Drug Study
Drug Study
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
Generic Name of Drug:
Losartan
Therapeutic Class: Antihypertensive
Drug Action/s:
Blocks vasoconstricting and aldosterone-secreting effects of angiotensin II at various receptor sites,
including vascular smooth muscle and adrenal glands. Also increases urinary flow and enhances
excretion of chloride, magnesium, calcium, and phosphate. Therapeutic Effect: Causes vasodilation,
decreases peripheral resistance, decreases B/P.
Dose, frequency, and route of administration (doctor’s order):
50 mg/ PO BID
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV).
Indication/s (reason/s) for administering the medication to the patient:
Treatment of hypertension in adults and children 6 yrs and older. Used alone or in combination with
other antihypertensives. Treatment of diabetic nephropathy with an elevated creatinine and proteinuria
(in pts with type 2 diabetes and history of hypertension), prevention of stroke in pts with hypertension
and left ventricular hypertrophy. OFF-LABEL: Slow rate of progression of aortic root dilation in
children with Marfan’s syndrome. HF in pts intolerant of ACE inhibitors
Treatment of hypertension in adults and children 6 yrs and older. Used alone or in combination with
other antihypertensives. Treatment of diabetic nephropathy with an elevated creatinine and proteinuria
(in pts with type 2 diabetes and history of hypertension), prevention of stroke in pts with hypertension
and left ventricular hypertrophy. OFF-LABEL: Slow rate of progression of aortic root dilation in
children with Marfan’s syndrome. HF in pts intolerant of ACE inhibitors
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
Dizziness Hypotension
Upper respiratory tract infection Tachycardia
List important nursing responsibilities you have to consider when administering the medication:
List important nursing responsibilities you have to consider when administering the medication:
Obtain B/P, apical pulse immediately before each dose, in addition to regular monitoring (be
alert to fluctuations).
Assess medication history (esp. diuretics).
Monitor vital signs closely.
Monitor for signs and symptoms of overdose (such as confusion, hypotension, coma, and
labored breathing).
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
Patient health teachings in relation to the medication:
Report any sign of infection (sore throat, fever), chest pain.
Do not take OTC cold preparations, nasal decongestants.
Limit salt intake.
Tell patient and family about drug’s possible CNS effects. Recommend appropriate safety
precautions.
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
Generic Name of Drug:
Tramadol
Therapeutic Class: Analgesic
Drug Action/s:
Binds to mu-opioid receptors in CNS, inhibiting ascending pain pathway. Inhibits reuptake of
norepinephrine, serotonin, inhibiting descending pain pathways. Therapeutic Effect: Reduces pain.
Dose, frequency, and route of administration (doctor’s order):
50 mg/ IV q8h
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV).
Indication/s (reason/s) for administering the medication to the patient:
Immediate-Release: Management of moderate to moderately severe pain.
Extended-Release: Around-the-clock management of moderate to moderately severe pain for
extended period.
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
Dizziness Seizures
Vertigo Agitation
List important nursing responsibilities you have to consider when administering the medication:
Monitor pulse, B/P, renal/hepatic function.
Assist with ambulation if dizziness, vertigo occurs. Dry crackers, cola may relieve nausea.
Monitor daily pattern of bowel activity, stool consistency.
Sips of water may relieve dry mouth.
Assess for clinical improvement, record onset of relief of pain.
Patient health teachings in relation to the medication:
Instruct patient to watch for and immediately report signs and symptoms of serotonin
syndrome (shivering and diarrhea, muscle rigidity, fever, and seizures).
Tell patient to immediately report sign and symptoms of allergic reaction (such as itching,
hives, and difficulty breathing, or swelling of face, tongue, or throat).
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
Generic Name of Drug:
Metronidazole
Therapeutic Class: Antibacterial, Antiprotozoal, Amebicidal
Drug Action/s:
Diffuses into organism, interacting with DNA causing a loss of helical DNA structure and strand
breakage, inhibiting protein synthesis. Therapeutic Effect: Produces bactericidal, antiprotozoal,
amebicidal, trichomonacidal effects. Produces anti-inflammatory, immunosuppressive effects when
applied topically.
Dose, frequency, and route of administration (doctor’s order):
500mg/ IV PRN
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV).
Indication/s (reason/s) for administering the medication to the patient:
Treatment of anaerobic infections (skin/skin structure, CNS, lower respiratory tract, bone/joints,
intraabdominal, gynecologic, endocarditis, septicemia). Treatment of H. pylori (part of multidrug
regimen); surgical prophylaxis (colorectal), trichomoniasis, amebiasis. Topical treatment of acne
rosacea or inflammatory lesions.
