Drug Name Classification Indication Side Effect Nursing Responsibility

Generic Name: Therapeutic:  To reduce  Thirst Before:

Mannitol Diuretics intracranial  Dizziness  Assess the patient's medical history,
pressure  Headaches allergies, and baseline vital signs.
Brand Name: Pharmacologic:  To reduce  Nausea  Check weight, renal function, fluid
Osmitrol Osmotic Diuretics swelling due to  Vomiting balance, and serum and urine
cerebral edema  Increased Urine sodium and potassium levels.
Desired Dose: Output  Perform a detailed neurological
75 mL assessment to establish a baseline
 Dry mouth
for comparison.
Action Contraindication Adverse Effect
Route  Assess the patient's hydration status
IV
Increases osmotic  Contraindicated CNS: Seizures, Dizziness, by checking for signs of
pressure of in patients Confusion, Headache,
dehydration or fluid overload.
glomerular hypersensitive Fever.
Frequency During:
filtrate, thus to drug.
Every 4 Hours  Monitor blood pressure, heart rate,
inhibiting tubular  Contraindicated CV: Edema, and respiratory rate regularly during
reabsorption of in patients with Thrombophlebitis, infusion.
water and anuria, severe Hypotension, HTN, HF,
 Reassess neurological status
electrolytes. Drug pulmonary Tachycardia, Angina
frequently to detect any changes or
elevates plasma congestion, Pectoris, Vascular
improvements.
osmolality and frank Overload.
 Monitor intake and output carefully
increases urine pulmonary to detect any signs of fluid
output. edema, active ENT: Blurred Vision,
imbalance.
intracranial Rhinitis
After:
bleeding  Tell patient that thirstiness or dry
(except during GI: Thirst, Mouth,
mouth may occur, emphasize
craniotomy), Nausea, Vomiting,
drinking only the amount of fluids
and severe Diarrhea.
ordered
hypovolemia  Assess urine output and fluid
GU: Urine Retention.
balance to evaluate the response to
mannitol therapy and ensure
METABOLIC: adequate hydration.
Dehydration, Fluid and  Instruct the patient to promptly
Electrolyte Imbalance. report adverse reactions and
discomfort at IV site
RESPIRATORY:  Assess the patient’s response to
Pulmonary Edema. treatment by comparing
neurological status before and after
SKIN: Local Pain, administration.
Urticaria,
Injection-Site Reaction
(Infection, Phlebitis,
Venous Thrombosis).

OTHER: Chills And

Thirst