the infusion solution? hydrochloride should be used in preparing 120 b. hologram a. 2 weeks
a.3.9% suppositories each weighing 2 g and c. nanogram b. 21 days
b. 39% containing ¼ % of procaine hydrochloride? d. monogram c. 12 days
c. 4.0% a. 600 mg d. 2 ½ weeks
d. 0.0039% b. 725 mg 257. Lomotil is a drug used to treat patients
e. 0.39% c. 500 mg suffering from diarrhea. In a certain study, 5%
d. 635 mg of 300 people showed no positive results
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

263. A child with a body surface area of 1.07 268. The potency of these compounds is a. ½ tablet
m2 is to be given 2.5 mg of Valium® for every expressed based on their activity, except: 275. 0.03 milligrans equals how many grams? b. 2 tablets
m2 of body surface. How many mg of Valium a. antibiotics a. 0.000003 g c. 5 tablets
should be administered? b. endocrine products b. 30 g d. 2 ½ tablets
a. 2675 c.electrolytes c. 0.00003 g
b. 2 d. biological d. 0.03 g 282. How many milligrams are there in 3/8
c. 4.04 grains?
d. 2.675 269. Willem receives daily medication doses 276. How much of a substance is needed to a. 24.38
of 0.5 mg at breakfast, 0.5 mg & 0.25 mg at prepare 1000 mL of a 1:10, 000 solution? b. 23
264. Cimetidine is a drug that can produce lunch, and 0.75 mg at dinner. How many a. 0.1 g c. 23.38
side effects such as dizziness and a rash. The grams does Willemm consume each day? b. 10 g d. 24
number of people who experience these side a. 2 c. 0.01 g
effects is about 1% of all thise who take the b. 0.002 d. 1 g 283. The part of the prescription which directs
drug. If 1500 people take cimetidine, how c. 1.75 the patient on what to do:
many persons are expected to experience the d. 0.000175 277. Mr. Estrada, a patient with glaucoma a. signa
side effects? asked your help in interpreting the signs in his b. subscription
a. 150 270. Triturations are dilutions of potent prescription “Timolol 0.25% 1 gtt, BID OU.” c. inscription
b. 15 medicinal substances with a concentration of: You will tell him to place 1 drop in: d. superscription
c. 1.5 a. 100% a. both eyes
d. 100 b. 1:100 b. left eye 284. A STAT order is considered:
c. 1:1 c. right eye a. follow- up orders
265. Dr. A. Cruz orders aminophylline d. 1:10 d. both ears b as required
suppositories, gr. Viiss stat and non rep. How c. emergency drug
much drug should each suppository contain? 271. Concentration expressed in ppm means: 278. The ratio 1: 5000 when expressed in d. emergency order
a. 7 grains a. parts per mole percentage strength is:
b. 7 ½ grains b. parts per milligram a. 0.0002% 285. The dispensing direction to the
c. 7 grams c.parts per million b. 2 % pharmacist is:
d. 7 ½ grams d. parts per millilitre c. 0.02% a. inscription
d. 0.2% b. subscription
266. Dra. J. Villapana orders 272. It is used in solving problems that involve c. superscription
Diphenhydramine 50 mg. How many capsules mixing solutions of different percentage 279. A patient is to receive 0.26 mg of a drug d. transcription
should be given if the dose on hand is 0.025 g preparations: 4 times a day for 14 days. Hoe many 1 /250
in each capsules? a. allegations grain tablets must be dispensed? 286. If mercury freezes at -40 centigrade,
a. do not dispense b. triturations a.58 What is its freezing point on Farenheit scale?
b. 1 ½ c. dilutions b. 66 a. 40
c. 1 d. allegations c. 46 b. -40
d. 2 d. 56 c. 4.4
273. Quanitity of trace impurities in chemical d. 44.4
267. A prescription calls for a dose of 3 tsp of samples is expressed in terms of 280. The quanitity or amount administered to
medicine to be administered qid, 15 minutes a. mg % or taken by the patient for the intended 287. A dose of 10 mg is prescribed for your
before meals and at bedtime. How many days b. parts per million medicinal effect: patient. You have the medication with a dose
will a 350 mL bottle of the medicine last? c. range a. dosage regimen strength of 4 mg/mL. How much medication
a. It will last for 6 days d. mg/mL b. dosage form should you give to your patient?
b. It will last for 6 days but there is not enough c. dosage range a. 0.00025
for 7 days 274. Concentrations of weak solutions are d. dose b. 2500
c. It will last for 5 days, but there is not enough usually expressed in terms of: c. 2.5 mL
for 6 days a. percentage strength 281. The pharmacist prepares a 200 mcg d. 25 mL
d. It will last for 7 days, but there is not b. units dose of the anti-hypertensive drug, Clonidine
enough for 8 days c. Mcg (Catapres®). If each tablet equals 0.1 mg, the
d. ratio strength pharmacist should give the patient:
 Philippine Association of Colleges of Pharmacy PINK Philippine Association of Colleges of Pharmacy PINK