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
Nausea Numbness
Dry mouth / metallic taste Tingling of hands and feet
List important nursing responsibilities you have to consider when administering the medication:
Monitor I.V. site. Avoid prolonged use of indwelling catheter.
Monitor daily pattern of bowel activity, stool consistency.
Monitor I&O, assess for urinary problems.
Be alert to neurologic symptoms (dizziness, paresthesia of extremities).
Patient health teachings in relation to the medication:
Urine may be deep brownish red.
Inform patient that drug may cause metallic taste.
Advise patient to report fever, sore throat, bleeding, or bruising.
Avoid tasks that require alertness, motor skills until response to drug is established.
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
Generic Name of Drug:
Omeprazole
Therapeutic Class: Proton pump inhibitor
Drug Action/s:
Suppresses gastric secretion by inhibiting hydrogen/potassium ATPase enzyme system in the gastric
parietal cell; characterized as a gastric acid pump inhibitor, since it blocks the final step of acid
production.
Dose, frequency, and route of administration (doctor’s order):
40 mg/ IV BID
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV).
Indication/s (reason/s) for administering the medication to the patient:
Treatment of duodenal and gastric ulcer, NSAID - associated gastric acid and duodenal ulcers or
erosions, Helicobacter pylori eradication in peptic ulcer disease, reflux esophagitis, symptomatic
gastro-esophageal reflux disease, acid related dyspepsia and Zollinger - Ellison syndrome. In this case,
it blocks the production of gastric acid to prevent gastritis that can lead to peptic ulcer and can cause
gastric bleeding.
Since the patient has a jejunostomy tube and can only ingest a small sip of water because he is
restricted to eating foods orally considering his condition, his stomach still produces the digestive
juices or stomach acid that are otherwise used to digest the food that we eat. In such a situation, the acid
from the stomach will start to travel into the esophagus, causing pain, a burning sensation, and
discomfort in her chest and throat. Omeprazole was ordered by the doctor so that the patient would
prevent acid reflux and ulcers, thus preventing pain as well.
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
Dizziness Abdominal pain
Headache Stomach pain
List important nursing responsibilities you have to consider when administering the medication:
Monitor patient for signs and symptoms of acute interstitial nephritis.
Assess for changes in bowel elimination and GI upset to identify possible adverse effects.
Monitor patients for signs and symptoms of low magnesium level, such as abnormal HR or
rhythm, palpitations, muscle spasm, tremors, or seizures.
Patient health teachings in relation to the medication:
Tell the patient to swallow tablets whole and not open, crush, or chew them.
Advice patient to report severe diarrhea; black, tarry stools; abdominal cramps/pain, continuing
headache; product may have to be discontinued.
Teach patient to recognize and report signs and symptoms of low magnesium levels.
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
Drug Action/s:
Inhibits cell-wall synthesis, promoting osmotic instability; usually bactericidal.
Dose, frequency, and route of administration (doctor’s order):
1g IV q8h
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV). Patient have also undergone Exploratory, and Tube Jejunostomy Insertion.
Indication/s (reason/s) for administering the medication to the patient:
Cefoxitin is a semi-synthetic, broad-spectrum antibiotic for parenteral administration used for
the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and
joint infection, and lower respiratory tract infection.
Since the patient had undergone a EL, Tube Jejunostomy procedure, cefoxitin was given as a
perioperative prophylaxis to avoid serious infections of the respiratory or GU tracts; skin, soft-tissue,
bone, or joint infection; bloodstream or intra-abdominal infection caused by susceptible organisms.
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
Nausea Thrombocytopenia
Headache Diarrhea
List important nursing responsibilities you have to consider when administering the medication:
Monitor patient for superinfection or diarrhea and treat appropriately, especially if large doses
are given, therapy is prolonged, or patient is at high risk.
Monitor signs of allergic reactions and anaphylaxis, including pulmonary symptoms (tightness
in the throat and chest, wheezing, cough dyspnea) or skin reactions (rash, pruritus, urticaria).
Notify physician or nursing staff immediately if these reactions occur.
Monitor injection site for pain, swelling, and irritation. Report prolonged or excessive injection-
site reactions to the physician.
Patient health teachings in relation to the medication:
Tell patient to report adverse reactions and signs and symptoms of superinfection promptly.
Instruct patient to report discomfort at IV site.
Advise patient to report loose stools or diarrhea.
