Multi-Platform Devices to

Incorporate Advanced
Laser Technology in ����
By Cindy J. Papp, Contributing Editor

In conjunction with aesthetic procedures be- to expand their portfolio and patient demo-
coming more mainstream has come a desire graphics. VYDENCE Medical is a medical
for preventive and regenerative aesthetic technology manufacturer offering three su-
therapies. In addition, patients are seeking per-platforms with built-in laser cavities, plus
more non-invasive treatments that address seven laser and light-based handpieces, en-
the entire face and result in a natural look, abling almost 100 aesthetic applications. The
driving many providers to offer combination devices include ETHEREA-MX, ZYE ALX® and
procedures that treat multiple concerns, often ZYE YAG®, which are complete IPL and laser
in one session. technologies offering a broad selection of
wavelengths and spot sizes.
According to Stephen Eubanks, MD, a
board-certified dermatologist at Advanced “VYDENCE is very pleased to bring our di-
Dermatology and Cosmetic Surgery (Winter verse and highly efficacious technology to the
Park, Fla.), most aesthetic practices today U.S. market,” stated Andre Tanaka, founder
need to offer a combination of neurotoxins, and chief executive officer (CEO) of VYDENCE
fillers and laser devices in order to have a ver- Medical. “With over 3,500 of our platforms be-
satile and effective aesthetic practice “It does ing used by top providers all over the world,
not make economic sense to have five lasers, we are certain that the ETHEREA-MX and ZYE® Stephen Eubanks, MD
Dermatologist
but now it is possible to obtain a top-of-the- platforms will be a major asset and advantage Advanced Dermatology
line multi-platform device. Ideally, an aesthetic for American aesthetic practices, regardless of and Cosmetic Surgery
practice would be able to expand by offering if they are well-established or just starting out. Winter Park, FL
intense pulsed light (IPL) and resurfacing with
devices that will allow them to do so with a “Our lasers offer multiple, truly unparalleled
minimal outlay of cost.” treatment options in single or multiple ses-
sion approaches, giving providers the ability
Safety, efficacy and economics are Dr. to treat a variety of conditions with a one-of-
Eubanks’ top business priorities, and he be- a-kind suite of plug-and-play handpiece op-
lieves the ETHEREA-MX® multi-platform laser tions with no calibration time in between,”
device from VYDENCE® Medical (Miami, Fla.) Mr. Tanaka continued. He also explained that Andre Tanaka
makes sense for today’s aesthetic practices. their proprietary applicators – the ProDeep® Founder and CEO
“This is a very competitive market, and adding Nd:YAP 1340 nm and revolutionary hand- VYDENCE Medical
Miami, FL
this type of device to an aesthetic practice can PICO ® – incorporate unique technology
help providers get a head start on their busi- that is priced right, without any consumable
ness or help existing practices keep up with costs which further maximizes return on
the competition,” he stated. “The ETHEREA- investment (ROI).
MX is a great start, and the handpieces are
very high-end applicators that compete with Joel Cohen, MD, director of AboutSkin
the more expensive laser devices. In my opin- Dermatology and DermSurgery (Denver, Colo.),
ion, this device makes economic sense.” mentioned that the device and handpiece op-
tions add value to his practice. “I am very ex- Joel Cohen, MD
Director
Often referred to as an aesthetic treatment cited to have this platform. The versatility is AboutSkin Dermatology
workhorse, a multi-platform device allows extraordinary. Integrating a pico with a diverse and DermSurgery
providers to offer a broad range of treatments array of other handpieces (CONTINUED ON PAGE 6) Denver, CO

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 3

 allows treatment of pigment and tattoos as well relying on evidence-based laser aesthetic
as vascular lesions and wrinkles as part of a treatments can add confidence to both the
comprehensive platform.” provider and patient.

According to Dr. Eubanks, the ETHEREA-MX Aging naturally comes with the decline of new
has a combination of devices, or handpieces, collagen formation, resulting in fine lines, wrin-
that provide a broader range of treatments kles, skin discoloration and more. Aesthetic laser
compared to other multi-platform devices treatments are effective as they channel target-
currently available. Some of his most popular ed energy to both deep and superficial layers
handpieces include the ProDeep, DualMode® to stimulate collagen production for skin tighten-
and ACROMA-QS®. ing and more. Today, laser treatments are widely
used in cosmetic dermatology and surgery for
Dr. Eubanks shared his insights about these facial resurfacing, rejuvenation and pigmenta-
handpieces. “ProDeep is an Nd:YAP, unique in tion. In addition, according to the American
offering a 1340 nm wavelength. This non-abla- Academy of Dermatology laser treatments for
tive fractional device is my most useful applica- acne and scarring may be effective when added
tor so far,” he shared. “It is providing remarkable to a patient’s current treatment plan.2
reports of off-label uses, too, as it appears to
treat active acne. In addition, some physicians Thanks to advanced technologies like
are beginning to look at this wavelength for hair ETHEREA-MX and ZYE, laser treatments have
restoration, as well. expanded well beyond hair and tattoo remov-
al. Aesthetic practices are now able to offer fa-
“The DualMode is a fractional Er:YAG handpiece, cial rejuvenation, anti-aging treatments, laser-
which is not uncommon except that this has two based facials and peels with a device that is
different modes for tissue ablation and coagula- more comfortable, efficient and cost-effective.
tion in the same pulse, similar to the most ad-
vanced CO2 lasers,” Dr. Eubanks continued. Techniques and Tips
ETHEREA-MX allows physicians to customize
“With both 1064 nm and 532 nm wavelengths, treatments for patients of all demographics
the dual-wavelength, Q-switched ACROMA- by combining different handpieces to ad-
QS is a super powerful handpiece that pro- dress various layers of skin concerns. “I al-
vides much higher output energy than other ways start with the IPL-Sq handpiece because
devices. I can utilize multiple spot sizes with you want to leave the surface untouched
more control over the intensity and in fewer before you start treating pigmentation,”
sessions, which is great for my patients. In ad- Dr. Eubanks advised. “I may follow that with
dition, the IPL-Sq® handpiece
(or SquarePulse IPL®) has multi-
ple filters similar to some of the
more popular, higher-end IPLs,”
Dr. Eubanks reported.
Michael Gold, MD
Cosmetic Dermatologist Evidence-Based Laser
Founder Aesthetics
Gold Skin Care Center The last decade has seen a
Nashville, TN
rise in cosmetic procedures,
with the global aesthetic laser
market expected to grow at a
compound annual growth rate
(CAGR) of 16.6% from 2022
to 2030, according to Grand
View Research.1 Many in the
industry attribute this trend to
Lisa Kellett, MD
Dermatologist
social media along with the rise
DLK on Avenue of online meetings. Regardless Before and after treatment with the ETHEREA-MX using IPL-Sq and ProDeep
Toronto, Ontario, Canada of the reason, it is clear that Photos courtesy of Lisa Kellett, MD

6 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

ProDeep for fine wrinkles or acne
scars, and maybe do a third treat-
ment with the DualMode for a mild
tightening effect.”

Michael Gold, MD, cosmetic derma-

tologist and founder of Gold Skin
Care Center in Nashville, Tenn., has
been providing IPL laser treatments
for 30 years and recently added
the ETHEREA-MX to his practice.
“ETHEREA-MX is a very well-built plat-
form. An advantage is that you can
perform many treatments with just one
device, which is a benefit for many
providers in this time of economic un-
certainty. Another advantage is that Before and after four treatments with ProDeep
Photos courtesy of Alexandre Filippo, MD
the power is in the handpiece,” he
said. “I think this will be a very exciting Dermatologist Lisa Kellett, MD, combines derma-
option for new practices getting into the laser tological medicine with the latest laser technolo-
space and will be a welcome addition to those gies at her practice, DLK on Avenue (Toronto,
who are already in the laser space and want Ontario, Canada). “We are currently using the
to expand their offerings, without necessarily ETHEREA-MX platform,” she began. “Our hand-
breaking their bank. It is cost effective with a pieces include the ProDeep, which is great for
great ROI.” global skin rejuvenation, including scarring, and
effective in improving skin texture. We use the
Dr. Gold uses the ETHEREA-MX IPL-Sq hand- DualMode, which uses a fractionated laser to
piece for pigment and vascular concerns help thicken tissue and reduce the visible lines
as well as skin rejuvenation, and it has per- of aging and expression, for forehead, eyes,
formed well. “The IPL-Sq is an important de- neck and chest treatments. It benefits our pa-
vice because I do IPL treatments all day long tients with little to no discomfort and minimal
for vascular lesions, rosacea and pigmentary downtime because of the coagulating feature.
concerns. We use it for melasma on occasion, We also use the IPL filters of 540 nm and 515 nm
and photofacial treatments year-round, so we to treat red and brown issues of the skin.”
often have more than one IPL going at the
same time. VYDENCE’s IPL-Sq is comparable Dr. Kellett prefers multiple modality devices as
to what I use and helps me accomplish my they allow treatment stacking and the ability to
treatment goals. target numerous issues including dark spots,
rosacea and skin laxity as well as textural is-
“The handPICO 1064 nm wavelength is a fas- sues such rhytids. “From a clinical perspective,
cinating device, and can be used for fine lines, this translates into the treatment of patients
to make wrinkles less apparent, rejuvenate whereby in just one treatment session we are
the skin, and treat superficial scarring,” Dr. able to treat a variety of concerns by combin-
Gold continued. ing multiple treatment modalities.

Dr. Gold also anticipates using the ProDeep as “One of our favorite combination treatments is
part of a combination treatment for hair. “In the for acne, Dr. Kellet began. “We use the 400 nm
aesthetic space, treating wrinkles and helping blue light filter to target active acne pustules
patients grow hair are important,” he stated. and then we follow that up with a 640 nm filter
“I helped bring some of the non-ablative frac- to treat the post-inflammatory hyperpigmenta-
tional skin resurfacing devices to the FDA, so tion as a result of the acne. This one device
I am very comfortable with the technology. In has multiple handpieces, so we can streamline
addition, we treat hair all the time and we are our treatment by using the ProDeep non-ab-
excited about, and anticipate, using this device lative handpiece to reduce the inflammation
as part of our hair restoration treatments. and individual lesions, and then the fractional

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 7

 patient may have some brown spots
from the sun, textural changes with
fine lines, and then possibly telangiec-
tasia from aging, as well as some old
scarring or deeper rhytids. All of these
issues can be associated with aging.
We can treat all of these issues in one
treatment session. One of our treat-
ment regimens is to begin with the
DualMode followed by the IPL hand-
piece. This is a better experience for
the patient because they only have
to show up for one treatment session
and we treat the multiple manifesta-
tions of aging in that session. It is con-
venient for the patient, it is time sav-
Before and after four treatments with ProDeep ing for the provider, and we are able
Photos courtesy of Alexandre Filippo, MD to provide patients with a more effica-
cious treatment.”
handpiece to treat scarring from previous
acne. So, in one treatment session we treat the Diversify Your Practice
manifestations of acne, the active pustules and Many physicians and providers today are di-
the post-inflammatory changes. versifying their practices by adding aesthetics,
while many who are already in the aesthetics
“DualMode is a common handpiece we use business are diversifying their services. Doing
for aging skin,” Dr. Kellett continued. “Aging so allows physicians to open their practices
skin is a great example because you do not to a wider patient base with low-risk, elec-
just age in one dimension. For example, a tive procedures that offer positive outcomes

THE VYDENCE HANDPIECE COLLECTION

Most of the VYDENCE handpieces can be used with ETHEREA-MX (110 V) and ZYE (220 V) and can be easily
changed mid-treatment. The technology lies in the handpiece while the device is the energy source, which al-
lows for easy repair or replacement should something go wrong. Sapphire contact cooling can be fitted with all
handpieces for greater patient safety and comfort.
• ProDeep® Unique 1340 nm non-ablative fractional Nd:YAP laser. According to VYDENCE, ProDeep offers the
deepest penetration range for a fractional non-ablative laser.
• IPL-Sq® Versatile IPL handpiece with multiple wavelengths delivered through high-end designed cutting-off
filters, making a wide range of treatments available in a single technology.
• ACROMA-QS® Powerful Nd:YAG Q-switched laser handpiece providing a 20 ns pulse width and up to 1500
mJ of output energy in two wavelengths: 1064 nm and 532 nm.
• handPICO® Proprietary fractional picosecond handpiece designed for the most exclusive laser platforms
available on the market.
• GoSmooth® Long-lasting, gold-standard non-ablative fractional 1540 nm Er:Glass laser for mild, soft treat-
ments of the skin.
• LongPulse® The powerful, multi-pulse 1064 nm Nd:YAG laser for deep vascular lesions of the legs and face.
Also provides smooth, mild laser skin toning for all skin types.
• intenseIR® Comprehensive light-based solution for skin tightening with treatment applications for both face
and body indications via different treatment modalities within a single handpiece.
• DualMode® Powerful CO2-like effect provided by a dual-pulsed Er:YAG 2940 nm fractional laser for skin re-
surfacing combining both ablative, ablative/coagulative and coagulative pulses in a single handpiece.

8 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

for most patients. VYDENCE has kept
providers and patients in mind when
they created their multi-platform de-
vices, with not only multiple handpiec-
es, but also additional attachments
that diversify the application of certain
handpieces.

“The advantage of a VYDENCE device

for a practice is that it offers quality in
terms of time investment and physical
space,” said Dr. Kellett. “You can use
one room to treat multiple concerns,
whereas if you had one device to treat
hyperpigmentation and one for resur-
facing, it is more likely you would be
using two separate rooms. But one Before and after four treatments with ProDeep
device that does all of the treatments Photos courtesy of Alexandre Filippo, MD

allows you to use one room without

moving the patient around. In addi-
tion, if your state allows it, you can
delegate the treatments to your medi-
cal staff, freeing you and other office
rooms for more treatments.”

Device Support
Dr. Gold offered advice for providers
who desire to add laser technology
to their practices. “If you are a new
provider, keep in mind that VYDENCE
is one of the leading manufacturers
of laser devices. They have made it
through the tough FDA criteria, which
ensures their efficacy and safety. I be-
lieve adding a VYDENCE laser device
will help aesthetic practices differenti- Before and after four treatments with ProDeep
Photos courtesy of Alexandre Filippo, MD
ate themselves from other practices in
their area,” he mentioned.

Providers who invest in laser technology References:

should be assured they will have access to 1. Aesthetic Lasers Market Size & Share Report, 2022-2030.
(n.d.). https://www.grandviewresearch.com/industry-
adequate training and device maintenance as analysis/aesthetic-lasers-market#:~:text=The%20global%20
well as ongoing support. “I feel the VYDENCE Aesthetic%20Laser%20market%20is%20expected%20to%20
technology allows us to provide effective treat- grow%20at,USD%203%2C825.3%20million%20by%202030.
ments of multiple skin concerns, while working 2. Handler, MZ, Bloom BS, et al. Energy-based devices
with a team that is passionate about the tech- in treatment of acne vulgaris. Dermatol Surg. 2016
May;42(5):573-85.
nology and their products,” Dr. Kellett empha-
sized. “During training our team was provided
with a great foundation, so we were able to
adapt and learn quickly and we are now able
to use multiple ETHEREA-MX handpieces in
combination with existing technologies, which
results in consistent and effective results. Their
passion is contagious, and their technology is
backed by science and results.”

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 9

Editorial Advisory Board Alberto Goldman, MD Eliot Battle, MD Mark B. Taylor, MD, FAAD
Plastic Surgeon Dermatologist President and CEO
Past President CEO and Co-Founder Gateway Aesthetic Institute and Laser Center
Brazilian Society of Laser (South) Cultura Dermatology & Laser Center Salt Lake City, UT, USA
Porto Alegre, RS, Brazil Washington, DC, USA Michael H. Gold, MD
Alexander Z. Rivkin, MD Francine Young, RN, MEP-C Gold Skin Care Ctr.
Facial Cosmetic Surgeon Francine Queen of Threads Tennessee Clinical Research Ctr.
Founder Newport Beach, CA, USA Clinical Assistant Professor
Westside Aesthetics Gordon Sasaki, MD Vanderbilt University School of Medicine
Los Angeles, CA, USA Clinical Professor Nashville, TN, USA
Angelo Cuzalina, MD, DDS Department of Plastic Surgery Miles Graivier, MD, FACS
Past President Loma Linda Medical University Center Plastic and Reconstructive Surgeon
American Academy of Cosmetic Surgery, 2011 Private Practice North Atlanta Plastic and Reconstructive Surgery
American Board of Cosmetic Surgery, 2013 Pasadena, CA Roswell, GA, USA
Tulsa, OK, USA Gregory Buford, MD, FACS Miriam Emily Piansay-Soriano, MD, FPDS
Anil Rajani, MD Board Certified Plastic Surgeon Founder and President
Board Certified Physician and Surgeon Beauty by Buford Philippine Academy of Dermatologic Surgery Foundation, Inc.
CEO Englewood, CO, USA Associate Professor and Chief of Dermatology
Rajani MD Gregory W. Chernoff, MD, FRCS Davao Medical School Foundation
Hood River, OR, USA Plastic Surgeon Consultant in Dermatology and Dermsurgery
Atchima Suwanchida, MD, MS Medical Director Davao Doctors Hospital
Dermatologist and Dermatologic Surgeon Chernoff Cosmetic Surgery Davao City, Philippines
Director, Medisci Biointegrative and Anti-Aging Center Indianapolis, IN and Santa Rosa, CA, USA Nantapat Supapannachart, MD
Instructor of Dermatologic Surgery Hsien-Li Peter Peng, MD Dermatologist
School of Anti-Aging and Regenerative Medicine Dermatologist Clinical Professor
Mae Fah Luang University Founder and Director Ramathibodi Hospital, Mahidol
Bangkok, Thailand P-Skin Professional Clinic University Medical School
Barry DiBernardo, MD, FACS Taiwan, Republic of China Clinical Staff
Plastic Surgeon Bumrungrad Hospital
Jason Emer, MD, FAAD
New Jersey Plastic Surgery Cosmetic Dermatologist Bangkok, Thailand
Montclair, NJ, USA Beverly Hills, CA, USA Paul G. Ruff, IV, MD, FACS
Brooke Nichol, RN, CANS Jennifer Levine, MD Double Board Certified Plastic Surgeon
Founder Facial Plastic Surgeon Medical Director
Saving Face New York City, NY, USA West End Plastic Surgery
Austin, TX, USA Washington, DC, USA
Joel L. Cohen, MD, FAAD, FACMS
Bruce Katz, MD Director, AboutSkin Dermatology and DermSurgery Peter Huang, MD
Clinical Professor of Dermatology Medical Director, AboutSkin Research Plastic and Cosmetic Surgeon
Mount Sinai School of Medicine Associate Clinical Professor of Dermatology Director
New York, NY, USA University of California, Irvine Rebecca Cosmetic Institute
Greenwood Village and Lone Tree, CO, USA Taipei, Taiwan
Chan Yeong Heo, MD, PhD
Chairman Joel Schlessinger, MD Red M. Alinsod, MD, FACOG, ACGE
Department of Plastic Surgery Board Certified Dermatologist Urogynecologist and Pelvic Reconstructive Surgeon
Seoul National University Budang Hospital Skin Specialists PC Laguna Beach, CA, USA
Gyeonggi, Korea Omaha, NE, USA Renato Saltz, MD
Chang-Hun Huh, MD, PhD Joely Kaufman, MD, FAAD Plastic Surgeon
Clinical Assistant Professor Skin Associates of South Florida Salt Lake City and Park City, UT, USA
Department of Dermatology Skin Research Institute Robert Troell, MD, FACS
Seoul National University Budang Hospital Volunteer Associate Professor of Dermatology Board Certified Facial Plastic and Cosmetic Surgeon
Gyeonggi, Korea University of Miami, Miller School of Medicine Laguna Beach, CA and Las Vegas, NV, USA
Christine Petti, MD, FACS Coral Gables, FL, USA Sabine Zenker, MD
Board Certified Plastic Surgeon Jorge A. Perez, MD, FACS Dermatologist
Spa Medical Day Spa Plastic and Reconstructive Surgeon Dermatology Surgery Clinic
Torrance, CA, USA Perez Plastic Surgery Munich, Germany
Craig L. Ziering, DO, FAOCD Ft. Lauderdale, FL, USA Sabrina Fabi, MD
CEO and Medical Director Joseph Niamtu, III, DMD Goldman Butterwick Fitzpatrick Groff & Fabi, Cosmetic
Ziering Medical Worldwide Cosmetic Facial Surgeon Laser Dermatology
West Hollywood, CA, USA Richmond, VA, USA Volunteer Assistant Clinical Professor
David J. Goldberg, MD Katie Allyne Martin, PA-C University of San Diego
Clinical Professor of Dermatology Vice President of Clinical Operations San Diego, CA, USA
Mount Sinai School of Medicine Holden Timeless Beauty Sanjay Grover, MD, FACS
New York, NY, USA San Diego, CA, USA Diplomate
David McDaniel, MD Kei Negishi, MD, PhD American Board of Plastic Surgery
Director, Laser & Cosmetic Center and Associate Professor and Chief of Aesthetic Dermatology Newport Beach, CA, USA
McDaniel Institute of Anti-Aging Research Institute of Geriatrics, Tokyo Women’s Sheila Barbarino, MD
Co-Director, Hampton University Skin of Color Research Institute Medical University Cosmetic Surgeon
Adjunct Professor, School of Sciences Hampton University Tokyo, Japan Barbarino Surgical Arts
Adjunct Assistant Professor, Biological Sciences Kevin Brenner, MD, FACS Austin, TX & Redondo Beach, CA, USA
Old Dominion University Board Certified Plastic and Reconstructive Surgeon Suneel Chilukuri, MD, FAAD, FACMS
Virginia Beach, VA, USA Beverly Hills, CA, USA Dermatologic and Cosmetic Surgeon
Deborah S. Sarnoff, MD, FAAD, FACP Kian Karimi, MD Director of Cosmetic Surgery
Clinical Professor of Dermatology Double Board Certified Facial Plastic Surgeon Refresh Dermatology
NYU Langone Medical Center Medical Director and Founder Houston, TX, USA
New York, NY, USA Rejuva Medical Aesthetics Tess Mauricio, MD, FAAD
Deepak Dugar, MD Los Angeles, CA, USA Founder
Board Certified Facial Plastic Surgeon Klaus Fritz, MD M Beauty Clinic by Dr. Tess
Scarless Nose Institute of Beverly Hills Director San Diego, Chula Vista and Beverly Hills, CA, USA
Beverly Hills, CA, USA Dermatology and Laser Centers Tina Alster, MD
Doris Day, MD, FAAD, MA Associate Professor Director
Board Certified Dermatologist President, German Academy of Dermatology Washington Institute of Dermatologic Laser Surgery
Director Past President, European Society of Laser Dermatology Clinical Professor of Dermatology
Day Dermatology and Aesthetics Landau, Germany Georgetown University
Clinical Associate Professor of Dermatology Koenraad De Boulle, MD Washington, DC, USA
NYU Langone Medical Center Director Wendy W. Lee, MD
New York, NY, USA Aalst Dermatology Group Oculofacial Plastic and Reconstructive Surgery,
E. Victor Ross, MD Aalst, Belgium Orbit and Oncology
Director Kwun Cheung Hau, MBChB, MRCP, FHKAM, FHKCP,DCH Bascom Palmer Eye Institute
Cosmetic and Laser Dermatology Unit Dermatology Specialist Associate Professor of Clinical Ophthalmology
Scripps Clinic Hong Kong SAR, China and Dermatology
San Diego, CA, USA Lori Robertson, MSN, FNP-C University of Miami Miller School of Medicine
Edward M. Zimmerman, MD Co-Founder Miami, FL, USA
Medical Director The Aesthetic Immersion Wendy E. Roberts, MD
Aesthetic Revolution Las Vegas Skin Perfect Medical Board Certified Cosmetic Dermatologist
Las Vegas, NV, USA Brea, CA, USA Rancho Mirage, CA, USA

10 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 DO YOUR
PATIENTS
SUFFER FROM
HORMONAL
ACNE?

800-984-8268
vivantskincare.com
 Synchronous Ultrasound Parallel
Beam Technology Gains New
Approval for Upper Arm Laxity
By Kevin A. Wilson, Contributing Editor

Whether it manifests from old age, rapid surgery, there are thousands that will readily
weight loss or some other cause, tissue lax- try a non-invasive treatment.”
ity is a top aesthetic concern. With the rise of
weight loss drugs like glucagon-like peptide 1 SUPERB technology features multiple synchro-
agonists (GLP-1)1, and the resultant media hype nous US transducers to deliver a fractional and
surrounding the tissue laxity issues that stem controlled thermal effect, targeting 1 mm to 2
from rapid fat loss, the call for non-invasive tis- mm (centered at 1.5 mm) into the dermis. It de-
sue laxity therapies is skyrocketing. livers high volumetric tissue coverage, raising
target tissue to scientifically-determined levels
“There is no question about increasing de- (60° C to 70° C) for a therapeutically relevant
mand, and there is a large void in this space,” length of time, using four to five second pulses.
said Roy Geronemus, MD, director of the Laser Effects are achievable in a single treatment last-
& Skin Surgery Center of New York (New York ing 30 to 45 minutes, with minimal downtime.
City, N.Y.). “The demand is increasing because
the number of people that have lost weight To maximize both safety and optimal energy
has increased dramatically with the GLP-1 delivery, Sofwave includes integrated epider-
drugs. Most current alternatives that provide mal cooling and real-time skin temperature
meaningful improvement are surgical, which feedback. Parallel US beams delivered from
leave unsightly scars in almost all patients. So, multiple synchronous transducers causes di-
many people refuse to consider those options, rectional thermal coagulation parallel to the sur-
especially in the upper arm.” face of the skin, with a large contact area. This
results in low incidence of tissue inhomogene-
Roy G. Geronemus, MD Sofwave™ from Sofwave Medical Ltd. (San ity and reproducible, controllable energy de-
Director Clemente, Calif.) is a novel non-invasive ultra- position for all skin types with rapid treatment
Laser & Skin Surgery sound (US)-based modality designed specifical- time. As stated in a 2024 study of Sofwave by
Center of New York
New York City, NY
ly for tissue contraction. It boasts a growing list of Michael Gold, MD and Julie Biron, BSc: “High-
FDA clearances including wrinkle improvement, intensity, high-frequency, non-focused, parallel
eyebrow lifting, lax submental and neck lifting, ultrasonic waves are generated by seven trans-
short-term improvement in the appearance of ducers which propagate into the dermis layer
cellulite, improvement in the appearance of to depths of 0.5 mm to 2 mm and create con-
acne scars, and most recently, improvement in trolled thermal injury zones at the mid-dermis
upper arm skin laxity.2 Sofwave’s synchronous while preserving and avoiding damage to the
ultrasound parallel beam (SUPERB™) technology epidermis and other skin layers.”3
features an innovative and patented approach
Eric F. Bernstein, MD
Founder to induce collagen denaturation, which in turn “Unlike previous US devices, which were as-
Main Line Center for Laser promotes new collagen, elastin and hyaluronic sociated with significant pain, Sofwave found
Surgery acid (HA) production without compromising the the sweet spot for thermal injury and depth for
Ardmore, PA epidermal barrier.

“For skin tightening, surgery obviously provides

the best results,” mentioned Eric Bernstein, MD,
founder of Main Line Center for Laser Surgery
(Ardmore, Pa.). “However, for every patient will-
ing to undergo the costs, risks and downtime,
there are thousands who would pursue a non-
Suzanne Kilmer, MD surgical option. And the kind of laxity examined
Founder in this study, especially in a challenging-to-treat
Laser & Skin Surgery
Center of Northern
region such as the upper arm, is very difficult Upper arms before and three months after treatment
California to treat and surgery in this area leaves signifi- with Sofwave
Sacramento, CA cant scars. So, for every person that chooses Photos courtesy of Suzanne Kilmer, MD

14 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

ideal tightening with minimal discom-
fort,” Dr. Geronemus explained. “On the
upper arm there is thin, sensitive skin so
this is paramount. With the areas where
you have more laxity, you are much
more likely to get a preferential outcome
hitting that sweet spot.” Patients can be
treated regardless of age or skin type.

Suzanne Kilmer, MD, founder of the

Laser & Skin Surgery Center of Northern Upper arms before and three months after treatment with Sofwave
California (Sacramento, Calif.), has three Photos courtesy of Amy Forman Taub, MD
devices in her practice and they are al-
ways in use. “Patients are always looking for a perceived discomfort during treatment ses-
no-downtime tightening device that works, and sions. Throughout the study, anticipated tissue
if you have that, they are willing to pay for it,” responses and safety aspects were recorded.
she said. “We have a large practice with at least
a few physicians and RNs working at any given “There are a variety of ways people describe
time doing different treatments, and Sofwave the condition, but the basic setup is that for
runs almost all day. It is a robust workhorse older women, upper arm skin laxity is a strong
platform with no moving parts, it is easy to learn concern, especially when they may be going
and use, and designed to be safe for delega- out with short sleeves or no sleeves,” Dr. Taub
tion to ancillary staff. Demand is high because shared. “That need has been there for quite
it is safe and effective non-invasive technology, some time, but whatever we had was very pain-
which any aesthetic practice can use.” ful and not very effective – hovering around
50% efficacy, at best. With the rise of GLP-1 we
An FDA trial2 that led to Sofwave’s clearance have a growing number of people who are ex-
for improvement of the appearance of upper periencing laxity resulting from rapid weight
arm laxity was recently completed by der- loss, expanding demand considerably. We did
matologists Amy Forman Taub, MD, founder two treatments a month apart, with follow-up at Amy Forman Taub, MD
of Advanced Dermatology and Skincare three months after the final treatment.” Dermatologist
Boutique (Lincolnshire, Ill.), Dr. Bernstein, Dr. Founder
Geronemus and Dr. Kilmer. According to the Results showed that 93% of treated arms exhib- Advanced Dermatology
abstract, the multicenter, prospective, self-con- ited improvement in the appearance of upper and Skincare Boutique
Lincolnshire, IL
trolled clinical study included subjects (n=46) arm skin laxity, as per the correct identification
presenting with upper arm laxity of both arms of the post-treatment photograph by at least
(totaling 92 treated areas). Of these, 45 com- two of the three blinded evaluators. The mean
pleted the two-session protocol (one month improvement level was 0.98±0.59 units, based
between visits); 44 completed follow-ups out on the skin crepiness/laxity grading scale, re-
to three months. Pre- and post-treatment im- flecting an improvement of 31% of the grading.
ages were randomized for evaluation by three Measurements of upper arms’ circumference
independent masked reviewers not affiliated and diameter at follow-up (three months) dem-
with the trial. Each was asked to rank the up- onstrated significant reduction. Circumference Jordan V. Wang, MD,
MBE, MBA
per inner arm skin using a five-point crepi- of upper arms was significantly improved (mean Medical Director
ness/laxity grading scale (0=absent, 1=mild, reduction -7.5±14.2 mm); diameter was signifi- Laser & Skin Surgery
2=moderate, 3=severe, 4=extreme). Objective cantly improved as well (-4.5±7.4 mm). In subjec- Center of Pennsylvania
measurement of circumference and diameter tive assessment, 72% of the subjects reported Medical Research Director
Laser & Skin Surgery
at the maximal skin laxity point were taken for improvement. No device related adverse events Center of New York
each subject at each visit. Subjects were also were noted. The most common anticipated tis- Devon, PA and
asked to rank both their improvement and their sue responses were erythema and edema, New York, NY

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 15

 which resolved spontaneously after treatment. a lot more pain and swelling, as well as tis-
Most of the subjects reported levels of pain as sue necrosis, by going too superficial. Built-in
‘none’ to ‘mild’ (mean of 3.6±1.5 on zero to ten computer algorithms control the heating with
subjective pain scale) during treatment and no real-time temperature feedback. This assures
post-treatment discomfort. Thus, the overall con- heating to, and maintaining, a set tempera-
clusion was that Sofwave SUPERB treatment ture because ‘too high’ will cause more pain,
was demonstrated to safely improve the ap- and ‘too low’ lowers the ceiling for outcomes.
pearance of lax skin of the upper arms. “Just to Also, older treatments were very technique
avoid confusion – this study was not performed intensive, meaning they were very hard to re-
specifically on patients after rapid weight loss produce. With all the technology incorporated
with GLP-1,” Dr. Taub added. “That would be a into Sofwave, it is very easy to reproduce and
potential avenue for further study. know what you will be getting.”

“On top of the efficacy data, what stands out is Another key part of the continuing Sofwave
the tolerability of Sofwave,” Dr. Taub continued. story, according to Dr. Taub, is the proven in-
“I was involved with research using an older crease in elastin associated with treatment,
technology for upper arms and the difference especially when considering the issue of laxity
is profound. You have to understand that what due to rapid weight loss. “This device is one of
patients want in a non-invasive treatment are the very few, if not only, tissue tightening de-
safety, results and convenience, but if it is hard vices on the market that have been shown to
to tolerate we will have compliance issues. improve elastin. That is critical because what
That means they will not come back, will not happens when your skin sags and does not
get the full result, will not be happy and will not snap back? When you are young you have a
be referring their friends.” lot of elastin, but as we age and elastin (as well
as elastin production) decreases, even if you
Jordan Wang, MD, medical director of Laser & increase collagen you do not restore youthful
Skin Surgery Center of Pennsylvania (Devon, elasticity. As a result, when my patients come
Pa.) and medical research director for Laser & to me and say, ‘Should I wait until I am finished
Skin Surgery Center of New York (New York, losing weight to seek treatment for laxity?’
N.Y.), has served as lead author of three pub- I suggest that no, come around the halfway
lished clinical trials4-6 leading to Sofwave clear- point so that we can start the process of mak-
ances. “Sofwave SUPERB energy causes the ing new collagen and elastin to keep pace
coagulation, or the heating, of the dermis, with the changes. The farther down the road
with the effect centered at 1.5 mm,” he ex- you go before we begin to address laxity, the
plained. “So, you are not going too deep and harder it will be to try to firm up the area, what-
you are not going too superficial. You can get ever the area is.”

