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Methimazole

Richmonde Ray C. Rojo's drug profile summarizes information on methimazole (brand name Tapazole). It is an antithyroid drug used to treat mild, moderate, and severe hyperthyroidism. Key points include: - Indications and dosages depending on severity of hyperthyroidism ranging from 15 mg daily to 60 mg daily for 6-8 weeks. - Contraindications include breastfeeding, hypersensitivity, and other antithyroid drugs. - Common side effects are CNS effects, CV effects, loss of taste, hypothyroidism, and hematologic abnormalities. - Nursing considerations include monitoring thyroid function, CBC results, and signs

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0% found this document useful (0 votes)
35 views3 pages

Methimazole

Richmonde Ray C. Rojo's drug profile summarizes information on methimazole (brand name Tapazole). It is an antithyroid drug used to treat mild, moderate, and severe hyperthyroidism. Key points include: - Indications and dosages depending on severity of hyperthyroidism ranging from 15 mg daily to 60 mg daily for 6-8 weeks. - Contraindications include breastfeeding, hypersensitivity, and other antithyroid drugs. - Common side effects are CNS effects, CV effects, loss of taste, hypothyroidism, and hematologic abnormalities. - Nursing considerations include monitoring thyroid function, CBC results, and signs

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Ren
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Name: Rojo, Richmonde Ray C.

Date:11/10/2022
BS Nursing 2

DRUG PROFILE

Brand and Action Classificatio Indication and Contraindi Side Effect/ Nursing Patient
Generic n Dosage cation Adverse consideration teaching
Name reaction
Generic May depress Chemical Treatment: Breastfeedi CNS: Monitor thyroid Tell patient to
name: CNS, which leads class: To treat mild ng; Drowsiness, function test take drug exactly
to sedation headache, result during as prescribed.
Methimazole and reduced Thiomidazol hyperthyroidism: hypersensiti paresthesia,
methimazole
Brand skeletal muscle e derivative TABLETS vity to vertigo Advise patient to
therapy
name: spasms. Adults and methimazol CV: Edema take drug with
Methocarbamol adolescents. Initial: EENT: Loss of food or
Tapazole Therapeutic e, other Check CBC
also alters 15 mg daily for taste milk to avoid
perception of class: antithyroid ENDO: results to detect nausea.
6 to 8 wk or until
pain. Antithyroid drugs, or Hypothyroidism abnormalities
euthyroid level is
their GI: Diarrhea, caused by Inform patient
reached. indigestion, that urine may
Pregnancy components inhibition of
Maintenance: 5 to 30 nausea, vomiting turn green,
myelopoiesis
Category: mg daily as a single HEME: black, or brown
D dose or in divided Agranulocytosis, until
aplastic anemia, Watch out for methocarbamol is
doses b.i.d.
leukopenia, signs of discontinued.
Children. Initial: 0.4
thrombocytopeni hypothyroidism
mg/kg daily
a Advise patient to
Maintenance:
MS: Arthralgia, avoid hazardous
0.2 mg/kg myalgia activities
SKIN: Alopecia, until drug’s CNS
To treat moderate jaundice, effects are known.
hyperthyroidism: pruritus, rash,
skin Instruct patient to
TABLETS
discoloration, avoid alcohol and
Adults and urticaria other
adolescents. Initial: Other: Lupus- CNS depressants
30 to 40 mg/ like symptoms, during therapy.
day for 6 to 8 wk or lymphadenopath
until euthyroid level y
is reached.
Maintenance: 5 to 30
mg daily
Children. Initial: 0.4
mg/kg daily
Maintenance:
0.2 mg/kg

To treat severe
hyperthyroidism:
TABLETS
Adults and
adolescents. Initial:
60 mg daily for
6 to 8 wk or until
euthyroid level is
reached.
Maintenance: 5 to 30
mg daily as a single
dose or in divided
doses b.i.d.
Children. Initial: 0.4
mg/kg daily
Maintenance:
0.2 mg/kg daily

As adjunct to treat
thyrotoxicosis:
SUPPOSITORIES
Adults and
adolescents. 15 to 20
mg every
4 hr on first day
Children. 0.4 mg/kg
daily as a single dose
or in divided doses
b.i.d.

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