SCHOOL OF NURSING AND ALLIED HEALTH STUDIES

BACHELOR OF SCIENCE IN NURSING

COURSE SYLLABUS
MCC110 BIOCHEMISTRY

AY 2023 – 2024
SDCA Vision: A community of dynamic and proactive scholars and learners within the Asia-Pacific Region, upholding the highest standards of
excellence in education, research, and community service towards the attainment of a better quality of life.

SDCA Mission: To purposively link quality education, training and research with community service in pursuing the holistic development of
individuals through innovative programs and productive activities attuned to the needs of the global community.

Goals: St. Dominic College of Asia aims to:

1. Prepare the students to become competent, productive, and socially responsible professional.
2. Actively promote research and the utilization of new technology for the enhancement of individual competencies.
3. Assume leadership role in addressing the concerns of the academic community towards improving their quality of life.

SDCA Core Values: S - Service D - Dynamism C - Competence A – Accountability

SDCA QUALITY OF LIFE FORMULA:

1. Research & Product Development: Demonstrate ability to develop researches and to produce scientific and entrepreneurial outputs.
2. Moral and Spiritual Accountability: Embrace moral/spiritual values in living one’s life. Apply moral/spiritual practices in all aspects of
life.
3. Multicultural Advocacy: Demonstrate knowledge of values and beliefs of various cultures; effectively engage in a multicultural society;
interact with others; develop a global perspective.

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 4. Understanding the Discipline: Demonstrate a systematic and coherent understanding of an academic field of study.
5. Self- Directed Learning: Work independently; identify appropriate resources; take initiative; take a lead in managing a project or an
activity through completion.

6. Information and Technology Literacy: Access, evaluate, use variety of relevant sources and produce materials of the same.
7. Critical Thinking: Identify relevant assumptions or implication; evaluate arguments; apply analytic thought to analyze coherent
arguments.
8. Communication Skills: Express ideas clearly in unity; speak articulately; use media as appropriate in order to communicate effectively.
9. Creativity and Innovation: Demonstrate ability to work creatively and innovatively in any setting that result in a productive output.
10. Collaboration and Community Engagement: Demonstrate responsible participation; engage in meaningful activities in the academe, in the
community, and beyond.

PROGRAM EDUCATIONAL OBJECTIVES (PEO): Bachelor of Science in Nursing

At the end of the program, the graduates of the Bachelor of Science in Nursing are expected to:

1. Demonstrate beginning nurse competencies in client care in accordance with the professional standards in nursing practice applied in
various reputable health care settings.
2. Apply the role of the nurse in leadership and management utilizing interpersonal communication, collaboration, decision making and
organizational skills applied in various settings.
3. Demonstrate involvement in health-related research activities that will contribute in the development of clients, families, communities
and the nursing profession.
4. Exhibit professional values through service, dynamism, commitment to excellence, and accountability.

PROGRAM OUTCOMES (PO):

A. Apply knowledge of physical, social, natural and health sciences and humanities in the practice of nursing.
1. Integrate relevant principles of social, physical, natural and health sciences and humanities in the given health nursing situation.
2. Apply appropriate nursing concepts and actions holistically and comprehensively.

B. Performance of safe, appropriate and holistic care to individuals, families, population groups and community utilizing nursing
process.
1. Assess with the client (individual, family, population group, and/or community) one’s health status/competence.

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 2. Formulate with the client a plan of care to address the health conditions, needs, problem and issues.
3. Implement safe and quality intervention with the clients to address the health needs, problems and issues.
4. Provide health education using selected planning models to targeted clientele (individual, family, population group, and/or
community).
5. Evaluate with the client the health status/competence and/or process expected outcomes of nurse-client working relationship.
6. Institute appropriate corrective actions to prevent or minimize harm arising from adverse effects.