Upper arms before and five months after treatment with Sofwave
Photos courtesy of Ava Shamban, MD

16 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 lot of engineering went into it.
Sofwave developed a proto-
col that enables you to deliver
energy into the dermis with a
reasonably large surface area
without a lot of discomfort.
That translates into compli-
ance. With older US devices,
the pain involved meant that
patients might not come back
for enough sessions, which
is a problem we do not have
with Sofwave. In my experi-
ence patient satisfaction is
very high with proper patient
Upper arms before and five months after treatment with Sofwave selection, which is important
Photos courtesy of Adam Rubinstein, MD for any therapy. But this is
more difficult to achieve with
Return on investment is also a major advan- non-invasive technologies, and we will cer-
tage with Sofwave, according to Dr. Kilmer, tainly need a device to meet the growing de-
for three specific reasons. “At the top, the ‘no mand we are seeing with the proliferating use
downtime’ factor is a huge selling point be- of GLP-1 for weight loss.”
cause if it is safe, effective and has no down-
time, patients will sign right up. Second, it is an “Bear in mind that this is not an anticipated
easy procedure to perform and integrate into need,” Dr. Wang explained. “We are already
your office. It is designed to be safe and easy seeing this leap in demand within aesthetic
to use. Third, in my opinion, is the high safety medicine. They are getting these weight loss
profile. We have not had a problem with it, and medications from a doctor or medspa, using
we are using these all day, every day. Sofwave them successfully, and looking to us for solu-
is always paying for itself. tions after the fact. This rapidly growing de-
mand is only going to increase.”
“What brings things full circle is when patients
see their before-and-after pictures,” Dr. Kilmer References:
added. “We are a clinical trial site, so we take 1. Sauer N, Reining F, Schulze Zur Wiesch C, Burkhardt T,
top quality pictures, and when patients see Aberle J. Off-label antiobesity treatment in patients without
them they say, ‘Oh my God, I had no idea,’ be- diabetes with GLP-1 agonists in clinical practice. Horm Metab
cause they either forget how they used to look Res 2015;47(8):560-564.
or they do not have a good view of the treated 2. Data on file, Sofwave Medical Ltd.
area. It is always good to manage expectations 3. Gold MH, Biron J. Efficacy and safety of high-intensity, high-
with any treatment, but good pictures will help frequency, non-focused ultrasound parallel beams for facial
you harness patient satisfaction.” skin laxity. J Cosmet Dermatol. 2024 Jan;23(1):117-123.
4. Wang JV, Ferzli G, Jeon H, Geronemus RG, Kauvar A.
Also of high importance, the Company has Efficacy and safety of high-intensity, high-frequency, parallel
ultrasound beams for fine lines and wrinkles. Dermatol Surg
earned a reputation for integrity and transpar-
2021 Dec 1;47(12):1585-1589.
ency through its commitment to strong sci-
5. Wang JV, Bajaj S, Geronemus RG, Kauvar A. High-intensity,
ence. Physicians are listening and benefiting. high-frequency, parallel ultrasound beams for submental
“It is exciting to be working with a company lifting. Dermatol Surg 2023 May 1;49(5):532-534.
that really cares about science and works with 6. Wang JV, Bajaj S, Kauvar A, Geronemus RG. Eyebrow lifting
you,” Dr. Bernstein said. “They have an incred- from high-intensity, high-frequency, parallel ultrasound
ibly seasoned team behind the device, and a beams. Dermatol Surg 2023 Jul 1;49(7):718-720.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 17

 Dual Plasma Device Adds
Advantages of Argon Plasma
By John Jesitus, Contributing Editor

Combining the power of nitrogen plasma with argon plasma vacuolar changes occur in the
the safety of argon plasma facilitates relatively epidermis and follicular epidermis without ex-
painless non-invasive procedures for a range cessive thermal damage to the upper dermis.
of indications – from acne, rosacea and melas- This thermal modification destroys the seba-
ma to facial resurfacing, atopic dermatitis and ceous glands,3 he continued.
post-inflammatory hyperpigmentation (PIH). A
new device, PlaDuo from SHEnB (Seoul, South “If the operator increases the level of nitrogen
Korea) combines argon and nitrogen plasma plasma gradually,” Dr. Cheon began, “change
sources to balance safety and efficacy. in thermal-damaged sebaceous glands in
the upper dermis is relatively reduced.”
“Using two plasmas is the greatest strength of Conversely, dramatic energy increases melt
PlaDuo,” said Gwahn Woo Cheon, MD, owner sebaceous glands but generate tissue car-
of Maylin Clinic in Pangyo, South Korea. “With bonization and scarring.
a single plasma, one cannot treat a variety of
lesions effectively.” This treatment is well-suited for people whose
jobs require wearing makeup, which can cause
Aesthetic physicians skin reactions, and for entertainers who need
use existing nitrogen no-downtime acne treatment. Other good
plasma devices mainly candidates include young acne patients who
for facial resurfacing. cannot tolerate painful procedures such as
Dr. Cheon said that extrusion and peeling, and patients in whom
when he treated a photoallergy or phototoxicity causes hypersen-
Korean patient with sitivity to intense pulsed light (IPL) and lasers,
one such device, us- Dr. Cheon added.
ing manufacturer-sug-
gested parameters, Changes in inflammatory acne lesions and ro-
resolving the result- sacea start appearing three days post-treat-
Before and after three treatment sessions with PlaDuo ment. “More obvious changes start appearing
with two-week intervals between sessions
ing PIH proved very
Photos courtesy of SHEnB challenging. after about a week,” Dr. Cheon mentioned.
Maximal results can appear after the third treat-
According to Dr. Cheon, “PlaDuo is the only ment. “I normally recommend five treatments,
device that solves skin troubles and regener- performed one to two weeks apart, so that
ates the skin with very little or no pain using patients can maintain treatment effects lon-
two types of plasma based on various chemi- ger than after three treatments,” he continued.
cal and optical principles of plasma,” Dr. Cheon Applying skin boosters such as growth factors,
mentioned. exosomes or polydeoxyribonucleotide before
treatment can achieve synergistic effects.
Both argon and nitrogen plasma can kill bac-
teria because the 309 nm light they generate Because most patients want pain-free treat-
maximizes production of hydroxide, which is a ment, Dr. Cheon shared that repeat visits signif-
reactive oxygen species. Because plasma ap- icantly increased since he began using PlaDuo.
plication produces more hydroxide in wet skin, Most patients are satisfied with the treatment
SHEnB recommends gently misting the treat- and recommend it to their friends and family.”
ment area with water before treatment.
References:
Even at low energy levels the device offers po-
1. Kim CK, Kim H, Kim HJ, Cho SB. Antibacterial and antican-
tent antibacterial and anti-candidal activity1 and didal effects of atmospheric-pressure, non-thermal, nitrogen-
effective tissue remodeling, Dr. Cheon report- and argon-plasma pulses. Dermatol Ther. 2022;35(2):e15222.
ed. “In addition, argon-driven plasma produces doi:10.1111/dth.15222
light at 700 nm, so it can brighten the face.” 2. Cho SB, Kim H, Kim H, Yoo KH. Argon plasma: a new
approach for the effective treatment of inflammatory
Key to a successful treatment is using low en- acne vulgaris and enlarged pores in Asian patients.
ergy levels such as 0.53 J to 0.65 J for argon Medical Lasers. 2018;7:97 101. https://doi.org/10.25289/
ML.2018.7.2.97
plasma and 0.5 J to 1 J for nitrogen. “For non-in-
Gwahn Woo Cheon, MD 3. Kim H, Kim HJ, Kim HK, Hong JY, Cho SB. Effects of
Owner
vasive acne treatment or selective plasma de- argon and nitrogen plasma pulses on the skin and skin
Maylin Clinic livery to sebaceous glands, the argon plasma appendages in an in vivo animal model. Skin Res Technol.
Pangyo, South Korea pulse is mainly used,”2 Dr. Cheon shared. With 2020;26(1):81-90. doi:10.1111/srt.12767

18 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 Accelerate Healing and
Minimize Downtime with
Biome-Boosted Microneedling
By Cindy J. Papp, Contributing Editor

As the aesthetics industry continues the trend “Xycrobe technology feeds the fibroblasts for
towards more integrative treatments for im- an improved healing response by delivering
proved skin quality and health, one company Bioessentials™ like proteins, polypeptides, fatty
continues to demonstrate their commitment acids and antioxidants to optimize skin health
to holistic skin rejuvenation. Crown Aesthetics and vitality. The combination study conducted
(Dallas, Texas), pioneers of new innovations, by Crown Laboratories showed significantly
is defining a new category of skin biome care faster healing.”
with their patented BIOJUVE™ paired with
SkinPen® for optimal skin remodeling, while ac- Leslie Fletcher, NP-BC (Torrance, Calif.) shared
celerating healing and minimizing downtime. that the living Xycrobe Technology within
BIOJUVE implants into the skin allowing it to
“Xycrobe™ Technology in BIOJUVE is an inno- work 24 hours a day. “Xycrobes engraft them-
vative approach to enhancing skin health and selves into the pores to protect and benefit
quality by leveraging the power of skin-native, the skin by offering positive gene expression
beneficial microbes,” explained board-certified into the cells. Xycrobes come in the bottle as
dermatologist Doris Day, MD (New York, N.Y.). dormant, dehydrated, encapsulated cells un-
“Using the power of a living bacteria derived til they are hydrated with the activating mist,”
from a unique strain of C. acnes defendens, Mrs. Fletcher explained. “Chronic inflammation
Xycrobes optimize the skin’s ecosystem to maxi- in the skin leads to premature aging, an in-
mize skin health both on and below the surface crease in redness, oil production and scarring,
of the skin. Introducing this living microbe to the manifesting themselves as wrinkles. Xycrobes
existing skin ecosystem helps curate the right lead to a smoother and less ruddy skin tone.”
strains of microbes for visible
improvements in clarity, tone
and discoloration.”

According to Dr. Day, com-

Doris Day, MD
bining SkinPen treatments
Dermatologist with the application of
New York, NY BIOJUVE pre and post treat- Before (left), after treatment with BIOJUVE (center), and after treatment with
ment optimizes the skin’s BIOJUVE paired with SkinPen (right)
healing process and im- Photos courtesy of Leslie Fletcher, NP-BC
proves the overall rejuve-
nating effects, which are confirmed with clinical Mrs. Fletcher added that Xycrobes thrive on
studies. “Crown Laboratories’ clinical study pub- sebum and are not annihilated by extraneous
lished in the Journal of Cosmetic and Aesthetics antimicrobials, allowing them to address a wide
Dermatology recently showed significant im- range of skin concerns, including the reduc-
Suneel Chilukuri, MD, provement in overall aesthetic appearance tion of the appearance of coarse wrinkles and
FAAD and downtime. This is after in-office SkinPen fine lines. “Benefits that occur with BIOJUVE
Director of Cosmetic Surgery microneedling treatments when patients used a include an improvement in the appearance of
Refresh Dermatology
Houston, TX BIOJUVE biome care leading up to and follow- texture and tone that is essentially coming from
ing their treatments,” Dr. Day reported. the patient’s own healthy biome,” she clarified.

Suneel Chilukuri, MD, director of cosmetic sur- Crown Laboratories’ latest clinical results con-
gery at Refresh Dermatology (Houston, Texas) firm the outcome of SkinPen and BIOJUVE, re-
has played a key role in advancing cosmetic inforcing the idea that a balanced skin biome
dermatology in order to help patients achieve allows for optimal skin remodeling. “Treatment
their skin goals. “The mechanical trauma of the with SkinPen, complemented with BIOJUVE,
SkinPen stimulates the proper inflammatory allows us to harness the power of the skin bi-
Leslie Fletcher, NP-BC
Aesthetic Practitioner response with fibroblastic activity to improve ome, resulting in more value for our patients,”
Torrance, CA collagen and elastin production,” he said. concluded Dr. Chilukuri.

20 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 Plasma Energy Proving Versatile
and Effective in Aesthetics
By Cindy J. Papp, Contributing Editor

Plasma energy is proving to be an effective The PLEXR Glass Lift treatment is a combination
aesthetic treatment for skin regeneration and cosmetic procedure using the PLEXR Shower
revitalization. Today, patients can expect to tip and the revolutionary Act-O-Feel® topical
see a wider range of plasma procedures to solution. W. Christopher Croley, MD, aesthetic
address a variety of skin concerns thanks to physician and co-founder of Skin & Tonic in
inventive devices and treatments. Pace, Fla., explained how it works. “The PLEXR
Shower is a non-ablative plasma treatment that
PLEXR® Plus by Med-Results (Beverly Hills, delivers plasma energy over a large spot size
Calif.) is leading the way with treatments that of 1 cm to 2 cm and spread across a triangu-
allow physicians to offer innovative nonsurgi- lar shaped tip. A patient’s entire face can be
cal cosmetic procedures to a more diverse treated in about 20 minutes with no need for
range of patient demographics. topical numbing,” he explained. “Plasma energy
creates microchannels for delivery of a combi-
According to Gamil Makar, MD, a geriatrician nation of onabotulinumtoxinA and Act-O-Feel,
in Clifton, N.J., certain skin conditions can be which is a specialized blend of hyaluronic acid
distressing for patients and are very common. (HA), amino acids and vitamin C formulated to
“Three of these conditions are skin tags, milia provide immediate plumping, hydration and
and xanthelasma, and while they are not usu- smoothing of fine lines. Patients will immediately
ally severe, they can cause discomfort, em- see tighter, firmer skin and the biostimulatory ef-
barrassment and self-consciousness for those fect of plasma energy will encourage produc-
who have them,” Dr. Makar reported. tion of collagen and elastin, giving patients long
lasting results, with maximal results apparent
To address his patients’ concerns, Dr. Makar seven to ten days after treatment.
believes the answer lies
in plasma technology
with PLEXR Plus. “As an “It allows me to offer safe and quick
aesthetic medicine pro-
fessional, I see many
nonsurgical and non-invasive treatments
clients every day with an for many indications. I am not worried
array of skin conditions,”
he began. “PLEXR allows about scarring, darker skin color,
me to offer safe and
quick nonsurgical and
hypopigmentation or keloids, and often
non-invasive treatments treat my clients in just one or two sessions.”
for many indications. I
am not worried about
Gamil Makar, MD scarring, darker skin color, hypopigmentation “In my opinion, PLEXR Shower results are su-
Aesthetic Physician or keloids, and often treat my clients in just perior to traditional microneedling techniques,”
Clifton, NJ one or two sessions.” Dr. Croley continued. “Many of my patients have
now had both procedures and often report that
PLEXR Plus strategically employs pulsed their skin had a better glow, appeared lifted and
power technology to convert atmospheric ni- had more improvement in fine lines and wrinkles
trogen into plasma. “A distinguishing feature after receiving the PLEXR Glass Lift treatment,
lies in the fact that the energy does not pen- compared to traditional microneedling with a
etrate the skin significantly, resulting in little similar topical skincare product applied.”
to no thermal damage,” Dr. Makar added. “To
W. Christopher Croley, MD remove these bothersome skin conditions, PLEXR Plus allows physicians to offer a wide
Aesthetic Physician the procedure is relatively painless with topi- range of treatments for an even wider patient
Co-Founder
Skin & Tonic cal numbing, and my patients recover soon demographic, delivering both immediate and
Pace, FL after treatment.” long-term results.

22 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 Standout 3D Imaging
Technology Propels Patient
Consultations and Profits
By Kevin A. Wilson, Contributing Editor

What doctors and other caregivers do is made consultations. “This technology takes high
easier and made possible by powerfull tech- resolution 3D digital face or body photo-
nology which is becoming almost ubiquitous. graphs and can analyze them, then instantly
Patients expect to see it; physicians and staff make them available to office staff for the con-
rely on it. When considering notable, observ- sult. Images can be used to highlight shape
able advancements, innovations in imaging are or volume, skin quality and tone, wrinkles
arguably chief among them. Various imaging and pores, oiliness, vascularity (red area),
and scanning technologies have transformed pigmentation and more. We can rotate them
virtually all specialties of care. 360 degrees. When we have before and after
pictures we can use a slider function for com-
The LifeViz® Infinity Pro Series from Quantificare, parison,” he explained.
Inc. U.S. (Suwanee, Ga.) puts your dedication to
harnessing powerful technology for patients Quantificare’s patient image database is
front and center. Its available for peer comparison based on age,
three-dimensional (3D) gender, skin type and more, Dr. Chernoff con-
imaging capabilities are tinued. “Graphs are generated with values
a gold standard within ranging from +10 to -10, where +10 measures
the aesthetic industry, the top 2.5% of the best patients, and -10 rep-
serving to deepen con- resents the lowest 2.5% of subjects. So, at a
sultation assessment baseline, the patient can see how they com-
and outcomes evalua- pare to a population of their peers.”
tion, as well as dramati-
cally impact the patient As the patient is educated, it gives the infor-
consultation. The variety mation more relevance and generates excite-
of high-resolution digital ment. As results manifest, patient education
imaging capabilities of- and confidence are confirmed. “This also pro-
fer multiple measures of vides validated measures and demonstrates
skin and contour chang- changes in measures, providing empirical
es that can be visual- proof for scientific studies. This is valuable for
ized to reveal informa- us as 25% of our practice is dedicated to re-
tion and comparisons search,” Dr. Chernoff added.
beyond what is possible
Quantificare’s patient image database measures patients’ with the naked eye. According to Dr. Chernoff, the effect of LifeViz®
skin quality for comparison against a population of their
peers based on age, gender, skin type and more. Values The outcome: informa- technology on return on investment reaches
range from +10 to -10. tive consultations that beyond the device itself. The numbers in his
Photo courtesy of Gregory Chernoff, MD boost patient engage- office prove it. “Higher patient conversion for
ment and confidence, treatments on the front end, high patient sat-
raise conversion rates and maximize patient isfaction on the back end, across the board,
satisfaction with their treatment and overall ex- when LifeViz® visualization is used,” he re-
perience. This groundbreaking technology not ported. “It not only pays for itself, LifeViz® helps
only enhances efficiency by automating wire- other treatments pay for themselves. Over the
less image transfer, but also employs artificial in- years hundreds of thousands of dollars per
telligence (AI) for seamless image analysis and year in higher treatment plan acceptance can
organization, ensuring time-saving integration be attributed to the visualization technology,
into practice workflow. education-based confidence, and better un-
derstanding of results. Our patients tell us this
Facial plastic and reconstructive surgeon technology helps them. A happy patient is the
Gregory Chernoff, MD Gregory Chernoff, MD (Santa Rosa, Calif.) re- best source of referrals, and they tend to refer
Facial Plastic and
Reconstructive Surgeon lies on LifeViz® technology for research as more people when they have been engaged
Santa Rosa, CA well as improved diagnostics and clarity in and see verifiable results.”

24 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

CONNECT TO YOUR PATIENTS
THROUGH MORE VISIBLE RESULTS
 The Six Pillars of
Skin Health and Luminosity
By Cindy J. Papp, Contributing Editor

Research has shown that up to 80% of facial a holistic and medical approach so it is impor-
aging may be caused by the sun. Based on tant for them to use products that are backed
these findings, evidence-based topicals that by clinical and genetic data. “Using at least one
address sun damage will play an ever-increas- product from each of RATIONALE’s six pillars of
ing role in aesthetic medicine. skin health represents optimized skin nutrition.”

For 32 years science-based skincare company,

RATIONALE, has been developing solar specif-
ic formulations that assist in preventing and re-
versing the harmful effects of sunlight, which in-
cludes ultraviolet (UV), visible light and infrared
radiation, as well as environmental damage.

Founded in Australia in 1992, RATIONALE de-

buted in the U.S. (Los Angeles, Calif.) in 2022. A
leader in this field, the Company has pioneered
a suite of fully customizable formulations that
address what the company calls the ‘six pil- Brown spots before and after two years of using the
lars of skin health’. The first being immunity (B Essential Six Collections
group vitamins), then antioxidants (vitamins A, Photos courtesy of RATIONALE
C, E), SPF (superfluid zinc oxide, melanin and
heat shock proteins), barrier repair (intercellu- According to Dr. Orlinsky, the Essential Six
lar lipids, ceramides), pH recalibration (hydroxy Collections are widely popular, but RATIONALE’s
acids) and deoxyribonucleic acid (DNA) repair revolutionary #3 Tinted Serum Broad Spectrum
(DNA repair enzymes and retinoids). SPF50+ is one of the most elegant sunscreens
on the market. “This is a unique complex that
The Skin Identical technology incorporates not only offers comprehensive protection from
clinically proven actives into delivery systems the sun, but also protects skin from environmen-
that are intuitively recognized and utilized by tal damage in general,” Dr. Orlinsky clarified. “It
human skin. A wide range of treatments and is not just a sunscreen. It is a primer, a calming
products allows providers to offer a precisely- agent, a foundation, a highlighter and a moistur-
personalized, in-clinic facial and home-use izer. It includes zinc oxide as the only sunscreen
regimen for every patient and gives patients a luminous finish that is much
like a highlighter.”
RATIONALE conducts extensive skin research
on every formulation and the interactions be- Dr. Simmons-O’Brien added that along with
tween actives designed to offer superior solar the SPF50+ serum, RATIONALE also has a
Eva Simmons-O’Brien, protection and repair, including new studies line of Beautiful Skin Superfluid SPF30, of-
MD, FAAD that identify which genes are up and down fered in six universal skin tints ranging from M1
Medical and Cosmetic
Dermatologist
regulated by their Essential Six protocols. (Melanotype 1), for fair skin through M6 for dark
Co-Owner skin. “I am a woman of color and have a very
Simmons-O’Brien & Orlinsky According to medical and cosmetic derma- diverse patient population,” she explained.
Towson, MD tologist Eva Simmons-O’Brien, MD, co-owner “Some patients use the SPF50+ alone, but
of Simmons-O’Brien & Orlinsky (Towson, Md.), many add the Beautiful Skin tints for an ad-
“Our patients purchase RATIONALE products ditional glow along with extra protection. The
for use at home and our aesthetician incorpo- results are so vibrant that our patients’ friends
rates the professional line into her Hydrafacials,” sometimes come into our office to purchase it.”
she stated. “I use RATIONALE products after all
of my treatments, including laser and micronee- Dr. Simmons-O’Brien and Dr. Orlinsky em-
dling, because they are soothing and rejuvenat- phasized that RATIONALE complements their
Diane Orlinsky, MD, FAAD ing and can be used on diverse skin types.” practice and reinforces their belief that scien-
Medical and Cosmetic tifically based skincare leads to healthier skin.
Dermatologist
Co-Owner
Diane Orlinsky, MD, medical and cosmetic der- “Our patients know that we only use what
Simmons-O’Brien & Orlinsky matologist, and co-owner of Simmons-O’Brien works, and we truly believe in these products”
Towson, MD & Orlinsky, explained that their practice takes concluded Dr. Orlinsky.

26 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

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im-aesthetics.com
 Innovations in Polydioxanone
Technology Lead to New
Skin Booster and Micro-Infuser
By Cindy J. Papp, Contributing Editor

Patients with a timeless desire for glowing skin less firm and dehydrated giving the appear-
are continually seeking methods to achieve ance of aging, but when the skin is hydrated
a more hydrated and healthier complexion. and collagen is boosted it has a bright, tight
While polydioxanone (PDO) threads might not and dewy appearance,” she noted. “We infuse
be initially thought of or traditionally associated the PDO AfterGlo into the superficial layers
with providing radiance to the skin, PDO does of the skin utilizing the Glowpin, which has 19
stimulate collagen production while increasing small needles that create micro perforations
oxygenation to the tissue. Used primarily in aes- in the skin to deliver the serum into the top
thetics to reposition soft tissue giving a lifting ef- layer. This combination of micro infusion with
fect, PDO had not been considered as a topical the micro injury response creates an amazing
solution to produce glowing skin until now. outcome in the skin’s appearance.

Ever the innovator, PDO Max® (Syracuse, N.Y.)

has taken PDO technology even further with
their novel skin booster, PDO AfterGlo™, a topical
serum made of powdered PDO in a suspension
of non-cross linked hyaluronic acid (HA). While
PDO is completely metabolized by the body, it
boasts a prolonged absorption duration during
which skin texture is improved and brighter.

“This topical serum contains the benefits of

PDO collagen stimulation and is the first of its
kind, providing patients an innovative and less
invasive way to achieve dewy, hydrated skin
that everybody wants today,” explained Lanna
Before and immediately after the first treatment in a series
Cheuck, DO, founder and chief executive of- of four PDO AfterGlo facials with neurotoxins added to
ficer of Dr. Lanna Aesthetics (New York, N.Y.). shrink pores and treat rosacea
Photos courtesy of Christina Delgado, FNP-BC
For quick and accurate infusion of PDO
AfterGlo, and other skin boosters, PDO Max “PDO AfterGlo facials have become one of our
offers Glowpin®, a multi-needle stimulator with top treatments within our bridal community,”
an airless pump. “Glowpin creates microchan- Ms. Delgado continued. “We host bridal parties
nels, which allow the PDO AfterGlo serum to and offer treatments that combine the PDO
Lanna Cheuck, DO, FACS
Founder and CEO penetrate deeper while also creating an in- AfterGlo with a toxin to prep the participants.
Dr. Lanna Aesthetics flammatory response that signals to your body It has become a huge hit, and our referral rate
New York, NY to make more collagen. We often use Glowpin has increased tremendously.”
and PDO AfterGlo as an option for patients
who want a natural skin glow and for patients “The idea of regenerative and natural is so in
who want tight, bright skin,” Dr. Cheuck added. right now,” shared Dr. Cheuck. “As a result, I
have found a new subset of patients interested
According to Christina Delgado, FNP-BC and in procedures like PDO AfterGlo because it is
co-owner of Dr. Lanna Aesthetics (New York, a non-invasive skincare option, and providers
N.Y.), their PDO AfterGlo facial with Glowpin do not need expensive equipment.” As pa-
Christina Delgado, has preventative and anti-aging benefits and tients become more aware of aesthetics and
FNP-BC improves skin texture, hydration, radiance and skin health, regenerative treatments appear to
Co-Owner
Dr. Lanna Aesthetics the appearance of fine lines. “When the skin be poised as the future, with PDO AfterGlo and
New York, NY barrier is compromised it appears quite fragile, Glowpin leading the way.

30 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 Marketing Core Aesthetic
Treatments on Social Media
By Cindy J. Papp, Contributing Editor

When it comes to marketing commoditized, concerns. “It also contains a toning mode that
core aesthetic dermatology treatments, aes- delivers ten micro-pulses in one pulse, which
thetic providers have differing perspectives on makes the treatment very comfortable for the
the use of social media. Christopher Tomassian, patient while still delivering great outcomes,”
MD, is a board-certified dermatologist special- Dr. Tomassian added.
izing in lasers and medical dermatology with
over 2.5 million followers on social media. As Social media is considered one of the most
the founder of The Dermatology Collective cost-effective marketing strategies available
(Glendora, Calif.), he utilizes the Lucent IPL, an to aesthetic providers. Through the proper
intense pulsed light (IPL) system exclusively dis- channels, physicians can educate future pa-
tributed by Powered by MRP (Park City, Utah), to tients and interact with them as they build re-
offer a range of essential aesthetic treatments. lationships and trust. It can be used to inform
patients of new treatments, offer insight about
current treatments, highlight results and pro-
vide a low-cost avenue for patient acquisition.

“We educate our audience about IPL technol-

ogy with real-life before and after images and
patient testimonials to demonstrate its effec-
tiveness across various skin types and condi-
tions,” reported Dr. Tomassian. “We showcase
common skin concerns treated with the Lucent
such as rosacea, dark spots and photo-aging.
I also like to explain to my patients my reason-
Before and after treatment with the Lucent IPL ing for moving away from my previous IPL; the
Photos courtesy of Powered by MRP Lucent has stronger power and enhanced re-
sults, which is important for patients that have
“The Lucent IPL is a core treatment that is offered previously had a bad result or no benefit with
at The Dermatology Collective,” Dr. Tomassian re- other IPL devices.”
ported. “It is very easy to market via social media
as it treats a broad range of skin issues, such as Dr. Tomassian also shared that he makes it a
photo-aging, vascular lesions, pigmentation dis- point to educate his audience on the limita-
orders and even active acne. It is suitable for a tions of IPL, particularly when it comes to dark-
wider range of skin types, including those tradi- er skin types, a detail that is often highlight-
tionally harder to treat with light-based therapies. ed in responsible social media discussions.
Compared to other IPL systems, patients that I “Addressing both the positives and negatives
have treated with the Lucent IPL have achieved of IPL creates trust with my audience and my
pronounced results with fewer sessions, thanks patients,” he added.
to its precision and power.”
Honesty and full disclosure of treatment pho-
As Dr. Tomassian explained, because Lucent tos shared on social media as well as patient
IPL can treat many skin types and a wide vari- education are important to build trust in aes-
ety of conditions, it is frequently discussed on thetic procedures and practices. With treat-
social media. This system distinguishes itself ments that effectively address a wide array
from other IPL devices due to technology that of skin concerns and patient demographics,
Christopher Tomassian, MD allows for highly customizable settings such the Lucent IPL is an ideal choice for aesthetic
Dermatologist as adjustable wavelengths, pulse mode, pulse providers to showcase successful outcomes,
Founder
The Dermatology Collective types and energy levels delivering treatments demonstrate versatility and educate today’s
Glendora, CA that can be tailored to specific skin types and sophisticated consumers.

32 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

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 Regenerative Medicine:
The Synergy Between Aesthetic
Pharmaceuticals and Technologies
By Cindy J. Papp, Contributing Editor

Innovative technologies have helped shift aes- Plastic surgeon Carlos Bautzer, MD incorpo-
thetics towards regenerative medicine, and rates Toskani technologies into his aesthetic
Toskani US® (Fort Lauderdale, Fla.) is making it practice in São Paulo, Brazil. “I use the prod-
easy for aesthetic practices to keep up with pa- ucts throughout my surgeries and apply them
tient demand. The Company offers a full range with the Exceed device. During pre-op, I use
of topicals along with their the A-OX 360 cocktail for enhancing the skin
newly acquired Exceed quality. During surgery I use CO2 with Lumicen,
mesotherapy device. and post-surgery I use the Toskani Revitalizing
Cocktail, which is especially made for scars and
“I have always treated my marks on the skin,” he stated. “I also use Exceed
patients in a very special- to apply hair complex poli revitalizing (HCPR) for
ized way,” said facial plas- effective mesotherapy for the hair.”
tic surgeon Luis Assis, MD
(Ipatinga, Brazil). Toskani® Shino Bay Aguilera, DO, a board-certified der-
came with the possibil- matologist in Fort Lauderdale, Fla., uses NCPR to
ity of creating even more enhance the effects of biocollagen stimulators.
individualized protocols. “By supplying the extracellular matrix with optimal
The Company’s new stars amounts of signaling peptides, cofactors, vitamins
Before and 15 days after one session with peptides, include non-crosslinked and HA, we support fibroblasts in thriving and
A-OX and non-crosslinked HA performing at their best,” Dr. Aguilera reported.
Photos courtesy of Luis Assis, MD hyaluronic acids (HA),
biomimetic peptides and
“Our recent publication in the Journal of
sodium deoxyribonucleic acid of salmon milt
Drugs in Dermatology, released in September
(DNA-Na). I mainly use Toskani’s whitening com-
2023, highlights the success of our synergis-
plex poli revitalizing (WCPR), a brightening com-
tic approach. The study, conducted by Elina
plex which is a super blend of liposomal active
Theodorakopoulou, MD in Greece, employed
ingredients with peptides that deliver ten times
a unique poly revitalizing solution not available
more than similar products. It can be used with
in the U.S. The findings revealed a remarkable
various technologies such as lasers and mi-
increase in dermal thickness – 45.89% at three
croneedling. I drip about 1 mL to 2 mL after the
weeks and 65.39% at six weeks.1 Excitingly, we
technology and massage for one minute to en-
Luis Assis, MD are now able to replicate this Bionutriblend
sure greater absorption and reservoir of actives.”
Facial Plastic Surgeon technique in the U.S. using NCPR.”
Ipatinga, Brazil
Toskani MED® is highly regarded for profession- Since the publication, many have adopted and
al-grade cosmetic products that were created embraced the innovative concept of skin prim-
primarily for clinical use. In addition to WCPR, ing for other biocollagen stimulators, such as
products include nutritive complex poli revitaliz- poly-l-lactic acid (professor Alessio Redaelli in
ing (NCPR), a peptide-based mesotherapy treat- Milan, Italy), achieving comparable results by
ment, and eye complex poli revitalizing (ECPR), transforming a depleted and compromised ex-
a peptide-based mesotherapy cocktail for the tracellular matrix. “This will not just be a pass-
eyes. Lumicen is Toskani’s highly polymerized ing trend; it is destined to become the new
Carlos Bautzer, MD
Plastic Surgeon
DNA-Na to treat wrinkles and dry, dull skin. gold standard,” Dr. Aguilera added. “This pro-
São Paulo, Brazil gressive approach to critical thinking deepens
“This line of regenerators that act by regulating our understanding of the aging process at a
the senescence phenotype (on fibroblasts, im- cellular level, unlocking the potential for novel
munological cells and keratinocytes) are abso- ways to reverse the aging process.”
lutely necessary in my daily practice,” Dr. Assis
continued. “The DNA sodium salt found in the References:
Lumicen line is derived from salmon gametes 1. Theodorakopoulou, E., McCarthy, A., Perico, V., & Aguilera,
S. B. (2023). Optimizing Skin Regenerative Response to
and is pure. Using Lumicen as a drug deliv- Calcium Hydroxylapatite Microspheres Via Poly-Micronutrient
Shino Bay Aguilera, DO
ery after CO2 laser or any ablative procedure Priming. Journal of Drugs in Dermatology. https://doi.org/
https://jddonline.com/articles/optimizing-skin-regenerative-
Dermatologist ensures much faster tissue recovery and less response-to-calcium-hydroxylapatite-microspheres-via-poly-
Fort Lauderdale, FL downtime for the patient.” micronutrient-priming-S1545961623P0925X

36 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

AdobeStock.com/Beboy

38 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

Aesthetic Trends
and Treatments
from a Global
Perspective
By Cindy J. Papp, Contributing Editor

An increased global demand for aesthetic treatments in

recent years has led to the development of exciting tech-
nologies and innovative treatments. Driving this demand
are several factors including social media influencers, the
continuation of the ‘Zoom effect’, and advances in technol-
ogy, paving the way for 2024 to be another exciting year
in aesthetics.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 39

 “As co-founder and co-host of the Inside fat reduction techniques underscores a grow-
Aesthetic podcast, I am continually researching ing demand in India for cosmetic improvements
the latest trends and products,” reported cos- as well as enhanced skin health. “Novel formu-
metic doctor and facial aesthetic injector, Jake lations with polynucleotides, antioxidants and
Sloane, MD (Sydney, Australia). “One of the big- peptides is ushering in a new realm to skin re-
gest trends in Australia that we saw in 2023 juvenation through injectables,” she reported.
was a large drop in the number of volumizing “Advancements in injection techniques and
hyaluronic acid (HA) fillers being used, due to technology are being used to enhance the
an increase in the variety of newer injectables precision of filler placement, including the use
and a maturation of aesthetic trends.” of microcannulas, advanced imaging technolo-
gies and combination treatments to achieve
Dr. Sloane anticipates a newer class of in- more natural-looking results. Digital and ar-
jectables known as polynucleotides (PNs) tificial intelligence (AI) integration will further
to stand out in upcoming year. “Rejuran ® customize treatment planning tailored to indi-
(PharmaResearch Products Co. Ltd) is the only vidual anatomical needs and enhance patient
product to be approved here so far,” he report- experiences.”
ed. “In line with this trend of moving away from
high volumes of structural HA fillers, we should While the new year will see many updates
see more products that improve skin quality. It and changes, Steven Dayan, MD, facial plas-
is speculated that Allergan’s new hybrid filler tic surgeon and founder of DeNova Research
HArmonyCa™ may launch in Australia in late (Chicago, Ill.), believes that skin health, rejuve-
2024. The combination of HA and calcium hy- nation and patient education will drive the aes-
droxyapatite delivers immediate volumization thetic landscape in 2024. “In my opinion, up-
and longer-term biostimulatory results. Other dates will be based on what we already have,
biostimulatory products that may become avail- but we will evaluate patients differently as we
able include Gouri (DEXLEVO); a novel liquid start to create scales to measure improvement
polycaprolactone (PCL) and Aesthefill (Regen in skin quality.” He added that with social media
Biotech); a powder-made polylactic acid (PLA) and AI coming together, physicians and provid-
product that will rival Sculptra (Galderma, Fort ers should also be more judicious and consul-
Worth, Texas).” tative to properly manage patient expectations.

