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91PFO

Mr. Anil Singh, a 41-year-old male, underwent various laboratory tests on April 9, 2024, which included liver function tests, glycosylated hemoglobin, kidney function tests, lipid profile, and thyroid function tests. The results indicated elevated total bilirubin, AST, and ALT levels, suggesting potential liver issues, while his HbA1c was within normal limits, indicating no diabetes. Additionally, his lipid profile showed high triglycerides and low HDL cholesterol, which may increase cardiovascular risk.
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0% found this document useful (0 votes)
52 views15 pages

91PFO

Mr. Anil Singh, a 41-year-old male, underwent various laboratory tests on April 9, 2024, which included liver function tests, glycosylated hemoglobin, kidney function tests, lipid profile, and thyroid function tests. The results indicated elevated total bilirubin, AST, and ALT levels, suggesting potential liver issues, while his HbA1c was within normal limits, indicating no diabetes. Additionally, his lipid profile showed high triglycerides and low HDL cholesterol, which may increase cardiovascular risk.
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 15

Name : Mr.

Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

BIOCHEMISTRY

LFT - LIVER FUNCTION TEST


Serum

Total Bilirubin 1.58 mg/dL Adult: 0.2-1.3


Diazo Method Neonate: 1.0-10.5
Comment Kindly correlate clinically.

Direct Bilirubin 0.5 mg/dL Neonate: 0.0-0.6


Calculated Adult: 0.0-0.3

Indirect Bilirubin 1.11 mg/dL Adult: 0.0-1.1


Spectrophotometry Neonate: 0.6-10.5

Aspartate Transaminase(AST/ 67 U/L 17-49


SGOT)
IFCC method

Alanine Transaminase(ALT/ 101 U/L < 50


SGPT)
IFCC method

Alkaline Phosphatase 77 U/L 38-126


IFCC method

Gamma-Glutamyl Transferase 40 U/L 15-73


(GGT)
Szasz method

Total Protein 7.78 g/dL 6.3-8.2


Cholesterol Oxidase

Albumin 4.40 g/dL 3.5-5.0


Bromo-Cresol Green

Page 1 / 15

Dr. Radhika Puri


MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

Globulin 3.38 g/dL 2.3-3.5


Calculated

A/G ratio 1.3 1.1-1.8


Calculated

SGOT/SGPT- RATIO 0.7 0.7-1.4


Calculated
Total bilirubin is invariably increased in jaundice. Causes of jaundice are prehepatic, resulting from various hemolytic diseases; hepatic, resulting
from hepatocellular injury or obstruction; and posthepatic, resulting from obstruction of the hepatic or common bile ducts.
Aspartate aminotransferase is present in high activity in heart, skeletal muscle, and liver. Increased serum AST activity commonly follows
myocardial infarction, pulmonary emboli, skeletal muscle trauma, alcoholic cirrhosis, viral hepatitis, and drug-induced hepatitis.
Alanine aminotransferase is present in high activity in liver, skeletal muscle, heart, and kidney. Serum ALT increases rapidly in liver cell necrosis,
hepatitis, hepatic cirrhosis, liver tumours, obstructive jaundice, Reye’s syndrome, extensive trauma to skeletal muscle, myositis, myocarditis, and
myocardial infarction.
Alkaline phosphatase is elevated in fever and increased bone metabolism, for example, in adolescents and during the healing of a fracture;
primary and secondary hyperparathyroidism; Paget’s disease of bone; carcinoma metastatic to bone; osteogenic sarcoma; and Hodgkin’s disease if
bones are invaded. Hepatobiliary diseases involving cholestasis, inflammation, or cirrhosis increased ALP activity; also increased in renal infarction
and failure and in the complications of pregnancy. Low ALP activity may occasionally be seen in hypothyroidism.
Serum GGT is a sensitive indicator of hepatobiliary disease and is useful in the diagnosis of obstructive jaundice and chronic alcoholic liver
disease, in the follow-up of chronic alcoholics undergoing treatment, and in the detection of hepatotoxicity. GGT is more responsive to biliary
obstruction than AST, ALT, or ALP.
Total serum protein levels can be used for evaluation of nutritional status. Causes of high total serum protein concentration include dehydration,
Waldenström’s macroglobulinemia, multiple myeloma, hyperglobulinemia, granulomatous diseases, and some tropical diseases. Causes of low
total serum protein concentration include pregnancy, excessive intravenous fluid administration, cirrhosis or other liver diseases, chronic
alcoholism, heart failure, nephrotic syndrome, glomerulonephritis, neoplasia, protein-losing enteropathies, malabsorption, and severe malnutrition.

