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Assignment D-1.
2: Hardy Weinberg (20 points)
1. (1 point) A population has only two alleles, R and r, for a particular gene. The allele frequency of R is 20%. What are the frequencies of RR, Rr, and rr in the population. Show all your work.
2. (1 point) A large population consists of 400 individual, of which
289 are homozygous dominant (MM), 102 are heterozygous (Mm) and 9 are homozygous recessive (mm). Determine the allele frequencies of M and m.
3. (3 points) Imagine that a particular trait in a population is
determined by two alleles A and a. In a population of 4000 individuals, the number of those of each genotype is AA=2240, Aa=1520 and aa=240. a. What are the genotype percentages for this generation? AA _____ Aa _____ aa ______ b. What are the frequencies of the two alleles? c. Using the frequencies you calculated in the previous question, and assuming that the requirements for the Hardy-Weinberg Equilibrium are met, indicate the genotype frequencies for the next generation: AA _____ Aa_____ aa_______
4. (3 points) A population is in Hardy-Weinberg Equilibrium for a
certain trait. a. If p = 0.7, what is q? b. What is the frequency of the heterozygotes in this population? c. What is the frequency of individuals with the dominant phenotype?
5. (4 points) If 36% of the population has a phenotype that shows
the dominant trait: a. What is the frequency of the dominant allele? b. What is the frequency of the recessive allele? c. What % of the population will have the recessive trait? d. What % of the population will be heterozygous?
6. (3 points) Cystic fibrosis is a recessive condition that affects
about 1 in 2500 people in the Caucasian population of Canada. Calculate the following: a. The population frequencies for the dominant C and recessive c alleles
Hope Christian School Biology 30
b. The percentage of the population that is a carrier of the recessive gene c. The number of people in your closest twenty that are likely to be carriers of the cystic fibrosis allele.
7. (5 points) Myotonic dystrophy is an autosomal recessive disorder
affecting 1 in 500 people in Quebec. a. What is the expected frequency for the dominant allele in the Quebec population? b. What is the expected frequency for the recessive allele in the Quebec population? c. What percent of the Quebec population would you expect to be homozygous for the normal (non-disease) allele? d. Myotonic dystrophy affects one in 7500 people in all of Canada. What would be the expected frequency of carriers of myotonic dystrophy in Canada? e. Assuming the population of Canada is 30 million people, what number of people in Canada would you expect to be carriers?