In addition, the continued rise in demand Regenerative Aesthetics

Jake Sloane, MD
Aesthetic Physician
for treatments like the Botox ® (Allergan Rungsima Wanitphakdeedecha, MD, a derma-
Sydney, Australia Aesthetics, an Abbvie Company) ‘lip flip’ and tologist in Bangkok Noi, Thailand, who spe-
‘baby botox’, along with fillers and biostimu- cializes in dermatologic laser and cosmetic
lators, may indicate a cultural shift that sees surgery, pointed out the rise of regenerative
injectables as alternatives to more
invasive procedures, paving the
way for continued innovations in
this field. Dr. Sloane added that
providers should keep their eye
Chytra Anand, MD on the newer class of botulinum
Cosmetic Dermatologist toxins such as prabotulinumtoxi-
Founder nA-xvfs, daxibotulinum toxin, and
Kosmoderma Skin Clinics Galderma’s relabotulinum toxin
Bengaluru, Karnataka
A. He anticipates that this further
competition and choice among the
existing toxin brands may lead to a
price war, making 2024 an interest-
ing time for injectors.

According to cosmetic dermatolo-

gist Chytra Anand, MD, founder of
Steven Dayan, MD Kosmoderma Skin Clinics (Bengaluru,
Facial Plastic Surgeon
Founder
Karnataka), the continued popular-
DeNova Research ity of minimally invasive treatments Before and after minimally invasive facelift and deep neck lift
Chicago, IL like fillers, peels and non-invasive Photos courtesy of P. Daniel Ward, MD, MS, FACS

40 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 arching trend that favors healthy,
radiant skin and notices a trend
in biostimulators for body con-
touring. “There appears to be a
notable shift away from the trend
for larger buttocks, paving the
way for a new approach in body
contouring. This shift in prefer-
ence might steer practitioners
towards utilizing more Sculptra
compared to traditional fat
transfer procedures,” shared Dr.
Kanaris. “Sculptra’s rising popu-
larity indicates a departure from
relying solely on fat transfers
for augmenting buttock size. Its
collagen-inducing properties of-
fer a compelling alternative, po-
Before and after jawline rejuvenation and rhinoplasty tentially reshaping the landscape
Photos courtesy of P. Daniel Ward, MD, MS, FACS of body sculpting by providing a
more controlled and versatile
aesthetics. “We are likely to witness a sus- option for enhancing contours and achieving
tained interest in platelet-rich plasma (PRP) desired buttock shapes.”
therapy with advancements in concentration
techniques and delivery methods,” she report- Dr. Dayan feels that regenerative technolo-
ed. “Stem cell treatments are expected to gain gies may be key in 2024 for certain patients
traction, especially in facial aesthetics and hair in the U.S. “I think the most pressing issue we
restoration, as advancements continue to un- will deal with in the upcoming year will be the
fold in this promising field. Providers may ex- “Ozempic” face, faces of people that are hav-
plore innovative combination therapies, syn- ing a significant amount of weight loss from
ergizing different regenerative agents such as Semaglutide, which is an extremely popular
Rungsima exosomes, stem cells and growth factors.” drug for weight loss. We are starting to see
Wanitphakdeedecha, MD
Dermatologist
the ramifications of it, and I think there will be
Bangkok Noi, Thailand In line with the regenerative aesthetics a significant drop in the number of fat reduc-
theme, thread lift technologies are continu- tion and sculpting treatments because of this
ally being updated and upgraded to reposi- new drug.”
tion skin and trigger collagen regeneration
for long-term results. “In the dynamic field of
thread lifts, providers can anticipate several Ozempic (by Novo Nordisk), generically
positive advancements in 2024,” reported Dr. known as Semaglutide 1 mg injection, was
Wanitphakdeedecha. “Notably, ongoing im- approved in the U.S. as a treatment for type
Nicole Kanaris, MD provements in thread materials are expected, 2 diabetes in 2017. The company also man-
Founder focusing on enhancing biocompatibility, lon- ufactures Wegovy, a Semaglutide 2.4 mg
Med Aesthetique gevity and overall effectiveness. The mini- injection, which was approved for weight
Johannesburg, South mally invasive nature of thread lifts, combined control in 2021. The company has since
Africa seen an increase in annual sales of both
with reduced downtime and quicker recovery
remain key selling points, offering patients a products of 58%.1
less intrusive alternative to traditional facelift
surgeries. Additionally, the trend of combining
thread lifts with other aesthetic procedures, “These patients may be losing some of the
such as dermal fillers or neurotoxins, is ex- reticular fat and it is possible those fat cones
pected to persist, allowing providers to tailor have a protective effect or benefit to the skin.
treatments for individualized and comprehen- Reticular fat is an extension of the subcutane-
P. Daniel Ward, MD, MS, sive facial rejuvenation.” ous fat and when lost, it has an impact on the
FACS
Medical Director and CEO
appearance of the skin. I think we are going to
Form Derm Spas Nicole Kanaris, MD, founder of Med Aesthetique have to do things to replace that,” Dr. Dayan
Salt Lake City, UT (Johannesburg, South Africa) sees an over- theorized.

42 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 “There is a lot of new science
and thinking that our fillers and
biostimulators are working by
stimulating the adipose stem
cells within those fat cones,” Dr.
Dayan continued. “Fillers and
biostimulators may be work-
ing on the stem cells within the
deeper dermis and the super-
ficial subcutaneous tissue, so I
think we are going to see that will
be an area for research and an Pigmentation before and two months after one treatment with the StarWalker
area of excitement.” PQX from Fotona
Photos courtesy of Mark Taylor, MD
Surgical Outlooks
P. Daniel Ward, MD, medical director and chief more of an endoscopic approach to my facelift
executive officer (CEO) at Form Derm Spas patients and have been very pleased with their
(Salt Lake City, Utah), feels that rather than degree of improvement and the minimization of
moving away from aesthetic surgical options, scarring,” Dr. Ward shared.
patients will be more discerning about which
nonsurgical options are used. “There has been Product and Technology Updates
a lot of discussion over the past year that in The StarWalker® PQX from Fotona (Farmers
some cases, nonsurgical treatments can lead Branch, Texas) is the newest addition to the
to problems and affect the results of future high-performance StarWalker laser family. It
procedures,” Dr. Ward pointed out. “For ex- delivers high pico power and energy with a
ample, if a patient is considering a rhinoplasty, selection of sophisticated state-of-the art ac-
they might refrain from doing a nonsurgical cessories to offer an exceptional combina-
treatment to their nose as it may alter the out- tion of speed and precision. Picosecond laser
come of surgery. Similarly, some nonsurgical technology is considered an effective tool for
treatments for the face may cause scarring un- skin pigment removal without damaging sur-
der the skin, which can complicate future pro- rounding tissue or causing unwanted side ef-
cedures like a facelift. fects. Additionally, picosecond laser pulses
induce skin remodeling in a photoacoustic,
“As far as surgeries, one of the biggest chang- completely non-thermal way, making it a safe
es that happened in 2023 was the growth option for all skin types. With just one device,
of the deep neck lift,” Dr. Ward continued. “I practitioners can offer a wide range of treat-
think the deep neck lift and jawline enhance- ment possibilities in one device, including
ment will continue to expand over the next few acne scar revision, pigmented lesions, wrinkle
years.” He added that in addition to the deep reduction and tattoo removal. The system’s
neck lift, other procedures like surgical
facial contouring where the buccal fat
is removed or transferred to another
area in the face will continue. “I also
think that chin augmentation and maybe
even jawline augmentation will increase.
People have learned that filler injec-
tions and nonsurgical treatments can
lead to some improvement, but surgery
offers a lot more bang for your buck.”

Regardless of a rise in demand for non-

invasive procedures with less downtime,
Dr. Ward believes the traditional facelift
will remain popular. “One of the biggest
changes going on in the facelift world is
the push towards more minimally inva-
Before and immediately after treatment with Glowpin by PDO Max
sive incisions. I certainly have adopted Photos courtesy of Alexis Robertson, LE

44 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 Bring brightness to the surface
Target dull complexion for radiant, more luminous skin with
NEW PCA SKIN® HydraBright and Bright & Even Peel.

Brightens and Improves skin radiance

hydrates dry, lackluster by 47% after just
skin in just 21 days.* one peeling session.

pcaskinpro.com | 877.PCA.SKIN (722.7546) | © 2024 CP Skin Health Group, Inc. | ♻ please recycle
* Based on a case study with 13 individuals over a 12 week period
** Based on a 4 week case study with 15 subjects
 advanced technology is suitable for both first-
time users and advanced practitioners, pro-
viding an intuitive user interface, preset treat-
ment parameters, and an integrated history of
successful treatment outcomes.

Glowpin™ by PDO Max (Liverpool, N.Y.) is a

micro-infusion applicator, micro-channeling
device and a professionally engineered der-
ma stamp in a single, compact package. A tip
Before and after two microneedling treatments spaced
lined with 19 evenly spaced 0.5 mm surgical 15 days apart plus application of NCPR by Toskani Med
steel needles attaches to an airless press Photos courtesy of Toskani Med
pump that can hold a topical skin booster of
choice, while the press pump remains under Nutritive Complex Poli Revitalizing (NCPR) by
the control of the user. Glowpin’s primary Toskani Med (Fort Lauderdale, Fla.) is a meso-
function is superficial tissue infusion, using a therapy complex designed to work in tangent
reduced needle length for improved comfort with microneedling to act on the skin’s surface
with zero downtime and a procedure time of and in the deeper layers of the extracellular
20 minutes or less. Thanks to the collagen in- epidermis. Indicated to improve hydration
duction effect, it can treat many patient con- and strengthen the skin’s protective barrier,
cerns, especially when paired with PDO Max NCPR blends HA, vitamins C, E and A, amino
AfterGlo, a polydioxanone and HA skin boost- acids and coenzymes to help revitalize and
ing serum. encourage cell proliferation. According to the
manufacturer, NCPR is clinically tested and
Congela Biocosmetics (Miami, Fla.) incorpo- fragrance free with no declarable allergenic
rates cutting-edge biotechnology and decades ingredients. It is designed to help physicians
of research with JuveXO®, a topical serum that provide immediate skin hydration and long-
harnesses the power of exosomes. Rich in HA, term dermal elasticity through improved col-
collagen, elastin, other essential proteins, and lagen and elastin stimulation thanks to its bioi-
over 100 billion exosomes, JuveXO is a biocos- dentical composition.
metic that targets damaged and aging tissue at
the cellular level with a line of premium topi- PCA Skin® (Scottsdale, Ariz.) is introducing
cal serums designed to significantly improve their dynamic duo Bright & Even Peel and
the appearance of skin and enhance aesthetic HydraBright to combine the power of a profes-
procedures. Launching in 2024 is JuveXO-H sional peel and a daily use moisturizer for imme-
which combines the rejuvenating properties of diate hydration. Their Bright & Even Peel effec-
JuveXO with proprietary recombinant proteins tively brightens and resurfaces skin to improve
specifically for hair. JuveXO-H is a premium uneven tone for all Fitzpatrick skin types with
secretome designed to target common hair key ingredients such as L-mandelic and lactic
concerns, delivering visibly stronger, thicker acid, citrus lemon peel extract, emblica and
and healthier hair. milk thistle. HydraBright includes squalane and
a trio of the brightening actives –
niacinamide, bio-stable gallic acid
and smart melanin microalgae – to
target rough texture and uneven
skin tone. Together, providers can
treat patients both in-office and at-
home for longer lasting and more
dramatic results.

AnteAGE (Irvine, Calif.) is unleash-

ing a new era in aesthetic care with
AnteAGE MDX Targeted Exosomes –
a revolutionary hybrid sourced treat-
ment solution designed to spe-
Before and three months after two microneedling procedures with
JuveXO-H from Congela Biocosmetics applied topically before, during and
cifically target hair regrowth and
after each in-office treatment brightening needs. Each treatment
Photos courtesy of William Gael, MD is infused with 10 billion exosomes,

46 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 Before and one month after one Bright & Even Peel from PCA Skin
Photos courtesy of PCA Skin

sourced from stem cells from bone mar- Love Beauty Pro & Medical (Woburn, Mass.) is
row and umbilical Wharton’s Jelly. MDX Hair excited to announce the newest additions to
Exosomes harness their unique approach to their family, the LC Cell skin and hair products.
enhancing the cell culture conditions resulting The Company’s exclusive U.S. sales, training
in upregulated wingless/integrated (WNT) sig- and distribution teams are ready to bring this
naling. MDX Brightening calls on tranexamic cutting-edge professional product system to
acid and n-acetyl glucosamine for a corrective aesthetic practices with clinical skin and hair
approach to uneven skin tone. solutions that go beyond the treatment room.
Manufactured in the U.S.
and specifically formulated
for physicians, LC Cell takes
human stem cell technology
for the aesthetic world to the
next level with advanced ac-
tive ingredient technologies
and innovative botanically
sourced ingredients. This
blend of science and nature
delivers a continuum of opti-
mal results from the clinical
treatment room to the daily
home regimen.

References:
1. Saul, Derek. Ozempic Sales Up
58% As Drugmaker Novo Nordisk
Nets Record Profits. Forbes
Business, 2 Nov. 2023, www.forbes.
com/sites/dereksaul/2023/11/02/
ozempic-sales-up-58-as-drug-
Before and after treatment with LC Cell from Love Beauty Pro & Medical maker-novo-nordisk-nets-record-
Photos courtesy of Love Beauty Pro & Medical profits/?sh=5e64a91f4bf7.

48 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

NCPR

Nutritive Complex Poli Revitalizing (NCPR)

is a nourishing and revitalizing complex Sofwave
that works on the surface and in the deeper
layers of the extracellular epidermis. It has
Sofwave™ effectively utilizes syn-
a powerful rejuvenating effect with imme-
chronous ultrasound parallel beam
diate hydration action, improving elasticity,
(SUPERB ™) technology, ensuring
firmness, tone and overall appearance of
minimal downtime during a single
the skin. Indicated for bio revitalization, col-
30- to 45-minute session, regard-
lagen stimulation, wrinkle reduction, reduc-
less of skin type. FDA-cleared and
ing signs of aging, deep hydration and cells
clinically validated, Sofwave remod-
nutrition. NCPR has hyaluronic acid which
els collagen and stimulates hyal-
enhances skin hydration, strengthens its
uronic acid production, leading to
protective barrier, and reduces agents that halt
enhancements in facial lines, wrin-
oxidative damage in dermal and epidermal cells,
kles, acne scarring appearance, cel-
vitamins C, E, A and B, amino acids with reparative Booth lulite and elevating the eyebrows,
properties, coenzymes that revitalize and encourage 509
submental and neck regions.
cell proliferation, as well as minerals that shield the
skin from environmental aggressors and rebalance its opti- Sofwave:
mal state. NCPR acts deep in skin cells and the extracellular (855) Sofwave (763-9283) /
matrix thanks to its bioidentical composition. www.sofwave.com
Toskani US:
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Booth
425

JuveXO Booth
231
JuveXO® is a topical serum that has revolution-
ized aesthetics by harnessing the extraordinary power of exo-
somes. Through the most cutting-edge biotechnology and
decades of research, JuveXO delivers a non-invasive and
nonsurgical method to revitalize and rejuvenate by activating
your body’s natural regenerative response. Rich in hyaluronic
acid, collagen, elastin, other essential proteins, and over 100
billion exosomes, JuveXO is a biocosmetic that targets dam-
aged and aging tissue at the cellular level, leaving you looking
as young as you feel. JuveXO delivers a line of premium topi-
cal serums designed to significantly improve the appearance
of skin and enhance aesthetic procedures.
Congela Biocosmetics, LLC.:
(833) 436-8372 / www.Juvexo.com

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 53

 Even-Out Pigment Blaster Skin Smoothie
Body Crème

Even-out textural and pigmented irregularities for vel-

vety soft skin and a transparent glow. Plant extracts
help to remove dead skin cells for a lighter and clari- Booth
225
fied appearance. Multi-active skin lightening agents help
correct unwanted brown spots, melasma, sun damage, skin
darkening and discoloration as hyaluronic acid and shea butter soften
and eliminate rough patches. Safe for face and body (knees, elbows, in-
ner thighs, underarm and mammilla). Comes in 8.8 oz / 250 g with key
ingredients being shea butter, arbutin, kojic acid, vitamin C, niacinamide,
vita blu comple.
Martinni Beauty, Inc.: (888) 440-8811 / www.martinnibeauty.com

AGNES Medical

Agnes RF is an innovative radio- Booth BIOJUVE

frequency (RF) microneedling de- 202
vice focused on selective electro- BIOJUVE™ is a living microbe technology for skin biome care. The Xycrobe™
coagulation to rejuvenate facial skin and technology within BIOJUVE contains a specific strain of a skin native bac-
sculpt focal adiposity. Pioneered by a group of teria, C. acnes defendens. These microbes live on the skin’s surface and
renowned dermatologists, the Agnes device uti- deep within the hair follicles and naturally produce important Bioessentials™
lizes exclusive square wave RF energy, harness- to help optimize skin health and rebalance the skin biome. Bioessentials
ing 1 MHz of energy output, to focus on gentle yet are proteins, fatty acids, polypeptides and antioxidants that help to support
effective procedures while ensuring patient safe- a healthy skin environment, fight oxidative stressors, promote proper skin
ty. Agnes features exclusive single and three-pin hydration, calm the skin, decrease the appearance of erythema and help
needles designed for specific skin concerns and to balance sebum production. BIOJUVE is clinically proven to create signifi-
regions, which allows for complete versatility in cant improvements in the appearance of texture, tone, pore size, fine lines,
treatment options for both patients and providers. wrinkles and photodamage in as little as one week*.
*Results may vary.
AGNES Medical:
(844) 811-1154 / www.iagnes.com Crown Aesthetics: (888) 372-3982 / www.crownaesthetics.com

54 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 Booth
512

Tinted Serum
Broad Spectrum
Viola Threads SPF50+

Bring inner beauty to the outer surface and reverse the appearance of skin The Tinted Serum Broad
age with minimally invasive Viola Threads. Having FDA 510k clearance Spectrum SPF50+ is a
(#K190264) for Polydioxanone (PDO) threads allows Viola Threads to of- ground-breaking zinc superfluid serum created
fer practitioners and other medical professionals competitive pricing. The for superior solar and environmental protection.
Viola line offers a variety of products for applicable treatment areas rang- This hydrating sunscreen is supremely lightweight
ing across the face and body to enhance facial contour, stimulate volume, and complements all six Fitzpatrick skin types by
reverse wrinkles and fine lines, in addition to lifting and anchoring heavier appearing translucent and virtually undetectable
skin tissue and more. Viola Threads offers a signature preparation style with once applied. Its sheer micro-emulsion activates
its packaging and pouches that preserve the efficiency of the thread, ex- a protective shield around cells to build resilience
tending the expiration date up to three years when the pouch remains un- from everyday aggressors, while cultivating a com-
opened and in proper condition. PDO threads are FDA cleared for barbed forted, calm and radiant complexion. It is formu-
sutures and are indicated for use in soft tissue, where the use of absorbable lated with proprietary zinc fusion technology (con-
sutures is appropriate. taining 24% zinc oxide), iron oxides, melanin, ace-
tyl tetrapeptide-22, hydrolyzed keratin, 3D shield
Viola Threads: (213) 351-0001 / www.violathreads.com / [email protected]
technology and 7-dehydrocholesterol. This pro-
vides superlative solar constant protection against
ultraviolet A (UVA), ultraviolet B (UVB), visible light,
infrared radiation and pollution, while reducing
signs of redness, inflammation and strengthening
barrier function.
RATIONALE:
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[email protected]

Booth Plexr
408

Plexr is not a laser, nor an electric cautery, although it appears to

work like one. This new system works simultaneously by an exact
but straightforward scientific principle. PLEXR® technology is globally
recognized for soft surgery, which offers a safe and effective alter-
native to invasive cosmetic procedures with little to no downtime.
Soft surgery provides extraordinary results, which generally could
only be expected after surgeries such as blepharoplasty, facelift
and necklift. During a Plexr treatment, the skin is treated with the so-
called plasma exeresis. Without direct contact with the skin, a small
arc of charged plasma touches the skin point by point. This way, the
skin’s top layer is accurately sublimated (removed).
Med Results: (310) 707-3223 / www.med-results.com

56 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 DR. CYJ iDR/pDR Hair Mist and Mask

DR. CYJ iDR/pDR Hair Mist and Mask are products that work on dam-
aged hair to restore damaged keratin proteins, making hair shiny and soft.
Users can see instant effects within five minutes of using the product, and
the effects last for two to three days. CG-Follicare developed by Caregen,
the main ingredient of the products, has an action mechanism that repair
the S-S bond of damaged keratin protein. It not only prevents damage
when used before frequent dyeing, perming, or drying, but also restores
damaged hair. Because it has been clinically proven to be safe, there
are no side effects, and you can use it with confidence.
Caregen Co., Ltd.:
+8 2314209200 / www.caregen.com / [email protected]
Booth
601

Biointensive GF

As a reactivation corrector for meno-

pausal skin, Vivant’s FF3 Biointensive Booth
GF uses GFP Complex to promote neo- 209
collagenesis, organize collagen fibers
and regulate cell turnover leaving estrogen-depleted
skin feeling plumper. GFP Complex is the novel joining
of vitamin A and growth factor technology with select
amino acids and alpha hydroxy acids to repair the skin’s
support matrix at a cellular level.
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[email protected]

PDO AfterGlo Booth

112
Brighten, tighten and add volume VirtueRF
to the skin with this new polymer skin booster, PDO
AfterGlo, formulated with polydioxanone powder By applying four key value technologies,
and hyaluronic acid (HA). This is a safe and effective VirtueRF reduces the pain of traditional mi-
option for correction of volume loss and rejuvena- croneedling treatment dramatically, while
tion of photoaged skin. PDO powder is comprised at the same time, using comparably higher
of microspheres made from the same material as energy. VirtueRF can deliver either targeted
PDO threads. Suspended in HA and sterile water, tissue coagulation or widen the range of the
these particles are soluble. The serum is then pen- high frequency delivery zone by applying
etrated into the dermis in many ways like micronee- sub-pulses, which eventually enlarges the
dling and microchanneling. It pairs perfectly with area affected. In addition to these four key
Glowpin, a new multi-needle stimulator with airless value technologies and three types of hand-
press pump that infuses any skin booster or serum. pieces, VirtueRF offers five different tips for
PDO Max: a variety of purposes and treatments. By
(800) 670-0225 / www.pdomax.com / eliminating pain and side effects, VirtueRF
[email protected] provides a more comfortable, efficient and
safe experience for our beloved customers.
Cartessa:
(877) 662-2783 /
www.cartessaaesthetics.com /
[email protected]

58 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 StarWalker PQX

The StarWalker® PQX is the newest addition to the StarWalker laser family. What
makes the innovative StarWalker PQX stand out is that it delivers high pico power
and energy, which, combined with a wide range of sophisticated state-of-the art
accessories, offers an exceptional combination of speed and precision in treat-
ments. Picosecond laser technology is an effective tool for efficacious skin pigment
removal without damaging surrounding tissue or causing unwanted side effects.
Additionally, picosecond laser pulses induce skin remodeling in a photoacous-
tic, completely non-thermal way, making it a very safe option for all skin types.
With just one device practitioners can now safely and effectively offer a wide
range of treatment possibilities such as pigmented lesions, acne scars revi-
Booth sions, treatment of wrinkles and tattoo removal.
521
Fotona: (972) 598-9000 / www.fotona.com/us

DP4

The DP4 microneedling pen from Dp Derm is an

advanced fractional micro-channeling device. FDA
cleared for treating facial acne scars, it offers a
dedicated scar treatment (ST) setting. The DP4 is
also the first fully digital device, combining blue- LifeViz
tooth, radiofrequency identification (RFID), dual
power and turbo-cut battery systems to offer a
fast and efficient microneedling treatment. With Our full range of three dimen-
the ability to create up to 1,920 micro-channels sional (3D) LifeViz® systems allows
you to digitalize your consultations Booth
per second, large areas can be treated faster, 220
with exceptional outcomes and minimal dis- and communicate more effectively
comfort and downtime. Each 16-needle car- with your patients through 3D images.
tridge features multiple anti-contamination Portable and compact by design, each of our cam-
seals, and an integrated RFID chip which eras achieves remarkable results for face, body
allows for continuous calibration to ensure and breast. Our premium product range heralds a
precise, reliable and drag-free needle new era for 3D aesthetic photography. The wireless
penetration. LifeViz Pro series integrates artificial intelligence to
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Dp Derm: cious staff time. Using the latest hybrid camera and
(305) 552-0550 / automatic detection, classification of image sets
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it the gold standard in 3D photography. It has a vari-
ety of benefits, from optimizing your daily workflow,
Booth saving valuable time, to generating outstanding be-
109 fore and after images in 3D. The LifeViz Pro range is
designed to let you focus on what really matters –
your patients.
Quantificare, Inc.:
(888) 678-4450 / www.quantificare.com

60 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

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im-aesthetics.com
 The World of Longevity “Several companies are investing in various
Patients are spending time, energy and money aspects of healthy aging, including advanced
to live as healthily as possible for as long as pos- diagnostics, which involve the microbiome,
sible. Research shows that 41% of Americans are genetics, genomics and lab-developed tests
willing to take preventative measures, including and panels on autophagy, neurotransmitters
adequate sleep, healthy meal planning and tak- and detoxification,” Dr. Tager pointed out.
ing supplements and vitamins to solidify living as “Many nutritional companies are making ad-
long as conceivable.1 “The desire for increased vancements in formulations, which include
longevity is driven by a globally connected world digestive enzymes, probiotics, senolytics, col-
offering more opportunities for personal growth lagen, hormonal support for estrogen domi-
and exploration,” shared Rahi Sarbaziha, MD, an nance, sleep and cognition.”
integrative aesthetics physician in Beverly Hills,
Calif. “As science and technology improve, and There is also Altos Labs, Amazon CEO Jeff
Rahi Sarbaziha, MD the collective understanding of interconnected Bezos’ anti-aging start-up, which is set on find-
Integrative Aesthetics possibilities grows, patients have more tools to ing ways to extend human life, slow biological
Physician prolong life.” aging and create eternal living by biologically
Beverly Hills, CA
reprogramming cells in the lab.3
According to Mark Tager, MD, chief executive
officer (CEO) of ChangeWell Inc. (San Diego, Even prestige beauty giants like Dior are
Calif.), baby boomers have adopted healthier claiming their piece of the pie. “Dior Science,
lifestyles. “They are maintaining their fitness with LVMH Recherche, has been a pioneer
and are concerned with diet. They are not on markers of aging,” Ms. Couturaud shared.
going quietly into the night.” With that stance “Dior Science discovered that the anchoring
on aging comes a major money dump into proteins of epidermal stem cells in the dermal-
Mark Tager, MD the age-reversing industry, with the U.S. in- epidermal junction decrease with age, lead-
CEO
ChangeWell Inc.
vesting an estimated $5.2 billion into longev- ing to a slowdown in cell renewal and an ac-
San Diego, CA ity in 2022.2 celeration of the signs of aging.” A pioneer in
inflammaging, she added that Dior Science
A Multi-Billion Dollar Industry has made it possible to understand the role of
Over the last five years, the anti-aging field immune cells and the consequences of their
has witnessed heavy research, the advent activation. Dior’s approach is to connect the
of start-ups, and an increase in dedicated territories of longevity research to reach new
conferences on the topic. “Beyond living milestones, transforming scientific promises
longer, the common objective is to reduce into future solutions for beauty and health.
Virginie Couturaud the number of illnesses,” said Virginie
Couturaud, scientific communication
Scientific Communication
Director director at Christian Dior (Paris, France). “Researchers have demonstrated
Christian Dior
Paris, France
“Researchers have demonstrated that
biological age fluctuates, and it is re-
that biological age fluctuates, and
versible whether naturally or with the it is reversible whether naturally
help of molecules.”
or with the help of molecules.”
Physicians and the medical community
are working to slow aging, so patients feel Human Aging 101
and look better. According to Pamela Smith, The inherent aging process affects every in-
MD, founder and director of the Center for dividual, yet this complex and multi-factorial
Pamela W. Smith, MD Precision Medicine (Gross Pointe Farms, progression consists of biological and physi-
Founder and Director
Center for Precision
Mich.), the American Academy of Anti-Aging ological changes, including permanent shifts
Medicine Medicine (A4M) is leading global physician in metabolism, hormone levels, sleep patterns,
Gross Pointe Farms, MI education on reversal of aging. well-being and the skin.

66 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 Genomics “Naturally occurring hormonal declines affect
Every patient’s genetics and deoxyribonucleic physiological and biological aging externally
acid (DNA) patterns account for about 25% of and internally,” Dr. Smith said. “Hormonal aging
aging and life span. Lifestyle choices influence on the skin causes thinning, atrophy, dryness,
the remainder. “The most commonly echoed wrinkling and delayed wound healing. A de-
phrase is that ‘genetics loads the gun, but life- crease in sex steroids also reduces skin func-
style pulls the trigger’,” Dr. Tager shared. “Genes tions under hormonal control, including kera-
need to be turned on to have an effect. This is tinocytes, Langerhans’s cells, melanocytes,
the role of epigenetics and how stress, diet and sebaceous glands, collagen content and hyal-
lack of exercise switch genes on or off.” uronic acid synthesis,” she added. “The most
important thing patients can do to improve
Dr. Smith explained that genomics influences their skin is implement customized bio-identi-
aging in several ways. “The most important cal hormone therapy. It is the key component
factor is the ability of the body to methylate in helping patients age gracefully.”
properly, which is inherited by several genes,”
she mentioned. “Approximately 50% of the
world’s population are poor methylators. “Genes need to be turned on to have
Fortunately, nutritional therapies and other
treatments improve methylation.” an effect. This is the role of epi-
 Epigenetics
genetics and how stress, diet and lack
Genetics are responsible for certain age-relat- of exercise switch genes on or off.”
ed hereditary conditions. However, when phy-
sicians dial into behavioral and environmental
influences, they can alter the genome through According to Dr. Tager, more recent advance-
epigenetics to control and improve aging, Dr. ments include advances in hormone testing – a
Sarbaziha shared. key metric in aging. “Companies like Ayumetrix
now offer salivary hormone and fingerstick nu-
Popular epigenetic therapies include DNA trient tests. Precision Analytical employs dried
methylation, histone modification, chromatin urine to measure hormone metabolites in their
remodeling and ribonucleic acid (RNA) modifi- Dutch test, and Prolon, which pioneered the
cation to slow aging and thwart certain diseas- fasting-mimicking diet, is paving the way with
es by reversing genome function. “Epigenetic therapeutic approaches to healthy aging.”
studies have shown positive for altering pa-
tient behavior and improving their environment  Gut Health
to decrease the risk of developing diseases,” “Your gut is the second most important bodily
Dr. Smith stated. system that maintains health as patients age,”
Dr. Smith said. “The gastrointestinal (GI) tract
 The Endocrine System comprises 70% of the immune system and
The endocrine system may be the most instru- makes 90% of the body’s serotonin. Biotin,
mental bodily system for aging and longevity. the vitamin B, responsible for healthy hair and
It is responsible for various life processes such nails, is also made in the GI tract.”
as memory, decreasing the risk of diseases like
cancers, diabetes, heart disease, vision, mobility, Over time, the healthy microbes that live in the
adequate sleep functionality, libido and energy GI tract can become diluted, making it difficult
levels. As Dr. Sarbaziha explained, diet, lifestyle for the body to defend itself and limiting the
and genetic predisposition can influence the production of essential vitamins and other vital
dysregulation of the endocrine system. With age, chemicals. Ultimately, an imbalance in the gut
decreased hormone secretion levels impact the microbiome negatively impacts the immune
endocrine system, affecting homeostasis. system’s ability to function correctly.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 67

 Gut health is pivotal for nutrient absorption and Integrating Age-Reversing Treatments
well-being, and to maintain it, a wholesome, into a Medical Practice
clean diet with fiber-rich whole foods, as well as Patient demand for age-reversing treatments
fermented foods and probiotics in pill or powder and therapies prompts practitioners to incorpo-
form, improves the gut for prolonged healthy ag- rate them into their aesthetic practices. In Feed
ing. A study in Nature Metabolism revealed that Your Skin Right by Dr. Tager, he defined a new
adults with a diverse mix of gut microbes over type of practice – integrative aesthetics – which
their lifetime displayed lower cholesterol levels, consists of “personalized assessments, treat-
reduced frailty and more beneficial blood chem- ments and counseling that recognize skin health
icals, contributing to increased longevity.4 and beauty as highly dependent upon multiple
organ systems that are affected by ‘omics,’ life-
style, and environment. Cash-pay patients are
“Your gut is the second most important interested in more whole-person / root-cause
healthcare and want to look good as they age.”
bodily system that maintains health as
patients age. The gastrointestinal (GI) tract An easy starting point is suggesting diet, exer-
cise and stress management changes. Then,
comprises 70% of the immune system and Dr. Tager recommends personalized nutritional
makes 90% of the body’s serotonin. Biotin, supplementation via advanced diagnostics. To
grow a practice, physicians can learn about in-
the vitamin B, responsible for healthy hair tegrative medicine or, as Dr. Sarbaziha shared,
partner with other practitioners and adopt the
and nails, is also made in the GI tract.” ‘blue zone lifestyle’ as part of their brand to po-
sition themselves as holistic health advocates.

