ANY ONE of the following could indicate anaphylaxis
• Difficult/noisy breathing • Wheeze or persistent cough • Swelling of tongue • Persistent dizziness or collapse • Swelling/tightness in throat • Pale and floppy (young children) • Difficulty talking/hoarse voice • Vomiting and/or abdominal pain - for insect stings/bites • Any acute onset: hypotension, bronchospasm or upper airway obstruction, OR illness with skin features + respiratory/cardiovascular or persistent severe GI symptoms
IMMEDIATE ACTION • Remove allergen if still present • Call for help • Lay patient flat - do not allow to stand
Give intramuscular ADRENALINE (EPINEPHRINE) without delay
Deep IM into outer mid-thigh Repeat 5 minutely as needed
• CPR if needed
When able Adrenaline (epinephrine) doses
• Monitor HR, BP, RR, SpO2 Age (years) Weight (kg) Adrenaline 1:1,000 • Give O2 <1 < 7.5 • Support airway 0.1 mL 1–2 10 • IV access - adults + hypotensive children 2–3 15 0.15 mL 4–6 20 0.2 mL If hypotensive 7–10 30 0.3 mL • Give IV sodium chloride 0.9% 10–12 40 0.4 mL 20 mL/kg RAPIDLY > 12–adult > 50 0.5 mL
Additional measures MO/NP may consider
• Adrenaline (epinephrine) infusion - on advice of emergency medicine/critical care specialist • If upper airway obstruction - nebulised adrenaline (epinephrine) ± intubation/cricothyrotomy • If persistent hypotension/shock - sodium chloride 0.9% (max. 50 mL/kg in first 30 minutes) • If persistent wheeze - bronchodilators, prednisolone or hydrocortisone