Page 2 / 15

Dr. Radhika Puri


MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

Glycosylated Haemoglobin - (HbA1c)


Whole Blood

Glycosylated Haemoglobin 5.0 % Normal: < 5.7


(HbA1c) Pre-Diabetes: 5.7-6.4
HPLC Diabetes: >= 6.5

Mean Blood Glucose 97.00


Calculated

HbA1C is used to monitor fluctuations in blood glucose concentration in the past 8 to 12 week’s period.
The reference interval defined as per American Diabetes Association guidelines 2016:
a) Less than 5.7% : Non Diabetic
b) 5.7 to 6.4% : at increased risk of developing diabetes in the future
c) More than 6.5% : Diabetic
d) Therapeutic glycemic target:
i. Adults: less than 7%
ii. Children with Type 1 diabetes : less than 7 %
e) Pregnant diabetic patients : less than 6.5%

Note:
• Targets may be individualized based on: Age/life expectancy, Comorbid conditions, Diabetes duration , Hypoglycemia status,
Individual patient considerations
Reference: American Diabetes Association. Standards of medical care in diabetes—2021.
Mean Blood Glucose is average Blood glucose which directly correlates with A1C, reported in the same units as blood sugar levels
(mg/dl). Thus it reflects the average glucose concentration in the past 8 to 12 weeks period. This should not be compared with
Fasting or Post prandial or random blood sugar which measures glucose concentration at that point of time of testing.

Advance Kidney Function Test


Serum

Urea 19 mg/dL 19-42


Urease

Page 3 / 15

Dr. Radhika Puri


MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

Creatinine 1.1 mg/dL 0.66-1.25


Twopoint Rate - Creatinine
Aminohydrolase

Blood Urea Nitrogen (BUN) 8.9 mg/dL 9.0-20.0


Calculated

BUN Creatinine Ratio 8.09 0-24


Calculated

Uric Acid 7.0 mg/dL 3.5-8.5


Uricase

Calcium 9.2 mg/dL 8.4-10.2


Arsenazo Method

Phosphorus 3.5 mg/dL 2.5-4.5


Phosphomolybdate formation

eGFR 87 ml/min/1.73 sq Normal: >= 90


CKD EPI m Mild decrease: 60-89
Mild moderate decrease: 45-59
Moderate to severe decrease: 30
-44
Severe decrese: 15-29
Kidney failure: < 15
Error: Subreport could not be shown.
ELECTROLYTES
Direct ISE

Sodium 144 mmol/L 137-145

Potassium 4.3 mmol/L 3.5-5.5

Chloride 105 mmol/L 98-107

Error: Subreport could not be shown.

