Respiratory System hand 4-Pharmacoloay: 1-Bronchospasm of acute symptoms of asthma is irreversible a)True b) False 2-Airway remodeling can be prevented by or fully responsive to currently available treatments a)True b) False 3-Which is True about determination of the causative allergens a) Careful history taking b) Skin prick test c) RAST testing for specific IgE d) All of the above 4- If avoidance of the causative allergen is impossible; Allergen specific immunotherapy is beneficial to induce tolerance a)True 5- Controller medications used for long term control of asthma through a) bronchodilatation b) anti-inflammatory effect 6- All of the following including Long- term control medications Except a) Glucocorticosteroids Sa7wa Scientific Team b) Sustained release Theophylline c) Anticholinergic d) cromones 7-Which is False about Reliever Medication a) relief of bronchoconstriction b) anti-inflammatory effect c) Inhaled long-acting B2 agonists d) anticholinergic drugs e) b&e 8-Concerning to Side effect of Sympathomimetic Non-Selective agonists which is False a) Hypertension b) Hyperglycemia c) Hyperkalemia d) Hypokalemia 9-All of the following is Short acting B2 agonists Except a) Terbutaline b) levalbuterol c) Salmeterol d) Salbutamol 10- Regular use of.......... caused diminution in control of asthma a)Salbutamol b) Pirbuterol Hy LY) a 5 pee pl CamSeanner - Lis d>gusallRespiratory System ©) fenoterol d) formoterol 11-The long term use of SABAs may induce ..... a)Cardiac arrhythmia b) myocardial infarction c) hypokalemia d) tachyphylaxis e)c&d 12-Oral administration is more effective & faster onset than inhaled route a)True b) False 13- The onset of action of Salmeterol is similar to SABAs (5 min) a)True b) False 14-LABAs are used in all of the following Except a) Nocturnal asthma b) with ICSs to prevent symptoms of moderate to severe persistent asthma c) prevent EIB d) monotherapy for long term control of asthma 15- All of the following is Oral LABAs Except a)Salbutamol ‘Sa7wa Scientific Team 37 i b) Salmetrol c) terbutaline d) bambiterol 16-Increasing Theophylline plasma level above ....... 1g/ml produces arrhythmia a) b) 10 c) 20 17- All of the following increase theophylline plasma level Except a)Rapid IV b) Liver disease ©) febril illness d) heart failure 18- using theophylline with erythromycin decrease plasma level a)True b) False 19) the drug of choice for treatment of tuberculosis: a) isoniazid b) refampin c) ethambutol d) pyrazinamide 20) Isoniazid has no side effects on : a) CNS b) liver c) stomach Hy) a 5 ga Bl CamSeanner + Lis d>gusallRespiratory System d) eye 21) Which drug of the following doesn't enter the CSF: a)rifampin b) isoniazid c) ethambutol d) non of the above 22) the drug of choise for chemoprophylaxis against meningitis is: a) isoniazid b) rifampin c) ethambutol d) streptomycin 23) one of the following doesn’t cause vomiting as side effect: a) isoniazid b) ethambutol c) rifampin d) pyrozinamide 24) hyperuricemia is a side effect of : a) refampin b) isoniazid c) ethambutol d) pyrezinamide 25) one drug of the following speeds the inactivation of the warfarin a) ethambutol b) refampin ¢) isoniazid ‘Sa7wa Scientific Team d) pyrazinamide 26) one of the following isn’t a side effect of rifampin : a) flu syndrome b) proteinuria c) hepatitis d) optic neuritis 27) which drug of the following elevates the plasma uric acid : a) refampin b) isoniazid ) ethabutol d) streptomycin 28) which drug of the following cause optic neuritis : a) isoniazid b) refampin c) athambutol d) (a&c) e) all the above 29) Whooping cough is associated with : a)headache b)vomiting c)myopathy d)diarrhea 30) bordetella are : a)motile b)aerobes c)non capsulated d)gram+ 38 By pat) Gul = bya by CamSeanner + Lis d>gusallRespiratory Systen 31) the most important virulent factor of bordetella is: a)pertussis toxin bjtracheal cytotoxin ¢)dermonecrotic toxin djall the above 32) bordetella are transmitted by : a)vector transmission b)transplacental transmission c)droplet transmission d)dust nuclei . Is the least efficient method to obtain bordetella . a)nasopharyngeal swab b)pernasal swab c)cough plate 4d) nasal saline wash 34) For bordetella , in catarrhal stage swans 1S given prophylactically a)penicillin bjerythromycin c)DPT vaccine d)vancomycin 35) legionella pneumophila are.. a) gram + short rods B) gram — long rods c) gram + long rods d) gram — short rods ‘Sa7wa Scientific Team scion id 36). .. is the treatment of choice of legionella pneumophila. a) vancomycin b) ampicillin c) erythromycin d) naficillin 37) For bordetella vaccines... IS used for