C. Apply guidelines and principles of evidence-based practice in the delivery care.

1. Provide appropriate evidence-based nursing care using a participatory approach based on a variety of theories and standards relevant
to health and healing,
2. Research
3. Clinical practice
4. Client reference
5. Client and staff safety
6. Customers care standards

D. Practice nursing in accordance with the existing laws, legal ethical and moral principles.
1. Adhere to ethico–legal considerations when providing safe, quality and professional nursing care.
2. Apply ethical reasoning and decision making process to address situations of ethical distress and moral dilemma.
3. Adhere to established norms of conduct based on the Philippine Nursing Law and other legal, regulatory and institutional
requirements relevant to safe nursing practice.
4. Protect clients right based on the “Patient’s Bill of Rights and Obligations.”
5. Implement strategies/policies related informed consent as it applies in multiple context

E. Communicate effectively in speaking, writing and presenting using culturally appropriate language.
1. Ensure a working relationship with the client and/or support system based on trust, respect and shared decision–making using
appropriate communication/interpersonal techniques / strategies.

F. Report/document client care accurately and comprehensively.

1. Document client’s response/nursing care services rendered and process outcomes of the nurse/clients working relationship.
2. Ensure completeness, integrity, safety, accessibility and security of information.
3. Adhere to protocol and principles of confidentiality in safekeeping and releasing of records and other information.

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G. Collaborate effectively with inter–intra and multi-disciplinary and multi-cultural teams.
1. Ensure intra-agency, inter-agency, multidisciplinary and sectoral collaboration in the delivery of health care.
2. Implement strategies/approaches to enhance/support the capability of the client and care providers to participate in decision making by
the inter-professional team.
3. Maintain a harmonious and collegial relationship among members of the health team for effective, efficient and safe client care.
4. Coordinate the tasks/functions of other nursing personnel (midwife and utility worker)
5. Collaborate with other members of the health team in the implementation of programs and services.
6. Apply principles of partnership and collaboration to improve delivery of health services.
7. Collaborate with NGOs and other socio-civic agencies to improve health care services, support environment protection policies and
strategies, and safety and security mechanisms in the community.
8. Participate as a member of a quality team in implementing the appropriate quality improvement process on identified improvement
opportunities.

H. Practice beginning management and leadership skills using systems approach in the delivery of client care.
1. Participate in the development and improvement of policies and standards regarding safe nursing practice and relevant to human
resources management.
2. Manage resources (human, physical, financial, time) efficiently and effectively.
3. Apply management and leadership principles in providing direction to manage a community/village.
4. Use appropriate strategies/approaches to plan community health programs and nursing services.
5. Supervise the implementation of the nursing component of the health services/programs.
6. Ensure that all nursing personnel adhere to standards of safety, bioethical principles and evidence-based nursing practice.
7. Evaluate specific components of health programs and nursing services based on parameters/criteria.
8. Maintain a positive practice environment.
9. Participate in planning and implementation of staff development activities to enhance performance of nursing support staff.
10. Evaluate performance of nursing support staff using a standard evaluation tool.

I. Conduct research with an experienced researcher.

1. Participate in preparing a research proposal complying with the ethical principles in the nursing research.
2. Conduct a research study as a member of a research team.
3. Determine if the research problems/questions, learning outcomes and/or hypotheses are clearly and logically linked to the research
purpose, concept and relationship, and propositions generated from the study framework.
4. Analyze if the conceptual framework the summary of review of related literature, research design, and data analysis procedure are
logically linked with the research purpose, problems/questions, and hypotheses.

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 5. Establish if the interpretation, implications and recommendations are consistent with the results considering the limitations of the
study.
6. Analyze the research study/report for adherence to standards of writing mechanics, ethical principle and guidelines in all phases of the
research study.
7. Present the research study conducted in partnership with the research team.

J. Engage in lifelong learning with a passion to keep current with national and global developments in general nursing and health
developments in particular.
1. Assume responsibility for the lifelong learning, own personal development and maintenance of competence.
2. Demonstrate continued competence and professional growth.
3. Engage in advocacy activities to influence health and social care service policies and access to services.
4. Model professional behavior.
5. Engage in advocacy activities to deal with the health related concerns and adopts policy that offers the growth and development of the
nursing profession.

K. Demonstrate responsible citizenship and pride in being a Filipino.

1. Exemplify love for country in the service of the Filipinos.
2. Customize nursing intervention based on the Philippines’ culture and values.