Page 4 / 15

Dr. Radhika Puri


MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

Lipid Profile with calculated LDL


Serum

Total Cholesterol 200 mg/dl < 200


CHOD-POD

Triglycerides 206 mg/dL < 150


GPO-POD

HDL Cholesterol 29 mg/dL > 50


Direct

Non-HDL Cholesterol 171 mg/dL < 130


Calculated

LDL Cholesterol 130 mg/dL < 100


Calculated

VLDL Cholesterol 41 mg/dL < 30


Calculated

Cholesterol / HDL Ratio 7 3.3-4.4


Calculated

LDL:HDL Ratio 4.5 0.5-3.0


Calculated

HDL/LDL RATIO 0.2 > 0.4


Calculated

Page 5 / 15

Dr. Radhika Puri


MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

REMARKS TOTAL CHOLESTEROL(mg/dL) TRIGLYCERIDE(mg/dL) LDL CHOLESTEROL(mg/dL)


Optimal <200 <150 <100
Above Optimal - - 100-129
Borderline 200-239 150-199 130-159
High >=240 200-499 160-189
Very High - >=500 >=190

Lipid profile is a group test consisting of various lipids. Lipid profiles are generally collected with overnight fasting. However, Recent guidelines have
recommended non fasting samples for lipid profile for assessment of cardiovascular risk. The details for the study can be checked at
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2733560

In certain instances measurements in the same patient can show physiological and analytical variations. In such cases three serial samples at an interval of 1
week each are recommended for Total cholesterol, TG, HDL and LDL.

Cholesterol levels are increased in primary hypercholesterolemia; secondary hyperlipoproteinemia, including nephrotic syndrome; primary biliary cirrhosis;
hypothyroidism; and in some cases, diabetes mellitus. Low cholesterol levels may be found in malnutrition, malabsorption, advanced malignancy, and
hyperthyroidism.

Triglyceride levels are used in the diagnosis and treatment of patients with diabetes mellitus, nephrosis, liver obstruction, other diseases involving lipid
metabolism, or various endocrine disorders.

High Density Lipoprotein (HDL) cholesterol levels is used to evaluate the risk of developing coronary heart disease (CHD). The risk of CHD increases with
lower HDL cholesterol concentrations.

LDL (low-density lipoprotein) cholesterol level, sometimes called “bad” cholesterol, makes up most of our body’s cholesterol. High levels of LDL cholesterol
raise your risk for heart disease and stroke.

Very-low-density lipoprotein (VLDL) cholesterol is produced in the liver and released into the bloodstream to supply body tissues with triglycerides. High
levels of VLDL cholesterol have

been associated with the development of plaque deposits on artery walls, which narrow the passage and restrict blood flow.

Page 6 / 15

Dr. Radhika Puri


MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

IMMUNOLOGY

Thyroid function test (TFT)


Serum,ECLIA

Total T3 1.20 ng/mL 0.97-1.69

Total T4 8.76 µg/dL 5.53-11.0

Thyroid Stimulating Hormone 1.758 µIU/mL 0.400-4.049


(TSH)

Page 7 / 15

Dr. Radhika Puri


MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

Thyroid Stimulating Hormone (TSH), also called Thyrotropin is a hormone secreted into the blood by the Pituitary gland (a gland present in the
brain)). It signals the thyroid gland to make and release the thyroid hormones (T3 & T4) into the blood.

High TSH level indicates that the thyroid gland is not making enough thyroid hormone (primary hypothyroidism).

Low TSH level usually indicates that the thyroid is producing too much thyroid hormone (hyperthyroidism).

Factors influencing TSH levels

Fasting: TSH level shows a significant decline after meal intake in comparison to fasting values. This may have clinical implications in the
diagnosis and management of hypothyroidism, especially Subclinical hypothyroidism.1

Circadian Rhythm: TSH levels follow a circadian variation, reaching peak levels between Morning 2 – 4 am and at a minimum between Evening 6-
10 pm. The variation is of the order of 50%. hence time of sample collection during a day can significantly influence on the measured serum TSH
concentrations.2

Other Factors: Genetics, Poisonous substances and radiation exposure, Inflammation of the thyroid gland, Deficiency or excess of iodine in the
diet, Pregnancy, Certain medications – antidepressants, cholesterol lowering drugs, chemotherapy drugs, steroids, Thyroid cancer.

