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Work Operatio n Descript ion, Frequenc y

Operatio n
Nwnber Center
dis-assem ble.
Clean support rings, wash away salt 6M
0110 SCC-AE
kleposits .
Remove and clean pistons if any 6M
0120 SCC-AE
scratche s found on piston replace the
piston with new one and replace the
plunger Seal if required .
Reassemb le pump head. 6M
0130 SCC-AE
Replace PTFE frit in purge valve and 3M
0140 SCC-AE
butlet ball valve frit for
1290
0150 SCC-AE Sonicate cartridg e of active inlet valvelM
, Outlet check Valve and for 1260
passive valve with Methano l for 10
minutes.
0160 SCC-AE Replace AIV cartridg e once in six Months6M
wherever applicab le.
0170 SCC-AE ~heck the Purge valve gold seal; replace3 M
·-· - ·- - - · the gold seal -if-----requ ired.
0180 SCC-AE Replace the SS capillar y tube connecte d lY
from purge outlet to the 6-port valve
once in a year.
0190 SCC-AE Disconne ct the tubing's at degasser 6M
module and reverse flush inlet and
outlet rinse with the water.
0200 SCC-AE Agilent 1100/120 0/1260/1 290 Autosamp ler.1M

0210 SCC-AE Sonicate the Ro t or seal, Stator face, lM

Stator head, Needle seat in methano l for
10 minutes.
0220 SCC-AE Replace Rotor seal if required . 6M
0230 SCC-AE Verify the conditio n of metering Seal. 3M

0240 sCC-AE Replace the metering seal once in 6 6M

months.

~ffective Date: 04.04.20 22

Prepared By Date Reviewed By Date Approved By Date

Jame DineshKu mar 30.03.20 22Srikan th 31.03.20 22Naray ana 04.04.20 22
Thirucha nur Narra. Swamy
Nagasam udr
'ask list group : 103012

'ORM-CFT O-CE-0004 (2. 0) Page No.: 2 of 4

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preven tive Mainte nance Task List

Header Detail s
Group :103012
Group Counte r :14
Task List Title :AGILENT HPLC SYSTEM PM TASK LIST
Plant :FTO Unit 2
Depart ment :SCC

Opera tion Detail s

Freque ncy
Opera tion Work Operat ion Descri ption
Number Center
0010 SCC-AE Agilen t HPLC System 1100/1 200/12 60/129 0 3M

Check instrum ent log book exclud e 6M

0020 SCC-AE
mainte nance on recent ly servic ed items.
. -·- - ..

Perform genera l inspec tion of all lM

0030 SCC-AE
module s and clean precip itation s.
0040 SCC-AE Check that all waste trays are proper ly lM
mounte d.
SCC-AE Check that there is no blocka ge of the 3M
0050
drain tubes, Replac e the column inlet
3.nd outlet peek tubing 's.
0060 SCC-AE theck for proper mounti ng and 3M
functi onalit y of leak sensor .
0070 SCC-AE !Agilen t 1100/ 12 0"0/126 0 / 1290 Isocra tic /lM
IBinary / Quater nary/P rep
0080 SCC-AE Sonica te solven t inlet filter s in a lM
sonica tor with methan ol for 5 minute s.

0090 SCC-AE Replac e Suctio n filter s once in a Year. lY

0100 SCC-AE ~ake pump head out of Instrum ent and 6M

~ffect ive Date: 04.04.2 022

Prepar ed By Date Review ed By Date Approv ed By Date
iJame DineshK umar 30.03.2 022 Srikan th 31.03.2 022 INaraya na 04.04. 2022
'l'hiruc hanur Narra ISwamy .
INagasa mudr
~ask list group : 103012