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
Generic Name of Drug:
Hyoscine butylbromide
Therapeutic Class: Antispasmodic; Anticholinergic
Drug Action/s:
Hyoscine-N-butyl bromide (HNBB) acts by interfering with the transmission of nerve impulses by
acetylcholine in the parasympathetic nervous system. HNBB exerts a spasmolytic action on the smooth
muscle of the gastrointestinal, biliary, and urinary tracts. As a quaternary ammonium derivative,
hyoscine-N- butyl bromide does not enter the central nervous system. Therefore, anticholinergic side
effects at the central nervous system do not occur. Peripheral anticholinergic effects result from a
ganglion-blocking action within the visceral wall as well as from anti- muscarinic activity.
Dose, frequency, and route of administration (doctor’s order):
10 mg IV q6h
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV). Patient have also undergone Exploratory, and Tube Jejunostomy Insertion.
Indication/s (reason/s) for administering the medication to the patient:
Hyoscine butyl bromide is indicated in acute spasm, as in renal or biliary colic, in radiology for
differential diagnosis of obstruction and to reduce spasm and pain in pyelography, and in other
diagnostic procedures where spasm may be a problem (e.g. gastroduodenal endoscopy).
Since the patient is experiencing gastric pain, HNBB are given or indicated for the relief of spasm of the
genito-urinary tract or gastro- intestinal tract.
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
Constipation Increased ICP
Blurred Vision Tachycardia
List important nursing responsibilities you have to consider when administering the medication:
Raise side rails as a precaution because some patients become temporarily excited or disoriented
and some develop amnesia or become drowsy.
Reorient patient, as needed, Tolerance may develop when therapy is prolonged.
Atropine-like toxicity may cause dose related adverse reactions. Individual tolerance varies
greatly.
Overdose may cause curare-like effects, such as respiratory paralysis. Keep emergency
equipment available.
Patient health teachings in relation to the medication:
HNBB will potentiate the effect of alcohol and other CNS depressants.
Teach patient to not take antacids and antidiarrheal 2 to 3 hours prior to raking this drug.
Teach patient for the adverse reactions of the drug such as Constipation, Blurred feeling, Nausea
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
or vomiting, Lightheadedness, and Headache.
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
Generic Name of Drug:
Metoclopramide
Therapeutic Class: Antiemetic, GI stimulant
Drug Action/s:
Blocks dopamine/serotonin receptors in chemoreceptor trigger zone of the CNS. Enhances
acetylcholine response in upper GI tract, causing increased motility and accelerated gastric emptying
without stimulating gastric, biliary, or pancreatic secretions; increases lower esophageal sphincter tone.
Therapeutic Effect: Accelerates intestinal transit, promotes gastric emptying. Relieves nausea,
vomiting.
Dose, frequency, and route of administration (doctor’s order):
1 amp/ IV q8h
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV). Patient have also undergone Exploratory, and Tube Jejunostomy Insertion.
Indication/s (reason/s) for administering the medication to the patient:
Symptomatic treatment of diabetic gastroparesis, prevent/treat nausea/vomiting with chemotherapy or
after surgery.
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
List important nursing responsibilities you have to consider when administering the medication:
Monitor for anxiety, restlessness, extrapyramidal symptoms (EPS) during IV administration.
Monitor daily pattern of bowel activity, stool consistency.
Assess skin for rash.
Evaluate for therapeutic response from gastroparesis (nausea, vomiting, bloating).
Monitor renal function, B/P, heart rate.
Monitor patient closely for signs and symptoms of neuroleptic malignant syndrome
(hyperthermia, muscle rigidity, altered consciousness, and evidence of autonomic instability
[irregular pulse or blood pressure, tachycardia, diaphoresis, and cardiac arrhythmias]);
immediately discontinue drug if these symptoms occur.
Patient health teachings in relation to the medication:
Avoid tasks that require alertness, motor skills until response to drug is established.
Report involuntary eye, facial, limb movement (extrapyramidal reaction).
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
Generic Name of Drug:
Nicardipine
Therapeutic Class: Antianginal, Antihypertensive
Drug Action/s:
Blocks dopamine/serotonin receptors in chemoreceptor trigger zone of the CNS. Enhances
acetylcholine response in upper GI tract, causing increased motility and accelerated gastric emptying
without stimulating gastric, biliary, or pancreatic secretions; increases lower esophageal sphincter
tone. Therapeutic Effect: Accelerates intestinal transit, promotes gastric emptying. Relieves nausea,
vomiting.
Dose, frequency, and route of administration (doctor’s order):
10g/ 9cc PNSS IV STAT
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV). Patient have also undergone Exploratory, and Tube Jejunostomy Insertion.
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
Generic Name of Drug:
Kaviben
Therapeutic Class: Intravenous Nutritional Periods.