children under the age of 6 years . ajinfluenza conjugate vaccine b) merthiolate killed vaccine with DPT c) acellular vaccine d) non of the above 38) specimens of legionella pneumophila are cultured on .. a) blood agar b) chocolate agar c) BCYE staining 4d) zeihl neelsen stain 39) catracts is an adverse effect of : a) ICss b) systemic steroids c) cromones d) LTRAs 40) ..nnnsn are the most effective long term therapy available for mild miderate or severe persistent asthma a) ICSs b) systemic steroids Ay Gb Bye Bl CamSeanner + Lis d>gusallRespiratory System c) cromones d) LTRAs 41). Icss. a) cataracts b) hypertension an advers effect of c) hoarseness of voice d) muscle weakness 42) dermal thinning & growth suppression are adverse effects for : a) ICss b) systemic steroids ¢) cromones d) a&b 43) suse appear to involve the chloride channels . a) ICSs b) systemic steroids ©) cromones d) LTRAs 44). inhalation . a) ICSs b) systemic steroids . are administered only by c) cromones d) LTRAs 45) we use to prevent formation of leukotrienes trough inhibition of the enzyme 5- Sa7wa Scientific Team lipoxygenase: a) zileuton b) montelukast c) prantukast d) omalizumab 46) the liver can be affected by using : a) zileuton b) montelukast c) pranlukast d) all the above 47). warfarin . a) zileuton inhibits the metabolism of b) montelukast c) pranlukast d) omalizumab decreases FCERI n on basophils & airway submucosal cells . a) zileuton b) montelukast ©) pranlukast d) omalizumab 49) which of the following is Pharmacotherapy of allergic disease a) Environmental control b) Mediators antagonists c) Immunotherapy d) Prevent mediators release By) a gee Bye GamScanner + li55 &guusallRespiratory System e) b&d 50) Corticosteroids can Prevent mediators release only a) True b) False 51) Regarding to the action of mediators of anaphylaxis which is False a) Spasmogenic b) Stimulate sensory nerve endings c) Hypertension d) inducers of chronic inflammation 52) Which mediators generated during Ag-Ab reaction from phospholipid of mast cells wall a) Histamine b) Heparin c) PAF d) chondroitin sulphates 53) A 4-year-old child has atopic dermatitis due to severe allergies to dust, animal dander, and many kinds of pollens. Mediators released from which cell type are responsible for the clinical manifestations immediately following exposure to these substances? a) Bcells b) Macrophages c) Mast cells d) Thi cells e) Th2 cells Sa7wa Scientific Team 41 be wrend 54) Which of the following inhibits kinin degradation a) codeine b) Aspirin c) captopril d) morphine 55) Regarding to criteria of drug allergy which is False a) the reaction doesn't occur on initial exposure b) the reaction is dose dependent c) the reaction occurs in small % of pateints d) blood eosinophilia is suggestive 56) which drugs of anti-histamines have low therapeutic index a) Loratadine b) cetirizine c) Chlorpheniramine d) All of the above 57) the combination of sedating anti- histamines with a adrenoreceptors agoinst improve their therapeutic effect a) True b) False 58) Which of the following is True about DSCG in allergic rhinitis a) safe b) minimal side effect HS cab 5 ga 5 CamScanner 2 55 & guallRespiratory System c) has short action duration d) administered up to 6 times daily e) All of the above 59) Which of the following is not a feature of allergic rhinitis? a) Sneezing b) Rhinorthoea. ¢) Itching of the nose d) Nasal blockage. e) Facial pain or pressure 60) Rhinitis medicamentosa or rebound rhinitis is due to the prolonged use of: a) Sodium cromoglycate. b) Corticosteroids. c) Antihistamines. d) Oxymetazoline. e) Anti-cholinergics. 61) In allergic rhinitis, ipratropium bromide is effective in controlling: a) Nasal blockage. b) Sneezing. ¢) Itching of the nose. d) Rhinorrhoea. e) None of the above 62) which drug is choosed in acute urticarie a) Adrenaline b) Hydroxyzine ¢) Prednisone d) Doxepin e) a&b 63) In Urticaria treatment , inhibit degranulation of mast cell a) Adrenaline b) Ephidrine ©) Terbutaline d) All of the above 64) Which is the 1* line for treatment anaphylaxis a) IV fluid & vasopressin b) IV aminophylline ¢) Adrenaline d) Non of the above 4-Pharmacology answe: 3D 5-B 4A 6-C ‘Sa7wa Scientific Team WY Gb — Spee CamScanner 2 Li3.d d>suuaall7-E 8-C 9-C 10-C 11-E 12-B 13-B 14-D 15-B 16-C 17-c 18-B 19-B 20-C 21-D 22-B 23-A Respiratory System Sa7wa Scientific Team 25-B 26-D 27-C 28-D 29-B 30-B 31-D 32-C 33-C 34-B 35-D 36-C 37-B 38-C 39-B 40-A 41-C 42-D 43-C 44-C 45-A 46-D 47-A 48-D 49-E 50-B 51-C 52-C 53-C 54-C 55-B 56-C 57-B 58-E Doar 60-D 61-D '62=E 63-C CamScanner 2 li9. d>suuaall ASSN a Spe Bl