~oRM-C FTO-CE -0004 (2.0) Page No.: 1 of 4

 •··
Dr, Reddy's "'4;•

.---- ----- --,--Wor

-=--- -,~ ~:; ;~- - --ipt ion Frequ .enc~
Oper ation
Numb er
k
Cent er
Oper ation Desc r _ -----:--::--=-::7--:-::z:-~-~M
3M -- -7
~~~~ ---4s _:c~c ~~A~E=-----i:~..;:;-,-:e::c::n,1 -lhc
- - - - - - • - t assem bly rod with
l:.J? ans po r d ubr i cat e the rod,
0250 lint free tissu e an 1
if nccc cssar y. fing er Grip
0260 SCC-AE nheck the tran spor t assr y if 13M
~ap for dama ges and rep ace
nece ssary .
0270 ISCC-AE Agil ent 1100 /120 0/12 60/1 290 ALS 61-1
Ther most at.
0280 sec AE ~hec k the func tioni ng of Ther most at. 6M
0290 SCC-A E Agil ent 1100 /120 0/12 60/l 29 0
!VWJJ/DAD/MWD/RI/FLD.
0M
0300 SCC-A E Open the flow cell lens and clea n the
lens with wate r by usin g lint fr~e
GM
tissu e and Flus h the flow cell ~1th LC
grad e Wate r at 2ml/ min for 10 minu tes.
0310 SCC-AE 0
,~heck for visu al insp
. e~tio n of sour ce 6M
lens for any fogg iness .
0320 '
SGG-~AE ·
Purg e all the Chan nels at f 1-GW ---rate 5 lM
ml/m in and flush the syste m at flow rate
~.5 ml/m in with Magi c solu tion .
0330 SCC-AE
:heck the func tioni ng of MCGV, flow 6M
shou ld be give n to all the port s A, B, C
~nd D such that only the resp ectiv e
~alv e shou ld work when prov ided with
flow . If it is malf unct ionin g repl ace
0340 the New MCGV.
SCC-AE
~erfo rm lamp inte nsit y test thro ugh the 3M
softw are/c ontr ol modu le. For V\IIJD aver age
inte nsity coun ts shou ld be grea ter than
5000 coun ts and high est coun ts shou ld be
grea ter than 1000 0 coun ts. For MWD/DAD
~owe st Inte nsit y in rang e 221n m to 350nm .
is grea ter tha Inte nsit y In rang e 190n m
to 350nm is less than 4500 00. For 1260
Syste m Aver age inte nsit y coun ts shou ld
be grea ter than 1600 00co unts and high est

!ffec tju0, ,-,. '

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Operation Work Operation Description Frequency

Number Center
counts should be greater than 320000
counts. For 1290 system lamp Intensity
should be 1500 to 400000 Counts for
lowest intensity and 1500 to 850000
~aunts for highest Intensity in the
range of 190 to 350nm. Record the
!Results in Remarks.
0350 SCC-AE Is Lamp energy Meeting criteria? 3M
0360 SCC-AE Is lamp to be replaced? 3M
0370 SCC-AE If yes, is lamp replaced? 3M
0380 ~CC-AE ~fter replacing the lamp, is lamp hours 3M
reset to zero?
0390 SCC-AE Number of Lamp hours 3M
consumed hrs · (Criteria: Not
More than 2000 hrs.).
0400 SCC-AE !Replace the Lamp if number of burned 3M
nours is more than 2000
hours.
. . .... -·- 3-M..
0410 ISCC-AE ·-IR-es-et-..the Lamp Hours if Lamp was
treplaced .
0420 SCC-AE Check for the stable pressure signal lM
through the software, or the control
module.
0430 SCC-AE !Perform internal wavelength calibration 3M
bf detector two times through the
software/co ntrol module.
V

0440 SCC-AE Check the Baseline stability. 3M

0450 SCC-AE 2heck for the stable pressure signal lY
With 100% IPA trough the Software, or
control module by generating pressure at
400 bar.
0460 SCC-AE Ensure all connections for tightness and lM
no leaks from the system. _

• •

fective Date: 04.04.2022