Grade 12/ Test 1 DNA: Code of Life Marking Guidelines January 2025
CAPRICORN NORTH DISTRICT
GRADE 12
LIFE SCIENCES
TEST 1: DNA CODE OF LIFE
MARKING GUIDELINES
MARKS: 60
1|P age
Grade 12/ Test 1 DNA: Code of Life Marking Guidelines January 2025
SECTION A
QUESTION 1
1.1.
1.1.1. A ✓✓
1.1.2. C ✓✓
1.1.3. D✓✓ (3 x 2) (6)
1.2.
1.2.1 Gene ✓
1.2.2. DNA Profiling ✓
1.2.3. Transcription ✓
1.2.4. Ribose ✓ (4 x 1) (4)
1.3.
1.3.1. A only ✓✓
1.3.2. A only ✓✓
1.3.3. Both A and B ✓✓ (3 x 2) (6)
1.4.
1.4.1. Translation ✓
1.4.2. Peptide bond ✓
1.4.3. Ribosome ✓
1.4.4. Transfer RNA / tRNA ✓ (4 x 1) (4)
SECTION A: [20]
SECTION B
QUESTION 2
2.1.
2.1.1. D- Chromatid ✓ (1)
E- Centromere ✓ (1)
2.1.2. 23 pairs ✓ (1)
2.1.3. (a) E ✓ (1)
(b) C / B ✓ (1)
2.1.4. (a) Nucleus ✓
Mitochondrion ✓ (2)
(b) Double helix ✓ (1)
2|P age
Grade 12/ Test 1 DNA: Code of Life Marking Guidelines January 2025
(C) DNA replication ✓ (1)
[9]
2.2
2.2.1. RNA / mRNA ✓ (1)
2.2.2. – Uracil is present ✓ (1)
2.2.3. 2- Ribose Sugar ✓
3- Adenine✓ (2)
2.2.4. Nucleotide ✓ (1)
2.2.5. Transcription ✓ (1)
2.2.6. – The double helix DNA unwinds ✓
- the double-stranded DNA unzips ✓ / weak hydrogen bonds break
- to form two separate strands ✓
- one strand is used as a template ✓
- to form mRNA ✓
- using free RNA nucleotides from the nucleoplasm ✓
- the mRNA is complementary to the DNA ✓
- mRNA now has the coded message for protein synthesis ✓ (any 5) (5)
(11)
QUESTION 3
3.1.
3.1.1. B- Nitrogenous base ✓
C- Phosphate ✓ (2)
3.1.2. Nucleotide ✓ (1)
3.1.3.
Monomer of RNA Monomer of DNA
-contains ribose sugar -Contains deoxyribose sugar
-contains the nitrogenous base Uracil -contains the nitrogenous base Thymine
(Mark first ONE only) Table (3)
3.2.
3.2.1. 31% Guanine ✓ (1)
3.2.2. 19% Thymine ✓ (1)
3|P age
Grade 12/ Test 1 DNA: Code of Life Marking Guidelines January 2025
3.2.3. -31% of Cytosine and 31% of Guanine make a total of 62% of DNA ✓
- and the rest has to be Thymine and Adenine ✓
- with the rest being 38% ✓
- half of this (half of 38%) will be Thymine and the other half will be Adenine ✓
(any 3) (5)
3.3.
3.3.1. (a) GAC ✓ (1)
(b) ACU ✓ (1)
3.3.2. (Gene) mutation ✓ (1)
3.3.3. - CTC on the DNA changed to CAC ✓
- Codons (on the mRNA) changed ✓ / GAG changed to GUG
- Anticodons (on tRNA) changed ✓ / CUC replaced by CAC
- which resulted in a different amino acid ✓ /Val (4)
3.3.4. - The cells will not receive enough oxygen ✓
- resulting in reduced cellular respiration✓ / a person lacking energy
/becoming tired/ anaemia (2)
(9)
TOTAL SECTION B: 40
GRAND TOTAL: 60
4|P age