References:

1. Indian Journal of Endocrinology and Metabolism 18(5):p 705-707, Sep–Oct 2014.)

2. efaidnbmnnnibpcajpcglclefindmkaj/http://www.pnei-it.com/1/upload/thyrotropin_secretion_patterns_i n_health_and_disease.pdf

In pregnant females the reference range of TSH differs. Please refer the table below for the same:-

PREGNANCY TSH REFERENCE RANGE(uIU/mL)


1st Trimester 0.100-2.500
2nd Trimester 0.200-3.00
3rd Trimester 0.300-3.00

Page 8 / 15

Dr. Radhika Puri


MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

HEMATOLOGY

Complete Blood Count with ESR


Whole Blood

RBC count 5.33 mill/mm3 4.5-5.5


DC Impedance method

Haemoglobin (Hb) 15.4 g/dL 13.0-17.0


Cyanide-free SLS method

Haematocrit(PCV) 47.4 % 40-50


DC Impedance method

Mean Corpuscular Volume 89.0 fL 83-101


(MCV)
Calculated

Mean Corpuscular 28.9 pg 27-32


Haemoglobin(MCH)
Calculated

Mean Corpuscular 32.5 g/dL 31.5-34.5


Haemoglobin Concentration
(MCHC)
Calculated

Red cell distribution width 12.3 % 11.6-14.0


(RDW)
Calculated

Mentzer Index 17 Beta Thalassemia trait: < 14


Calculated Iron deficiency anemia: >= 14

Sehgal index 1486.1 Iron deficiency anemia: >= 972


Calculated Beta Thalassemia trait: < 972

Page 9 / 15

Dr. Radhika Puri Dr. Aekta


MD Pathologist
MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

Total WBC count - TC 6390 cells/cu.mm 4000-10000


Flow Cytometry

Differential Leucocyte Count - DC


Flow Cytometry

Neutrophils 57.5 % 40-80

Lymphocytes 29.6 % 20-40

Monocytes 7.9 % 2-10

Eosinophils 4.3 % 1-6

Basophils 0.7 % 0-2

Absolute Neutrophil Count 3674 / cu.mm 2000-7000


Calculated

Absolute Lymphocyte Count 1891 /cu.mm 1000-3000


Calculated

Absolute Monocyte Count 505 /cu.mm 200-1000


Calculated

Absolute Eosinophil Count 275 /cu.mm 20-500


Calculated

Absolute Basophil Count 45 /cu.mm 0-100


Calculated

Neutrophil Lymphocyte Ratio 1.9 Ratio 1.0-3.0


(NLR)
Calculated

Page 10 / 15

Dr. Radhika Puri Dr. Aekta


MD Pathologist
MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

Platelet count 185 10^3/ul 150-450


DC Impedance method

Mean Platelet Volume 11.1 fL 7-13


Calculated

Platelet haematocrit 0.206 % 0.2-0.5


Calculated

Erythrocyte Sedimentation 15 mm/hr 0-10


Rate (ESR)
Quantitative Capillary Photometry

1. Reference Ranges are in accordance with Dacie & Lewis Practical Hematology International Edition (12th).
2. As per International Council for Standardization in Hematology's recommendations Differential Leucocyte counts are additionally reported in
Absolute numbers in each cell per unit volume of blood.

