2079/06 [Bachelor Level /BDS/1* Year/TU/IOM Integrated Basic Medical Science ~ Time: 4 hours General Concepts-I-Th. ___ Full Marks: 120 Candidates are required to give their answers in their own words as far as practicable. The figures in the margin indicate full marks. Attempt all the questions. Use separate answer copies for each group. No extra answer sheet will be provided. Group "A" Anatomy- 20 1. Define neuron. Classify neuron with examples. 144-5 2. How does trisomy 21 occur? Explain the clinical features of trisomy21. 243-5 3. Classify cartilage. Mention its general features. Draw a neat labeled diagram of histology of any one type of cartilage. 142+ 4. Write short notes on: 2x2. a. Arterial supply of typical long bone b. Derivatives of surface ectoderm Grou} }" Physioloy 5. Explain the structure of cell membrane with a suitable diagram. List functions of cell membrane proteins. 3+2=5 6. Explain diffusion (simple and facilitated) and osmosis with suitable examples. 3+2=5 7. Write short notes on: 4x2.5=10 Organ-system in human body Refractory period Reflex mechanism Body fluid compartments aege “0m -20 8. Define pharmacokinetics. Describe four processes of pharmacokinetics with suitable examples. 1a 9. Explain the precautions that should be taken in using drugs in patient with hepatic and renal diseases. 10. Defi 16.3) 17.W 18.1 19.1 20.1 ; 2510, Define therapeutic drug monitoring, List the indications and limitations of therapeutic drug monitoring, 11, Write short notes on: a. Drug dependence b, Dose calculation in children 14495 2x2,5=5 12. Discuss factors responsible for delayed wound healing, 4 13. Write down pathogenesis of type I hypersensitivity. 4 14, Write short notes on: 4x3=12 a. Granulomatous inflammation b. Atrophy c. Down's syndrome d. Anaphylactic shock 15, What are isoenzymes? Describe the role of isoenzymes in the diagnoses of various diseases with suitable examples. 1+5=6 16. Sketch the steps of uric acid synthesis. S. 17. Write short notes on: 3x3=9 a. Classification of lij b. Vitamin A c. Polysaccharides Group "F" Microbiology-200 18. Define sterilization. List the methods of sterilization. Explain the use of autoclave. 14+2+2=5, 19. Define normal flora? List down any four normal flora ofFuturis: 120 _| swore Ta thelr own words oup “E” Bice! 15. What are isoenzymes? Deser! the diognoses of various diseases with 6, Sketch the steps of uri acid synthesis: 212-5, 4x2,5°10 21, Describe the contribution of Robert Koch,Group "A" Anatomy- 20 luscles of facial expression and mention the ‘any four muscles. What is Bell's palsy? 2+2+1-5 te between sympathetic and parasympathetic 5 Describe the pathway followed by the corticospinal tract. Enumerate the clinical features due toits lesions. 4+1=5 2x2.5=5 b. Erb’s paralysis Group “B" Physiology ~ 20 Define synapse. Explain the mechanism of synaptic transmission Leas Draw an explanatory diagram of pathway that carries sensation and proprioception from periphery to ther sensations carried by this pathway, 4+1=5 Functional difference between skeletal muscle and. smooth muscle Functions of muscle spindle Functions of external and middle ear ‘wo specific adverse effects.2#2¢ 1-5 odiazepines and rugeeffects. 2424155 4x2.5=10 with selective Opioid dependence Second gas effect Group "D" Pathology ~ 20 ypathogenesis and morphology of 4 1434 4x3=12 Hyperthyroidism Astrocytoma Group "E” Biochemistry ~ 20 14. How is calcium and phosphorous homeostasis s ind classify neurotransmitters. Describe the is and breakdown of acetylcholine. 1423-6 3x39 17, Name any two common bacterial pathogens that infect Central Nervous System (CNS). Describe the pathogenesis, ‘of polio. 19405 18, Describe enzymes produced by Staphylococcus aureus. 19, Write about rabies vaccine, 5 20, Define oncogenic viruses and enlist them. 24385,2a ) aS10ape oytdads Omi 1811 ptre auTeD0pH Jo UoNDe Jo | wisTueYooU! at aquiosag “sBnup onatnsoue [e991 no} sr] “g 0¢ = AB0joowmseyg .D, anor S-o+1 ‘uoIssiusuey E endeuds jo wsrueysou ain uredxa ‘asdeucs auyaq “c ae Oe = RsOTOTSaGaC pue eUyeC “ST osye uresSerp ay} yoI04S ¢paureyuTeus siseysoouoy snoroydsoyd pue WNIOTeO St MOH “pT 0g = Ansjureqoors .a, €norp euroiA20nsy “P wustproscyziedsy “2 snqeydaooxpsyi “q euroursies 1]99 [ese “e aIsexb :Uo S}0U VOUS ALIA “ET b=8t1 -spiuuaut Jo sad yuasayip ur S#urpuy ASO AM “SH! 2 ySw1093S0 Jo ABojoydiour pue sisauedoyyedone ureydxs “1 1 0g = AB0j0MIeE .C, EnoTD yoaye seB puooag “p souspuadap piordg -> ssoqnyut Z-XOO aanoopas YEA sIONqIUUE KOO esuou areduioy “q quexejar afosnur peya[axs Burzurejodag -e O1=S'2xXb 10 SOU LOYS SIM “OT S=14+0+7, sjoajja Btup asiaape pur sasn oyploads sir s1U9 pue sauidazerpozusg jo uonze jo wstueyoou oy UTEIdxy ~6