The Next Wave of Aging Research and “With the new wave of integrative aesthetic
the Future practices, practitioners recognize the signifi-
Aging research continues to forge forward. The cance of internal and external aging processes
fundamental solutions to living a healthier, longer for comprehensive well-being,” Dr. Sarbaziha
life are still popular, albeit improved. Stem cell and elaborated “The connection between revers-
gene treatments continue to be prevalent, yet are ing aging and aesthetics is evident in the shared
more accessible with broader applications, and interest in addressing internal and external as-
new innovations continue to gain recognition. pects of aging.”
References:
Ms. Couturaud said age-related interventions,
1. Mikhail, A. (2023, August 16). Wealthy Americans will go to the
such as Yamanaka factors, which reverse ag- extreme to live longer, from downloading their brains to taking
ing without cells losing their identity, and risky drugs. Fortune Well. https://fortune.com/well/2023/08/10/
wealthy-americans-extreme-measures-to-live-longer/
Metformin, which limits the incidence of cancer 2. Annual longevity investment report archives. Longevity.
and Alzheimer’s disease, prove that molecules Technology. (n.d.). https://longevity.technology/investment/
seem promising for reversing cellular aging. report/annual-longevity-investment-report/
3. Jimenez, D. (2021, September 16). Billionaires are
betting on anti-ageing research, but can ageing
In addition, senolyctic drugs are on the hori- really be cured? Pharmaceutical Technology. https://
zon, eliminating cells that no longer divide and www.pharmaceutical-technology.com/features/
billionaires-anti-ageing-research/?cf-view
function properly. Dr. Tager cited reprogram- 4. Godman, H. (2023, July 18). Healthy Gut, healthier aging.
ming strategies and aging vaccines as emerg- Harvard Health. https://www.health.harvard.edu/staying-
healthy/healthy-gut-healthier-aging#:~:text=In%20a%20
ing interventions. “Other interventions include study%20published%20online,change%20in%20their%20
the nicotinamide adenine dinucleotide (NAD+) gut%20microbiome
precursors in epigenetic regulation and DNA Mikhail, A. (2023a, April 6). Dior is getting into the trendy
reverse-aging business. here’s how its team of expert
repair, sirtuin-activating compounds, resvera- researchers plans to help people look younger. Fortune Well.
trol and rapamycin.” https://fortune.com/well/2023/04/06/dior-reverse-skin-aging/

68 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

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 CLINICAL JOURNALING WITH TAG:
Frontiers in
Aesthetic Medicine:
Advancements for
the Future
By Kevin A. Wilson, Contributing Editor

At its best, peer-reviewed science is the bedrock upon

which the industry is based. New information becomes new
technology. To loosely quote Plato, “need is the mother of
invention” (or innovation), and today’s emerging aesthetic
technologies are intended to meet existing and emerging
needs, as well as challenges. This ballet unfolds in the pag-
es of journals, where rigorous examination separates the
theoretical from the factual.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 73

 EFFICACIOUS ANTIOXIDANTS AND VITAMIN C:
A NOVEL FREE RADICAL DEFENSE APPROACH
Among existing needs is the well-established powerful, plus this elastin-conserving vitamin C,
field of skincare, where decade-by-decade versus a similar formulation with traditional vita-
Alan D. Widgerow, advancements look like leaps along a trail that min C. Once we validated that the formulations
MBBCh, MMed has literally been trod for thousands of years. had equivalent antioxidant effects, we subject-
Division Chief of Research
Center for Tissue Yet, the science behind skincare is often sus- ed an ex vivo skin model – three skin explants
Engineering at pect because regulatory rules do not require from facelift procedures – to each topically ad-
University of the same scientific rigor as drugs and medical ministered formulation to compare the effect of
California Irvine
Irvine, CA
devices are subject to. A recent study 1 in the each on elastin.”
Journal of Cosmetic Dermatology elucidates
the groundwork for and rationale behind a po- Detailed in the study text are the extensive for-
tentially game changing formulation in the fight mulations. Differing only in the vitamin C used,
against free radical damage with two experi- the evaluated preparations were applied to
ments. The combination of antioxidant actives treat human skin cultures for 48 hours before
consists of a variety of proven players, as well being subjected to oxidative stress – a dose
as a vitamin C derivative sodium salt which, in of 13 J/cm2 ultraviolet (UV) radiation – then re-
contrast to the oft utilized vitamin C/L-ascorbic treated and incubated for another 24 hours
acid variants, preserves rather than inhibits the (total 72 hours of treatment). According to the
presence and neogenesis of elastin. study, the generation of free radicals was then
semi-quantitatively measured. The result was a
Alan Widgerow, MBBCh, MMed, division firm demonstration of strong efficacy, but more
chief of research for the Center for Tissue importantly, equivalence between the two for-
Engineering at the University of California mulations in their ability to fight the effects of
Irvine (Irvine, Calif.) is lead author of the ar- free radicals.
ticle. “Any dermatologist can tell you that a
large volume of reactive oxygen species is
generated on a daily basis stemming from “Research began to
photodamage and other stressors that are
applied to the skin, wear and tear, and other surface suggesting that the
extrinsic causes, resulting in free radical dam-
age which the body is constantly combatting,”
traditional vitamin C,
he explained. “Vitamin C, a backbone of cos- L-ascorbate, was causing
meceutical preparations, was the first original
quencher of these reactive oxygen species.
damage to elastin, and
So, it has taken a key leading role in cosme- nobody had looked
ceuticals over the years – even as many al-
ternative antioxidants have emerged – in our at vitamin C from that
efforts to bolster and maintain skin health.”
perspective.”
While the community has always regarded vi-
tamin C as a stimulant of collagen and a solid During the ex vivo skin model experiment,
antioxidant, which it is, nobody had looked at plastic surgeons donated the skin used. “This
what happens with elastin, a vital element with- was unique because the explant skin was real,
in the extracellular matrix. “Research began to photodamaged skin which is a perfect model
surface suggesting that the traditional vitamin for examining exactly what effect these formu-
C, L-ascorbate, was causing damage to elas- lations would have on collagen, elastin, etc.,”
tin, and nobody had looked at vitamin C from Dr. Widgerow said. “It was our belief that the
that perspective,” Dr. Widgerow continued. preparation with the vitamin C sodium salt de-
“This caught our attention and generated a lot rivative would perform better as far as elastin
of interest. We also noticed a discovery out of preservation was concerned.”
Canada that vitamin C sodium salt derivatives
actually conserved elastin. So, first we set out After the explants were subjected to topi-
to validate an antioxidant formulation we creat- cal treatment with the formulations daily for 7
ed using recognized antioxidants known to be days, the skin underwent immunofluorescent

74 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

staining, followed by software analysis of cap- vitamin C based topicals. So, it is an ideal com-
tured images. The results were striking. “We bination for an antioxidant formulation because
did find that in fact, the traditional L-ascorbate it has efficacy in the antioxidant sphere, it stimu-
did create a moth-eaten appearance in the lates collagen, and it stimulates elastin. And that
elastin. In other words, it seemed to actually is beautiful. What’s more, we are not only look-
degrade some of that elastin, whereas the ing at potential applications in normal skincare,
preparation with the sodium ascorbate we which it should work wonderfully for, but also in
were using seemed to conserve the elastin.” a post-procedure adjunctive role. The possibili-
ties are exciting, to say the least.”
This led to the next step, a deeper evaluation of
the sodium ascorbate formulation, in a more re- Reference:
cent study in press, to see if it might actually stim- 1. Widgerow, AD, Ziegler, ME, Garruto, JA, Shafiq, F.
ulate elastinogenesis. Dr. Widgerow stated that Antioxidants with Proven Efficacy and Elastin-Conserving
the preliminary results appear to be extremely Vitamin C – A New Approach to Free Radical Defense. J
favorable. “We seem to have a breakthrough Cosmet Dermatol 2023; 22: 3320–3328.
here, where we go one better with sodium
Editor’s Note: The original article Antioxidants with Proven Ef-
ascorbate and preserve – or even stimulate – ficacy and Elastin-Conserving Vitamin C – A New Approach to
elastin, when for a long time we have been Free Radical Defense, is open access and available online at:
having a deleterious effect on elastin with our https://pubmed.ncbi.nlm.nih.gov/37853849/

GENDER-AFFIRMING FACIAL SURGERY:

ADULT 3D FACIAL MORPHOLOGY DIFFERENCES
With the more normalized acceptance of fluid- (Walnut Creek, Calif.). “Although there is a rea-
ity in gender identity, comes an unsurprising sonable amount of data in the two-dimension
concurrent rise in demand for what has been (2D) realm, the question of facial femininity Rahul Seth, MD, FACS
Facial Plastic and
termed gender-affirming facial surgery (GFS). versus masculinity is a fundamentally three- Reconstructive Surgeon
Making a face more masculine or feminine plays dimensional assessment. We knew there was Division of Facial Plastic and
a key role in the expression of a new gender a lot to be gained in growing that overall un- Reconstructive Surgery
choice. The fundamental aspects of facial ap- derstanding. Through previous research, we Department of
Otolaryngology-Head and
pearance that characterize masculinity or femi- have begun to understand that certain areas
Neck Surgery at University
ninity are basically understood and defined of the face are more influential in the brain’s of California San Francisco
subjectively, but there is little objective data to perception and categorization of somebody’s Golden State Plastic Surgery
drive surgical decision making in these cases. gender, but understanding in 3D how the face San Francisco and Walnut
Emerging technology is being adapted to meet and its regions display sex-characteristics was Creek, CA
this developing need. A recent study1 published less understood.”
in Facial Plastic Surgery & Aesthetic Medicine
elucidated the use of digital imaging and soft- Study authors selected a subset of 1,573 facial
ware analysis to provide a more objective ap- surface scans of healthy subjects from a much
proach to better defining, in three dimensions larger U.S.-based repository of 3D facial scans
(3D), what surgical interventions would shift a and demographic information (collected be-
given face toward a more masculine or feminine tween 2009 and 2014). For inclusion, facial scans
ideal. In other words: Objectively, what makes a were to be of subjects 20 years of age or older
face more masculine or feminine? at the time of imaging with no known congeni-
tal facial abnormalities or history of facial trauma/
“We have not seen robust objective facial data facial surgery. Also, gender was self-identified
in the 3D realm,” said Rahul Seth, MD, an au- as either female or male and confirmed via ge-
thor of the above-mentioned article from the netic analysis of saliva samples. In order to re-
Division of Facial Plastic and Reconstructive duce confounding variables, only participants of
Surgery, Department of Otolaryngology-Head European-Caucasian ancestry were included.
and Neck Surgery at University of California Each scan was then landmarked by trained hu-
San Francisco (San Francisco, Calif.). Dr. Seth man observers according to a scientifically-vali-
also practices at Golden State Plastic Surgery dated system of 24 landmarks. The magnitude

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 75

 of differences in various aspects between male morphing. This may provide practical, data-
and female faces was then determined by soft- driven guidance for making the face look better,
ware. “Simply put, we took 3D facial scan data younger, or more towards a specific gender.”
and used mathematical software analysis to re-
veal the type and magnitude of facial differences As supplementary information to guide under-
between males and females.” The key to this is standing, software-generated visual represen-
geometric morphometrics (GM), a series of math- tations were then manipulated using this data
ematical operations which translates nuisance to morph a face toward more masculine and
biometric scanning differences into interpretable, feminine extremes. This is demonstrated by
and thus practically representable, information. the example in Figure 1 (Figure 3 from original
“GM is a science for understanding how differ- paper). The use of morphing technology to vi-
ent 3D points relate to one another. It is a compli- sualize potential changes in a digitally scanned
cated process, but we can boil it down to three patient face is a common practice, but there is a
characteristics: Size, shape and form (a combi- challenge – and a responsibility – in translating
nation of size and shape),” Dr. Seth explained. what may be generated on a computer screen
into what is surgically achievable. “Facial morph-
Results were extraordinary. While the article it- ing includes the conceptualization, visualization
self provides and dives more deeply into the and explanation of the proposed changes, all
details, the differences that drive our perception of which lead up to inform surgical execution,”
of gender account for only 6% of facial shape Dr. Seth noted. “It is up to the surgeon to use
variance, but 30% of facial form variance, when technology responsibly in the consult, to know
objectively analyzed. “We think of prominent what they can and cannot do as a surgeon, and
features such as the area between the eyes, the to accurately represent these realities to the pa-
prominence of the brow, or shape of the nose tient in any case, before they undergo surgery.”
to portray gender, but there are many more
subtle differences that, together, help make the In the seemingly large sample size, the dis-
whole face more masculine or feminine,” he tinct lack of ethnic diversity was a notable
continued. “This kind of information may help limitation of the study, but necessary at that
surgeons optimize intervention for GFS. The stage of the game, according to Dr. Seth. “We
possibilities this enables compelled us to form had to limit the study to lend a more homo-
a company (Deep Surface AI in Calgary, Alberta, geneous analysis and make things a bit sim-
Canada) and build a Health Insurance Portability pler at first. Within the facial data we worked
and Accountability Act (HIPAA) compliant com- with, there is a broader representation of eth-
mercial software platform to help the commu- nic variety. We do have an expanded dataset
nity with visual representations and software which we expect to publish in the future.” A
sneak peek at that information? “Our data for
this study we are discussing now suggests,
among other things, that our perception of
gender-related facial differences is much
more profound than the actual objective dif-
ferences,” he asserted. “We still have more
work to do with the expanded dataset, but
similarly, the objectively measured differenc-
es due to ethnicity are much less significant
than our perception of them would suggest.
Overwhelmingly, and simply put, we are much
more alike than different.”

Reference:
1. Bannister JJ, Juszczak H, Aponte JD, et al. Sex Differences
Figure 1: Top: An example subject (center column) that in Adult Facial Three-Dimensional Morphology: Application
has been transformed to have a more masculine (right) to Gender-Affirming Facial Surgery. Facial Plast Surg Aesthet
Med 2022;24(5):363–368.
and more feminine (left) shape, leaving overall size
unchanged. The shape distance between each column
is equal to the magnitude of the shape distance between Editor’s Note: The original article Sex Differences in Adult Fa-
the averaged female and male facial shapes. Bottom: The cial Three-Dimensional Morphology: Application to Gender-
same shape transformation process applied to the nose Affirming Facial Surgery, is open access and available online at:
region of the same subject. https://pubmed.ncbi.nlm.nih.gov/35357226/

76 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 A GLOBAL AESTHETIC
MEDICINE NETWORK

Where Education is Opportunity

IM-Aesthetics (Informa Medical Aesthetics) is a global,

multi-channel resource for medical aesthetics
that advocates for the continuing education
of practitioners worldwide and provides a space
for the market to come together.

www.im-aesthetics.com

OUR
PORTFOLIO
OF BRANDS:

IN SCIENTIFIC PARTNERSHIP
WITH THE
Injection of dermal fillers is a relatively safe pro- some signal upon passage into a blood ves-
cedure, but adverse events (AEs), including se- sel are widely available, we will be inherently
rious ones like vascular compromise and isch- injecting blind.
emic complications, do occur. While filler com-
plications can occur anywhere on the face, the While aspiration is a widespread practice,
nose is the most dangerous area of the face there is no definitive evidence showing effec-
to inject filler with AEs that can be devastating. tiveness in preventing complications. In fact,
there is a growing consensus among expert
Considering the global surge in demand for injectors that aspiration is not only unreliable,
nonsurgical rhinoplasty (NSR) it is more impor- but actually decreases safety.3,4 It is unreliable
tant than ever that NSR injectors have a detailed because the test is only assessing the exact
understanding of nasal anatomy, a nuanced ap- spot where the tip of the needle is located
preciation of nasal aesthetics, and a thorough during aspiration, not necessarily where the
knowledge of best practices in prevention, rec- product is injected. This maneuver assumes
ognition and treatment of AEs. Adoption of and that the injector’s hand has remained perfectly
diligent adherence to the UISP described in this still through the performance of aspiration and
manuscript are key to prevention. subsequent injection. If the tip of the needle
moves, even by a millimeter, the test is ren-
Injection safety in the nose hinges primarily on dered useless. As demonstrated by a recent
preventing and managing ischemic complica- ultrasound study, it is physically impossible to
tions. Although bruising, erythema, tenderness aspirate a viscous gel, like those used for fa-
and swelling may occur, these are transient and cial filling, without moving the tip of the needle
treatable with over-the-counter medication and several millimeters during the procedure.4,5
vascular lasers. In addition, moderately serious
AEs like granuloma and delayed onset of nod- Considering the size of the vessels to be avoid-
ule formation that occur with filler injection in ed, this distance is clearly far too large to en-
other areas of the face have not been reported sure safety during product placement. Of note,
after using FDA-approved fillers in the nose.1 some have argued that aspiration without mo-
tion is possible if the needle is resting on bone.
Overall, the principles that govern safe injec- This may be true for a brief suction time, but it
tion in the face can be applied to NSR; how- is very unlikely true for the extended times sug-
ever, meticulous following of those principles is gested by the aspiration literature as necessary
of paramount importance with nasal injections. for a reliable test, especially when using the
There are numerous reviews and reports of fill- highly viscous fillers needed for good NSR out-
er-related blindness and tissue necrosis, which comes.6 False negative findings with aspiration
firmly illustrate this point.2 are common enough7,8 to suggest the practice About
itself creates a false sense of security for injec- the Author
Vascular complications occur when the tip of tors, which could lead to the placement of large
the needle or canula is inside an artery and a amounts of filler under high pressure inside
large amount of filler material is injected un- a patient’s artery. Until technology provides a
der high pressure, obstructing critical blood way to detect arterial puncture, one must inject
supply to the skin or the eye. The only excep- assuming that their needle or cannula is always
tion to this rule is in the tip of the nose or the inside a vessel.
alar area, where ischemia can occur because Alexander Z. Rivkin, MD
too much filler compresses the small ves- If we cannot know whether a needle is Dr. Rivkin is an aesthetic
sels in a tight space, causing a compartment in a vessel, what can be done to ensure surgeon in private
syndrome-like effect. Therefore, preventing safe injection? practice in Los Angeles,
complications hinges on preventing the con- Though there are no randomized clinical trials Calif. He is also assistant
clinical professor at the
fluence of these factors. on the subject, there are evidence-supported David Geffen UCLA
practices that can reduce risk. First, one must School of Medicine.
Is there a way to make sure that the tip do everything possible to limit the volume He is a member of the
of the needle or cannula is not inside of filler deposited in any one injection point. International Society for
an artery? Aesthetic Competence –
Because one must assume that the needle a leading consortium of
Unfortunately, the short answer to that ques- tip is always in a dangerous place, injecting a global aesthetic experts
tion is – no. Until ‘smart’ needles that provide large bolus of filler is an unsafe practice under devoted to safety.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 81

 Figure 1:

51-year-old male went through facial feminization with a history of three rhinoplasty surgeries, last surgery was one year prior
to consultation with Dr. Rivkin; patient requested to turn up their nasal tip with Bellafill.
(A) 0.25 cc Bellafill was injected into their tip using a backloaded 0.5 cc 28-gauge insulin syringe.
(B) A 1 cm area of duskiness developed on their tip ten minutes after injection that was concerning for compressive ischemia.
(C) Asprin was given, and massage and warm compress were administered for 15 minutes. The area was still dusky
afterwards, so the patient started on a Medrol dose pack and given nitric oxide (NO) gas, nitropaste, hyaluronidase
injection (50 u) and continued receiving massages and heat. They left the clinic after an hour improved but returned the
following day.
(D) The next morning the nasal tip looked like it was developing necrosis. They were given nitropaste and NO gas for an
hour and injected with 30 u more of hyaluronidase. They were then sent for hyperbaric oxygen (HBO) treatment. Their tip
began to improve.
(E) and (F): The next day they were treated with HBO a second time. Throughout this period the patient was using aspirin,
nitropaste, warm compresses, massaging the area and Medrol dose pack at home.
(G) After the second HBO treatment the patient showed clear signs of improvement and by day 5 post treatment their nasal
tip skin recovered completely.

any circumstance. Admittedly this position con- motion limits the amount of filler deposited
trasts with many of the recommendations and in any one place to a very small amount.
techniques popular today and it is not uncom- This practice is more reliable than aspira-
mon to read claims that bolus injections on tion because, even if the needle is inside a
periosteum or perichondrium are ‘safe’. The vessel, it will exit the vessel before enough
literature on anatomic variability, however, pro- material has been deposited to cause an
vides clear evidence that doing so is unwise. AE. If the injection is placed as a vertical
column, this practice also improves tis-
Given the absence of any true ‘safe plane’ for sue lift because expanding multiple tissue
injection, it is best to take appropriate precau- planes leads to more efficient and precise
tions. The sections below describe the UISP projection.
set of protocols developed by Dr. Rivkin. These • Slow, low-pressure injections give the injec-
principles should be applied in combination with tor time to react if early signs of ischemia
adequate training and knowledge of anatomy. present. This type of injection also will not
overcome systolic blood pressure, which
Universal Injection Safety Precautions: is required for a filler to move retrograde
• Continuous retrograde motion as filler through an artery.
is moving through the needle. Constant • Injectors should use the smallest gauge

82 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 needle possible. A small needle gauge en- cannula from entering a vessel. We enter ves-
courages small injection volumes and en- sels all the time when we inject filler, as is obvi-
hances patient comfort. ous from the frequency with which we cause
• Cannulas should be 25G or larger. Sizes bruising. The goal is to make sure that, no mat-
smaller than 25G can pierce vessels, but this ter where the tip is, we never inject enough
must be balanced against the fact that larger filler to cause an ischemic AE.
cannulas can compromise precision, which is
especially important in the nose.
• Diligent cleansing of the skin with alcohol, Do you know what to do if you suspect an
chlorhexidine or hypochlorous acid is im- ischemic event or if your patient is experi-
portant because fillers can remain under the encing changes in vision? Read the original
skin for several years. We want to prevent article titled: Clinical Pearls for Optimising
the formation of an environment likely to har- Safety in Non-Surgical Rhinoplasty at:
bor chronic infections. https://www.prime-journal.com/prime-
journal-may-june-2023/ page 28
UISP Specific to NSR:
• Ice the skin of the nose prior to injection. This
will shrink the vessels and decrease the risk References:
of perforation. One exception is patients who 1. Wang JV, et.al. Utility of preinjection aspiration for
have had rhinoplasty in the past, as their der- hyaluronic fillers: a novel in vivo human evaluation. J Cutan
mal blood supply is already compromised. Med Surg. 2020; 24(4): 367- 371.
For these patients, icing may increase the 2. Beleznay K et.al. Update on avoiding and treating blindness
from fillers: a recent review of the world literature. Aesthet
risk of ischemia. Surg J. 2019; 39(6): 662- 674.
• Use 0.3 cc or 0.5 cc insulin syringes back- 3. Rivkin AZ. Aspiration: I don’t do it and neither should you. J
loaded with filler. These syringes come with Cosmet Dermatol. 2021 Apr;20(4):1042- 1043
smaller needles (28G to 31G) and permit the 4. Goodman GJ et.al. Aspiration Before Tissue Filler-An
precise deposition of tiny (0.01 cc to 0.03 cc) Exercise in Futility and Unsafe Practice. Aesthet Surg J. 2022
Jan 1;42(1):89-101.
amounts of product. Insulin syringes improve
5. Lin F, et.al. Movement of the Syringe During Filler
safety by limiting the amount of product in- Aspiration: An Ultrasound Study. Aesthet Surg J. 2022 Sep
jected per spot. The outcome is improved 14;42(10):1109-1116.
because of an increase in precision. They 6. Kapoor KM et al. Factors influencing pre-injection aspiration
also improve patient comfort. Aspiration is for hyaluronic acid fillers: a systematic literature review and
meta-analysis. Dermatol Ther. 2020;e14360.
not possible with these syringes due to nee-
7. Torbeck RL et.al. In Vitro Evaluation of Preinjection Aspiration
dle size and syringe construction. for Hyaluronic Fillers as a Safety Checkpoint. Dermatol Surg.
2019 Jul;45(7):954-958.
Additional suggestions to improve safety 8. Van Loghem JA et.al. Sensitivity of aspiration as a safety test
for nasal injections include: before injection of soft tissue fillers. J Cosmet Dermatol. 2018
Feb;17(1):39-46.
• Place most injections at the midline, as the
9. Murray G, et.al. Guideline for the Management of Hyaluronic
major vessels of the nose mainly run on the Acid Filler-induced Vascular Occlusion. J Clin Aesthet
lateral aspects. However, there are vessels in Dermatol. 2021 May;14(5):E61-E69. Epub 2021 May 1.
the midline, and anatomic variability dictates 10.Jones, D et.al. Preventing and Treating Adverse Events
that some people will have a dorsal nasal of Injectable Fillers: Evidence-Based Recommendations
From the American Society for Dermatologic Surgery
artery which runs down the middle of the Multidisciplinary Task Force. Dermatologic Surgery 47(2):p
dorsum. Careful adherence to the UISP rules 214-226, February 2021.
is necessary, even in the midline. Advanced 11. Rommel F et.al. Evaluating Retinal and Choroidal Perfusion
NSR injectors will regularly inject outside Changes After Ocular Massage of Healthy Eyes Using
of the midline, because correction of many Optical Coherence Tomography Angiography. Medicina
(Kaunas). 2020 Nov 26;56(12):645.
asymmetries and cases of cartilage collapse, Fang WT et.al. Descriptive Analysis of 213 Positive Blood
require filling of the nasal sidewall. Aspiration Cases When Injecting Facial Soft Tissue Fillers,
• Pinch-compress the dorsal nasal and supra- Aesth Surg J, Vol 41, Issue 5, May 2021; 616–624
trochlear vessels during radix injection to Rivkin A. Nonsurgical Rhinoplasty Using Injectable Fillers: A
prevent inadvertent cannulation. Safety Review of 2488 Procedures. Facial Plast Surg Aesthet
Med. 2021 Jan-Feb;23(1):6-11.
Rivkin A. PMMA-collagen Gel in Nonsurgical Rhinoplasty
The goal of UISP and the other effective safety Defects: A Methodological Overview and 15-year Experience.
precautions is not to prevent our needle or Plast Reconstr Surg Glob Open. 2022 Aug 19;10(8):e4477

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 83

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Practice Management
Preparing Your Medspa for Sale:
Financial Dos and Don’ts
By Emily Brems

Over the last decade, medspas have emerged • Don’t Overspend. Regularly review and ad-
as a thriving industry that meets the ever- just your expenses to control costs and avoid
growing demand for aesthetic and cosmetic getting into debt.
treatments. But behind these beauty-focused
aesthetic practices, lies a complex financial • Do Consult a Professional. A certified ac-
landscape that is starting to become a topic of countant or financial advisor who knows the
priority for independent owners – especially specific financial issues of the healthcare
those planning an exit. and spa industry can help you prevent and
avoid common errors and provide advice
With the market shifting to more investors, that may help your business succeed.
business owners are finding themselves
prompted for financial statements before they • Don’t Operate Without a Financial Strategy.
are ready to sell. Here are some basic dos and Plan for the long term and set financial goals
don’ts to get you headed in the right direction for your medspa, for example, budgeting for
on your financial statements: investments in new equipment and staff.

• Do Ensure that All Financial Data is Accurate. • Do Monitor Cash Flow Closely. Doing so
If your balance sheet is not up-to-date and helps ensure that you have sufficient funds
reconciled, your profit and loss (P&L) state- to cover operational expenses and expan-
ment may not be correct. Reconcile your sion plans.
financial statements regularly to identify dis-
crepancies and errors. • Don’t Overlook Taxes. Do not forget to set
About the Author aside funds for tax payments and stay up-
• Don’t Wait Until Year End to Make Adjusting dated on tax laws that affect your business.
Entries and Reconcile Accounts. Ignoring
important updates and not keeping accu- • Do Budget. Develop a comprehensive bud-
rate records can lead to financial errors and get to track and control expenses, including
legal issues. rent, supplies and payroll.

• Do Keep Detailed Records. Maintaining de- • Don’t Let Debt Accumulate. Manage loans
Emily Brems tailed records of all transactions, including in- and credit wisely. And, when you do have
Serving as consulting chief
financial officer within voices, receipts and patient information can debt, create a clear repayment plan.
CLA’s health care industry, provide a clear picture of your business per-
Ms. Brems has focused her formance for prospective buyers. Remember that managing the financial as-
career on multi-location pect of your medspa is crucial for its success.
healthcare companies,
including hospital systems,
• Don’t Mix Personal and Business Finances. Following these dos and don’ts can help you
private practice, dental Keeping separate bank accounts and credit maintain a healthy financial foundation for
organizations and in the cards for your medspa and your personal your business.
medspa space. Holding use can make it easier to get an accurate
executive roles, she
picture of your business cash flow, as well as
has successfully scaled
companies through de take advantage of tax deductions and ben-
novos, effective integration efits come tax time.
of mergers and acquisitions Editor’s Note: The information contained herein is general in na-
as well as organic growth. • Do Provide Category Details. Providing de- ture and is not intended, and should not be construed, as legal,
She strives to help clients accounting, investment, or tax advice or opinion provided by
identify opportunities for
tails for your revenues and expenses by ser- CliftonLarsonAllen (CLA) LLP (CliftonLarsonAllen) to the reader.
market growth, diversification vice line can help your businesses profitabil- CLA is an independent network member of CLA Global. See
and product development. ity be calculated more clearly. CLAglobal.com/disclaimer.

86 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

Women in Aesthetics Mariangel Acevedo, MD:
Making Patient Beauty an Art Form
By Jessica Barry, Contributing Editor

Mariangel Acevedo, MD, was not originally At 25 years old, Dr. Acevedo began working
drawn to a career in medicine. “From a young in general medicine and soon developed anxi-
age, I wanted to act, sing and travel the world,” ety and depression, irritable bowel syndrome,
she shared. “I loved the idea of being a differ- tachycardia and migraines. She also experi-
ent person every day and wanted to tell stories enced significant weight gain and two bouts of
about love, life and different experiences.” bronchitis in one year.

Then, a strange dream set Dr. Acevedo on After she fell asleep at the wheel and crashed
a different path. “One night, I dreamt that Dr. her car in her apartment’s parking lot, she
José María Vargas, known as the Venezuelan knew she needed to make a change. “I decid-
father of medicine, was speaking on the tele- ed that if I wanted to cure my patients, I need-
vision, which was impossible as he had been ed to cure myself first,” Dr. Acevedo shared.
dead since 1854,” she recalled. “When I told
my mom, she said the dream meant that I It was her parents who suggested she consider
should be a doctor. switching to aesthetic medicine. “After my first
class, I fell in love with aesthetics,” she said. “I
“As we were speaking, the announcer on the have a deep passion for this beautiful specialty.”
radio congratulated all Venezuelan doctors be-
cause it was Dr. Vargas’ birthday,” Dr. Acevedo Practicing in Venezuela’s Paradise
continued. “My mom repeated, ‘You definitely In 2008, Dr. Acevedo moved to Margarita
have to be a doctor.’” Island, Venezuela, and started her aesthetic
practice. “I decided on this location because
Healing Through Aesthetics I was captivated by the vibe of the island and
Her mother was not the only one who believed its beautiful landscapes when I was a teen-
she should pursue medicine. “My dad saw that ager,” she admitted. “The air is clean, there
I liked brain teasers, chemistry and biology, and are no traffic jams, and it is multicultural – it is
thought that I would make a good doctor,” said Venezuela’s paradise!”
Dr. Acevedo. With her parents’ support, she ap-
plied and was accepted into medical school. Working on Margarita Island still has its chal-
lenges, according to Dr. Acevedo. “One of the
“I loved being a medical student,” she added. biggest challenges is lack of access to the
“But I soon learned that I hated being a doctor medical devices and technologies commonly
in the specialty I chose.” used abroad,” she explained. “My patients’
skin also reacts differently to many treatments
that are considered best practices in the U.S.
and Europe.”

These setbacks have required Dr. Acevedo to

combine her creativity with her knowledge of
aesthetics to achieve the results her patients
want. “It has been a rewarding challenge to
use my armamentarium and develop differ-
ent treatments that work for my patients,” she
mentioned.

Thriving in Practice and At Home

In 2011, Dr. Acevedo expanded her practice by
opening the largest aesthetic medical unit in
town with her physician husband, Hildemaro
Villasmil, MD, another aesthetic physician, and
two aestheticians – all of whom can run the of-
fice if she is giving lectures abroad or teaching.

When she is not working, Dr. Acevedo spends

time with her family, especially her six-year-old
Dr. Acevedo at the Eiffel Tower in Paris with her family daughter, Zoe Alexandra. “She wants to be an

88 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 my patients’ most common fears and deepest
dreams. In a way, I think it has been easier for
me to understand my female patients than it
might be for a man.”

When it comes to the specialty, Dr. Acevedo

believes the biggest challenge in the future
will be to remain authentic. “In a world of filters
and images created by artificial intelligence
(AI), it is vital to keep our patients looking like
themselves,” she said. “I find immense joy in
making my patients’ beauty my art form and
Dr. Acevedo and her daughter Zoe Alexandra having a using my expertise to enhance what makes
mommy-daughter day at a Princesses’ spa them unique.”

aesthetic doctor when she grows up, as well

as a pilot,” Dr. Acevedo shared. “I try to include
her in my work schedule and ask her to play
with me as much as I can. When she is not
with me or my husband, my mother watches
her, which is a big help.”

After 15 years of running her practice, traveling,

giving lectures and teaching, Dr. Acevedo has
learned that organization is key to maintaining
a healthy balance between her thriving career
and rich family life. “My husband and I divide
tasks and follow a schedule as much as pos-
sible. He is such a big fan of my job and will
cheer me on when I feel low,” she added.