L. Apply techno-intelligent care systems and processes in health care delivery.

1. Use appropriate technology to perform safe and efficient nursing activities.
2. Implement system of informatics to support the delivery of health care.

M. Uphold the nursing core values in the practice of the profession.

1. Demonstrate caring as the core of nursing, love of God, love of country and love of people.
2. Manifest professionalism, integrity and excellence.
3. Project the positive professional image of Filipino nurses.

N. Develop entrepreneurial skills in the delivery of nursing care.

1. Specify appropriate financial strategies to address health related concerns.
2. Apply appropriate financial strategies to address health related concerns and employ financial policies foster growth and development
of the nursing profession.

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COMMON TO A HORIZONTAL TYPE AS DEFINED IN CMO 46 S. 2012

GRADUATES OF PROFESSIONAL INSTITUTIONS DEMONSTRATE A SERVICE ORIENTATION IN ONE’S PROFESSION.

Common to a SDCA Graduate (Based on SDCA Quality of Life Formula)

The SDCA graduates have the ability to:

1. Apply critical and research skills using technologically relevant resources /materials.
2. Engage effectively in meaningful activities in a multi-cultural society.
3. Accomplish tasks independently and creatively, and express ideas articulately.

COURSE SYLLABUS
MCC110 BIOCHEMISTRY
AY 2023-2024

Subject Code : MCC110

Subject Title : BIOCHEMISTRY

No. of Units : Five (5) Units

Lecture Hours/Week : Three (3) Hours

Laboratory hours/week : Six (6) Hours

Placement : First Year BS Nursing Students, 1st Semester AY 2023-2024

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COURSE DESCRIPTION

This course covers the fundamental biochemistry concepts and theories for nursing majors. As a branch of life science, it deals with the study of
chemical reactions that occur in living cells and organisms. Life is a chemical process involving thousands of different reactions occurring in an
organized manner. It takes into account the studies related to the nature of the chemical constituents of living matter, their transformations in
biological systems and the energy changes associated with these transformations.

COURSE OBJECTIVES

At the end of the course, the students should be able to:

1. Appreciate the importance of biochemistry in improving the quality of life
2. Identify and analyze the structures of the different classes of biomolecules
3. Correlate properties of biomolecules with their structures
4. Describe the different aspects of metabolism and the principles involved in the metabolic abnormalities and diseases
5. Use thermodynamic principles in explaining energetics
6. Demonstrate fundamental experimental techniques in biochemistry

RELATIONSHIPS OF COURSE OBJECTIVES (CO), SDCA GOALS, NURSING PROGRAM OUTCOMES (PO),

AND PROGRAM EDUCATIONAL OBJECTIVES (PEO)

PROGRAM
COURSE OBJECTIVES (CO) SDCA GOALS NURSING PROGRAM OUTCOMES (PO) EDUCATIONAL
OBJECTIVES (PEO)

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 1 2 3 A B C D E F G H I J K L M N 1 2 3 4

CO1: Appreciate the X X X X

importance of
X X X X X X X X X X X X X X X X
biochemistry in X
improving the quality
of life

CO2: Identify and X X X

X X X X X X X X X X X X
analyze the structures X
of the different classes
of biomolecules

CO3: Correlate
X X X X
properties of
biomolecules with their X
X X X X X X X X X X X X X X X
structures

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 CO4: Describe the
different aspects of
metabolism and the
X X X X
principles involved in
the metabolic
abnormalities and
diseases

CO5: Use
thermodynamic
X X X X X X X X X X X X X
principles in explaining
energetics

CO6: Demonstrate
fundamental
experimental
techniques in
biochemistry

COURSE OUTLINE AND TIMEFRAME

Week Course Content/Subject Matter

1 Review of chemical bonding

A. Chemical bonding: the ionic bond model

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 Valence electrons

The octet rule

The ionic bond model

Chemical formulas for ionic compounds

Recognizing and naming binary ionic compounds

Polyatomic ions

Chemical formulas and names for ionic compounds containing polyatomic ions

B. Chemical bonding: the covalent bond model

Lewis structures for molecular compounds

Single, double, and triple covalent bonds

Valence electrons and number of covalent bonds formed

Coordinate covalent bonds

Molecular geometry

Electronegativity and polarity

Recognizing and naming binary molecular compounds

Review of chemical reactions

Collision theory, activation energy, and types of chemical reactions

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 Exothermic and endothermic chemical reactions

