Chapter 7 - Muscuar System
Chapter 7 - Muscuar System
MUSCULAR SYSTEM
K.A. YATCO
SKELETAL MUSCLE STRUCTURE ● cover the attachment sites on the actin
– CONNECTIVE TISSUE COVERINGS OF MUSCLE myofilaments
(MEMPE) ● located along the grove between the
5.) Epimysium/Muscular fascia ● twisted strands of actin myofilaments
● connective tissue sheath that surrounds a Myosin heads
skeletal muscle [outer] ● resemble golf club heads;
3.) Muscle fasciculi ○ bind to attachment sites
● numerous visible bundles that make up ○ bend and straighten
the muscle ○ break down ATP
4.) Perimysium
● loose connective tissue that surrounds the SACROMERE
muscle fasciculi [each muscle fiber] basic structural and functional unit of skeletal muscle
1.) Muscle fibers Z DISK – network of protein fibers forming an
● several muscle cells that composes a attachment site for actin myofilaments
I BAND – consists of actin myofilaments spans
fasciculus
each Z disk
2.) Endomysium
A BAND – darker
● loose connective tissue that surrounds a – central region that extends the
muscle fiber length of the myosin of myofilaments
H ZONE – second light zone that consists of
MUSCLE FIBER STRUCTURE myosin myofilaments
Sarcolemma M LINE – dark staining bands
● cell membrane of the muscle fiber NOTES:
Transverse tubules (T tubules) – the arrangement of the actin and myosin filaments
in sacromeres gives the myofibrils a banded
● tube-like invaginations w/c occur at appearance.
regular intervals along the muscle fiber
Sarcoplasmic reticulum the alternating I bands and A bands of the
sacromeres are responsible for the striations in
● highly organized smooth E.R. the skeletal muscle fibers.
● has a relatively high concentration of Ca2
+ (muscle contraction)
EXCITABILITY OF MUSCLE FIBERS
Sarcoplasm
Resting membrane potential
● cytoplasm of a muscle fiber
● Cell membranes have a negative charge
Myofibrils
on the inside relative to a positive charge
● threadlike structures composed of:
outside
○ Actin myofilaments - thin
● occurs because there is an uneven
filaments and purple
distribution of ions
○ Myosin Myofilaments - thick
– Concentration of K+ inside the cell CM > outside
filaments and green
the CM
Sarcomere
– Concentration of Na+ outside the CM > inside the
● highly ordered, repeating units of actin +
CM
● myosin myofilament
● joined end to end to form the myofibril
DIFFERENT TYPES OF ION CHANNEL
ACTIN AND MYOSIN MYOFILAMENTS
Nongated/Leak channels
● always open
Troponin molecules
Chemically gated channels
● binding sites for Ca2 +
● closed until a chemical binds
● attached at specific intervals along the
them and stimulates them to open
actin myofilaments
Depolarization
Tropomyosin filaments
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● the inside of the CM membrane comes ● myosin heads attach to the myosin
more positive than the outside of the cell attachment sites on the actin
● Na+ ions move into cells myofilaments
Repolarization
● the change back to the resting membrane Muscle Twitch
Potential ● contraction of a muscle fiber in response
● K+ ions moves out of cells to a stimulus
Action Potentials
● the rapid depolarization and repolarization – Lag/Latent phase
of the CM ● time bet. the application of a stimulus and
● results in muscle contraction the beginning of contraction
– Contraction phase
NERVE SUPPLY ● time during which the muscle contract
Motor neurons – Relaxation phase
● specialized nerve cells that stimulate ● time during which the muscle relaxes
muscles to contract
Neuromuscular junction Summation
● a branch that forms a junction with a ● the force of contraction of an individual
muscle fiber muscle fiber is increased by rapidly
Synapse stimulating them
● a single motor neuron and all the skeletal Tetanus
muscle fibers it innervates ● convulsive tension
Presynaptic terminal ● a sustained contraction that occurs when
● enlarged axon terminal the frequency of stimulus is so rapid that
Synaptic cleft no relaxation occurs
● the space between the presynaptic ○ caused by Ca+ build up in the
terminal and the muscle fiber membrane myofibrils
Postsynaptic membrane Recruitment