A Female Perspective
While she is not an actor or singer, Dr. Acevedo
believes she is living out the life she envisioned
as a child. “I have had the opportunity to travel
with my family and visit beautiful places, which
Good to Know
was always important to me,” she said. “I have Fun Facts about
told people all over the world about myself, my Mariangel Acevedo, MD
story and what I love about aesthetics.”
Q. What is your favorite show?
Living this part of her dream is especially The Simpsons – I laugh before, during and after
meaningful for Dr. Acevedo when she thinks the joke!
of the women who raised her. “None of my
grandmothers had the opportunity to study Q. What is something unexpected about you?
or work, and my mom quit her job when I was I love rock and roll, and I am also a Yoga teacher.
very young,” explained Dr. Acevedo. “Every
Q. What is the most courageous thing you
time I am on stage, I feel that I honor them and have ever done?
all the women in my family that wanted to fol- Being a mom.
low their dreams but could not.”
Q. What is the first thing you do when you
While being a woman in a male dominated wake up?
field can be challenging, Dr. Acevedo sees Meditate.
the female perspective as a powerful asset.
Q. What brings you joy?
“I have not felt that being a woman has been
The smell of my daughter’s head and dad jokes.
a challenge,” she admitted. “I feel that being
a woman has helped me to be conscious of

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 89

Talent & Techniques Rediscovering Youth:Achieving a
Remarkable Facial Transformation
with Threads and Neurotoxin
By Francine Young, RN, MEP-C

Resulting from an unending quest by consum- patients with a comprehensive solution for
ers to turn back the hands of time and revive achieving a refreshed and revitalized lower
their youthful glow, the field of aesthetic medi- face without resorting to surgical interventions.
cine has witnessed remarkable innovations.
One such example – the combination of a Rachel’s Transformation:
full-face thread lift and injection of neurotoxin A Journey Towards Rejuvenation
into the lower face – has proven to be a game- Rachel came to my practice feeling self-con-
changer in rejuvenation, helping individuals re- scious about the skin laxity on her face. She
gain their lost confidence. was not ready for a facelift just yet and inquired
This treatment, powered by absorbable about nonsurgical options.
polydioxanone (PDO) threads, has evolved to
Pre-Care: The pre-care phase initiates the stra-
be one of the most flexible, durable and resilient
tegic groundwork for transformation, emphasiz-
techniques. In this edition of Talent & Techniques,
ing meticulous consideration of each patient’s
I will take a deep dive into the specifics of this
unique requirements.
transformative combination approach, from pre-
1. Comprehensive Consultation: During the
care to post-treatment, and explore how it has
consultation, Rachel expressed her con-
revolutionized outcomes for individuals like my
cerns regarding her facial skin laxity and its
patient Rachel, discussed in this editorial.
impact on self-esteem. A thorough facial as-
sessment provided insights into skin quality,
The Genesis of Rediscovering Youth extent of laxity, and texture, guiding a tai-
My journey to exploring nonsurgical, minimally lored approach.
invasive solutions to the signs of aging began 2. Personalized Treatment Plan: The heart of
with the core utilization of PDO threads. PDO the pre-care phase is the development of a
exhibits heightened resilience, offering a du- personalized treatment plan. It is not a one-
rable solution with results lasting from 12 to size-fits-all approach, but rather a highly cus-
18 months. The hydrophobic nature of PDO tomized roadmap for rejuvenation. For Rachel,
threads ensures a gradual breakdown through I recommended a powerful combination of the
hydrolysis over time, contributing to a sustained full-face thread lift and lower face neurotoxin.
and natural rejuvenation. Equally significant is Full Face Thread Lift: This component of
the biocompatibility of PDO threads, charac- the treatment was chosen to provide a
terized by their remarkable ability to integrate cheek pop, snatched jawline and restore
seamlessly with the body’s natural processes, youthful contours. I recommended the use
devoid of antigenic or pyrogenic reactions. of PDO threads as they are renowned for
their flexibility and durability.
Application of neurotoxins to the lower face Neurotoxins: Known for their ability to
represents a sophisticated approach to non- smooth and reduce the appearance of
invasive facial rejuvenation. By strategically in- wrinkles and fine lines, injecting neurotox-
jecting neurotoxins into key muscles, such as ins into the patient’s pull-down muscles –
the depressor anguli oris, mentalis, nerfertiti, depressor anguli oris, mentalis, nerfertiti,
platysma bands, accessory salivary glands and platysma bands, accessory salivary glands
cutaneous neck, the lower face experiences and cutaneous neck – enables the lower
a transformative lift. This precise intervention face to be elevated. Once the pull-down
allows for the elevation of pull-down muscles, muscles are released, it allows the zygo-
which fosters a balanced interplay with oppos- maticus major, zygomaticus minor, and
ing muscles. Consequently, the zygomaticus levator labii superioris to be elevated as
major, zygomaticus minor and levator labii su- they are no longer working against the
perioris are enabled to elevate, thus enhanc- pull-down muscles. In addition, using the
ing midfacial fullness. Furthermore, the release neurotoxin cutaneously can help the skin
of these pull-down muscles contributes to the look tighter and refreshed. The lower face
refinement of jawline contour, achieving a har- neurotoxin treatment aimed to provide a
monious and natural outcome. Beyond its aes- comprehensive solution to Rachel’s facial
thetic impact, this technique, as exemplified in concerns and enhance the overall results
studies, is proven safe and effective, providing of her transformation.

90 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

3. Informed Consent and Education: Preceding levels compared to nontreated sections. The in-
any procedure is the critical step of informed creased collagen production was maintained un-
consent. My patients, like Rachel, receive com- til the end of the study at seven months.1
prehensive technical information about pro-
posed treatments, fostering transparency and Synergizing with Neurotoxins
confidence as active participants in the journey. In the realm of ‘rediscovering youth’, one study
from Toxins on the mentalis muscle proves in-
Intra-Care: The treatment involved the strate- strumental. Classifying it into dome-shaped
gic placement of PDO threads under the skin, (Type A, 86.4%) and flat (Type B, 13.6%), the re-
creating a scaffold effect that lifts and tightens search informs tailored approaches based on
the sagging areas. Simultaneously, lower face morphology. This study also offers precision in
neurotoxin was administered to elevate her injecting botulinum toxin into the mentalis mus-
lower face, creating a snatched jawline. cle, identifying optimal locations: 5 mm to 10
mm from the midsagittal line and 20 mm to 30
Post-Treatment: The post-treatment phase un-
mm from a line connecting mouth corners.2 This
derscores the need for practitioners to contin-
anatomical insight, crucial in aesthetic proce-
ue to establish clear, realistic expectations with
dures, enhances our ability to pinpoint effective
the patient. This stage provides the opportu-
injection points and depths for targeted facial
nity for patients to understand achievable out-
rejuvenation. As we navigate patient journeys,
comes, with practitioners playing a pivotal role
incorporating this research seamlessly aligns
in expectation management. In Rachel’s case,
with our commitment to scientific precision in
meticulous pre-care preparation ensured she
the pursuit of ‘rediscovering youth’.
approached the chosen procedures with well-
defined expectations. Following the procedure, Facial soft tissue repositioning with neuro-
Rachel experienced ongoing improvements as toxins is a concept illuminated by Claudia
collagen production was stimulated, contribut- Hernandez, MD, and her team, who found
ing to a gradual and enduring enhancement in that neurotoxin injection is a safe and effec-
skin texture and elasticity. tive option for enhancing midfacial fullness
and jawline contour without the need for fill-
ers or surgical intervention.3

Conclusions: A Journey of Transformation

The combination of a full-face PDO thread lift
with lower face neurotoxin proves to be a dy-
namic duo for extended aesthetic benefits.
Neurotoxin used in the lower face plays a piv-
otal role by strategically limiting muscle move-
ment and creating an environment where the
effects of the thread lift are prolonged. The
reduced muscle activity ensures less stress on About
the threads, contributing to their longevity. the Author
Results from this technique have been consis-
tently promising. Facial soft tissues are reposi-
tioned, midfacial volume increases, lower facial
volume decreases and jawline contouring is
enhanced, all without any reported adverse
events. This approach has not only restored
confidence to individuals like my patient Rachel Francine Young, RN,
but also exemplified the possibilities of non-in- MEP-C
vasive aesthetic medicine. Ms. Young is an aesthetic
nurse dedicated to the
References: overall beauty, health and
1. Kim J, Zheng Z, Kim H, Nam KA, Chung KY. Investigation well-being of her patients.
on the Cutaneous Change Induced by Face-Lifting She provides cutting-edge
Monodirectional Barbed Polydioxanone Thread. aesthetic treatments that
Before and six weeks after a full-face thread lift with lower Dermatol Surg. 2017 Jan;43(1):74-80. doi: 10.1097/ yield spectacular, age-
face neurotoxins DSS.0000000000000925. PMID: 27748691. defying results – without
Photos courtesy of Francine Young, RN, MEP-C surgery. Her ambition as
2. Choi DY, Bae H, Bae JH, Kim HJ, Hu KS. Effective Locations
for Injecting Botulinum Toxin into the Mentalis Muscle; an aesthetic practitioner
Cadaveric and Ultrasonographic Study. Toxins. 2021 Jan has been recognized by
Clinical Data Support 27;13(2):96. doi: 10.3390/toxins13020096. PMID: 33514053; medical corporations and
The effectiveness of the PDO thread lift tech- PMCID: PMC7911364. physicians worldwide.
nique is further validated by clinical data. An ar- 3. Hernandez CA, Davidovic K, Avelar LET, Alfertshofer When she is not treating
ticle from Dermatologic Surgery provided valu- M, Freytag DL, Frank K, Moellhoff N, Bihun R, Green patients, she spends
JB, Cotofana S. Facial Soft Tissue Repositioning With her time traveling to
able insights into the impact of PDO threads on Neuromodulators: Lessons Learned From Facial educate and train medical
the skin. Changes in expression of collagen were Biomechanics. Aesthet Surg J. 2022 Sep 14;42(10):1163-1171. professionals across the
demonstrated after a thread lift, showing mean doi: 10.1093/asj/sjac090. PMID: 35416929. world.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 91

VIP Practice Spotlight Opulence Med Spa:
Pioneering Aesthetic Excellence
By Tawni Bosiljevac, Editorial Staff

The Aesthetic Guide (TAG) is excited to an- TAG: Dr. Brown, congratulations on being
nounce the new VIP Practice Spotlight Feature featured in the first-ever TAG VIP Practice
highlighting leaders and practices who are Spotlight. We understand you specialize in
helping to shape the future landscape of aes- minimally invasive cosmetic procedures.
thetic medicine. Results of their tireless quest So, what are the top five treatments in your
for excellence deserve to be shared — and practice in order of highest to lowest?
applauded — as advancements for the greater 1. Filler
benefit of our industry. We are quite thrilled to 2. Neurotoxin
start that applause! We appreciate all who use 3. Broadband light (BBL)
The Aesthetic Guide as a resource for new in- 4. Radiofrequency (RF) microneedling
formation, tips and updates, and invite anyone 5. Body contouring
who has a story to be shared to apply for the
VIP Practice Spotlight through the QR code at TAG: Do you see this changing over the
the bottom of the page. next five years, why?
Yes, I do. I believe that the dermal filler market
To kick off the first edition, we are featur- will continue to increase as more, and better,
ing Tara Brown, MD, an ophthalmologist at varieties become available.
Opulence Med Spa in La Jolla, Calif. She is
board certified by the American Board of TAG: Where do you see your practice as
Ophthalmology and specializes in neurotoxin having improved the most in the last five
injections, dermal fillers, microneedling, pro- years?
fessional plasma energy treatments, body Well, we focus on continually expanding our
contouring, medical grade chemical peels, treatment offerings to ensure we are up to
platelet-rich plasma (PRP) based facials and date on technology advances and staying
hair rejuvenation, facial capillary removal and competitive. We bring in a new device every
eyelid rejuvenation surgeries. year and we broaden our injectable offerings
whenever a new product meets our standards.

Practice Name:
TAG: What do you think makes your
Opulence Med Spa
practice unique?
I think it is our steadfast commitment to stay-
Location: ing current on technology and treatments to
La Jolla, CA ensure delivery of superior experiences and
Owner: outcomes to our patients. We evaluate new
Tara Brown, MD device and injectable technologies every
Years in Business: 17 year. If a new product meets our high stan-
dards, we train until we are the best provider
Number of Staff: 3 available on the market.
Annual Patient Volume:
1,200 total visits per year. TAG: How has your practice furthered the
80% are repeat patients. advancement of aesthetic medicine?
Practice Website:
I treat many breast cancer survivors. I spe-
www.tarabrownmd.com cialize in post-chemo facial rejuvenation and
post-mastectomy contouring with Sculptra
Understanding the special needs of mastectomy patients, Tara Brown, MD, has become a
(Galderma) and Nucleoskin (Promoitalia), which
specialist in post-chemo facial rejuvenation and post-mastectomy contouring. is another collagen boosting filler. The latter is
a specialty I have created based on my own
mastectomy experience. Restoring a smooth,
INTERESTED IN LEARNING MORE ABOUT natural breast contour after breast cancer treat-
ment is a real confidence booster and almost
HOW TO BECOME A TAG VIP PRACTICE? no one else offers it. I treat survivors for free
SUBMIT TODAY! during October and I do an annual fundraiser
Scan the QR code to get started for the Breast Cancer Research Foundation.

92 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 A SPECIAL PROGRAM TO
ADVANCE AESTHETIC MEDICINE AND BOOST CAREERS
The Medical Aesthetic Vanguard Program (MVP) provides
career-changing opportunities to physicians in practice one
to ten years who are making significant contributions to
aesthetic medicine.

The Medical Aesthetic Vanguard Program will:

Maximize Education
Increase Exposure
Provide Valuable Leadership and
Networking Opportunities

To qualify as an MVP, physicians must be in their first 10 years

of practice (proof required).

IF YOU KNOW AN MVP, HELP THEM REALIZE THEIR POTENTIAL

BY NOMINATING THEM TODAY!

tinyurl.com/AMWCAM-MVP
ADVALight AnteAGE MD
300 Enterprise Street, Suite G 1842 Barranca Pkwy
Escondido, CA 92029 Irvine, CA 92606
(888) 354-5551 (877) 350-6350
www.advalight.com www.AnteAGE.com
ADVATx is a solid-state, dual wavelength, 589 nm / 1319 nm laser AnteAGE MD® is pioneering the next generation of regenerative
with 16 FDA-cleared indications for everything from vascular aesthetics. Their Calif. based team of stem cell biologists has for-
and pigmented lesions, to scars, acne and wrinkle reduction. mulated products for both home and clinical use that leverage
The ADVATx laser provides versatility, clinical efficacy with no human growth factors, exosomes and peptides to accelerate
downtime for the patient, and a simple-to-use interface, without healing, minimize downtime and improve outcomes following
the need for consumables. laser, radiofrequency, microneedling and other treatments.

AGNES Medical BENEV Company, Inc.

2281 W. 190th Street, Suite 100 23263 Madero, Suite A
Torrance, CA 90504 Mission Viejo, CA 92691
(844) 811-1154 (949) 457-2222
us.agnesmedical.com www.BENEV.com
AGNES Medical is an aesthetic medical device manufacturer BENEV Company, Inc. is a U.S. FDA-registered pharmaceutical,
located in South Korea, formed with the vision of delivering clini- cosmeceutical and medical device company, that serves the
cally proven innovative technologies to aesthetic professionals global medical aesthetic market with scientifically advanced,
for dermatological conditions. Our flagship device, AGNES RF, innovative and result-driven regenerative, restorative and bio
is an unparalleled microneedling device utilizing engineered stimulatory products and devices.
radiofrequency energy and exclusive single and three-pin
needles for selective electrocoagulation of facial skin and focal
adiposities. Owned by a group of dermatologists who has the BTL Industries, Inc.
same goal as you. 362 Elm Street, Suite 5
Marlborough, MA 01752
(866) 285-1656
ALASTIN Skincare www.bodybybtl.com
3129 Tiger Run Court, Suite 109 Founded in 1993, BTL has grown to become one of the world’s
Carlsbad, CA 92010 major manufacturers of medical and aesthetic equipment. With
(844) 858-7546 over 1,900 employees located in more than 53 countries, BTL
www.alastin.com has revolutionized the way to offer the most advanced non-
ALASTIN Skincare® is a physician-dispensed skincare brand, invasive solutions for body shaping, skin tightening and other
with innovative, scientifically proven and clinically tested medical aesthetic treatments, including women’s intimate health
products. Founded in 2015, ALASTIN Skincare provides a and wellness. BTL’s brands include Emsculpt, Emsculpt Neo,
comprehensive collection of cutting-edge products for optimal Emsella, Emtone, Emface, Vanquish ME, Exilis ULTRA, Exion and
procedure results and daily skincare regimens. We strategi- Cellutone.
cally focus research and development on innovative products
with the greatest potential impact for patients and providers.
ALASTIN Skincare is thrilled to announce our new partnership Candela
with Galderma – a leader in the dermatological space. With a 251 Locke Drive
shared commitment to innovation and making a positive impact Marlborough, MA 01752
in the lives of our customers, this union is a match made in skin (508) 358-7400
heaven. Together, Galderma and ALASTIN will continue pro- www.candelamedical.com
viding breakthrough and high-quality products. For over 50 years, Candela has led the global energy-based
medical aesthetic device industry with a comprehensive product
portfolio based on science, results and trust. With a global dis-
Allergan Aesthetics, an Abbvie Company tribution footprint in over 100 countries and hundreds of patents
2525 Dupont Drive issued around the world, Candela strives to deliver the highest
Irvine, CA 92612 levels of efficacy, safety and reliability to our customers. We are
(714) 246-4500 dedicated to the development of innovative products that offer a
www.allergan.com broad range of treatment solutions, including laser hair removal,
We discover and develop innovative medicines for tomorrow, tattoo removal, scar and striae treatments and the reduction of
while helping people live better lives today. vascular and skin pigmentation.

94 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

Caregen Co., Ltd. Cutera
46-38, LS-ro 91beon-gil, Dongan-gu, Anyang-si 3240 Bayshore Blvd.
Gyeonggi-do, South Korea, 14119 Brisbane, CA 94005
+82-31-420-9200 (415) 657-5500
www.caregen.com www.cutera.com
Caregen is a global biotechnology company that has commer- Cutera is a leading provider of aesthetic and dermatology solu-
cialized the unlimited expandability of its patented peptides tions for practitioners worldwide. Since 1998, Cutera has been
as many innovative products. Over 600 different functional developing innovative, easy-to-use products that harness the
peptides developed by Caregen for 23 years have opened a power of science and nature to enable medical practitioners to
new paradigm in the field of biotechnology by expanding its offer safe and effective treatments to their patients.
applications to cosmeceutical, class III medical devices, food
supplements and pharmaceuticals.
DEKA M.E.L.A. s.r.l.
Via Baldanzese, 17
CAREstream America / Pro-Nox Calenzano, Firenze 50041 Italy
200 Technology Park, Suite 1040 +39 055 887 4942
Lake Mary, FL 32746 www.dekalaser.com
(855) 892-3872 DEKA designs, manufactures and markets medical lasers and
www.carestreamamerica.com/aesthetics pulsed light equipment for specialized medical requirements
CAREstream America offers cutting-edge aesthetic solutions in over 83 countries worldwide. Products include PHYSIQ, the
including the innovative Pro-Nox™, a 50/50 nitrous oxide/oxygen Motus AZ+ with MoveoGlo, Helix CO2 and 1570 nm platform,
analgesia system used to relieve procedure pain and anxiety SmartXide Tetra with Coolpeel, Motus AX and AY, Sculpt,
safely. Our CAREprpTM, body-jet® eco/evo for gentle waterjet- Onda and Red Touch, as well as other platforms for surgery,
assisted body contouring and lipofilling, and the VeinViewer for aesthetic medicine and dentistry utilizing a very wide range of
wavelengths such as CO2, Nd:YAG, Alexandrite, Er:YAG, Dye,
HD imaging are unparalleled. View our comprehensive portfolio
Q-switched, KTP lasers, Flash lamp and Excimer lamp systems.
at www.carestreamamerica.com.

Dp Derm
Congela Biocosmetics, LLC 11900 Biscayne Blvd, Suite 292
1728 Coral Way, Suite 600
North Miami, FL 33181
Miami, FL 33145
(305) 552-0550
(833) 436-8372
www.DpDerm.com
www.juvexo.com
Dp Derm LLC is the U.S. distributor for the DP4 microneedling
Congela Biocosmetics is a biocosmetic company that produces
device and Dp Dermaceuticals, the first protocol-based skincare
precision skincare that helps restore natural beauty at the cel-
line designed to improve and maintain the best possible results
lular level. As a leader in biological cosmetics, Congela has
when skin needling. Offering multiple customizable options
combined biological research with expertise in the aesthetic
for meso-infusion and combination therapies in-clinic, as well
industry to provide practitioners with optimal cosmetic solutions
as pre- and post-care at home. Including our latest exosome
to common skin and hair concerns.
products, Dp Dermaceuticals is designed to safely guide prac-
titioners and their clients along their journey to their best skin.
Crown Aesthetics
5005 Lyndon B. Johnson Freeway, Suite 370
Epionce
Dallas, TX 75244
10211 W. Emerald Street
(888) 372-3982
Boise, ID 83704
www.crownaesthetics.com
(866) EPIONCE (374-6623)
Crown Aesthetics, the premier medical aesthetics company, is www.epionce.com
dedicated to helping leading practices around the world grow
Epionce is a comprehensive and innovative set of products
their businesses by delivering dramatic results in rejuvenation
designed to optimize the appearance and health of the skin by
and restoration. Our minimally invasive innovations – BIOJUVE™,
first of its kind, living microbe technology for skin biome working at the core of the skin’s own protective and repara-
care; SkinPen®, the first FDA-cleared microneedling device; tive systems. Developed by a clinical dermatologist, the unique
MicroPen EVO™, platelet-rich plasma (PRP) systems; ProGen approach delivers a blend of active botanical ingredients to
PRP™ Advantage and Eclipse PRP®, VOTESSE™, a hair health deeply penetrate the skin. This helps to improve skin function,
system; and the post-microneedling protocol Skinfuse® – act as restore the natural protective barrier and reverse destructive
“gateway” products that drive new and highly satisfied patients skin inflammation. 15 independent clinical studies comparing
into practices. the marketed products against leading prescription products
have validated the technology of the Epionce line.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 95

Fotona Love Beauty Pro & Medical
2307 Springlake Road, Suite 518 800 W. Cummings Park, Suite 5950
Farmers Branch, TX 75234 Woburn, MA 01801
(972) 598-9000 (855) 568-3776
www.fotona.com www.lovebeautypro.com
Fotona develops and manufacturers high performance, quality Your B2B aesthetics partner. We are a team of innovators com-
made laser systems. Our wide range of laser systems survey mitted to helping our partner providers and practices succeed.
quality, reliability, safety and cutting edge innovation in treat- With our leading national sales team, distribution, and advanced
ment speed and efficiency. Our global network of representa- clinical training, we bring to you best-in-class aesthetic devices
tives and reference medical centers guarantee exceptional and products. Our top-tier support and training ensure maximum
customer support, as well as technical and clinical training. practice revenue and optimal patient outcomes. Our customers
include dermatologists, plastic surgeons, cosmetic physicians,
medical spas, NPs, PAs, nurses and aestheticians.
Galderma Laboratories, L.P.
14501 N. Freeway
Fort Worth, TX 76177 Lutronic Aesthetics
(817) 961-5000 19 Fortune Drive
www.galderma.com/us Billerica, MA 01821
(888) 588-7644
Galderma, the world’s largest independent global dermatology
www.Lutronic.com
company, has an extensive product portfolio of best-in-class
aesthetic solutions, prescription medicines and consumer Lutronic develops and manufactures products for quality, perfor-
care products. The company partners with aesthetic providers mance, durability and innovation. Every laser and radiofrequency
worldwide to impact the lives of patients by providing innovative device are intelligently designed with the practitioner and patient
solutions driven by ground-breaking medical research to help in mind. Lutronic is committed to bringing the most effective
patients achieve natural-looking results. energy-based devices to the marketplace to ensure exceptional
outcomes and improve the lives of everyone they touch.

GCC Aesthetics Inc. dba NassifMD Dermaceuticals

120 S. Spalding Drive, Suite 301 Martinni Beauty, Inc.
Beverly Hills, CA 90212 3035 Research Drive
(908) 963-7018 Richmond, CA 94806
www.nassifmdskincare.com (888) 440-8811
www.superfrecator.com
NassifMD Dermaceuticals® is formulated by board-certified www.martinnibeauty.com
facial plastic and reconstructive surgeon and star of Botched.
Dr. Nassif leverages his knowledge of the skin layers to develop Based in Calif., Martinni is a diversified multinational company.
luxurious yet affordable, science-based, cruelty-free skincare We take pride in making products across the globe with integrity
that delivers transformative anti-aging results for healthy, radiant, and passion. We started our operations in 2007, manufacturing,
youthful looking skin. No scalpel required! supplying and distributing wholesale beauty and skincare prod-
ucts. Embracing the Blue Zones way of living today, Martinni
has rediscovered the art of thoughtful and sustainable products
HIRONIC Co., Ltd. for estheticians, doctors, medspas, spas, destination resorts
19F U-Tower, 767, Sinsu-ro, Suji-gu, Yongin-si and hotels, and prestige retail. The Martinni brands and private
Gyeonggi-do, 16827 South Korea label services incorporate the beauty, wellness, and lifestyle
+82 31 525 7400 industry with premium devices and products in skincare, body
www.hironic.com care and more.
Under the slogan: ‘Happy maker’, HIRONIC leads the aesthetic
medical device industry as it develops itself beyond the Korean Med Results
local market into a global enterprise. Beginning the journey with 1111 N. Brand Blvd., Suite 350
the development of the HIFU Skin Lifting Device, HIRONIC has Glendale, CA 91202
expanded its lineup to reflect the leading trends in the aesthetic (310) 707-3223
medical device industry. www.med-results.com
With three decades of experience in the medical equipment
industry, we excel in providing innovative solutions you can rely
on, such as FDA-cleared Plexr Plasma and Act O’ Feel FHA. Our
cutting-edge technology and top-notch products empower you
to address previously untreatable indications, ensuring patient
satisfaction. From our comprehensive training programs to our
dedicated technical department and customer service, we are
committed to supporting you every step of the way.

96 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

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Merit Pharmaceutical PDO Max, Inc.
2611 N. San Fernando Road 4971 Bear Road, Suite 102
Los Angeles, CA 90065 Liverpool, NY 13088
(800) 69-MERIT / (800) 696-3748 (800) 670-0225
www.meritpharm.com www.pdomax.com
Is your practice offering IV Infusion treatments? Are you getting PDO Max threads are one of the few truly FDA cleared PDO
your medical, surgical, or pharmaceutical equipment from us? thread-in-cannula devices on the market. We offer a variety of
Merit supplies anti-aging, aesthetic and integrative practitioners sizes and types: Barbed, Smooth, Ciclone, Molded, Nose and
with better prices on the products you use. IV therapy nutrition more. Our focus is educating practitioners on minimally invasive
and hydration, weight loss, IV solutions, PRP products, exam, nonsurgical face and body lifting techniques through our exten-
surgical and more. Merit offers pharmaceuticals (2, 3, 3N, 4) and sive hands-on training workshops.
related medical products.

Powered by MRP
Merz Aesthetics 2720 Rasmussen Road, Suite A3
6501 Six Forks Road Park City, UT 84098
Raleigh, NC 27615 (435) 731-8232
(919) 582-8000 www.mrp.io
www.merzusa.com Started with the mission to create a market for physicians to
Merz North America, Inc. is a specialty healthcare company access energy-based devices at GPO-level pricing, Powered
dedicated to the development and marketing of innovative by MRP is the first online marketplace featuring new and pre-
quality products for physicians and patients across the U.S. and owned devices, consumables and supplies for all aesthetic
Canada. Merz products are distributed through two divi- needs. Users can buy, sell and trade-in their devices with trans-
sions, aesthetics and neurosciences, and developed with the parency, trust and velocity.
goal of improving patients’ health and quality of life.
QuantifiCare, Inc.
3325 Paddocks Pkwy.
MTF Biologics
Suwanee, GA 30024
125 May Street
(888) 678-4450
Edison, NJ 08837
www.quantificare.com
(732) 661-0202
(800) 946-9008 QuantifiCare has developed 3D imaging solutions for photog-
www.mtfbiologics.org raphy of the skin for 20 years. Building company’s early suc-
cess, QuantifiCare expanded to provide portable 3D LifeViz®
MTF Biologics Plastic Surgery & Aesthetics provides innovative,
systems to assist dermatologists, plastic surgeons and aesthetic
regenerative solutions to healthcare providers for patients world-
practitioners engendering greater patient’s understanding,
wide. This is accomplished through a dedication to advancing
reassurance and loyalty.
the science of regenerative medicine, delivering exceptional
service, providing meaningful education, supporting patient
advocacy, and honoring the gift of donated tissue to save, heal
and improve the lives of the patients we serve.
RATIONALE
8441 Melrose Pl.
Los Angeles, CA 90069
(424) 430-6698
PCA SKIN
www.RATIONALE.com
4110 N. Scottsdale Road, Suite 300
Scottsdale, AZ 85251 Since 1992, RATIONALE has been delivering luminous skin
(844) 722-2428 for life with the Essential Six, a customizable suite of formula-
www.pcaskin.com tions protecting daily through immune boosters, skin identical
antioxidants and innovative zinc oxide formulas combined with
For 30 years, PCA SKIN® has pioneered and perfected the
nightly skin repair through barrier restoration, pH recalibration
science of skin health. PCA SKIN continues to be a trusted
and unique retinoid/DNA repair enzyme technologies.
innovator in the development of highly effective professional
treatments and daily care products that offer individualized solu-
tions to deliver dramatic, visible results.

98 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

Joint meeting with

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SHEnB Co., Ltd. VIOLA Threads / AMA Meditime
655 North Berry Street, Suite A 315 N. Puente Street, Suite H
Brea, CA 92821 Brea, CA 92821
(888) 529-0994 (213) 351-0001
www.shenb.com www.violathreads.com
SHEnB is an aesthetic medical device manufacturer. Since VIOLA Threads provides medical aesthetic practitioners with
established in 1999, SHEnB has sought the opportunities for fully absorbable threads available in different shapes, sizes and
growth and innovation by continuously researching and devel- materials. Our polydioxanone (PDO) threads are U.S. FDA 510k
oping technologies specifically in the field of radiofrequency, Cleared (#K190264) for barbed suture and are indicated for use
ultrasound and plasma. Our representative medical devices in soft tissue approximation, where use of absorbable suture is
include VIVACE, VYBE RF, VirtueRF and PLADUO which have appropriate.
earned a reputation across the globe. VIVACE/VYBE RF and
VirtueRF are designed to maximize patient efficacy and com-
fort by applying outstanding microneedling technologies and Vivant Skin Care
reducing pain dramatically. 5757 NW 158 Street
Miami Lakes, FL 33014
(800) 984-8268
Sofwave www.vivantskincare.com
1211 Puerta Del Sol., Suite 200 Vivant is a medical grade line for the treatment of acne, hyper-
San Clemente, CA 92763 pigmentation and anti-aging. Vivant Skin Care was founded and
(855) Sofwave (763-9283) formulated in 1990 by James E. Fulton, MD, PhD, co-developer
www.sofwave.com of Retin-A and Benzoyl Peroxide gel (Panoxyl). Dr. Fulton also
Sofwave™ effectively utilizes synchronous ultrasound parallel introduced mandelic acid into the skincare industry.
beam (SUPERB™) technology, ensuring minimal downtime during
a single 30 to 45-minute session, regardless of skin type. FDA-
cleared and clinically validated, Sofwave remodels collagen and Vydence Medical
stimulates hyaluronic acid production, leading to enhancements 601 Brickell Key Drive, Suite 901
in facial lines, wrinkles, acne scarring appearance, cellulite and Miami, FL 33131
elevating the eyebrows, submental and neck regions. (303) 588-1602
www.vydence.com/us
Vydence is a global leader of laser platforms with offices in
Sylton, Inc. Miami, Fla. and São Paulo, Brazil. We manufacture and market
2327 South State Street, Suite 150 world class laser technology tailor-made to each provider’s
Ann Arbor, MI 48104 exact specifications. Vydence offers three platforms – ZYE Alex,
(734) 506-6052 Zye Yag and ETHEREA-MX – with exclusively featured hand-
www.sylton.com pieces such as the revolutionary handPICO, world’s first and
Sylton is the manufacturer of the Observ® Skin Analysis System. only fractional picosecond handpiece, and the ProDeep 1,340
Observ is the global standard for Skin Analysis delivering IOS nm non-ablative fractional Nd:YAP laser with a deep penetration
compatible HD images processed in just seconds. The system range. All of this ensures maximum return on investment and
is supported by an intuitive easy to use workflow app resulting superior patient outcomes.
in proper documentation of skin concerns and a treatment plan.
Observ facilitates compelling and convincing consultations that
will increase patient satisfaction and clinic profitability. ZianMed
1245 Rogers Street
Clearwater, FL 33756
Toskani US (727) 827-8090
2400 East Commercial Blvd. www.zianmed.com
Fort Lauderdale, FL 33309 Established in 2004, located in Fla., we are a premier aesthetics
(954) 804-8195 equipment provider, offering an array of laser, light and non-light
www.toskani.us based solutions. We provide comprehensive client training
ToskaniMed is a laboratory specialized in health and cosmetic and support, along with finance options and a monthly rental
products 100% designed for medical aesthetic treatments. We program.
provide medical professionals with the necessary products to
perform the most effective, efficient and safe treatments. Our
goal is to provide comprehensive and innovative solutions for
skincare professionals in the field of aesthetics. Our four pillars
are innovation, excellence, trust and dedication to service. With
more than 40 years of history, we are the past, present and future.

100 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 THE PREMIER MEDICAL MEETING FOR
MEDICAL AND COSMETIC DERMATOLOGISTS, PLASTIC SURGEONS, AESTHETIC
PROVIDERS AND PRACTICE ADMINISTRATORS.

SYMPOSIUM HIGHLIGHTS
» Full Day Facial Anatomy Course
» Full Day Devices 101 Workshop
» Hands on Workshop on Ultrasound in
» Aesthetics
» Exhibit Hall with over 150 Vendors
COURSE CO-DIRECTORS:
» Earn 25+ Hours of CME/CE Credit BRIAN S. BIESMAN, MD & MICHAEL H. GOLD, MD

L E A R N M O R E AT WWW.SCALEMUSICCITY.COM
Supplier Product(s) Key Component Description Physician Regulatory Status
Price
Allergan Aesthetics, CosmoDerm Purified Human-based Purified human-based collagen 35 mg/mL. $205 Worldwide
an AbbVie company
CosmoPlast Collagen + Lidocaine Purified human-based collagen 35 mg/mL, cross-linked with $235 Worldwide
glutaraldehyde.
*All collagen products contain 0.3% lidocaine.