Factors that influence chemical reaction rates

Chemical equilibrium and the Le Chatelier’s principle

Redox reaction, chemical cell and the Nernst equation

Review of acids, bases, and salts

The three basic concepts of acids and bases

Ionization constants and the strengths of acids and bases

Salts

Acid-Base neutralization chemical reactions

Self-ionization of water

The pH concept

Buffers

The Henderson-Hasselbach equation

2 Review of the structures of organic compounds and their functional groups and properties

Hydrocarbons

Compounds containing oxygen, nitrogen, sulfur and phosphorous

Chemical reactions in organic reactions

3 Introduction to Biochemistry

Levels of structural organization

Prokaryotic and eukaryotic cells

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 Animal and plant cells

Cell organelles and their functions

Proteins Part 1

Characteristics of proteins

Amino acids

Essential amino acids

Chirality and amino acids

Acid-Base properties of amino acids

Peptides
Proteins Part 2

General structural characteristics of proteins

4
Primary structure of proteins

Secondary structure of proteins

Tertiary structure of proteins

Quaternary structure of proteins

Protein hydrolysis

Protein denaturation

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 Protein classification based on shape and function

Conjugated proteins
“Substitutes” for human insulin

Denaturation and human hair

5
Protein structure and the color of meat

Cyclosporine: An injection drug

Colostrum: Immunoglobulins and much more

Lipoproteins and heart disease risk

6 Prelim Examination

Enzymes and Vitamins Part 1

7
General characteristics of enzymes

Enzyme structure

Nomenclature and classification of enzymes

Models of enzyme action

Enzyme specificity

Enzyme inhibition

Enzyme regulation

Medical uses of enzymes

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 Enzymes and Vitamins Part 2
8
General characteristics of vitamins

Water-soluble vitamins

Fat-soluble vitamins

H. pylori and stomach ulcers

Carbohydrates Part 1
9
Classification of carbohydrates

Structure and isomerism in carbohydrates

Classification of monosaccharides

Biochemically important monosaccharides

Reactions of monosaccharides

Disaccharides

Oligosaccharides
Carbohydrates Part 2
10
General characteristics of polysaccharides

Storage polysaccharides

Structural polysaccharides

Dietary considerations and carbohydrates

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 Glycolipids and glycoproteins cell recognition

Lactose intolerance

Blood types and oligosaccharides

Edible fibers and health

Lipids
11
Structure and classification of lipids

Types of fatty acids

Physical properties of fatty acids

Energy -storage lipids: TAG

Dietary considerations and TAG

Membrane lipids: phospholipids

Membrane lipids: sphingolipids

Membrane lipids: cholesterol

Cell membrane

Emulsification of lipids

Messenger lipids: Steroid hormones

Messenger lipids: Eicosanoids

Trans-fat content of some foods

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 Anabolic steroid use in competitive sports

Mode of action for anti-inflammatory drugs

12 Midterm Examination

Nucleic acids Part 1

13 Types of nucleic acids
Nucleotide
The DNA and RNA
The central dogma

Nucleic acids Part 2

14 Genetic mutations

Nucleic acids and viruses

Antimetabolites: Anticancer drugs

Antibiotic protein synthesis inhibitors

Erythropoietin (EPO): Red blood cells, mutations, and athletic performance

Biochemical Energy Production
15
Metabolism overview

Metabolism and cell structure

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 Important nucleotide-containing compounds in metabolic pathways