Page 11 / 15

Dr. Radhika Puri Dr. Aekta


MD Pathologist
MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

CLINICAL PATHOLOGY

Urine Complete Analysis


Stool/Urine

PHYSICAL EXAMINATION

Volume 30 ml

Colour Pale Yellow Pale Yellow


Manual

Appearance Clear Clear


Manual

CHEMICAL EXAMINATION

pH 5.0 5.0-8.0
Double indicator method

Specific gravity 1.015 1.001-1.035


Refractive Index

Protein Nil Nil


Protein error of pH indicator

Glucose Nil Nil


Enzyme method GOD POD

Ketone bodies Nil Nil


Dipstick

Bilirubin Nil Nil


Azo coupling method

Page 12 / 15

Dr. Radhika Puri Dr. Anushree


MD Pathology
MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

Blood Negative Negative


Peroxidase activity

Urobilinogen Normal Normal


Dipstick

Leucocyte Esterase Negative Negative


Granulocyte esterase method

Nitrites Negative Negative


Griess method

MICROSCOPY EXAMINATION

Pus cells 2-3 /hpf 0-5


Flow digital Imaging

Epithelial cells 0-1 /hpf Occasional


Fixed point immuno-rate

RBCs Nil /hpf 0-2


Flow digital Imaging

Uric acid Crystals Nil Nil


Flow digital Imaging

Phosphate Crystals Nil Nil


Flow digital Imaging

Calcium Oxalate Crystals Nil Nil


Flow digital Imaging

Granular Casts Nil Nil


Flow digital Imaging

Hyaline Casts Nil Nil


Flow digital Imaging

Page 13 / 15

Dr. Radhika Puri Dr. Anushree


MD Pathology
MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

Amorphous urates Nil Nil

Amorphous phosphates Nil Nil


Flow digital Imaging

Yeast Nil Nil


Flow digital Imaging

Bacteria Nil Nil


Flow digital Imaging

Parasites Nil Nil

Mucus Absent Absent


Flow digital Imaging

Page 14 / 15

Dr. Radhika Puri Dr. Anushree


MD Pathology
MBBS, MD (Pathologist)
Consultant Pathologist
Name : Mr. Anil Singh Age / Sex : 41 Year(s) / Male Collected On : 04/09/2024 10:29 AM

Patient ID : OHP1QAA8823691 Ref. Doctor : Received On : 04/09/2024 01:31 PM


Visit No. : GG17704501 Client : Even Reported On : 04/09/2024 02:54 PM

Test Results Units Biological Reference Interval

Urine examination:

Increased protein in urine is seen in dehydration, kidney disorders, heart failure and transplant rejection. 24 hour urine protein and
Protein/creatinine ratio in a random urine sample recommended if increased.
Glucosuria can be seen in kidney disorders, uncontrolled diabetes mellitus, hormonal disorders, and pregnancy. To be correlated
with plasma glucose levels.
Ketonuria is seen in physical exercise, starvation, severe vomiting, exposure to cold, uncontrolled diabetes (diabetic ketoacidosis)
Increased bilirubin levels should be followed up with Liver function tests and indicates conjugated hyperbilirubinemia.
Increased urobilinogen can be seen due to haemolysis, megaloblastic anaemia and haemorrhage in tissues. Urobilinogen is
absent or reduced in obstructive liver disease and antibiotic therapy.
RBCs in urine (Haematuria) can be seen in anticoagulant therapy, bleeding diathesis and traumatic catheterization history to be
looked into. Dysmorphic RBCs suggestive of glomerular pathology. Non glomerular diseases line calculus, infections, tumours,
after strenuous exercise and diseases of the prostate.
Increase in pus cells are elevated in cases of UTI, to be correlated with urine culture, if clinically indicated. Infection can be in
either the upper or lower urinary tract or with acute glomerulonephritis, tubule interstitial nephritis. Leucocyte esterase detects
esterase enzyme released from the granules of leucocytes.
Infected urine may contain considerable amounts of nitrite as a result of bacterial nitrate reductase activity, and detection of nitrite
in urine is routinely used in the diagnosis of bacterial cystitis. It is indicative of the requirement of Urine culture and sensitivity
testing for identification and treatment of UTI.
Hyaline casts are seen normally (not associated with disease states); seen after strenuous exercise and with non renal diseases,
such as dehydration.
Granular casts can be seen in acute glomerulonephritis and pyelonephritis.

-- End of Report --

Page 15 / 15

Dr. Radhika Puri Dr. Anushree


MD Pathology
MBBS, MD (Pathologist)
Consultant Pathologist

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