FMGE NEET PG INICET USMLE PLAB
One Liners to Remember
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Biochemistry One Liners
Hartnup disease is due to defective transport of -
Tryptophan.
Hunter syndrome is due to deficiency of - Iduronate
Sulfatase.
Enzyme-deficient in Tay Sach’s disease is -
Hexosaminidase A
The earliest symptom of Tay Sach’s disease is -
Exaggerated startle response.
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Biochemistry One Liners
Accumulation of Homogentisic acid causes Ochronosis.
The precursor of Adrenaline and Noradrenaline is -
Tyrosine.
Norepinephrine to epinephrine conversion requires enzyme
- Phenylethanolamine N methyltransferase.
Enzyme deficiency in McArdle’s disease is - Muscle
Phosphorylase Deficiency.
Galactosemia is due to the deficiency of - Galactose 1
Phosphate Uridyltransferase.
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Serotonin is also known as - 5 Hydroxy Tryptamine.
HIAA is secreted in Urine in - Carcinoid
A most sensitive method for glucose estimation is -
Glucose Oxidase Method.
Substrate level phosphorylation in the TCA cycle is in step
- Succinate thiokinase.
Lactose produced by glycolysis is used by - Cori cycle &
TCA cycle.
Number of ATP produced per turn of the TCA cycle is - 10.
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Muscle glycogen stores cannot be used to provide
glucose into the circulation because of lack of - Glucose 6
Phosphatase.
Hormone-sensitive lipase is inhibited by Insulin.
Arachidonic Acid is synthesised from - Linoleic Acid.
Fatty liver is due to the accumulation of Triglycerides.
Acetoacetate is the primary ketone body.
Niemann Pick Disease is due to deficiency of enzyme -
Sphingomyelinase.
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Alpha oxidation of fatty acids takes place - Peroxisomes.
The urea cycle is linked to Kreb’s cycle by Fumarate.
Brain utilises urea in the form of Glutamine.
Boiled cabbage or rancid butter smelling urine is seen in-
Tyrosinemia.
Source of norepinephrine is - Tyrosine
The end product of purine metabolism is - Uric Acid.
Amino acid used in Carnitine synthesis is - Lysine.
Hormone synthesised from Tyrosine is Thyroxine.
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Biochemistry One Liners
Amino acid involved in urea synthesis is Aspartic acid.
Enzyme defect in Krabbe’s Diseases is BetaGalactosidase.
Enzyme-deficient in Hers Disease is - Liver Phosphorylase.
Folding & unfolding of DNA is done by Topoisomerases.
LDL reuptake in the liver is associated with - Apo B100 &
Apo E.
Micro RNA is gene silencing RNA.
Vitamin B12 is absorbed in - Ileum.
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Insulin secretion is associated with Zinc.
Activated Pantothenic acid found in Coenzyme A.
Absorption of iron is increased by - Vitamin C.
The site at which 1,25 hydroxylation of Vitamin D takes
place in the kidneys is Proximal convoluted tubules.
Test to diagnose Thiamine deficiency is - RBC
Transketolase.
Haemoglobin synthesis starts with - Glycine.
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Embryonic Hemoglobin is Alpha 2, epsilon 2.
The major role of 2,3 BPG in RBC is - Release of oxygen.
Hemolysis on oxidation is seen in - G6PD Deficiency.
Iron in haemoglobin binds with - Histidine
Chylomicrons core is formed by - Triglycerides &
Cholesterol.
Inheritance of Familial Hypercholesterolemia is -
Autosomal dominant.
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Principle apoprotein in Chylomicrons is Apo B 48.
Carrier of cholesterol is - LDL.
Maximum electrophoretic mobility and least LIPID content
is - HDL.
Insulin-stimulated glucose uptake is by - GLUT4.
The normal renal threshold for glucose excretion is -
180gm%.
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Biochemistry One Liners
Rate limiting enzymes:
➔ Cholesterol synthesis - HMG CoA reductase.
➔ Ketone body synthesis - HMG CoA synthase.
➔ Krebs cycle - Isocitrate dehydrogenase.
➔ Catecholamine synthesis - Tyrosine hydroxylase.
➔ Glycolysis - Phosphofructokinase.
➔ Gluconeogenesis - Pyruvate carboxylase.
➔ Bile acid synthesis - 7 alpha hydroxylase.
➔ Fatty acid synthesis - Acetyl CoA carboxylase.
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Disclaimer:
This information is not intended as a substitute for
professional medical advice, emergency treatment or
formal first-aid training. Don't use this information to
diagnose or develop a treatment plan for a health problem
or disease without consulting a qualified health care
provider. If you're in a life-threatening or emergency
medical situation, seek medical assistance immediately.
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