Drug Action/s: The amino acids provide the structural units that make up proteins and are used to
synthesize proteins and other biomolecules or are oxidized to urea and carbon dioxide as a source of
energy. Intravenously administered lipids provide a biologically utilizable source of calories and essential
fatty acids. Fatty acids serve as an important substrate for energy production. The most common
mechanism of action for energy derived from fatty acid metabolism is beta- oxidation
Dose, frequency, and route of administration (doctor’s order):
1400kcal x 24
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV). Patient have also undergone Exploratory, and Tube Jejunostomy Insertion.
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV). Patient have also undergone Exploratory, and Tube Jejunostomy Insertion.
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
Abdominal Pain Haematochezia
Diarrhea Abdominal spasm
List important nursing responsibilities you have to consider when administering the medication:
Evaluate periodically patient's need for continued use of drug; bisacodyl usually produces 1 or 2 soft
formed stools daily.
Monitor patients receiving concomitant anticoagulants. Indiscriminate use of laxatives results in
decreased absorption of vitamin K.
Patient health teachings in relation to the medication:
Add high-fiber foods slowly to regular diet to avoid gas and diarrhea. Adequate fluid intake includes
at least 6–8 glasses
DRUG STUDY
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
Constipation Drowsiness
Headache Sweating
List important nursing responsibilities you have to consider when administering the medication:
Correct hypovolemia prior to administration of ketorolac.
Lab tests: Periodic serum electrolytes and liver functions; urinalysis (for hematuria and proteinuria)
with long-term use.
Monitor urine output in older adults and patients with a history of cardiac decompensation, renal
impairment, heart failure, or liver dysfunction as well as those taking diuretics. Discontinuation of drug
will return urine output to pretreatment level.
Monitor for S&S of GI distress or bleeding including nausea, GI pain, diarrhea, melena, or
hematemesis. GI ulceration with perforation can occur anytime during treatment. Drug decreases
platelet aggregation and thus may prolong bleeding time.
Monitor for fluid retention and edema in patients with a history of CHF.
Patient health teachings in relation to the medication:
Watch for S&S of GI ulceration and bleeding (e.g., bloody emesis, black tarry stools) during long-
term therapy.
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
Note: Possible CNS adverse effects (e.g., light-headedness, dizziness, drowsiness).
Do not use other NSAIDs while taking this drug.
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
300mg, QID, IV
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV). Patient have also undergone Exploratory, and Tube Jejunostomy Insertion.
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
Abdominal Pain Blood Disorder
Vomiting Liver and Kidney disorder
List important nursing responsibilities you have to consider when administering the medication:
Monitor for S&S of: hepatotoxicity, even with moderate acetaminophen doses, especially in
individuals with poor nutrition or who have ingested alcohol over prolonged periods; poisoning,
usually from accidental ingestion or suicide attempts; potential abuse from psychological
dependence (withdrawal has been associated with restless and excited responses
Patient health teachings in relation to the medication:
Do not take other medications (e.g., cold preparations) containing acetaminophen without
medical advice; overdosing and chronic use can cause liver damage and other toxic effects.
Do not self-medicate adults for pain more than 10 days without consulting a physician.
Do not use this medication without medical direction for: fever persisting longer than 3 days,
fever over 39.5° C (103° F), or recurrent fever.
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
4mg, q8 PRN, IV
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV). Patient have also undergone Exploratory, and Tube Jejunostomy Insertion.
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
headache Fatigue
chills constipation
List important nursing responsibilities you have to consider when administering the medication:
Monitor fluid and electrolyte status. Diarrhea, which may cause fluid and electrolyte imbalance,
is a potential adverse effect of the drug.
Monitor cardiovascular status, especially in patients with a history of coronary artery disease.
Rare cases of tachycardia and angina have been reported.
Patient health teachings in relation to the medication:
Be aware that headache requiring an analgesic for relief is a common adverse effect.
St. Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
College of Nursing
2nd Semester, AY 2022-2023
DRUG STUDY
Name: Alfred Gallema
Age: 68 y/o
Sex: Male
Weight: 53 kg
Case/Diagnosis:
Patient’s admitting diagnosis is Indirect Inguinal Hernia and post-operative diagnosis is Gastric Mass
Malignant (Stage IV). Patient have also undergone Exploratory, and Tube Jejunostomy Insertion.
Two (2) most common side-effects of the Two (2) most common adverse effects of the
medication medication
nausea febrile response
diarrhea venous thrombosis
List important nursing responsibilities you have to consider when administering the medication:
Clinical evaluation and periodic laboratory determinations are necessary to monitor changes in
fluid balance, electrolyte concentrations, and acid base balance during prolonged parenteral
therapy or whenever the condition of the patient warrants such evaluation.
Patient health teachings in relation to the medication: