Jyoti Nivas College Autonomous

Hosur Road, Bangalore – 560095

Department of Chemistry
VI Semester B.Sc. Syllabus
Paper VII: Advanced Inorganic and Organic Chemistry II
60 Hours
Unit I 15 Hours
Chapter 1: Industrial materials I 5 Hours
Refractories: Definition. Properties of a good refractory, classification, determination of PCE
values. Abrasives: Definition and classification with examples, applications, hardness-definition and
magnitude of hardness, manufacture and importance of carborundum and tungsten carbide. Glass:
Properties, types, manufacture of soda glass. Composition and applications of borosilicate, metallic
glass, optical and polycarbonate glass, safety glass, fire and bulletproof glasses. Ceramics: Raw
materials and their roles, varieties of clay, production of ceramic ware, glazing, ceramic insulators.
Cement: Raw materials, manufacture of Portland cement (by wet process), setting of cement, role of
water and gypsum.
Chapter 2: Industrial materials II 5 Hours
Paints and Varnishes: Constituents of oil and emulsion paints and their role. Constituents of varnishes.
Fuels: Characteristics, calorific value - definition and its determination using bomb calorimeter.
Coal – varieties. Gaseous fuels- advantages, constituents and their significance. Production of Coal
gas. Composition of LPG. Octane number definition and significance. Explosives: Classification,
preparation of dynamite and TNT. Propellants: Characteristics, classification and their applications.
Chapter 3: Pharmaceutical Chemistry 3 hours
Chemotherapy. Drugs: classification of drugs (i) drugs used for the treatment of diseases due to
infection (antimalarial, sulpha drugs, antibiotics and antiseptic drugs with examples) (ii) drugs used
for the treatment of diseases not due to infection (antipyretics, analgesics, anesthetics, tranquilisers and
hypnotics, narcotics, anticonvulsants, cardiac or cardiovascular and diuretics drugs with examples).
Synthesis of (i) aspirin (from phenol), (ii), paracetamol (from phenol), (iii) chlorophenaramine, (iv)
sulphanilamide (from acetanilide). Structure and uses of (i) Penicillin and (ii) cephalosporin.
Chapter 4: Green Chemistry 2 Hours
Introduction. Principles of Green chemistry with examples - special emphasis on atom economy,
reducing toxicity and green solvents. Green chemistry and catalysis (taking the synthesis of ibuprofen
as an example).

Unit II 15 hours
Chapter 5: Chemistry of Materials 11 Hours
5.1: Nanomaterials
Introduction - nanostructures – types with examples. Propeties - size, shape, specific surface area,
crystallinity, solubility and surface morphology; special properties attributed to materials with nano-
size. Preparation of gold and silver nanoparticles, definition and synthesis methods of self-assembled
nanostructures. Carbon nanotubes and inorganic nanowires. Quantum dots – quantum confinement.
5.2: Conducting polymers
Introduction, definition and examples- polyaniline, polyacetylene. Mechanism of conduction.
Qualitative treatment of doping. Properties: elasticity with high electrical conductivities. Engineering
and biological applications.
5.3: Superconductors
Introduction, definition, type-I, type-II and atypical. Preparation of high-temperature superconductor-
Y1Ba2Cu3Ox±δ. BCS theory (qualitative treatment only) and general applications of high-temperature
superconductors.
Self-study: Fullerenes: Introduction, definition, preparation and isolation of C60. Structure and
chemical reactions (redox reactions, electrophilic aromatic substitution and bromination) of C60.
Commercial uses of C60.
Chapter 6: Water Analysis and Technology 4 Hours
Dissolved oxygen - importance, effect of temperature and determination by Winkler’s method.
Biochemical oxygen demand - defintition, imporatance and permissible limits, prodecure for
determination using DO values. Chemical oxygen demand - defintion, permissible limits for drinking
water and industrial effluents, determiantion using KMnO4 Water Purification technology: Reverse
osmosis and UV filtration.

Unit III 15 Hours

Chapter 7: Aldehydes and Ketones 6 Hours
Review: Nomenclature of carbonyl compounds, nucleophlic addition across C=O, relative reactivity
of aldehydes and ketones toeards nucleophilic addition.
Addition reactions - acetal formation with mechanism. Condensation reactions - acidity of alpha
hydrogen, aldol reaction with mechanism, reaction with ammonia and its derivatives to form
imine, oxime, hydrozone, phenyl hydrazone and semicarbazide, Claisen, Knovenegel and Benzoin
condensation. Disproporationation reaction - Cannizarro reaction with mechanism. Reduction
reactions - reduction by NaBH4, LiAlH4, Wolff-kischener and Clemmenson reductions.
Chapter 8: Carboxylic Acids and thier Derivatives 9 Hours
Review: Nomenclature of di- and tri-carboxylic acids.
8.1: Carboxylic acids
Action of heat on dicarboxylic acids - OMSGAP acids. Hydroxy acids Reactions of tartaric acid and
citric acid – (i) action of heat and (ii) reduction with HI.
8.2: Derivatives of carboxylic acids
Reactions of acid chlorides - hydrolysis, reaction with alcohol, ammonia and lithium dialkyl cuprates.
Reactions of acid anhydrides - hydrolysis, reaction with alcohol, ammonia. Reactions of amides -
hydrolysis, reduction. Reactions of esters - alkaline hydrolysis, ammonolysis and alcoholysis. Relative
reactivity of derivatives.
8.3: Mechanisms of ester hydrolysis
Acid and base catalysed (acyl O-cleavage: BAC2, AAC2; alkyl O-cleavage: AAL1 mechanisms).
Unit IV 15 Hours
Chapter 9: Tautomerism and Enolates 8 Hours
Tautomerism in carbonyl compounds – keto-enol tautomerism; oxime-nitroso tautomerism. Acidity
of α-hydrogen atoms in aldehydes, ketones, and active methylene compounds (diethyl malonate,
ethyl acetoacetate, and acetylacetone). Preparation of diethyl malonate from acetic acid and synthetic
applications of diethyl malonate (preparation of monocarboxylic acids - butanoic acid, dicarboxylic
acid - adipic acid, unsaturated acids: cinnamic- and crotonic- acids; ketones - butanone, cyclic
compounds - barbituric acid). Preparation of ethyl acetoacetate (from ethyl acetate). Synthetic
applications of ethyl acetoacetate (preparation of monocarboxylic acids - butanoic acid; dicarboxylic
acid - succinic acid, unsaturated acids- crotonic acid and cinnamic acid, ketones - butanone).
Chapter 10: Rearrangements 7 Hours
Mechanisms of: Wagner - Meerwein, Fries, Beckmann, Hoffmann, benzil - benzilic acid, Favorskii
rearrangements and Baeyer - Villiger oxidation.
Recommended Books
1. Heaton C. A., An Introduction to Industrial Chemistry, Springer Science and Business Media,
1996.
2. Vandana M, A text book of Industrial Chemistry, Educational Publisher and Distributor, 2017.
3. Sharma B. K., Industrial Chemistry Part-1, Krishna Prakashan, 2023.
4. Felder R. M., Rosseau R. W., Elementary Principles of Chemical processes, Wiley Publishers,
New Delhi.
5. Kingery W. D., Bowen H. K., Uhlmann D. R., Introduction to Ceramics, Wiley publishers, New
Delhi.
6. Geoffrey A. O, Andre C. A, Ludovico C, Chad A. M, Nano chemistry: A Chemical Approach to
Nanomaterials, 2nd edition, Royal Society of Chemistry, 2003.
7. Charles P. P, Frank J O, Introduction to Nanotechnology, Wiley-Interscience, 2008.
8. Pradeep T., Text book of Nanoscience and Nanotechnology, McGraw Hill Education, 2017.
9. Poore, C.P. & Owens, F.J. Introduction to Nanotechnology John Wiley & sons, 2003.
10. Ahluwalia V K, Green Chemistry: Environmetally Benign Reactions, 3rd Edition, Springer. 2021
11. Carey F A, Sundberg R J, Advanced Organic Chemistry, Part A: Structure and mechanisms, 5th
Edition, Springer (India) Pvt Ltd. New Delhi, 2007.
12. Carey F A, Sundberg R J, Advanced Organic Chemistry, Part B: Structure and Mechanisms, 5th
Edition, Springer (India) Pvt Ltd. New Delhi, 2007.
13. Finar, I.L. Organic Chemistry (Vol. I & II), E.L.B.S. • Morrison, R.T. & Boyd, R.N. Organic
Chemistry, Pearson, 2010.
14. Graham Solomon, T.W., Fryhle, C.B. & Dnyder, S.A. Organic Chemistry, John Wiley & Sons,
2014.
15. McMurry, J.E. Fundamentals of Organic Chemistry, 7th Ed. Cengage Learning India Edition,
2013.
16. Sykes, P. A Guidebook to Mechanism in Organic Chemistry, Orient Longman, New Delhi, 1988.
17. Nasipuri D, Stereochemistry of Carbon Compounds, 2nd Edition, New-Age International
Publishers, New Delhi, 1996.
18. Bruckner R, Organic Mechanisms - Reactions, Stereochemistry and Synthesis, SpringerVerlag,
Berlin, Heidelberg, 2010.
19. Clayden J, Greeves N, and Warren S, Organic Chemistry, 2nd Edition, Oxford University Press,
New York, 2012.
20. Smith M B, and March J, March’s Advanced Organic Chemistry, 6th Edition, John-Wiley and
Sons, New York, 2007.
21. Understanding Organic Reaction Mechanisms A. Jacobs, Cambridge Univ Press, 1998.
22. Organic Chemistry M. K. Jain, Nagin & Co., 1987.
23. A Guide to Mechanism in Organic Chemistry P. Sykes, Orient Longman, 2005.
Chemistry Practical Paper VII: Advanced Inorganic and
Organic Chemistry II
Part A: Inorganic Chemistry
1. Titrimetric estimation of Zinc by EDTA.
2. Titrimetric estimation of Nickel by EDTA.
3. Titrimetric estimation of Calcium in limestone.
4. Titrimetric estimation of Copper in brass.
5. Titrimetric estimation of Iron in Haematite.
6. Titrimetric estimation of Ca and Mg in Dolomite.
7. Titrimetric estimation of Cu in a mixture of Ni and Cu.
8. Gravimetric estimation of Ni in a mixture of Ni and Cu.

Part B: Organic Chemistry

1. Cannizarro Reaction – preparation of benzoic acid from benzaldehyde
2. Sandemayer Reaction – preparation of 4-chlorotoluene from 4-toluidine
3. Titrimetric estimation of amino acids
4. Estimation of glucose by Fehling’s method
5. Saponification value of oil
6. Iodine value of oil by Chloramine T method
7. Estimation of keto group
8. Estimation of phenol