● the muscle fiber membrane ● the no. of muscle fibers contraction is
Synaptic vesicles increased by the increasing no. of motor
● presynaptic terminal that contains small units stimulated + muscle contracts with
vesicles more force
Acetylcholine (ACh) Stimulus frequency
● neurotransmitter contained in the Vesicle ● no. of times a motor neuron is stimulated
● a molecule released by a presynaptic per second
nerve cell that stimulates/inhibits a ENERGY REQUIREMENT FOR MUSCLE
postsynaptic cell CONTRACTION
Acetylcholinesterase AEROBIC – requires O2
● an enzyme that rapidly breaks down the RESPIRATION – breaks down glucose to produce
ATP, CO2, and H2O
synaptic cleft bet. the neuron and the
ANAEROBIC – doesn’t require O2
muscle fiber
RESPIRATION – breaks down glucose to yield
MUSCLE CONTRACTION ATP and lactic acid
CREATINE high-energy molecule that
Sliding filament model PHOSPHATE can be stored in muscle fibers
● sliding of actin myofilaments past myosin
myofilaments during contraction FATIGUE
Cross-bridges ● a state of reduced work capacity
→ Muscular fatigue
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● when muscle fibers use ATP faster than
they are produced
● when the effectiveness of Ca+ to stimulate
actin + myosin is reduced
→ Physiological contracture
● muscles may become incapable of either
contracting or relaxing
→ Psychological fatigue
● involves the CNS
● an individual perceives that continued
muscle contraction is impossible
MUSCLE TONE
● constant tension produced by body
muscles over long periods of time
● responsible for keeping the back and legs
straight, the head in an upright position,
and the abdomen from bulging
Isotonic contraction
● equal tension CLASSIFICATION OF MUSCLE FIBER
● the amount of tension produced by the 1. Slow Twitch
muscle is constant during contraction ● contains type I myosin
● length of the muscle decreases ● contracts slowly and resistant to fatigue
Cocentric contractions respiration
○ Isotonic 2. Fast Twitch
○ muscle tension increases as the ● Type IIa
muscle shortens — intermediate speed
Eccentric contractions — more fatigue resistant than type IIb
○ Isotonic ● Type IIb
○ tension is maintained in a muscle — contract 10x faster than type I
○ the opposing resistance causes
the muscle to lengthen Myglobin
● stores oxygen temporarily
Hypertrophy
● enlarging of muscle fibers
Satellite cells
● undifferentiated cells just below the
endomysium
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Origin
SMOOTH AND CARDIAC MUSCLE ● Head
Autorhythmicity ● most stationary end of the muscle
● resulting periodic spontaneous Insertion
contraction of smooth muscle ● end of the muscle attached to the bone
Intercalated disks undergoing the greatest movement
● specialized structures that facilitate action
potential conduction between cells
GENERAL PRINCIPLES
Tendon
● muscle connected to a bone
Belly
● part of the muscle bet. The origin & the
insertion
Agonist
● muscle that accomplishes a certain
movement
Antagonist
Aponeuroses ● muscle acting in opposition to an agonist
● Broad
● sheet like tendons
Retinaculum
● a band of CT that holds down the tendons
at each wrist and ankle
Synergists
● a group of muscles working together to
produce a movement
Prime Mover
● muscle that plays the major role in
acomplishing desired movement
K.A. YATCO
Fixators
● muscles that hold one bone in place
relative to the body
3. Accdg. to number of origin
● biceps (2)
● triceps
● Quadriceps
NOMENCLATURE
1. Accdg. to location
● Temporalis
● Frontalis
● Pectoralis
● Brachialis
4. Accdg. to function
● flexor (flexion)
2. Accdg. to origin and insertion
● sterno (sternum)
● cleido (clavicle)
● mastoid (mastoid process)
● brachio (arm)
● radialis (radius)
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7. Orientation of fasciculi
● rectus (straight)
6. Accdg. to shape
● deltoid (triangle
● orbicularis (circular)
Orbicularis oculi
● encircle the eyes, tightly close the eyelids,
and causes crow’s feet wrinkles
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Orbicularis oris Depressor anguli oris
● encircles the mouth ● frowning & pouting
● depresses the corner of the mouth
Buccinator
● issing muscles; pucker the mouth