HydraFill – Softline Non-animal Hyaluronic Acid Non-animal, cross-linked cohesive hyaluronic acid 24 mg/g. $200 – $225 CE marked.

HydraFill – Softline Max Non-animal Hyaluronic Acid + Non-animal, cross-linked cohesive hyaluronic acid 24 mg/g. $200 – $225 CE marked.
Lidocaine

Juvéderm ULTRA 2 Non-animal, cross-linked cohesive hyaluronic acid 24 mg/g. $200 – $225 CE marked.

Juvéderm ULTRA 3 Non-animal, cross-linked cohesive hyaluronic acid 24 mg/g. $200 – $225 CE marked.

Juvéderm ULTRA 4 Non-animal Hyaluronic Acid Non-animal, cross-linked cohesive hyaluronic acid 24 mg/g. $245 CE marked.
*All Juvéderm ULTRA products contain 0.3% lidocaine.

Juvéderm VOLUMA Non-animal Hyaluronic Acid Non-animal, cross-linked cohesive hyaluronic acid 20 mg/g. Contact mfr. CE marked for facial volume
restoration.

Juvéderm HYDRATE 13.5 mg/g plus mannitol 0.9%; 1 x 1 mL syringe. Contact mfr. CE marked.

JUVÉDERM VOLUX XC Hyaluronic acid Indicated for subcutaneous and/or supraperiosteal injection for Contact mfr. FDA approved 2022
improvement of jawline definition in adults over the age of 21
with moderate to severe loss of jawline definition.

JUVÉDERM VOLUMA XC Hyaluronic acid Indicated for deep (subcutaneous and/or supraperiosteal) Contact mfr. FDA approved 2020
injection for cheek augmentation to correct age-related volume
deficit in the mid-face and for augmentation of the chin region to
improve the chin profile in adults over the age of 21.

JUVÉDERM VOLLURE XC Hyaluronic acid Injectable gel indicated for injection into the mid to deep dermis Contact mfr. FDA approved 2017
for correction of moderate to severe facial wrinkles and folds
(such as nasolabial folds) in adults over the age of 21.

JUVÉDERM VOLBELLA XC Hyaluronic acid Injectable gel indicated for injection into the lips for lip Contact mfr. FDA approved 2022
augmentation and for correction of perioral rhytids, and for the
improvement of infraorbital hollowing in adults over the age of
21.
JUVÉDERM Ultra XC Hyaluronic acid Contact mfr. FDA approved 2010
Injectable gel indicated for injection into the mid to deep dermis
for correction of moderate to severe facial wrinkles and folds
(such as nasolabial folds), and for injection into the lips and
perioral area for lip augmentation in adults over the age of 21.
JUVÉDERM Ultra Plus XC Hyaluronic acid Contact mfr. FDA approved 2010
Injectable gel indicated for injection into the mid to deep dermis
for correction of moderate to severe facial wrinkles and folds
(such as nasolabial folds).

Galderma Restylane-L Hyaluronic acid manufactured Indicated for mid-to-deep injection into the facial tissue for the Contact mfr. FDA Approved in 2005.
Laboratories, L.P. using NASHA Technology* correction of moderate to severe facial wrinkles and folds, such P040024/S039
as nasolabial folds. Indicated for submucosal implantation for lip
augmentation in patients over the age of 21.

Restylane Lyft Hyaluronic acid manufactured Indicated for implantation into the deep dermis to superficial Contact mfr. FDA Approved in 2010
using NASHA Technology* subcutis for the correction of moderate to severe facial folds + 2015 for midface.
and wrinkles, such as nasolabial folds, and for subcutaneous P040024/S073
to supraperiosteal implantation for cheek augmentation and
correction of age-related midface contour deficiencies. Indicated
for injection into the subcutaneous plane in the dorsal hand to
correct volume deficit in patients over the age of 21.

Restylane Silk Hyaluronic acid manufactured Indicated for submucosal implantation for lip augmentation and Contact mfr. FDA Approved in 2005
using NASHA Technology* dermal implantation for correction of perioral rhytids in patients + 2014 for lip. P040024/S072
over the age of 21.

Restylane Contour Hyaluronic acid manufactured Indicated for use in cheek augmentation and correction of Contact mfr. FDA Approved in 2021.
using XpresHAn Technology** midface contour deficiencies in patients over the age of 21. P140029/S032

Restylane Defyne Hyaluronic acid manufactured Indicated for injection into the mid-to-deep dermis for correction Contact mfr. FDA Approved in 2016
using XpresHAn Technology** of moderate to severe, deep facial wrinkles and folds (such as + 2021 for chin indication.
nasolabial folds) in patients over the age of 21. Indicated for P140029/S027
injection into the mid-to deep dermis (subcutaneous and/or
supraperiosteal) for augmentation of the chin region to improve
the chin profile in patients with mild to moderate chin retrusion
over the age of 21.

Restylane Kysse Hyaluronic acid manufactured Indicated for injection into the lips for lip augmentation and the Contact mfr. FDA Approved in 2020.
using XpresHAn Technology** correction of upper perioral rhytids in patients over the age of 21. P140029/S021

Hyaluronic acid manufactured Indicated for injection into the mid-to-deep dermis for correction Contact mfr. FDA Approved in 2016. P140029
Restylane Refyne using XpresHAn Technology** of moderate to severe facial wrinkles and folds (such as
nasolabial folds) in patients over the age of 21.
FDA Approved in 2009.
injectable poly-L-lactic acid Indicated for correction of shallow to deep nasolabial fold Contact mfr. P030550
Sculptra contour deficiencies and other facial wrinkles for use in immune-
competent subjects. Intended for restoration and/or correction
*NASHA technology through which of the signs of facial fat loss (lipoatrophy) in people with human
stabilization is achieved by preserving
the naturally occurring hyaluronic acid
immunodeficiency virus.
network through minimal synthetic
crosslinks, products are differentiated by
the calibration size of the screen used to
extrude the gel to a defined size
**XpresHAn TechnologyTM (known as
Optimal Balance TechnologyTM [OBT]
outside the US), products are differentiated
by their degree of cross-linking and the
calibration size of the screen used to
extrude the gel to a defined size

Merz Aesthetics Belotero Balance – 22.5 mg/mL Hyaluronic Acid Sterile, bioresorbable, non-pyrogenic, viscoelastic, clear, Contact mfr. CE marked in Europe.
colorless, homogeneous gel device. Bacterially fermented, FDA approved.
injectable, hyaluronic-acid-based dermal filler.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

102 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

Supplier Product(s) Key Component Description Physician Regulatory Status
Price
Merz Aesthetics Radiesse CaHA Radiesse injectable implant is a sterile non-pyrogenic, semi-solid, Contact mfr. CE marked in Europe.
(Continued) cohesive implant, whose principle component is synthetic FDA approved.
calcium hydroxylapatite suspended in a gel carrier of sterile
water for injection, glycerin and sodium carboxymethyl cellulose
(1.5 cc, 0.8 cc).
Radiesse (+) CaHA RADIESSE (+) Lidocaine injectable implant is an opaque, sterile Contact mfr.
non-pyrogenic, semi-solid, cohesive implant, whose principle
component is synthetic calcium hydroxylapatite suspended in
a gel carrier of glycerin, sodium carboxymethyl cellulose 0.3%
lidociane hydrochloride and sterile water for injection (1.5 cc,
0.8 cc).
MTF Biologics Renuva Allograft Adipose Matrix Derived from allograft adipose extracellular matrix which Contact mfr. FDA Regulated 361 HCT/P
contains the same collagen, growth factors and proteins found in
native adipose tissue.

Prollenium Revanesse Lips+ HA concentration of 25 mg/mL Revanesse Lips+ is an FDA approved hyaluronic acid dermal Contact mfr. FDA approved.
filler that can be used for submucosal implantation for lip
augmentation in patients 22 years of age or older.
Revanesse Versa HA concentration of 25 mg/mL Revanesse Versa+ is an FDA approved hyaluronic acid dermal Contact mfr. FDA approved.
filler that can be used to treat moderate to severe facial wrinkles
and folds, including nasolabial folds in patients 22 years of age
or older.
Revance RHA Redensity Preserved Network Technology RHA Redensity is the first and only FDA-approved filler for Contact mfr. CE marked. FDA approved.
RHA 2 Non-animal Hyaluronic Acid injection into both the superficial dermis and dermis to treat
15mg/mL + Lidocaine 0.3% moderate to severe perioral rhytids. RHA Redensity has the
highest stretch score of the RHA Collection, and the highest
stretch of any hyaluronic acid filler in the U.S. Market.

RHA 3 Preserved Network Technology The RHA collection of fillers is for injection into the facial tissue Contact mfr. CE marked. FDA approved.
non-animal Hyaluronic Acid for the correction of dynamic facial lines, wrinkles and folds that
23mg/mL + Lidocaine 0.3% are moderate to severe, such as nasolabial folds.
RHA 4 Preserved Network Technology Indicated for injection into the mid-to-deep dermis for the Contact mfr. CE marked. FDA approved.
non-animal Hyaluronic Acid correction of moderate to severe dynamic facial wrinkles and
23mg/mL + Lidocaine 0.3% folds, such as nasolabial folds.
Preserved Network Technology Indicated for injection in the deep dermis to superficial Contact mfr. CE marked. FDA approved.
non-animal Hyaluronic Acid subcutaneous tissue for the correction of moderate to severe
23mg/mL + Lidocaine 0.3% dynamic facial wrinkles and folds, such as nasolabial folds.
Suneva Medical Bellafill Purified Bovine Collagen and 80% purified bovine collagen and 20% polymethyl- Contact mfr. FDA approved for the correction
PMMA methacrylate (PMMA) microspheres and 0.3% lidocaine. of nasolabial folds and moderate
to severe, atrophic, distensible
facial acne scars on the cheek in
patients over the age of 21 years.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

Manufacturer Product(s) Key Component Product and/or Mechanism of Physician Price Regulatory Status
Action Description
Allergan Aesthetics, BOTOX Cosmetic onabotulinumtoxinA 100 unit vial (2.5mL); 50 unit vial (1.25mL) – Contact mfr. FDA-approved treatment for the
an Abbvie Company Resulting dose/units per .1mL = 4 units temporary improvement in the
20 units glabellar lines appearance of moderate to severe
24 units (12 units per side) lateral canthal lines forehead lines, frown lines and lateral
20 units forehead lines canthal lines in adult patients.

Evolus JEUVEAU prabotulinumtoxinA-xvfs 100 Units, vacuum-dried powder in a single-dose Contact mfr. FDA approved for temporary
vial for reconstitution with 2.5 mL of preservative- improvement in the appearance of
free 0.9% Sodium Chloride Injection, USP, per 100 moderate to severe glabellar lines
Units. Treatment of glabellar lines: 0.1 mL (4 units) associated with corrugator and/or
by intramuscular injection into each of five sites, procerus muscle activity in adults.
for a total dose of 20 units.

Galderma Laboratories, L.P. Dysport abobotulinumtoxinA 300 Units of lyophilized powder in a single-use Contact mfr. FDA approved to treat frown lines
vial for reconstitution with 1.5 or 2.5 mL of between the brows.
preservative-free 0.9% Sodium Chloride injection.
It is indicated for the treatment of glabellar lines,
in which a total dose of 50 units, divided into five
equal aliquots of 10 units each, is administered
intramuscularly to each of the corrugator muscles
(2 injections in each) and the procerus muscle (1
injection) to achieve a clinical effect.
Approved to distribute in Europe
Alluzience abobotulinumtoxinA 0.625 mL (125 Speywood units) of Ready-to-use Contact mfr. (excluding Greece, Lithuania, Estonia,
BoNT-A liquid neuromodulator formulation Latvia, Hungary).

Merz Aesthetics Xeomin incobotulinumtoxinA (150 kDa) Botulinum toxin type A produced from Contact mfr. FDA approved for temporary
fermentation of Hall strain Clostridium botulinum improvement in the appearance of
serotype A; purified from the culture supernatant; moderate to severe glabellar lines
the active ingredient is isolated and separated associated with corrugator and/
from the proteins, using two-step chromatography, or procerus muscle activity in adult
yielding the active neurotoxin without complexing patients.
proteins. Stabilized with the well-known excipients
HSA and sucrose. 50 units or 100 units lyophilized
powder in a single-dose vial for reconstitution
only with preservative-free 0.9% Sodium Chloride
injection, USP.

Revance DAXI DaxibotulinumtoxinA 150kD Botulinum Toxin Type A Contact mfr. Currently under regulatory review for
treatment of glabellar lines, forehead
lines and lateral canthal lines;
approval expected 2022.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 103

 Collagen Stimulation

Post-Procedure Tx

Wrinkle Reduction
Pre-Procedure Tx

Skin Lightening
Scar Reduction

Sun Protection
Exfoliation
Acne Tx

Firming

Peel
Manufacturer / Supplier Website

AnteAGE MD • • • • • www.anteage.com

Dp Derm • • • • • • • • • • www.DpDerm.com

ELEVAI Labs • • • • • • www.elevaiskincare.com

Epionce • • • • • • • • • www.epionce.com

NassifMD Dermaceuticals • • • • • • www.nassifmdskincare.com

PDO Max PDO AfterGlo • • • • • • www.pdomax.com

PRX Derm Perfexion (WiQo) • • • • • www.lovebeautypro.com/PRX

( plated ) Skin Science • • • www.rionaesthetics.com

Smart Solutions RX, Inc. / LOCKrx Hair Support • • www.smartsolutionsrx.com

SkinCeuticals, LLC • • • • • • • • www.skinceuticals.com

SkinMedica, an Allergan Company • • • • • • • • • • www.skinmedica.com

WiQo • • • • • www.lovebeautypro.com/PRX

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

104 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

Manufacturer Product(s) Device Type Description Physician Price Regulatory Status

BENEV Company, Inc. Miracu PDO Threads Elasty Meshfill, Elasty Line, Forte Basic, Forte Fix, Contact mfr. FDA cleared for soft tissue
Barb FC and FCN, Elasty Meso Needle, Elasty approximation where use of an
Micro Cannula. absorbable suture is appropriate.
(K172602)

Miracu Elasty Meshfill Pre-loaded cannula 16-line mesh thread $520/box (10 units) FDA Cleared Class II (K172602)

Miracu Elasty Line Pre-loaded cannula Cone anchor thread with double coating and press $520/box (10 units) FDA Cleared Class II (K172602)
sculpting

Miracu Forte Basic Pre-loaded cannula Forte Basic thread has strong fixation with deep $420/box (10 units) FDA Cleared Class II (K172602)
bi-directional cogs. Forte 2 thread has strong
fixation with inverted deep bi-directional cogs.

Miracu Forte Fix Pre-loaded cannula Provides superior traction power and holding $440/box (10 units) FDA Cleared Class II (K172602)
through enhanced dual action technology and
4-dimensional multi bi-directional blocking
technology with heatless press sculpting.

BIONICA Company VICTORIA Thread Cosmetic threads for soft tissue VICTORIA Thread Sutures represent a collection Contact mfr. CE marked. FDA cleared.
Sutures approximation. of PDO threads including linear mono and
smooth, barbed, embossed linear and smooth,
volumizing, threads with two needles. Durable
and long-lasting polymer. Uses raw materials and
follow vacuum drying process to receive a final
product with optimal concentration of water.

BS Medical Resculpt Medical PDO Threads Offer a wide variety of PDO threads including an Contact mfr. FDA 510K Cleared
Threads exclusive line of threads pre-loaded on correction
enabled cannulas that allow the ability to retract
and replace so that the thread can be placed
precisely and decrease risk of complications due
to misplacement. Offered exclusively are BOOST
braided threads that are thick to promote robust
collagen production and can be used as an
alternative to filler. Other threads for all different
skin types, conditions and skill levels are offered
and purchases include training and support.

HansBiomed USA, Inc. MINT FINE+ Bi-directional PDO Thread MINT FINE+ is the quintessential PDO thread. Contact mfr. FDA Cleared
It is a powerful 18 cm long bi-directional thread
pre-cannulated in a 18G W type cannula. It has
high tensile strength, remarkable versatility, and
exceptional ease of use, making it the ideal tool
for your thread lifting needs.

MINT PETIT+ Bi-directional PDO Thread MINT PETIT+ offers the benefits of FINE+ in a more Contact mfr. FDA Cleared
compact way. It is designed with 2 cm of barbs of
lifting and 4.5 cm of barbs for anchoring. The high
distribution of bi-directional barbs across a shorter
thread length makes this revolutionary thread
the perfect choice for reverse vector designs and
micro-contouring.
Contact mfr. FDA Cleared
MINT 17+ Bi-directional PDO Thread MINT 17+ offers the signature MINT lift and
anchorage in a pre-loaded cannula. The bullet
tip makes it easy to pass the cannula through
resistant tissue. The stabilizer cap prevents the
thread from prematurely latching onto the tissue to
allow the user better control of when and where to
engage the thread.

Meditime Co., Ltd. VIOLA Threads PDO Threads Fully biodegradable threads available in different Contact mfr. U.S. FDA (510k) Clearance
shapes, sizes and materials, including 5D Fix
Coglyft and Doublelyft Flat Mesh. U.S. FDA
(#K190264) cleared for barbed sutures, PDO
threads are suitable for soft tissue approximation
and are ideal for non-invasive procedures like
full-face and body contouring, skin tightening, scar
improvement and promoting neocollagenesis.

PDO Max, Inc. Levo Lock Molded barbed/cog PDO thread Bi-directional anchoring thread, U.S.P. size 1. Best Contact mfr. FDA cleared for thread-inside-cannula
used for advanced reverse vector techniques (full device) (K190245)

Levos Omni-directional barbed/cog Strongest tensile strength threads on the market: Contact mfr. FDA cleared for thread-inside-cannula
PDO thread 18G is U.S.P. size 2; 19G is U.S.P. size 1, 21G is (full device) (K190245)
U.S.P. size 0

Multi-Smooth Multi-threads Seven smooth threads inside one cannula. Great Contact mfr. FDA cleared for thread-inside-cannula
PDO Thread for filling and plumping the skin around the cheek, (full device) (K190245)
nasolabial folds and temporal hollows and treating
deep lines like "11s".

Suneva Medical Silhouette Instalift Absorbable suture/thread with Composed of Poly lactic-co-glycolic acid (PLGA). Contact mfr. FDA cleared in 2015.
bi-directional micro cones First cleared absorbable suture with patented
bi-directional micro cones to provide both an
immediate lift and long-term lift. Silhouette
Instalift sutures and cones are composed of 18%
PLGA and 82% PLLA.

V Soft Lift USA VSoft Lift PDO Threads PDO Threads Committed to extensive research and Starting at $5/thread FDA cleared Class II
development to deliver a strong lift and some
of the best collagen and elastin biostimulation
available. Offer a wide variety of different types
and sizes of PDO threads to meet many individual
patient needs. Offers extensive and innovative
high-end PDO thread portfolios.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 105

Supplier Device Wavelength (nm) Energy Pulse Price Accessories
Product Name Type Output (Joules) Length
AMA Meditime
Oligio Monopolar RF N/A Up to 400 W N/A Contact mfr. Functions using two tip types for full face or periorbital
eyelid areas (body tip in development). Other cost-
efficient consumables required are Oligio Coupling
Fluid, Grounding Pads, and Cryogen Gas canisters.
BENEV Company, Inc.
Sylfirm X Emerging Dual Wave RF N/A N/A Pulse Wave Mode: MSRP Sylfirm X Standard and XE Tip
Microneedling System 30 msec - 60 msec; $149,000
Continuous Wave Mode:
120 msec - 300 msec

SmartLux Mini SLD Phototherapy Blue (415 - 425 nm), Red 75 W/cm3 ~ 90 W/cm3 N/A MSRP $13,000 N/A
Device (630 – 640 nm), Infrared
(820 – 830 nm)
Cutera
xeo Laser 1064 nm Up to 300 J/cm2 Up to 300 ms Contact mfr. Optional IPL handpieces. Laser Genesis.

excel V+ Laser 532 nm, 1064 nm Up to 300 J/cm2 Up to 60 ms Contact mfr. 1 mm and 2 mm Dermastat pens. Laser Genesis and
Green Genesis.

enlighten (Pico Genesis) Laser 532 nm / 670 nm / 1064 nm 400 mJ / 125 mJ / 750 ps, 2 ns / 660 ps / Contact mfr. No per treatment consumables. All accessories
800 mJ 750 ps, 2 ns included.

Secret PRO Fractional CO2 / Bipolar 10,600 nm / 2 MHz Up to 30 W (up to 175 20 – 5,000 μs / Contact mfr. Surgical CO2 handpiece available. RF Microneedling tips
RF Microneedling mJ) / 70 W (64 pin), 50 – 950 ms are gold-plated for biocompatibility, semi-insulated and
25 W (25 pin) non-insulated, 0.25 mm thin, and available in 25 or 64
pin arrangements.

Secret DUO Laser + Bipolar RF 1540 nm / 2 MHz Up to 12W / 70 W 700 - 5000 μs / Contact mfr. 1540 nm handpiece available with 300 and 600
Microneedling (64pin), 25 W (25 pin) 50 – 950 ms μm tips. RF microneedling tips are gold-plated for
biocompatibility, semi-insulated and non-insulated, 0.25
mm thin, and available in 25 or 64 pin arrangements.

DEKA
SmartXide DOT Fractional CO2 0.6 μm 50 W max 200 – 2000 μs Contact mfr. DOT Scanner and Free hand handpiece; touch screen
monitor, Stack feature, Smart Track delivery mode,
Smart Pulse, patient database, CW, PW, traditonal and
fractional scanning modes available.

SmartXide2 Fractional CO2 10.6 μm 80 W max 100 – 2000 μs Contact mfr. PSD technology with selectable pulse shape (SP, DP,
UP; HP, PW, CW, traditional and fractional scanning
modes available), DOT/RF scanner with RF feature, Free
hand, TFT touch screen monitor, Stack and Smart Track
delivery mode, multimedia built-in training videos, huge
patient database with videos and photos. User protocol
storage. Optional diode laser module.

SmartXide Touch Fractional CO2 10.6 μm 60 W max 100 – 2000 μs Contact mfr. PSD technology with selectable pulse shape (SP, DP, HP,
PW, CW, traditional and fractional scanning modes
available), DOT/RF scanner with RF feature, Free hand,
TFT touch screen monitor, Stack and Smart Track
delivery mode, multimedia built-in training videos, huge
patient database with videos and photos. User protocol
storage. Optional diode laser module. Multidisciplinary.

SmartXide Tetra Fractional CO2 10.6 μm 50 W max 100 – 2000 μs Contact mfr. PSD technology with selectable pulse shape (SP,
DP, HP, PW, CW, traditional and fractional scanning
modes available), DOT/RF scanner, Free hand, TFT
touch screen monitor, Stack and Smart Track delivery
mode, huge patient database. User protocol storage.
Multidisciplinary.

MiniSilk FT Pulsed Light System 500 nm, 520 nm, 550 nm; 2 – 2.5 J/cm2 2 – 85 ms (1-3 pulses) Contact mfr. Interchangeable snap-on filters; integrated skin contact
600 nm; 650 nm Filter cooling; lamp water cooling; transportable. 3.1 cm2 or
6.2 cm2 spot area available. IR filter available for
increased skin tightening.

Synchro FT Multifunctional Platform 1064 nm Nd:YAG / IPL: 500 700 J/cm2 (max) SP From 0.8 – 10 ms SP; Contact mfr. Five application-specific handpieces. Top hat technology
nm, 520 nm, 550 nm; 600 and LP / 160 J (max) from 2 – 30 ms LP (1-3 and Auto Spot Size Recognition System; contact cooling
nm; 650 nm energy per pulse pulses) / From 3 – 8 ms or optional external cooling connections; delivery pulse
settings available; patient database and protocols.
IPL: five optional filters, 30,000 shots guaranteed. No
disposables.

Synchro REPLA:Y Multifunctional Platform 755 nm Alexandrite / 1064 63.5 J (max) – 125 W From 2 – 50 ms (single Contact mfr. Alex emission: 5 Hz and high power (125 W) system.
nm Nd:YAG / IPL: 500 nm; (max) / LP: 120 J – pulse); from 2 – 40 ms Nd:YAG laser module: 180 W with up to 27,000 W
520 nm; 550 nm; 600 nm; 180 W (max); SP: 120 (double pulse) / From 2 – pulse peak power; three delivery pulse designs and
650 nm J (max) / 160 J (max) 50 ms SP mode; from 0.2 adjustment feature for Alexandrite and Nd:YAG. Twelve
energy per pulse – 12 ms LP mode / From application handpieces up to 24 mm. Auto Spot Size
3 – 8 ms Recognition System. Top hat technology; contact
cooling or optional external cooling connections; patient
database and protocols; IPL: five filters (optional) with
enhanced vascular capabilities; 500 G. No disposables.
LUXEA Multifunctional Platform Lilac, 6.2 cm2 Single Pulse: Contact mfr. Flexible multifunctional platform; several handpieces
Prisma, interchangeable from 3 – 50 ms, 6 ns, with integrated peltier skin contact cooling. Different
Sparks, filters: 550 nm, 6 – 30 ms, 8 ms, 30 ms, filter solutions for different skin rejuvenation needs
Lazur, 600 nm and 650 – 50 ms, from 5-50 ms. (either vascular; BPL, etc..) Up to 10 Hz rep rate
Viridis 1200 nm. 1064 nm available on laser wavelengths. Additional standard
Q-switched: 2x2 mm/ handpiece for vascular, skin rejuvenation and other
3x3 mm spot size. dermatology indications. Contact cooling and
1064 nm Nd:YAG: delivery pulse settings available. Three filters with
2.5 mm/4 mm/6 mm/ up to 120,000 shots guaranteed IPL included. No
10 mm spot size. disposables.
6.2 cm2 integrated
420 – 1200 nm filter.
2.1 cm2 integrated
500 – 677 nm and
854 – 1200 nm
(band pass) filter
called 500 G.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

106 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

Supplier Device Wavelength (nm) Energy Pulse Price Accessories
Product Name Type Output (Joules) Length
DEKA (Continued)
Motus AY High Frequency 755 nm / 1064 nm Up to 30 J / up to From 2 – 50 ms (single Contact mfr. Transportable device, integrated Peltier skin contact
Alexandrite / Nd:YAG 60 J pulse); from 4 – 80 ms cooling. Up to 20 mm spot area with up to 10 Hz rep. rate
Laser (Twin pulse) / From 2 – 50 on both Nd:YAG and Alex wavelengths. Proprietary new
ms SP mode; from 0.2 – Mòvèo technology functionality for painless and smokless
12 ms LP mode hair removal. Additional standard handpiece for vascular,
skin rejuvenation and other dermatology indications.
Motus AZ+ High Power and 755 nm Alexandrite; 1064 Up to 31 J (62W); Single mode pulse length Contact mfr. Transportable device, integrated Peltier skin contact
Frequency Alexandrite & nm Nd:YAG Up to 63 J (94W) 2 – 50 ms, Burst Pulse cooling; hair removal, pigmented and vascular lesion
Nd:YAG Laser length 4 – 80 ms, Total treatments applied through either proprietary new
burst length 14 – 300 ms; Mòvèo Technology functionality for total painless and
1 – 10 Hz rep. rate. smokeless handpieces or standard up to 20 mm spot
size optional handpieces. Up to 10 Hz rep. rate on
both Nd:YAG and Alexandrite wavelengths. 180° wide
touch screen, adjustable display for optimal view during
sessions, high power 1200 micron fiber connectivity and
automatic handpiece recognition with no need to turn
machine off.
HELIX Fractional CO2 / 1570 nm 10.6 μm / 157 nm 70 W max 10600 nm: 0.4 ms - 4 ms Contact mfr. Two wavelengths sequentially used with different
1570 nm: 0.4 ms - 12 ms patterns. PSD technology with selectable pulse shape
(SP-DP-HP-PW-CW, traditional & fractional scanning
modes available), DOT/RF scanner, free hand, TFT touch
screen monitor, Stack and Smart track delivery mode.
Storing user's protocols. Multidisciplinary.

Fotona
SP Dynamis Nd:YAG / Er:YAG 1064 nm / 2940 nm Up to 600 J/cm2 0.1 – 50 ms Contact mfr. F-Runner, fractional Er:YAG scanner: 250 μm spot size,
168 mm2 Tx area S-Runner, Er:YAG scanner: 4 mm spot
size, 16 cm2 Tx area. S-11: Nd:YAG scanner: 42 cm2 Tx
area. Er:YAG handpieces: 0.25 – 12 mm spot sizes;
Nd:YAG handpieces: 2 – 20 mm spot sizes.
XS Dynamis Er:YAG 2940 nm Up to 500 J/cm2 0.1 – 1.5 ms Contact mfr. F-Runner, fractional Er:YAG scanner: 250 μm spot size,
168 mm2 Tx area S-Runner, Er:YAG scanner: 4 mm spot
size, 16 cm2 Tx area. Er:YAG handpieces: 0.25 – 12 mm
spot sizes.
XP MAX Nd:YAG 1064 nm Up to 600 J/cm2 0.1 – 300 ms Contact mfr. S-11: Nd:YAG scanner: 42 cm2 Tx area. Nd:YAG
handpieces: 2 – 20 mm spot sizes.
QX MAX Nd:YAG Q-Switched / 1064 nm, 532 nm, 585 nm, Up to 160 J/cm2 5 – 20 ns / 250 μs Contact mfr. Handpieces: 2 - 8 mm spot sizes.
Long Pulse 650 nm

SP Spectro Nd:YAG / Er:YAG 1064 nm / 2940 nm Up to 600 J/cm2 N/A Contact mfr. F-Runner fractional Er:YAG scanner: 250 μm spot size,
168 mm2 Tx area. S-Runner Er:YAG scanner: 4 mm spot
size, 16 cm2 Tx area. S-11 Nd:YAG scanner: 42 cm2 Tx
area. Er:YAG handpieces: 0.25 – 12 mm spot sizes;
Nd:YAG handpieces: 2 – 20 mm spot sizes.
XP Spectro Nd:YAG / Long Pulse 1064 nm Up to 600 J/cm2 0.1 – 50 ms Contact mfr. S-11 Nd:YAG scanner: 42 cm2 Tx area. Nd:YAG
handpieces: 2 – 20 mm spot sizes.
XP Dynamis Nd:YAG / Long Pulse 1064 nm Up to 600 J/cm2 0.1 – 50 ms Contact mfr. Same as above.

StarWalker MaQX Nd:YAG Q-Switch Pico / 523 nm, 585 nm, 650 nm, Up to 300 J/cm2 580 ps, 0.6 – 50 ms, Contact mfr. R28, R29, R58, R585, R650, FS20, FS20A, FS20B,
Nano 1064 nm 5 ns / Hybrid Pico in FS50, up to 20 mm spot size.
Nano, Fractional
TimeWalker Nd:YAG / Er:YAG 1064 nm / 2940 nm Up to 600 J/cm2 0.6 ms – 60 sec Contact mfr. R33T, PSO3X, LA adapter, R30Y and R11.

HIRONIC Co., Ltd.

NEW DOUBLO MFU / RF / combined N/A Face max. 1.5 J; Body N/A Contact mfr. Handpieces (SD, FL), Footswitch
function with MFU max. 3.0 J
and RF

DOUBLO GOLD HIFU N/A Max. 2.0 J N/A Contact mfr. Four types of cartridges: max. 22,000 shots.

GENTLO RF Microneedle N/A Level 1 ~ 10 N/A Contact mfr. Plasma handpiece, vaginal applicator, acne applicator.

PICOHI Nd:YAG Laser 1064 nm / 532 nm Max. 500 mJ / max. 300 ps Contact mfr. Six types of handpieces.
250 mJ
SILKRO RF microneedling N/A Level 1~10 N/A Contact mfr. Four handpieces (RM, RN, RC, RV)

Lutronic Aesthetics
DermaV Nd:YAG laser 1064 / 532 nm Up to 600 J/cm2 0.1 - 300 ms Contact mfr. Digitally-based Nd:YAG platform that includes cryogen
cooling with 532 nm and exclusive multi-pulse
applications to effectively treat all vascular and
pigmented lesions. Standard spots of 2 - 16 mm are
included with single fiber, advanced handpiece,
IntelliTrak and Temperature Sensing.

eC02 Plus CO2 Fractional Laser 10600 nm Up to 240 mJ 40 - 1,000 us; 1-5 ms Contact mfr. Customizable fractional CO2 treatments with advanced
capabilties to safely deliver laser resurfacing to lighten
and brighten patient complexions, including the
reduced appearance of acne scars.

Genius Bipolar Fractional RF N/A 50W 10 - 1,000 ms Contact mfr. N/A

Microneedling
Hollywood Spectra Nd:YAG Nano-Acoustic 1064 / 532 nm Up to 1.4 J 5 ns and 0.3 ms Contact mfr. Proven short-pulse platform for reducing unwanted
Laser Optional Dye HPs: pigment and stimulating collagen with low downtime.
585 / 650 nm HyperSurge, IntelliBeam and MDF Microbeam
technologies included as standard for complete
lightening and brightening treatment benefits.
Exclusive Hollywood Laser Peel and AcnePeel
treatments.
Ultra Thulium Laser 1927 nm 1 - 20 mJ at 20 W N/A Contact mfr. Highest powered non-ablative fractional thulium laser
is fully customizable to all patient skin types, year
round. Reduces pigment and stimulates collagen
with minimal patient downtime. Optional serums and
cooling masks can complement the experience and
allow for new treatment capabilities.

Sofwave
Sofwave Ultrasound N/A 60 - 70 degrees, 1.5 N/A Contact mfr. Handpiece
mm depth, 7 parallel
ultrasound beams

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 107

 Supplier Product Technology Applications Price

AGNES Medical AGNES Monopolar square wave RF microneedling Partially insulated single or three-pin needles; ranging between 0.8 Contact mfr.
mm - 5.0 mm, depending on which needle is being utilized and the
target depth. Rounded cannula needle electrode, 40.0 mm length
with five different types, 18 - 23 G. Precision RF for nonsurgical
facial sculpting, skin laxity and focal adiposity.

Air-Tite Aesthetics CuraCator Sterile topical product applicator New standard of care for hands-free, needle-free, controlled $240 per
application of products such as PRP and exosomes to skin or other box of 20
tissue. Recommended for use with Luer Lock Syringes. applicators

BENEV Company, Inc. Sylfirm X Pulsed Wave and Continuous Wave RF microneedling Pulsed Wave mode for skin complexion treatment creates a MSRP
device with 300 micron depth. soft coagulation selectively in the basal layer and upper dermis. $149,000
Continuous Wave mode for skin revitalization creates wide,
independent coagulation around each electrode. 300 Micro
Depth for optimal skin revitalizing depth is the only treatment that
has the capability of treating epidermis, basement membrane
and papillary dermis skin layer at the same time. Non insulated
electrodes give minimal downtime with no noticeable thermal
damage found in epidermis.