PHARMACEUTICAL CALCULATIONS PHARMACEUTICAL CALCULATIONS

288. You are asked to give a dose of 200 mg. 294. Jillian is a 8 yr old and weighs 67.5 a. 0.5 tablet
The available capsules are labelled 40 mg. lbs. The prescribed dose of erythromycin b. 1 tablets
How many capsules should be dispensed? stearate is 20 mg/kg per dose QID. You c. 2 tablets
a. 5 caps have erythromycin stearate 200 mg/5 mL d. 3 tablets
b. 1 cap in stock. Calculate the number of
c. 8 caps teaspoons of erythromycin/ dose for 299. Arrange the ff decimal number in
d. 2 caps Jillian. descending order according to size (1) 3.33
a. 4 tsp/ dose (2) 3.0330 (3) 3.333 (4) 0.0033
289. The prescribed reference dose for b. ¾ tsp per dose a. 4,2,1,3
Cefaclor (Ceclor®) is 40 mg/kg. If your patient c. 3 tsp/ dose b. 4,1,2,3
weighs 11 kg, what dose should you give? d. 1 tsp per dose c. 1,3,4,2
a. 0.0436 g d. 1, 3,2,4
b. 2000g 295. JM, a 16- Yr old boy weighs 45 kg
c. 3.63 mg and is to receive an initial insulin dose for 300. An injection of 0.004 g of Valium® has
d. 440 mg hyperglycemia and ketonuria. The been prescribed for a patient suffering from
prescription reads “regular insulin 0.1 U/kg muscle spasm. An ampule of Valium®
290. A child weighs 36 lb. What is her weight SQ QID”. How many units of regular labelled 5 mg/mL is in hand. How many mL
in kilograms? insulin will JM receive in each dose? will be injected?
a. 16. 36 a. 9.8 U/dose a. 0.8 mL
b. 79.2 b. 18 U/dose b. 30 mL
c. 0.06 c. 45 U/dose c. 0,2 mL
d. 7.92 d. 4.5 U/dose d. 1.25 mL

291. Cefixime (Zinnat®) is prescribed for a 6.3 296. You have received the following
kg infant. The reference dose for Zinnat is 8 prescription: “DRUG X 150 mg PO BID”.
mg/kg. You have Cefixime 100 mg/ 5 mL. What does the prescription order mean?
Calculate the number of mL/dose for the a. Administer Drug X 150 mg by mouth
infant. twice a day
a. 5.6 b. Administer Drug X 150 mg by mouth
b. 2.54 every other day
c. 2.56 c. Administer Drug X 75 mg twice a day
d. 6.5 d. Administer Drug X twice a day for a total
150 mg in a 24 hr period
292. How much atropine do you give a patient
who weighs 144 kg if the order reads 0.3 mg 297. The Physician precscribes Diltiazem
for every 100 lbs? HCl 60 mg for Mr. Herras. You have 30 mg
a. 8.3 mg tablets in stock. How many tablets should
b. 83 mg he receive?
c. 0.75 mg a. 0.5 tab
d. 7.5 mg b. 1 tab
c. 1.5 tab
293. You are to give penicillin 450, 000 U. The d. 2 tabs
bottle of penicillin is labelled 300, 000 U/mL.
How many mL will you dispense? 298. Dr. Gonzales prescribes Augmentin®
a. 0.8 mL 0.875 g po q 12h for Ms Y. Kurdi. You have
b. 1.5 mL Augmentin® 875 mg in stock. How many
c. 0.4 mL tablets shoud you dispense?
d. 2.5 mL