MASTIFICATION (for chewing)
● Flattens the cheeks I whistling/blowing
Temporalis
● fan-shaped muscle
Masseter
● seen and felt on the side of the head
Pterygoid (paired)
● protraction, excursion, elevation of
mandible
Zygomaticus
● elevate the upper lip and corner of the
mouth Levator labile superioris – sneering
● elevates one side of the upper lip
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Hyoid muscles NECK MUSCLES
● hold the hyoid bone Sternocleidomastoid
● elevate the larynx ● prime mover of the lateral muscle group
● rotates the head
● flexes the neck or extends the head;
● prayer muscle
Pharyngeal elevators
● elevate the pharynx
Pharyngeal constrictors
Torticollis
● constrict the pharynx from superior to
● Wryneck – injury to the
inferior (forcing food into the esophagus
sternocleidomastoid
● also open the auditory tube
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TRUNK MUSCLES Scalenes
● Inspiration and rib elevation
MUSCLES MOVING THE VERTEBRAL COLUMN
Erector spinae
❖ responsible for keeping the back straight
and the body erect
Rectus abdominis
● located on each side of the linea alba
Diaphragm
● major movement produced in the thorax
during quiet breathing
Tendinous intersections
● causes the abdominal wall of a lean,
well-muscled person to appear segmented
External/Internal abdominal oblique &
Transversus abdominis
● flex and rotate the vertebral column or
compress the abdominal contents
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Perineum bulbospongiosus
● constricts the urethra
● erects the penis,
clitoris
Perineum ischiocavernosus
● compresses the
base of
penis/clitoris
Levator ani
● muscle that forms the pelvic floor
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UPPER LIMB MUSCLES Rotator cuff muscles
● attached the humerus to the scapula and
SCAPULAR MOVEMENTS forms a cuff/cap over the proximal
❖ attach the scapula to the thorax and move humerus
the scapula
❖ acts as fixators to hold the scapula firmly
in position when the muscle of the arm
contract
❖ move the scapula into different positions
➢ Trapezius
➢ Levator scapulae
➢ Rhomboids
➢ Serratus anterior
➢ Pectoralis minor
Deltoid
ARM MOVEMENTS
● attaches the humerus to the scapula and
Pectoralis major
clavicle
● adducts the arm and flexes the shoulder
● major abductor of the upper limb
● extend the shoulder from a flexed position
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SUPINATION AND PRONATION Intrinsic hand muscles
Supinator ● 19 muscles located within the hand
● supination of the forearm or turning the
flexed forearm so that the palm is up
Pronator
● pronation, turning other forearm so that
the palm is down
Interossei
● responsible
for
abduction
and
adduction
of the
WRIST AND FINGER MOVEMENTS fingers
Retinaculum
● fibrous connective tissue that covers the
flexor & extensor tendons and holds them Tennis elbow
in place around the wrist ● inflammation and pain due to forceful,
repeated contraction of the wrist extensor
muscles
Flexor carpi
● flex the wrist
Extensor carpi
● extend the wrist Palmus longus
● tightens palm skin
Flexor digitorum
● flexor of the digits/fingers
Extensor digitorum
● extension of the fingers
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UPPER LIMB MUSCLES LEG MOVEMENTS
Quadriceps femoris
THIGH MOVEMENTS ● primary extensors of the knee
Iliopsoas
● flexes the hip
Gluteus maximus
● extends the hip; adducts and laterally
rottes the thigh
● contributes most of the mass
Gluteus medius
● extends the hop when the thigh is flexed
at a 45O angle
● common site for injections in the buttocks
(sciatic nerve lies deep to the g. maximus)
Hamstring muscles
● flexing the knee
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Adductor muscles
● adducting the thigh
Fibularis muscles
● primary everters of the foot
● aid inplantar flexion
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Tibialis anterior
● inverts foot
Fibularis tertius
● everts foot
Fibularis brevis
● everts foot
Fibularis longus
Flexor digitorum longus ● everts foot
● flexes 4 lateral toes, inverts foot
Tibialis posterior
● inverts foot
K.A. YATCO
K.A. YATCO