Candela Profound Bipolar RF Microneedling Jawline, submental area, wrinkles and cellulite. Contact mfr.

Profound Matrix, Matrix Pro Short-Pulse RF Microneedling Dermatologic and general surgical procedures for Contact mfr.
Applicator electrocoagulation and hemostasis

Exceed Microneedling Facial wrinkles and acne scar reduction Contact mfr.

CosmoFrance, Inc. CosmoPen Bundle Microneedling Acne, surgical scars (including keloids), wrinkles, stretch marks, Contact mfr.
pore size, hair growth and signs of aging.

Crown Aesthetics Eclipse MicroPen Elite Microneedling Improved appearance of fine lines, scars and texture. Contact mfr.

Eclipse MicroPen EVO Microneeding; 14 32G stainless steel needles; 7000 Wrinkles of the neck and facial acne scars for patients aged 22 and Contact mfr.
RPM (+/-10%); fluid-resistant turbo safety cartridge; up. Clinically demonstrated, FDA-cleared microneedling device.
Teflon gear seal

SkinPen Precision Mechanical Microneedling; FDA-Cleared; Single-Use Wrinkles of the neck and facial acne scars for patients aged 22 Contact mfr.
Cartridge Unit; 14 32-Gauge Needles; Ergonomic and up. Clinically demonstrated, FDA-cleared microneedling
Design; Cordless All-Day Charge device.

Cutera Secret RF Bipolar RF Microneedling Address the signs of aging, scars, large pores, stretch marks, skin Contact mfr.
quality, appearance, brightness and texture through coagulation
and hemostasis using gold-plated, semi-insulated and non-
insulated microneedles in 25- or 64-pin arrangements.

Secret PRO Fractional CO2 / Bipolar RF Microneedling Fractional CO2 laser technology for optimal skin resurfacing. RF Contact mfr.
microneedling for deep dermal remodeling through hemostasis
and coagulation to effectively treat the full thickness of the skin.

Secret DUO N/A RF microneedling with precise, controlled radiofrequency energy Contact mfr.
at adjustable depths to target common skin concerns on the
face and body. 1540 nm wavelength offers a gentler approach
to skin resurfacing, delivering dermal thermal heating in multiple
micro-columns without any damage to the skin surface, patients of
all skin types can safely achieve meaningful improvement in their
skin concerns with little to no downtime.

HIRONIC Co., Ltd. SILKRO RF microneedling Skin rejuvenation, collagen remodeling, acne scars and wrinkles Contact mfr.
treatment.

MRP Intracel PRO RF Microneedling Monopolar/Bipolar RF Microneedle Skin rejuvenation and tightening Contact mfr.

Refine USA, LLC Rejuvapen NXT Microneedling FDA cleared for fine lines and wrinkles. $2,995

SHEnB Co., Ltd. VirtueRF Four key technologies: Advanced cooling system N/A Contact mfr.
(ACS), integrated pulsed radiofrequency system
(IPRS), integrated energy control system (IECS) and
minimum depth control system with three types of
handpieces (Smart RF, Deep RF and Exact RF) in one
platform.

Contact mfr.
Versatile treatment options of radiofrequency energy N/A
VIVACE (VYBE RF) output (1MHz, 2MHz) with 36 gold-coated needles TIP
and two different LED modes during treatment.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

108 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

Supplier Device Wavelength (nm) Energy Pulse Price Accessories
Product Name Type Output (Joules) Length

Cutera
xeo pearl YSGG 2940 nm Up to 3.5 J/cm2 ≤1000 μs Contact mfr. No per treatment consumables. All accessories included

xeo pearl fractional YSGG 2940 nm <400 mJ ≤1000 μs Contact mfr. No per treatment consumables. All accessories included

Secret RF RF Microneedling RF: 2 MHz 70 W (64 pin), 25 50 – 950 ms Contact mfr. Gold-plated, 0.25 mm thin needles (33G) in 25 or 64 pin
W (25 pin) arrangements of semi-insulated or non-insulated pins

Secret PRO Fractional CO2 / 10,600 nm / 2 MHz Up to 30 W (up to 20 – 5,000 μs / Contact mfr. Surgical CO2 handpiece available. RF Microneedling tips are
RF Microneedling 175 mJ) / 70 W (64 50 – 950 ms gold-plated for biocompatibility, 0.25 mm thin (33G), 25 or 64 pin
pin), 25 W (25 pin) arrangements in semi-insulated or non-insulated.

DEKA
SmartXide DOT Fractional CO2 10.6 μm 50 W max. 200 – 2,000 μs Contact mfr. DOT Scanner and Free hand handpiece; touch screen monitor,
Stack feature, Smart Track delivery mode, Smart Pulse, patient
database, CW, PW, traditional and fractional scanning modes
available.

SmartXide2 Fractional CO2 10.6 μm 80 W max. 100 – 2,000 μs Contact mfr. PSD technology with selectable pulse shape (SP, DP, UP, HP, PW,
CW, traditional and fractional scanning modes available), DOT/RF
scanner with RF feature, Free hand, TFT touch screen monitor,
Stack and Smart Track delivery mode, multimedia built-in training
videos, huge patient database with videos and photos. User
protocol storage. Optional diode laser module. Multidisciplinary.

SmartXide Touch Fractional CO2 10.6 μm 60 W max. 100 – 2,000 μs Contact mfr. PSD technology with selectable pulse shape (SP, DP, HP, PW, CW,
traditional and fractional scanning modes available), DOT/RF
scanner with RF feature, Free hand, TFT touch screen monitor,
Stack and Smart Track delivery mode, multimedia built-in training
videos, huge patient database with videos and photos. User
protocol storage. Multidisciplinary.

SmartXide Tetra Fractional CO2 10.6 μm 50 W max. 100 – 2,000 μs Contact mfr. PSD technology with selectable pulse shape (SP, DP, HP, PW, CW,
traditional and fractional scanning modes available), DOT/RF
scanner, Free hand, TFT touch screen monitor, Stack and Smart
Track delivery mode, huge patient database. User protocol
storage. Multidisciplinary.

HELIX Fractional CO2 / 10.6 μm / 157 nm 70 W max 10600 nm: 0.4 ms - 4 Contact mfr. Two wavelengths sequentially used with different patterns. PSD
1570 nm ms 1570 nm: 0.4 ms technology with selectable pulse shape (SP-DP-HP-PW-CW,
- 12 ms traditional & fractional scanning modes available), DOT/RF
scanner, free hand, TFT touch screen monitor, Stack and Smart
track delivery mode. Storing user's protocols. Multidisciplinary.

Fotona
SP Dynamis Nd:YAG / Er:YAG 1064 nm / 2940 nm Up to 600 J/cm2 0.1 – 50 ms Contact mfr. F-Runner, fractional Er:YAG scanner: 250 μm spot size, 168 mm2
Tx area. Er:YAG handpieces: 0.25 - 12 mm spot sizes.

XS Dynamis Er:YAG 2940 nm Up to 500 J/cm2 0.1 – 1.5 ms Contact mfr. Same as above.

StarWalker MaQX Nd:YAG Q-Switch 523 nm, 585 nm, Up to 300 J/cm2 580 ps, 0.6 – 50 ms, Contact mfr. R28, R29, R58, R585, R650, FS20, FS20A, FS20B, FS50, up to
Pico / Nano 650 nm, 5 ns / Hybrid Pico in 20 mm spot size.
1064 nm Nano, Fractional

TimeWalker Er:YAG 2940 nm 0.6 – 65 J/cm2 N/A Contact mfr. FS01 and PSO3x.

Lutronic Aesthetics
eC02 Plus CO2 Fractional Laser 10600 nm Up to 240 mJ 40 - 1,000 us; 1 - 5 ms Contact mfr. Customizable fractional CO2 treatments with advanced
capabilties to safely deliver laser resurfacing to lighten and
brighten patient complexions, including the reduced appearance
of acne scars.

Genius Bipolar Fractional RF N/A 50 W 10 - 1000 ms Contact mfr. N/A

Microneedling

Hollywood Spectra Nd:YAG Nano- 1064 / 532 nm Up to 1.4 J 5 ns, and 0.3 ms Contact mfr. Proven short-pulse platform for reducing unwanted pigment and
Acoustic Laser Optional Dye HPs: stimulating collagen with low downtime. HyperSurge, IntelliBeam
585 / 650 nm and MDF Microbeam technologies included as standard for
complete lightening and brightening treatment benefits. Exclusive
Hollywood Laser Peel and AcnePeel treatments.

Ultra Thulium Laser 1927 nm 1 - 20 mJ at 20 W N/A Contact mfr. Highest powered non-ablative fractional thulium laser is fully
customizable to all patient skin types, year round. Reduces
pigment and stimulates collagen with minimal patient downtime.
Optional serums and cooling masks can complement the
experience and allow for new treatment capabilities.

MRP
EDGE One Fractional CO2 Laser Fractional CO2 Laser N/A N/A N/A Contact mfr. EDGE pulse-mode with a very high power, extremely short
pulses, including the VanityPeel, no downtime procedure for
refreshing skin.

ZianMed
ReviVa CO2 Fractional CO2 1064 nm / 532 nm Up to 40 J/cm2 Adjustable Contact mfr. Scanner handpiece, surgical handpieces (.1 mm / .05 mm),
0.1 ms – 10 ms gynecological attachments.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 109

 Supplier Device Wavelength (nm) Energy Pulse Price Accessories
Product Name Type Output (Joules) Length

Advalight
ADVATx Diode 589 nm / 1319 nm Up to 40 J/cm2 Variable Contact mfr. Included scanner handpiece and optional foot pedal.

BENEV Company, Inc.

Sylfirm X Emerging Dual Wave RF N/A N/A Pulse Wave Mode: MSRP Sylfirm X Standard and XE Tip
Microneedling System 30 msec - 60 msec; $149,000
Continuous Wave Mode:
120 msec - 300 msec

SmartLux Mini SLD Phototherapy Blue (415 – 425 nm), 75 W/cm3 ~ 90 W/cm3 N/A MSRP N/A
Device Red (630 – 640 nm), $13,000
Infrared (820 – 830 nm)

Cutera
xeo Laser / Limelight 1064 nm / 520 – 1100 nm 300 J/cm2 / ≤30 J/cm2 Up to 300 ms / Contact mfr. No per treatment consumables. All accessories included.
Automatic

excel V+ Nd:YAG Laser 585 nm / 1064 nm Up to 300 J/cm2 Up to 60 ms Contact mfr. Dermastat 1 mm and 2 mm pens.

DEKA
Synchro FT Multifunctional Platform 1064 nm Nd:YAG / 700 J/cm2 (max) SP From 0.8 – 10 ms SP; Contact mfr. Five different application-specific handpieces. Top hat
IPL: 500 nm, 520 nm, and LP / 160 J (max) from 2 – 30 ms LP (1-3 technology and Auto Spot Size Recognition System;
550 nm; 600 nm; energy per pulse pulses) / From 3 – 8 ms contact cooling or optional external cooling connections;
650 nm delivery pulse settings available; patient database
and protocols. IPL: five optional filters, 30,000 shots
guaranteed. No disposables.

MiniSilk FT Pulsed Light System 500 nm, 520 nm, 2 – 2.5 J/cm2 2 – 85 ms (1-3 pulses) Contact mfr. Interchangeable snap-on filters; integrated skin contact
550 nm; 600 nm; cooling; lamp water cooling; transportable. 3.1 cm2 or 6.2
650 nm Filter cm2 spot area available. IR filter available for increased
skin tightening.

Synchro REPLA:Y Multifunctional Platform 755 nm Alexandrite / 63.5 J (max) – 125 W From 2 – 50 ms (single Contact mfr. Alex emission: 5 Hz and high power (125 W) system.
1064 nm Nd:YAG / (max) / LP: 120 J – 180 pulse); from 2 – 40 ms Nd:YAG laser module: 180 W with up to 27,000 W pulse
IPL: 500 nm; 520 nm; W (max); SP: 120 J (double pulse) / From 2 peak power; three delivery pulse design and adjustment
550 nm; 600 nm; (max) / 160 J (max) – 50 ms SP mode; from feature for Alexandrite and Nd:YAG. Twelve application
650 nm energy per pulse 0.2 – 12 ms LP mode / handpieces up to 24 mm. Auto Spot Size Recognition
From 3 – 8 ms System. Top hat technology; contact cooling or optional
external cooling connections; patient database and
protocols; IPL: five optional filters with enhanced vascular
capabilities; 500 G. No disposables.

Motus AY High Frequency 755 nm / 1064 nm Up to 30 J / From 2 – 50 ms (single Contact mfr. Transportable device, integrated Peltier skin contact
Alexandrite / Nd:YAG up to 60 J pulse); from 4 – 80 ms cooling. 500 nm, 520 nm, 550 nm; 600 nm; 650 nm
Laser (Twin pulse) / From 2 – vascular lesion application via standard optional
50 ms SP mode; from handpieces. Up to 20 mm spot area available with up to
0.2 – 12 ms LP mode 10 Hz rep. rate on both Nd:YAG and Alex wavelengths.
DEKA’s proprietary new Mòvèo technology functionality
for painless and smokless hair removal. Additional
standard handpiece for pigmented lesions, skin
rejuvenation and other dermatology indications.

LUXEA Multifunctional Platform Lilac; 6.2 cm2 Single Pulse: Contact mfr. Flexible multifunctional platform; several handpieces with
Viridis; interchangeable from 3 – 50 ms; integrated peltier skin contact cooling. Different filter
Sparks filters: 550 nm, 600 from 5 – 50 ms; solutions for different vascular lesion treatment needs. Up
nm and 650 – 6 – 30 ms to 6 Hz rep rate available. Additional
1200 nm. 2.1 cm2 standard handpiece for HR, skin rejuvenation and other
integrated 500 – dermatology indications. Contact cooling and delivery
677 nm and 854 – pulse settings available; up to 120,000 shots guaranteed
1200 nm (band pass) IPL. No disposables.
filter called 500 G.
2x2 mm/3x3 mm spot
sizes. 1064nm Nd:YAG
Laser: 2.5 mm/
4 mm/6 mm/10 mm
spot sizes.

Motus AZ+ High Power and 755 nm Alexandrite; Up to 31 J (62W); Single mode pulse Contact mfr. Transportable device, integrated Peltier skin contact
Frequency Alexandrite 1064 nm Nd:YAG Up to 63 J (94W) length 2 – 50 ms, cooling; hair removal, pigmented and vascular lesion
& Nd:YAG Laser Burst Pulse length treatments applied through either proprietary new Mòvèo
4 – 80 ms, Total burst Technology functionality for total painless and smokeless
length 14 – 300 ms; handpieces or standard up to 20 mm spot size optional
1 – 10 Hz rep. rate. handpieces. Up to 10 Hz rep. rate on both Nd:YAG
and Alexandrite wavelengths. 180° wide touch screen,
adjustable display for optimal view during sessions, high
power 1200 micron fiber connectivity and automatic
handpiece recognition with no need to turn machine off.

Fotona
SP Dynamis Nd:YAG / Er:YAG 1064 nm / 2940 nm Up to 600 J/cm2 0.1 – 50 ms Contact mfr. F-Runner, fractional Er:YAG scanner: 250 μm spot size, 168
mm2 Tx area. S-Runner, Er:YAG scanner: 4 mm spot size, 16
cm2 Tx area. S-11: Nd:YAG scanner: 42 cm2 Tx area. Er:YAG
handpieces: 0.25 - 12 mm spot sizes; Nd:YAG handpieces:
2 - 20 mm spot sizes.

XP-2 Focus Nd:YAG 1064 nm Up to 300 J/cm2 0.1 – 50 ms Contact mfr. Nd:YAG handpieces: 2 - 10 mm spot sizes.

XP MAX Nd:YAG 1064 nm Up to 600 J/cm2 0.1 – 300 ms Contact mfr. S-11: Nd:YAG scanner: 42 cm2 Tx area. Nd:YAG
handpieces: 2 - 20 mm spot sizes.

QX MAX Nd:YAG Q-Switched / 1064 nm, 532 nm, Up to 160 J/cm2 5 – 20 ns, 250 μs Contact mfr. Handpieces: 2 - 8 mm spot sizes.
Long Pulse 585 nm, 650 nm

SP Spectro Nd:YAG / Er:YAG 1064 nm / 2940 nm Up to 600 J/cm2 N/A Contact mfr. F-Runner, fractional Er:YAG scanner: 250 μm spot size, 168
mm2 Tx area. S-Runner, Er:YAG scanner: 4 mm spot size, 16
cm2 Tx area. S-11: Nd:YAG scanner: 42 cm2 Tx area. Er:YAG
handpieces: 0.25 - 12 mm spot sizes; Nd:YAG handpieces:
2 - 20 mm spot sizes.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

110 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 Supplier Device Wavelength (nm) Energy Pulse Price Accessories
Product Name Type Output (Joules) Length
Fotona (Continued)
XP Spectro Nd:YAG / Long Pulse 1064 nm Up to 600 J/cm2 0.1 – 50 ms Contact mfr. S-11 Nd:YAG scanner: 42 cm2 Tx area. Nd:YAG handpieces:
2 - 20 mm spot sizes.

XS Dynamis Er:YAG 2940 nm Up to 500 J/cm2 0.1 – 1.5 ms Contact mfr. F-Runner, fractional Er:YAG scanner: 250 μm spot size, 168
mm2 Tx area. S-Runner, Er:YAG scanner: 4 mm spot size, 16
cm2 Tx area. Er:YAG handpieces: 0.25 - 12 mm spot sizes.

XP Focus Nd:YAG / Long Pulse 1064 nm Up to 600 J/cm2 0.1 – 50 ms Contact mfr. Standard handpiece: R31/R32 with 2 - 8 mm spot sizes;
Nd:YAG handpieces: 2 - 20 mm spot sizes.

StarWalker MaQX Nd:YAG Q-Switch Pico / 523 nm, 585 nm, 650 nm, Up to 300 J/cm2 580 ps, 0.6 – 50 ms, Contact mfr. R28, R29, R58, R585, R650, FS20, FS20A, FS20B, FS50,
Nano 1064 nm 5 ns / Hybrid Pico in up to 20 mm spot size.
Nano, Fractional

TimeWalker Nd:YAG 1064 nm 6 – 150 J/cm2 7 – 25 ms Contact mfr. R33T.

Lasering USA
Velure S5 MiXto VX LBO Diode 532 nm 0.1 – 5 W 10 – 1,000 ms $29,500 MiXto VX fractional scanner for non-ablative skin
rejuvenation. Focusing handpieces with spot sizes of 0.3
mm, 0.5 mm, 1.0 mm, 1.5 mm. No disposables.

Velure S5 LBO Diode 532 nm 0.1 – 5 W 10 – 1,000 ms $21,500 Focusing handpieces with spot sizes of 0.3 mm, 0.5 mm, 1.0
mm, 1.5 mm. No disposables.

Velure S800 HP Diode 808 nm 10 – 600 J/cm2 10 – 1,000 ms $32,500 2.5 mm spot size handpiece.

Lutronic Aesthetics
Clarity II Alexandrite and Nd:YAG 755 / 1064 nm Up to 600 J/cm2 0.1 - 300 ms Contact mfr. Digitally-based 755 / 1064 nm platform that enables 2X
laser faster treatment coverage speed. Standard spots of
2 - 24 mm are included with single fiber, and advanced
handpiece with cryogen cooling to help facilitate the
treatment of common vascular lesions.

DermaV Nd:YAG laser 1064 / 532 nm Up to 600 J/cm2 0.1 - 300 ms Contact mfr. Digitally-based Nd:YAG platform that includes cryogen
cooling with 532 nm and exclusive multi-pulse
applications to effectively treat all vascular and pigmented
lesions. Standard spots of 2 - 16 mm are included
with single fiber, advanced handpiece, IntelliTrak and
Temperature Sensing.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

Renuva
Renuva is a ground-breaking treatment that restores age-
related volume loss, adds contour and smooths irregulari-
ties. Over time, Renuva is replaced with your body’s own
fat – leaving you with lasting, age-defying results – for a
look that is still you, only better!

MTF Biologics: (732) 661-0202 / (800) 946-9008 or visit www.mtfbiologics.org / www.myRenuva.com

ClearLase Pico & ReViva

ClearLase Pico uses the latest technology ETHEREA-MX & ZYE LASER Platforms Suite
dual wavelengths, for safe and effective tattoo ETHEREA-MX is the entry-level laser platform with multiple
removal, pigmented lesion destruction and solid-state LASERs and light-based handpieces, including the
skin rejuvenation with minimal heat, suitable one-of-kind 1,340 nm Nd:YAP ProDeep for subdermal fractional
for various skin types and melasma treatment. resurfacing, which provides skin rejuvenation from inside out
The ReViva fractional CO2 offers both ablative from the deepest skin layers, and the unique handPICO, first
and non-ablative resurfacing for skin rejuvena- and only Nd:YAG 1,064 nm / 532 nm picosecond handpiece.
tion, catering to various skin types. Surgical ZYE YAG and ZYE ALX are the world’s first superplatform, with
handpieces allow for lesion ablation and cutting, the ALX 755-nm for hair removal or YAG 1,064 nm for vascular
making it a versatile all-in-one device. lesions and advanced skin rejuvenation.

ZianMed: (727) 827-8090 or visit

Vydence Medical: (303) 588-1602 or visit www.laser.vydence.com/platforms
www.zianmed.com

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 Supplier Product Technology Applications Price

AMA Meditime Curestem Premium Cell Healer OPTI-3M SYSTEM Created with proprietary technology, OPTI-3M SYSTEM Contact mfr.
C20 + Skin Relaxer containing explosive growth energy of cell regeneration and
immunity control.
BENEV Company, Inc. Exosomes Regenerative Complex Stem cell derived lyophilized exosomes with potent Post treatment and professional use only. A post care "topical" Starting at
growth factors, peptides, coenzymes, minerals, treatment solution. $70/Tx
amino acids and vitamins to rejuvenate and
moisturize the skin.
Exosomes Regenerative Complex + Same technology as Exosome Regenerative Complex Post treatment and professional use only. A post care "topical" Starting at
but more powerful, more potent and faster results to treatment solution. $106/Tx
intensively rejuvenate and moisturize the skin and scalp.
EXO Balm Exosome and intensive hydrators to optimize treatment Post treatment and home-care use. A post care "topical" Starting at
results and reduce inflammation and downtime. treatment solution. $70/box

BTL Industries, Inc. Emsella HIFEM All forms of female and male urinary incontinence. Contact mfr.

Congela Biocosmetics JuveXO Premium MSC-derived secretome rich in growth Pre- and post-treatment topical serum for common skin concerns. Contact mfr.
factors, exosomes, collagen, HA and more. For professional use.
JuveXO-LYO Same powerful technology as JuveXO, now available Pre- and post-treatment topical serum for common skin concerns. Contact mfr.
in lyophilized form. For professional use.
JuveXO-H Premium secretome combining JuveXO with powerful Pre- and post-treatment topical serum for common hair concerns. Contact mfr.
recombinant proteins designed for hair. For professional use.

Cutera AviClear 1726 nm Laser Mild, moderate and severe acne in all skin types. Contact mfr.

DEKA PHYSIQ EMS and TENS device; EMS and TENS Technology 4 EMS mode for the prevention or impedance of disuse atrophy; Contact mfr.
Pads with EMS / TENS; electrodes; Variable maintaining or increasing the range of motion, muscle
re-education, relaxation of muscle spasms, increasing local blood
circulation; immediate post-surgical stimulation of calf muscles to
prevent venous thrombosis. In TENS mode PHYSIQ is intended
for symptomatic relief and management of chronic, intractable
pain, post-surgical acute pain and post-traumatic acute pain.

Dp Derm MG-EXO-SKIN Exosomes Utilizing one of the most exciting emerging technologies – Contact mfr.
exosomes – MG-EXO-SKIN™ is a regenerative, biomimetic
and multipotent meso-glide that removes the complications
of autologous procedures. Specially designed to be paired
with microneedling but can be used post energy based device
treatments as well.

Fotona StarWalker MaQX Q-Switched Pico/Nano (523 nm, 585 nm, 650 nm, StarWalker FracTAT Tx creates micro-size holes in skin over the Contact mfr.
1064 nm) tattoo area prior to the main laser procedure. This pretreatment
avoids the ‘frosting’ effect and allows shorter time between
multiple passes, reducing the number of Tx sessions.
TimeWalker 2940 nm Er:YAG / 1064 nm Nd:YAG Fotona4D non-invasive facelift, SmoothEye, LipLase, vascular, acne, Contact mfr.
hair removal, fractional and full-field resurfacing, benign lesions and
photobiomodulation.
HIRONIC Co., Ltd. NEW DOUBLO MFU / RF / combined function with MFU and RF Face lifting, skin rejuvenation, body contouring and wrinkles Contact mfr.
treatment.
SILKRO RF microneedling, RF needle, RF circle and RF vaginal Skin rejuvenation, collagen remodeling, acne scars, wrinkles and Contact mfr.
vaginal treatment.
PICOHI 300 picosecond Nd:YAG Laser Tattoo removal, pigment lesions and skin rejuvenation. Contact mfr.

Med Results Act O’ Feel Total fibroblast support to enhance volumizing, Post treatment and professional use only. A post care topical $8/ml
lifting, brightening and rejuvenating effect. Contains treatment sterile vial.
fragmented hyaluronic acid, amino acids, glutathione
and vitamin C.
Act O’ Reverse Total fibroblast support to enhance volumizing, Post treatment and professional use only. A post care topical Starting at
lifting, brightening and rejuvenating effect. Contains $20/Tx
treatment sterile vial.
fragmented hyaluronic acid, amino acids, glutathione
and vitamin C.
Plexr Plus Advanced non-invasive device that uses plasma
FDA-cleared for the removal and destruction of skin lesions and Contact mfr.
innovation to provide state-of-the-art treatments and
satisfactory clinical results. Offers a comprehensive tissue coagulation. Can be used to remove excess skin from
range of modalities, including non-ablative, semi- wrinkles, neck, face, eyelids and more.
ablative and ablative, enabling you to choose the
modality that best matches the skin's characteristics
and needs.

SHEnB Co, Ltd. VirtueRF Advanced cooling system, integrated pulsed RF Coagulate the surrounding tissue and transmitting Contact mfr.
system, integrated energy control system, minimum RF micro current deep inside the tissue by using microneedles or
depth control system with three types of hand pieces single pin tips.
(smart RF, deep RF and exact RF) in one platform.
VIVACE (VYBE RF) Selection of two high frequency mode (1MHz, 2MHz) Deliver high energy to dermis layer. Contact mfr.
with gold plated 36 pin needle TIP and two different
LED mode during treatment.
Diode laser with the two wavelengths of 635 nm Electric positioning cart Contact mfr.
AF Laser
and 405 nm. Energy transfer method is scan-type.
AF laser features vision camera, positioning system,
automatic UV sisinfection (LED) and integrated
customization system.
PlaDuo Jet-type plasma generator, 1-15 level energy control, N/A Contact mfr.
up to 3Hz shot speed, microwave method, highly
durable configuration, large capacity gas can of up
to 10 L.
Sofwave Sofwave Ultrasound FDA cleared for lifting of the face and neck using ultrasound Contact mfr.
technology.

Sylton, Inc. Observ Skin Analysis System IOS (IPad) supported imaging system Supportive digital imaging system which enables aesthetic Contact mfr.
practitioners to have an informative consultation with regards to
rejuvenation and beautification treatments.

Toskani US Exceed Mesoneedling Face, body and hair Contact mfr.

ZianMed ClearLaze Pico Pico Second Laser 1064 nm wavelength removes tattoos for the following colors: black, Contact mfr.
brown, green, blue and purple. Treatment of benign pigmented
lesions. 532 nm wavelength removes tattoos for the following colors:
red, yellow and orange. Treatment of benign pigmented lesions.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

112 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

Supplier Device Wavelength (nm) Energy Pulse Price Accessories
Product Name Type Output (Joules) Length
Cutera
xeo + prowave Laser / IPL 1064 nm / 680 – 1100 nm 300 J/cm2 / ≤30 J/cm2 Up to 300 ms / Automatic Contact mfr. No per treatment consumables. All accessories
included.

excel HR Laser 755 nm, 1064 nm Up to 300 J/cm2 Up to 300 ms Contact mfr. No per treatment consumables. All accessories
included.

excel V+ Laser 532 nm, 1064 nm Up to 300 J/cm2 Up to 60 ms Contact mfr. 1 mm and 2 mm Dermastat pens.

DEKA
MiniSilk FT Pulsed Light System 500 nm, 520 nm, 550 nm; 2 – 2.5 J/cm2 3 – 8 ms (1-3 pulses) Contact mfr. Interchangeable snap-on filters; integrated skin contact
600 nm; 650 nm Filter cooling; lamp water cooling; transportable. 3.1 cm2
or 6.2 cm2 spot area available. IR filter available for
increased skin tightening.

Synchro REPLA:Y Multi-Functional Platform 755 nm Alexandrite / 63.5 J (max) – 125 W From 2 – 50 ms (single Contact mfr. Alex emission: 5 Hz and high power (125 W) system.
1064 nm Nd:YAG / (max) / LP: 120 J - pulse); from 2 – 40 ms Nd:YAG laser module: 180 W with up to 27,000 W
IPL: 500 nm; 520 nm; 180 W (max); SP: 120 (double pulse) / From pulse peak power; three delivery pulse designs and
550 nm; 600 nm; 650 nm J (max) / 160 J (max) 2 – 50 ms SP mode; from adjustment feature for Alexandrite and Nd:YAG. Twelve
energy per pulse 0.2 – 12 ms LP mode / application handpieces up to 24 mm. Auto Spot Size
From 3 – 8 ms Recognition System. Top hat technology; contact
cooling or optional external cooling connections;
patient database and protocols; IPL: five filters
(optional) with enhanced vascular capabilities; 500 G.
No disposables.

Synchro FT Multi-Functional Platform 1064 nm Nd:YAG / 700 J/cm2 (max) SP From 0.8 – 10 ms SP; from $55,990 Five application-specific handpieces. Top hat
IPL: 500 nm, 520 nm, and LP / 160 J (max) 2 – 30 ms LP (1-3 pulses) / technology and Auto Spot Size Recognition
550 nm; 600 nm; 650 nm energy per pulse From 3 – 8 ms System; contact cooling or optional external cooling
connections; delivery pulse settings available; patient
database and protocols. IPL: five optional filters, 30,000
shots guaranteed. No disposables.

Motus AX High Frequency 755 nm Up to 30 J From 2 – 50 ms (single Contact mfr. Transportable device, integrated Peltier skin contact
Alexandrite Laser pulse); from 4 – 80 ms cooling, 20 mm spot area available with up to 10
(Twin pulse) Hz rep. rate. Proprietary new Mòvèo technology
functionality for painless and smokless hair removal.

Motus AY High Frequency 755 nm / 1064 nm Up to 30 J / up to From 2 – 50 ms (single Contact mfr. Transportable device, integrated Peltier skin contact
Alexandrite / Nd:YAG 60 J pulse); from 4 – 80 ms cooling. Up to 20 mm spot area with up to 10 Hz rep.
Laser (Twin pulse) / From 2 – 50 rate on both Nd:YAG and Alex wavelengths. Proprietary
ms SP mode; from 0.2 – 12 new Mòvèo technology functionality for painless and
ms LP mode smokless hair removal. Additional standard handpiece
for vascular, skin rejuvenation and other dermatology
indications.

LUXEA Multifunctional Platform Lilac; 6.2 cm2 Single pulse: Contact mfr. Flexible multifunctional platform; several handpieces
Ruber; interchangeable from 3 – 50 ms; with integrated peltier skin contact cooling. Different
Sparks; filters: 550 nm, 600 from 8 – 50 ms; filter solutions for different hair removal needs (shot by
Vivid nm and 650 – 6 – 30 ms; shot, IPL, laser, etc.). Up to 10 Hz rep rate available on
1200 nm. 8.3 cm2 15 – 200 ms. laser wavelengths. Additional standard handpiece for
integrated 550 – other applications like vascular, skin rejuvenation and
1200 nm filter. 1064 nm other dermatology indications. Contact cooling and
Nd:YAG Laser: 2.5 mm/ delivery pulse settings available; up to 120,000 shots
4 mm/6 mm/10 mm guaranteed IPL. No disposables.
spot sizes. 808 nm
Diode Laser: 10x13
mm spot size.
Motus AZ+ High Power and 755 nm Alexandrite; Up to 31 J (62W); Single mode pulse length Contact mfr. Transportable device, integrated Peltier skin contact
Frequency Alexandrite & 1064 nm Nd:YAG Up to 63 J (94W) 2 – 50 ms, Burst Pulse cooling; hair removal, pigmented and vascular lesion
Nd:YAG Laser length 4 – 80 ms, Total treatments applied through either proprietary new
burst length 14 – 300 ms; Mòvèo Technology functionality for total painless and
1 – 10 Hz rep. rate. smokeless handpieces or standard up to 20 mm spot
size optional handpieces. Up to 10 Hz rep. rate on both
Nd:YAG and Alexandrite wavelengths. 180° wide touch
screen, adjustable display for optimal view during
sessions, high power 1200 micron fiber connectivity
and automatic handpiece recognition with no need to
turn machine off.

Motus AZ High Power and 755 nm Up to 31 J (62W) Single mode pulse length Contact mfr. Transportable device, integrated Peltier skin contact
Frequency Alexandrite 2 – 50 ms, Burst Pulse cooling; hair removal and pigmented lesion treatments
Laser length 4 – 80 ms, Total applied through either proprietary new Mòvèo
burst length 14 – 300 ms; Technology functionality for total painless and
1 – 10 Hz rep. rate. smokless handpieces or standard up to 20 mm spot
size optional handpieces. Up to 10 Hz rep. rate. 180°
wide touch screen, adjustable display for optimal
view during sessions, high power 1200 micron fiber
connectivity and automatic handpeice recognotion with
no need to turn machine off.
Fotona
SP Dynamis Nd:YAG / Er:YAG 1064 nm Up to 600 J/cm2 0.1 – 1.6 ms Contact mfr. S-11: Nd:YAG scanner: 42 cm2 Tx area. Nd:YAG
handpieces: 2 - 20 mm spot sizes.

XP MAX Nd:YAG 1064 nm Up to 600 J/cm2 0.1 – 1.6 ms Contact mfr. Same as above.

QX MAX Nd:YAG Q-Switched / 1064 nm, 532 nm, 585 nm, Up to 160 J/cm2 250 μs Contact mfr. Handpieces: 2 - 8 mm spot sizes.
Long Pulse 650 nm

StarWalker MaQX Nd:YAG Q-Switch Pico / 523 nm, 585 nm, 650 nm, Up to 300 J/cm2 580 ps, 0.6 – 50 ms, 5 ns / Contact mfr. R28, R29, R58, R585, R650, FS20, FS20A, FS20B,
Nano 1064 nm Hybrid Pico in Nano, FS50, up to 20 mm spot size.
Fractional

TimeWalker Nd:YAG 1064 nm 5 – 75 J/cm2 0.6 – 2 ms Contact mfr. R33T and R30Y.
MRP
Bare 808 Diode Laser Diode Laser Hair Removal Gold-standard 808 nm N/A N/A Contact mfr. Square waveform, multi-pulse mode for optimal
diode treatment and safety. 14 mm x 14 mm spot size.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 113

Supplier Device Wavelength (nm) Energy Pulse Price Accessories
Product Name Type Output (Joules) Length

Advalight
ADVATx Diode 589 nm / 1319 nm Up to 40 J/cm2 Variable Contact mfr. Included scanner handpiece and optional foot pedal.

BENEV Company Inc. SLD Phototherapy Blue (415 – 425 nm), 75 W/cm3 ~ 90 W/cm3 N/A MSRP $13,000 N/A
SmartLux Mini Device Red (630 – 640 nm),
Infrared (820 – 830 nm)

Cutera
AviClear Laser 1726 nm Up to 100 W Up to 50 ms Contact mfr. No per treatment consumables. All accessories included.
2
excel V+ Laser 532 nm, 1064 nm Up to 300 J/cm Up to 60 ms Contact mfr. 1 mm and 2 mm Dermastat pens.

DEKA
SmartXide DOT Fractional CO2 10.6 μm 50 W max 200 – 2000 μs Contact mfr. DOT Scanner and Free hand handpiece; touch screen monitor,
Stack feature, Smart Track delivery mode, Smart Pulse, patient
database, CW, PW, traditional and fractional scanning modes
available.

SmartXide2 Fractional CO2 10.6 μm 80 W max 100 – 2000 μs Contact mfr. PSD technology with selectable pulse shape (SP, DP, UP, HP, PW,
CW, traditional and fractional scanning modes available), DOT/
RF scanner with RF feature, Free hand, TFT touch screen monitor,
Stack and Smart Track delivery mode, multimedia built-in training
videos, huge patient database with videos and photos. User
protocol storage. Optional diode laser module.

SmartXide Touch Fractional CO2 10.6 μm 60 W max 100 – 2000 μs Contact mfr. PSD technology with selectable pulse shape (SP, DP, HP, PW,
CW, traditional and fractional scanning modes available), DOT/
RF scanner with RF feature, Free hand, TFT touch screen monitor,
Stack and Smart Track delivery mode, multimedia built-in training
videos, huge patient database with videos and photos. User
protocol storage. Optional diode laser module. Multidisciplinary.

SmartXide Tetra Fractional CO2 10.6 μm 50 W max 100 – 2000 μs Contact mfr. PSD technology with selectable pulse shape (SP, DP, HP, PW,
CW, traditional and fractional scanning modes available), DOT/
RF scanner, Free hand, TFT touch screen monitor, Stack and
Smart Track delivery mode, huge patient database. User protocol
storage. Multidisciplinary.

Synchro FT Multi-Functional 1064 nm Nd:YAG / IPL: 700 J/cm2 (max) SP and From 0.8 – 10 ms Contact mfr. Five different application-specific handpieces. Top hat technology
Platform 500 nm, 520 nm, 550 nm; LP / 160 J (max) energy SP; from 2 – 30 ms and Auto Spot Size Recognition System; contact cooling or
600 nm; 650 nm per pulse LP (1-3 pulses) / optional external cooling connections; delivery pulse settings
From 3 – 8 ms available; patient database and protocols. IPL: five optional filters,
30,000 shots guaranteed. No disposables.

Synchro REPLA:Y Multi-Functional 755 nm Alexandrite / 63.5 J (max) – 125 W From 2 – 50 ms Contact mfr. Alex emission: 5 Hz and high power (125 W) system. Nd:YAG
Platform 1064 nm Nd:YAG / IPL: (max) / LP: 120 J – 180 (single pulse); from laser module: 180 W with up to 27,000 W pulse peak power;
500 nm, 520 nm, 550 nm; W (max); SP: 120 J (max) 2 – 40 ms (double three delivery pulse designs and adjustment feature for
600 nm; 650 nm / 160 J (max) energy pulse) / Alexandrite and Nd:YAG. Twelve application handpieces up to
per pulse From 2 – 50 ms SP 24 mm. Auto Spot Size Recognition System. Top hat technology;
mode; from 0.2 – contact cooling or optional external cooling connections; patient
12 ms LP mode / database and protocols; IPL: five filters (optional) with enhanced
From 3 – 8 ms vascular capabilities; 500 G. No disposables.

Motus AY High Frequency 755 nm / 1064 nm Up to 30 J / up to 60 J From 2 – 50 ms Contact mfr. Transportable device, integrated Peltier skin contact cooling. Up
Alexandrite / Nd:YAG (single pulse); from to 20 mm spot area with up to 10 Hz rep. rate available on both
Laser 4 – 80 ms (Twin Nd:YAG and Alex wavelengths. Proprietary new Mòvèo technology
pulse) / From 2 – functionality for painless and smokless hair removal. Additional
50 ms SP mode; standard handpiece for vascular, skin rejuvenation and other
from 0.2 – 12 ms dermatology indications.
LP mode
LUXEA Multifunctional Lazur 6.2 cm2 integrated 420 8 ms; 30 ms; Contact mfr. Flexible multifunctional platform; several handpieces with
Platform – 950 nm filter 50 ms integrated peltier skin contact cooling and TEMP selection. 6.2
cm2 spot at 3 Hz max rep. rate; short/medium/long pulse modes.

Motus AZ+ High Power and 755 nm Alexandrite; Up to 31 J (62W); Single mode Contact mfr. Transportable device, integrated Peltier skin contact cooling;
Frequency Alexandrite 1064 nm Nd:YAG Up to 63 J (94W) pulse length 2 hair removal, pigmented and vascular lesion treatments applied
& Nd:YAG Laser -- 50 ms, Burst through either proprietary new Mòvèo Technology functionality
Pulse length 4 for total painless and smokeless handpieces or standard up
-- 80 ms, Total to 20 mm spot size optional handpieces. Up to 10 Hz rep. rate
burst length 14 on both Nd:YAG and Alexandrite wavelengths. 180° wide touch
-- 300 ms; 1 -- 10 screen, adjustable display for optimal view during sessions, high
Hz rep. rate. power 1200 micron fiber connectivity and automatic handpiece
recognition with no need to turn machine off.

HELIX Fractional CO2 / 10.6 μm / 157 nm 70 W max 10600 nm: 0.4 ms Contact mfr. Two wavelengths sequentially used with different patterns. PSD
1570 nm - 4 ms 1570 nm: technology with selectable pulse shape (SP-DP-HP-PW-CW,
0.4 ms - 12 ms traditional & fractional scanning modes available), DOT/RF
scanner, free hand, TFT touch screen monitor, Stack and Smart
track delivery mode. Storing user's protocols. Multidisciplinary.

Fotona
SP Dynamis Nd:YAG / Er:YAG 1064 nm / 2940 nm Up to 600 J/cm2 0.1 – 50 ms Contact mfr. F-Runner, fractional Er:YAG scanner: 250 μm spot size, 168 mm2
Tx area. S-Runner, Er:YAG scanner: 4 mm spot size, 16 cm2 Tx area.
S-11: Nd:YAG scanner: 42 cm2 Tx area. Er:YAG handpieces: 0.25 - 12
mm spot sizes; Nd:YAG handpieces: 2 - 20 mm spot sizes.

XS Dynamis Er:YAG\ 2940 nm Up to 500 J/cm2 0.1 – 1.5 ms Contact mfr. F-Runner, fractional Er:YAG scanner: 250 μm spot size, 168 mm2
Tx area. S-Runner, Er:YAG scanner: 4 mm spot size, 16 cm2 Tx
area. Er:YAG handpieces: 0.25 - 12 mm spot sizes.

QX MAX Nd:YAG Q-Switched / 1064 nm, 532 nm, Up to 160 J/cm2 5 – 20 ns, 250 μs Contact mfr. Handpieces: 2 - 8 mm spot sizes.
Long Pulse 585 nm, 650 nm Accelera Pulse

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

114 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

Supplier Device Wavelength (nm) Energy Pulse Price Accessories
Product Name Type Output (Joules) Length
Fotona (Continued)
SP Spectro Nd:YAG / Er:YAG 1064 nm / 2940 nm Up to 600 J/cm2 N/A Contact mfr. F-Runner fractional Er:YAG scanner: 250 μm spot size, 168 mm2 Tx
area.w S-Runner Er:YAG scanner: 4 mm spot size, 16 cm2 Tx area.
S-11 Nd:YAG scanner: 42 cm2 Tx area. Er:YAG handpieces: 0.25 - 12
mm spot sizes; Nd:YAG handpieces: 2 - 20 mm spot sizes.
XP Spectro Nd:YAG / Long Pulse 1064 nm Up to 600 J/cm2 0.1 – 50 ms Contact mfr. S-11 Nd:YAG scanner: 42 cm2 Tx area. Nd:YAG handpieces: 2 - 20
mm spot sizes.
XP Dynamis Nd:YAG / Long Pulse 1064 nm Up to 600 J/cm 2
0.1 – 50 ms Contact mfr F-Runner fractional Er:YAG scanner: 250 μm spot size, 168 mm2
Tx area. S-Runner Er:YAG scanner: 4 mm spot size, 16 cm2 Tx
area. S-11 Nd:YAG scanner: 42 cm2 Tx area. Er:YAG handpieces:
0.25 - 12 mm spot sizes; Nd:YAG handpieces: 2 - 20 mm spot
sizes. S-11 Nd:YAG scanner: 42 cm2 Tx area. Nd:YAG handpieces:
2 - 20 mm spot sizes.
StarWalker MaQX R28, R29, R58, R585, R650, FS20, FS20A, FS20B, FS50, up to 20
Nd:YAG Q-Switch Pico 523 nm, 585 nm, 650 nm, Up to 300 J/cm2 580 ps, 0.6 – 50 Contact mfr.
/ Nano 1064 nm mm spot size.
ms, 5 ns / Hybrid
Pico in Nano,
Fractional
HIRONIC Co., Ltd.
GENTLO RF Microneedle N/A Level 1 ~ 10 N/A Contact mfr. Plasma handpiece, vaginal applicator, acne applicator.
PLASONIC Plasma N/A Level 1 ~ 5 N/A Contact mfr. Two types of handpieces: ultrasound / plasma.

Lutronic Aesthetics
Clarity II Alexandrite and 755 / 1064 nm Up to 600 J/cm2 0.1 - 300 ms Contact mfr. Digitally-based 755 / 1064 nm platform that enables 2X faster
Nd:YAG laser treatment coverage speed. Standard spots of 2 - 24 mm are
included with single fiber, and advanced handpiece with
cryogen cooling to help facilitate the treatment of common
vascular lesions.
DermaV Nd:YAG laser 1064 / 532 nm Up to 600 J/cm2 0.1 - 300 ms Contact mfr. Digitally-based Nd:YAG platform that includes cryogen cooling
with 532 nm and exclusive multi-pulse applications to effectively
treat all vascular and pigmented lesions. Standard spots of
2 - 16 mm are included with single fiber, advanced handpiece,
IntelliTrak and Temperature Sensing.
eC02 Plus CO2 Fractional Laser 10600 nm Up to 240 mJ 40 - 1,000 us; Contact mfr. Customizable fractional CO2 treatments with advanced
1-5 ms capabilties to safely deliver laser resurfacing to lighten
and brighten patient complexions, including the reduced
appearance of acne scars.
Hollywood Spectra Nd:YAG Nano-Acoustic 1064 / 532 nm Up to 1.4 J 5 ns and 0.3 ms Contact mfr. Proven short-pulse platform for reducing unwanted pigment and
Laser Optional Dye HPs: 585 stimulating collagen with low downtime. HyperSurge, IntelliBeam
/ 650 nm and MDF Microbeam technologies included as standard
for complete lightening and brightening treatment benefits.
Exclusive Hollywood Laser Peel and AcnePeel treatments.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

Luvo Darwin
Luvo Darwin is a multi-modality platform that provides premium technolo-
gies covering the essential treatments of an aesthetic practice. Lucent IPL,
Bare 808 diode LHR, Surface RF skin tightening and RF microneedling all
in one system with industry low consumable costs and a low purchase
price. Finally. Four Essential Modes. One Device. Half The Price.

Powered by MRP: (435) 731-8232 or visit www.mrp.io

BB CREAM Complexion Perfector

Manufactured by Martinni Beauty, this natural-looking, tone cor-
recting, radiating BB CREAM Complexion Perfector firms, moistur- JuveXO
izes and illuminates light to medium skin. This next-generation JuveXO® is a topical serum that harnesses the
formula is the ultimate age-reversing color corrector. It features extraordinary power of exosomes. Through the
bio-engineered growth hormone and argan stem cell technology, most cutting-edge biotechnology and decades
which lifts, tightens and reduces the appearance of fine lines and of research, JuveXO delivers a non-invasive
wrinkles, all while giving the skin a beautiful, natural glow. The key and nonsurgical method to revitalize and
ingredients are argan oil, resveratrol, copper tripeptide, niacina- rejuvenate the appearance of skin and hair.
mide, EGF and vita blu complex. JuveXO combines biology and cosmetics to
improve the look of damaged and aging tissue.

Congela Biocosmetics, LLC:

Martinni Beauty, Inc.: (888) 440-8811 or visit www.martinnibeauty.com
(833) 436-8372 or visit www.juvexo.com

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 115

 Supplier Device Energy Source Mechanism of Action Regulatory Status Price
(Europe and USA)

Allergan Aesthetics, an CoolSculpting Elite Cryolipolysis Cryolipolysis uses controlled cooling to safely and FDA cleared. Contact mfr.
AbbVie company effectively freeze stubborn fat with little to no downtime.
Cryolipolysis targets fat cells without damaging
surrounding tissue or skin. Fat cells die by apoptosis.
Treatment areas include the thigh, abdomen and flank,
along with bra fat, back fat, underneath the buttocks (also
known as banana roll) and upper arm.

CoolTone Magnetic muscle stimulation Magnetic muscle stimulation using Active Magnetic Pulse FDA cleared. Contact mfr.
programming causes involuntary muscle contractions
which strengthen the muscle fibers in the treated area,
resulting in a stronger, firmer and more toned appearance.
Treatment areas include the abdomen, glutes and thighs.

BTL Industries, Inc. Vanquish ME Selective RF Proprietary Selective Field RF with broad field applicator CE cleared. FDA cleared. Contact mfr.
delivering uniform energy for circumferential reduction of
the abdomen.

Exilis Ultra Focused RF and Ultrasound Simultaneous delivery of focused RF and ultrasound energy CE cleared. FDA cleared. Contact mfr.
with variable surface cooling delivers precise volumetric
heating of tissue for wrinkles, laxity, cellulite and body
contouring. Exilis patented applicators deliver maximum
thermal effect without costly consumables.

Emtone Combination RF and Targeted Simultaneous delivery of monopolar RF and Targeted FDA 510k clearance to provide Contact mfr.
Pressure Energy Pressure Energy to non-invasively treat all major a temporary reduction in the
contributing factors to cellulite. The simultaneous effect of appearance of cellulite, and
this combined energy results in disruption of old structures heating for the purpose of
followed by the synthesis of new healthy ones leading to a elevating tissue temperature
thickening of the dermis, relaxation of connectiove septae for medical conditions such as
and increase of elasticity. temporary relief of pain, muscle
spasms and increase in local
circulation.

Emsculpt HIFEM Supra maximal muscle contractions Cleared for strengthening, Contact mfr.
firming and toning of the
abdomen, arms, buttocks,
thighs and calves.

Emsculpt NEO Synchronized RF and HIFEM+ Simultaneous emission of patented Synchronized RF heating CE cleared, FDA cleared. Contact mfr.
and HIFEM+ induced supra-maximal muscle contractions
leading to non-invasive fat reduction, muscle growth, lipolysis
of the abdomen and thighs as well as strengthening, firming
and toning of the abdomen, buttocks, thighs, calves and arms.
For skin types I - VI.
Cutera truSculpt Monopolar RF Non-invasive fat reduction using monopolar RF heating with FDA cleared, CE marked, Contact mfr.
truControl technology that penetrates deep into the entire Health Canada.
fat layer creating selective apoptosis of the subcutaneous
adipose tissue.

truFlex Direct Bio-Electrical Muscle Stimulation Multi-Directional Stimulation (MDS) deploys a unique method FDA cleared, CE marked, Contact mfr.
of electrical muscle stimulation to target specific muscle Health Canada.
groups using three different treatment modes to strengthen,
tone, and firm the abdomen, glutes, and thighs with 15-minute
treatment options.
DEKA SmartLipo 6 1064 nm Nd:YAG Laser Lipolisi technology with more than 15 years of experience on CE cleared. FDA cleared. Contact mfr.
SmartLipo 10 patients. 6 W, 10 W and 18 W versions. Customized μPulsed
SmartLipo 18 Nd:YAG wavelength providing physiological contractions and
elimination of the fat with no inflammatory effects. Controlled
photomechanical effects, photo-coagulative action and a
photo-stimulative course for immediate skin tightening due to
flexible pulse design.

LIPO AI 1440 nm Nd:YAG Laser Novel NIR laser assisted liposuction device, based on artificial FDA cleared. Contact mfr.
intelligence algorithm and it is indicated for the surgical
incision, excision, vaporization, ablation and coagulation of
soft tissues. Further indicated for laser assisted lipolysis and
provides physicians with special views and real time feedback
controls (patent pending). AI Algorithm and customized
μPulsed Nd:YAG wavelength providing physiological
contractions and elimination of the fat with no inflammatory
effects. Controlled photo-mechanical effect, photo-coagulative
action and photo-stimulative course for immediate skin
tightening due to flexible pulse design.

Fotona SP Dynamis Nd:YAG 1064 nm, Er:YAG 2940 nm Laser assisted lipolysis, treatment of wrinkles; Photothermal - CE cleared. FDA cleared. Contact mfr.
heat generated by laser light.

XP-2 Focus Nd:YAG 1064 nm Same as above. CE cleared. FDA cleared. Contact mfr.

XP Dynamis Nd:YAG 1064 nm Same as above. CE cleared. FDA cleared. Contact mfr.

SP Spectro Nd:YAG 1064 nm, Er:YAG 2940 nm Same as above. CE cleared. FDA cleared. Contact mfr.

XP Spectro Nd:YAG 1064 nm Same as above. CE cleared. FDA cleared. Contact mfr.

HIRONIC Co., Ltd. SLIMUS 1060 nm Diode Laser with Vibration High penetration depth of 1060 nm diode laser with minimal FDA approved. CE marked. Contact mfr.
absorption in the dermis, effecting subcutaneous fat cells for
permanent elimination.

MICOOL-S Cooling Lipolysis + Vacuum Cooling energy is delivered to the subcutaneous fat layer CE marked. Contact mfr.
without any damage to surrounding tissues.
MRP Lipocel HIFU High Intensity Focused Ultrasound Painless, non-invasive, body contouring and fat reduction. N/A Contact mfr.
Focused Ultrasound Powerful 5C contact cooling to protect the epidermis and
allow the emission of higher-intensity energy for increased
effectivity.

MTF Biologics LipoGrafter Kit KVAC Syringe; Atraumatic Tissue Valve Single use kit to provide an all-in-one, closed system for N/A Contact mfr.
(AT Valve) autologous fat grafting.

Note: Data subject to change; please refer to Company Directory for supplier contact information. Not all devices are FDA cleared for the application(s) indicated.

116 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 Join innovative clinicians and scientists
from around the world in Baltimore,
Maryland, at the premier
international meeting in the
field of medical lasers
and energy-based
technologies.

The go-to meeting in the field of lasers and energy-based devices for
aesthetic medicine. Learn from the world’s leading experts about:

» Body Contouring » Practice Management

» Combining Injectables with Devices » Rejuvenation

» Complications and Legal Issues » Resurfacing

LEARN
» Face and Body Lifting/Tightening » Scar Treatment
» Hair Growth and Removal » Skin Cancer
» Laser Safety » Skin of Color from the best of the best about
» Laser-Assisted Drug Delivery » Skin Tightening the latest research, techniques,
» Pigmented Lesions » Tattoo Removal protocols and applications.
» Plastic Surgery » Vascular

Gain perspectives through workshops, featured

speakers, abstract sessions, hands-on learning
CONNECT
with professionals in laser and
labs, device demonstrations, clinical pearls,
energy-based medicine technology,
industry sponsored sessions and more!
safety and patient care.

REGISTER NOW! EXPLORE

the Exhibit Hall, featuring
ASLMS.ORG exhibitors showcasing new
technologies and equipment.

GET CONNECTED
#ASLMS2024

The American Society for Laser Medicine and Surgery, Inc. is the largest multi-disciplinary
professional organization dedicated to the development and application of lasers and related
technology for health care applications.
ADVATx
ADVATx is the apex of solid-state lasers, delivering high powered yellow
light and infrared laser energy without toxic pulse dye kits. With dual 589 nm
and 1319 nm wavelengths, ADVATx is FDA/CE-cleared to treat 25 indications
from vascular and pigmented lesions to scars, acne and wrinkle reduction.
ADVATx provides max versatility with clinical efficacy, user friendly controls,
no consumables and no social downtime!

Advalight: (888) 354-5551 or visit www.advalight.com

Galderma
We are advancing dermatology for every skin story
by empowering beauty in all forms. At Galderma,
Love Beauty Pro & Medical we embrace these differences and offer cutting-
Love Beauty Pro & Medical is the official edge, premium brands that fit people’s individual
exclusive U.S. distributor for LC Cell’s needs, across the full spectrum of dermatology
Renew, Bright, Hair, Anti-Aging Kit, Dual through aesthetics, consumer care and prescrip-
C and Hair Solution. Love Beauty Pro tion medicine. Galderma’s passion for education
& Medical is the official U.S. distributor and unique innovation enables our patients to truly
(exclusive to all states excluding WI, IL, embrace their individual skin story. Collaboration
MI, IN and OH) for WiQo’s PRX Derm is part of our DNA – a cultural driver for how we
Perfexion and PRX Intima Perfexion. interact within and beyond the company.

Love Beauty Professional & Medical: Galderma Laboratories, L.P.: (817) 961-5000 or
(877) 920-2281 or visit www.lovebeautypro.com/contact-us visit www.galderma.com/us

NEW DOUBLO
The NEW DOUBLO is a lifting device that combines HIFU and RF.
Combining RF and HIFU in one device, in a cross-examination manner,
results in increased treatment effectiveness and significantly shortened
treatment time.

HIRONIC Co., Ltd.: +82 31 525 7400 or visit www.hironic.com

MOTUS AZ+ Bright & Even Peel

The New MOTUS AZ+, 755 nm and 1064 nm laser platform, offers virtually A gentle professional peel that brightens and
painless and smokeless hair removal, pigmented lesions, vascular and resurfaces the skin to enhance the appearance
other procedures for all skin types. The DEKA’s proprietary new Moveo of skin tone, texture and visible brightness.
Technology handpieces (HR, PL, VL & SR) provides high degree comfort PCA SKIN® Bright & Even Peel can be used on
procedure with excellent results and tolerability scale. The New Moveo all skin types, including sensitive skin, and has
Glo allows sequential use of the four different four Move handpieces in been shown to provide an overall improvement
one session to provide excellence in virtually painless skin revitalization in uneven skin tone on all Fitzpatricks. Bright
treatments. MOTUS AZ+, allows for no stress procedures for users. The & Even Peel is proven to increase visible skin
wide view touch screen display and the full parameters control (three brightness after just one peeling session* as well
levels: soft-medium-high) allow physicians to tailor and perform treatments as increase skin glow and radiance.
on all patients with no trouble. A standard handpiece option available too. *Based on a 4 week case study with 15 subjects.

PCA Skin: (877) 722-7546 or

DEKA: +39 055 88 74 942 or visit www.dekalaser.com
visit www.pcaskinpro.com

118 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 Dynamis
Fotona leads the aesthetic industry with laser systems that
perform all major aesthetic treatments. By combining two
complementary wavelengths, the Fotona Dynamis laser is
a highly versatile, multi-purpose system that can perform
an exceptionally wide range of treatments with only one
device. Key treatments include, but are not limited to,
Fotona4D® non-invasive laser facelifting, TightSculpting
body contouring, acne and acne scar revision, pigmented
lesions, vascular lesions, onychomycosis, permanent hair
removal and NightLase® non-invasive snoring treatment.

Fotona: (972) 598-9000 or visit www.fotona.com/us

DP4 Microneedling Pen

The DP4 microneedling pen from Dp Derm
is an advanced fully digital fractional micro-
channeling device. It combines direct drive,
bluetooth, dual power and turbo-cut battery
systems to provide the fastest and most efficient FF3 Biointensive GF
microneedling treatment possible. FDA cleared Vivant’s FF3 Biointensive GF uses GFP complex to promote neocollagenesis,
for treating facial acne scars, it features a organize collagen fibers and regulate cell turnover leaving estrogen depleted skin
dedicated scar treatment (ST) setting, as well feeling plumper. GFP complex is the novel joining of vitamin A and growth factor
as RFID chip integration to allow for continuous technology with select amino acids and alpha hydroxy acids to repair the skin’s
needle calibration for precise, reliable and drag- support matrix at a cellular level.
free needle penetration.

Dp Derm: (305) 552-0550 or

Vivant Skin Care: (800) 984-8268 or visit www.vivantskincare.com
visit www.dpderm.com

DR. CYJ iDR/pDR Hair Mist & Mask

DR. CYJ iDR/pDR Hair Mist & Mask are products that work on
damaged hair to restore damaged keratin proteins, making hair
shiny and soft. You can see instant effects within five minutes of
using the product, and the effects last for two to three days. It
not only prevents damage when used before frequent dyeing,
perming, or drying, but also restores damaged hair.

Caregen Co., Ltd.: +82-31-420-9200 or visit www.caregen.com

Sofwave
Sofwave™ effectively utilizes synchronous ultra-
sound parallel beam (SUPERB™) technology, Molded Levo Max Threads
ensuring minimal downtime during a single 30 Molded Levo Max threads are bi-directional and barbed. They are engineered
to 45-minute session, regardless of skin type. specifically for contouring the lower face, jawline and general submentum area.
FDA-cleared and clinically validated, Sofwave When combined with our Smuth™ threads and our Levo Lock™, the Molded Levo
remodels collagen and stimulates hyaluronic Max threads contribute to a comprehensive facial rejuvenation procedure that can
acid (HA) production, leading to enhancements in be performed in-office in under an hour. PDO Max’s Molded Levo Max threads grab
facial lines, wrinkles, acne scarring appearance, submental fat and reposition it along the natural contours created by a patient’s
cellulite and elevating the eyebrows, submental bone structure. This effectively turns back the closagging, revising the neck, ele-
and neck regions. vating jowls and restoring that chiselled silhouette associated with youth and vigor.

Sofwave: (855) SOFWAVE (763-9283) or visit

PDO Max: (800) 670-0225 or visit www.pdomax.com
www.sofwave.com

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 119

 AnteAGE Eye
AnteAGE® Eye is a powerful yet gentle solution designed to target the signs of aging
in the delicate eye area. Powered by bone marrow stem cell cytokines and loaded
with antioxidants and peptides, this silky, rapidly penetrating formula helps to improve
BIOJUVE
the appearance of lines, puffiness and under-eye darkness – all while defending the
BIOJUVE™ is a living microbe technology for
eye tissue against free radicals. Deeply hydrate, crepiness and truly see the differ-
skin biome care. The Xycrobe™ technology
ence with this one of a kind eye serum.
within BIOJUVE contains a specific strain of
a skin native bacteria, C. acnes defendens.
AnteAGE MD: (877) 350-6350 or visit www.AnteAGE.com These microbes live on the skin surface and
deep within the hair follicles and naturally
produce important Bioessentials™ 24/7 to help
optimize skin health and rebalance the skin
biome. Bioessentials are proteins, fatty acids,
Observ Skin Analysis System
polypeptides and antioxidants that help to
The Observ® imaging system is compatible with the iPad Pro
support a healthy skin environment, fight oxida-
and facilitates the following nine different light modes such as
tive stressors, promote proper skin hydration,
daylight, true UV, woods, cross polarised, parallel polarised,
calm the skin, decrease the appearance of
surface texture, pigmentation, vascularity and 360 light. The
erythema and help to balance sebum produc-
package is fully accessorized. Among other items a table
tion. BIOJUVE is clinically proven to create
stand, light shade, iPad visor and chin rest are included. A
significant improvements in the appearance of
quick reference guide is added that explains the light modes
texture, tone, pore size, fine lines, wrinkles and
and the interpretations thereof.
photodamage in as little as one week*.

Sylton, Inc.: (734) 506-6052 or visit www.sylton.com Crown Aesthetics: (888) 372-3982 or visit
www.crownaesthetics.com

Plexr
Plexr is an advanced non-invasive device that uses plasma innovation
to provide state-of-the-art treatments and satisfactory clinical results.
Plexr Plus offers a comprehensive range of modalities, including
non-ablative, semi-ablative and ablative, enabling you to choose the
modality that best matches the skin’s characteristics and needs.

Med Results: (310) 707-3223 or visit www.med-results.com

AGNES
AGNES is an innovative radiofrequency (RF)
microneedling device focused on selective
electrocoagulation to rejuvenate facial skin and
Viola Threads
sculpt fat. Pioneered by a group of renowned
Viola Threads (FDA 510k cleared #K190264)
dermatologists, the AGNES device utilizes
offers an extensive catalogue of PDO threads
exclusive square wave RF energy, harnessing
and more, including our signature thread PDO
1 MHz of energy output, to focus on gentle yet
Doublelyft Flat Mesh and the newly-released 5D
effective procedures while ensuring patient
Fix Coglyft, a 360-degree multi-cog type thread.
safety. AGNES features exclusive single and
These threads provide full face, neck and body
three-pin needles designed for specific skin
enhancement with lifting and anchoring capa-
concerns and regions, which allows for com-
bilities that can improve even heavy, sagging skin
plete versatility in treatment options for both
tissue because of their large cog size and USP.
patients and providers.

AGNES Medical: (844) 811-1154 or

Viola Threads: (213) 351-0001 or visit www.violathreads.com
visit us.agnesmedical.com

120 The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com

 NCPR
NCPR is a nourishing and revitalizing complex that works on the surface and in
the deeper layers of the extracellular epidermis. It has powerful rejuvenating
effect with immediate hydration action, improving elasticity, firmness, tone and
overall appearance of the skin. Indicated for bio revitalization, collagen stimula-
tion, wrinkle reduction, reducing signs of aging, deep hydration and cells nutri-
tion. It has hyaluronic acid which enhances skin hydration and strengthens its
protective barrier, reducing agents that halt oxidative damage in dermal and
epidermal cells, vitamins C, E and A and B, amino acids with reparative proper-
ties, coenzymes that revitalize and encourage cell proliferation, minerals that
shield the skin from environmental aggressors and rebalance its optimal state.

PlaDuo Toskani US: (954) 804-8195 or visit www.toskani.us

PlaDuo is a laser treatment device that generates
plasma energy and triggers a chemical reaction
in the skin. PlaDuo converts nitrogen gas into
plasma and delivers it to the skin, resulting in Beautiful Skin Superfluid Broad Spectrum SPF30
the production of ROS and RNS which helps to Luminizing skin perfection, coupled with sophisticated protection.
regenerate skin, reduce inflammation and control RATIONALE Beautiful Skin Superfluid Broad Spectrum SPF30 is offered
sebaceous glands. In addition, it is very effective in six universally skin-adapting tints, imbuing a sheer, skin-syncing
in killing bacteria on the surface of the skin and finish. Created with 16.9% zinc oxide, melanin, sodium potassium alu-
treating inflammation caused by bacteria. With minium silicate, iron oxides, vitamin B5, sodium hyaluronate, vitamin E,
no anesthesia and downtime, PlaDuo can ben- bisabolol, amino acids and water lily extract, it calms the appearance
efit people with all skin types without affecting of redness and reanimates the skin’s inherent radiance, for a hyper-
chromophore. natural, incandescent glow.

Cartessa: (877) 662-2783 or

RATIONALE: (424) 430-6698 or visit www.RATIONALE.com
visit www.cartessaesthetics.com

LifeViz
Our full range of 3D LifeViz® systems allows you
to digitalize your consultations and communicate
more effectively with your patients through 3D
images. Portable and compact by design, each of
our cameras achieve remarkable results for face,
body and breast. For a premium approach to opti-
mizing your daily workflow, generating outstanding
before and after images in 3D, look no further than
the LifeViz Pro range. It is designed to let you focus
on what really matters – your patients.

QuantifiCare, Inc.: (888) 678-4450 or visit www.quantificare.com

MG-EXO-SKIN
Utilizing one of the most exciting emerging
technologies – exosomes – MG-EXO-SKIN™
is a regenerative, biomimetic and multipotent
meso-glide that removes the complications of
autologous procedures. Extracted from ethically
The Aesthetic Needle sourced mesenchymal stem cells, exosomes
The Aesthetic Needle 32G x 13 mm (32G x 1/2”)
used in MG-EXO-SKIN come from the youngest
100/box #32G59875 box contains 100 dispos-
and purest source. When paired with EXO-
able premium sterile hypodermic needles with an
SKIN™, one of the first available at-home topical
individually sealed cap. They are made of surgical
non-negotiable solutions containing exosomes,
stainless steel with a polypropylene hub that are
MG-EXO-SKIN™ delivers truly unprecedented
suitable for different needs. It is a convenient uni-
results without additional time spent on pro-
versal fit created for single use only.
cessing and preparation.

Dp Derm: (305) 552-0550 or

Merit Pharmaceuticals: (800) 69-MERIT / (800) 696-3748 or visit www.meritpharm.com
visit www.dpderm.com

The Aesthetic Guide | January/February 2024 | www.theaestheticguide.com 121

 New Feature!

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[email protected] 305-552-0550 dpderm.com