Important carboxylate ions in metabolic pathways

High-energy phosphate compounds

Carbohydrate metabolism

Digestions and absorption of carbohydrates

Glycolysis

Fates of pyruvate

ATP production

Glycogen synthesis and degradation

Gluconeogenesis

Pentose Phosphate Pathway

Hormonal control of carbohydrate metabolism

Lactate accumulation

Diabetes mellitus
Lipid metabolism
16 Digestion and absorption of lipids

TAG storage and mobilization

Glycerol metabolism

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 Beta-oxidation pathway

Ketone bodies and ketogenesis

B vitamins and lipid metabolism

High-intensity versus low-intensity workouts

Statin
Protein metabolism
17 Protein digestion and absorption

Amino acid utilization

The urea cycle

Amino acid carbon skeletons

Hemoglobin catabolism

Proteins and the element Sulfur

Integrated metabolic pathways

Chemical composition of urine

Arginine, citrulline, and nitric oxide

18 Final Examination

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LEARNING PLAN

Week Course Intended Course Intended Values Teaching- Assessment Resources,

Number Learning Outcomes Deployed Learning Tasks Textbooks &
Activities References

Review of chemical
1 Understand the difference bonding Service Lecture Discussion Quiz
between ionic bonding Chang, R. (2009).
and covalent bonding. A. Chemical bonding: Competence Lecture Chang, Chemistry ©
the ionic bond Demonstration 2010, 10e, Student
Recognize the difference model Responsibility on Lab Safety Edition. NewYork:
between ionic Guidelines McGraw-Hill
compounds and Valence electrons Education
molecules from the
nature of the bond. The octet rule
Campbell, M.K. &
Write the appropriate The ionic bond
chemical formula of ionic model Farrell, S.O. (2015).
compounds and Biochemistry (8th
molecules Chemical formulas ed.). Stamford CT:
for ionic Brooks Cole/Cengage
Understand how single compounds Learning Asia Pte
bond and multiple bonds Ltd.
form. Recognizing and
naming binary ionic Villarante, Nelson R.
Recognize the difference compounds (2015). Laboratory
in between single bond, Manual in
double bond, and triple Polyatomic ions Biochemistry.
bond based on their Bacoor City: SDCA.
reactivity. Chemical formulas
and names for ionic
Understand how polar compounds
molecules arise based on containing

Page 19 of 41
the electronegativities of polyatomic ions
the atoms/elements
involved in bonding.
B. Chemical bonding:
Understand how the covalent bond
chemical reactions take model
place based on collision
theory. Lewis structures for
molecular
Recognize the difference compounds
between endothermic and
exothermic reactions and Single, double, and
predict the triple covalent
thermodynamic stability bonds
of the system.
Valence electrons
Understand the how some and number of
chemical reactions covalent bonds
approach equilibrium and formed
use the Le Chatelier’s
principle to predict which Coordinate
direction it will favor covalent bonds
upon application of stress
to the system. Molecular
geometry
Recognize the difference
between each type of Electronegativity
chemical reaction. and polarity

Understand how to Recognizing and

balance redox reactions naming binary
and how to construct molecular
electrochemical cells. compounds

Understand how
spontaneous reactions
from electrochemical

Page 20 of 41
cells can be used to Review of chemical
extract some useful work. reactions

Recognize the difference Collision theory,

between the basic activation energy,
concepts of acids and and types of
bases. chemical reactions

Understand how acidity Exothermic and

and basicity can be endothermic
described using pH. chemical reactions

Determine the pH of a Factors that

solution of strong acid influence chemical
and weak acid. reaction rates

Understand how a Chemical

solution of buffer resists equilibrium and the
drastic changes in pH. Le Chatelier’s
principle
Understand how to use
the Henderson- Redox reaction,
Hasselbach equation to chemical cell and
determine the pH of a the Nernst equation
buffer.

Review of acids, bases,

and salts

The three basic

concepts of acids
and bases

Ionization constants
and the strengths of
acids and bases

Salts

Page 21 of 41
 Acid-Base
neutralization
chemical reactions

Self-ionization of
water

The pH concept

Buffers

The Henderson-
Hasselbach equation

2 Describe how carbon Review of the structures Competence Lecture Discussion Quiz
bonds with other of organic compounds Campbell, M.K. &
elements and their functional Lecture Practical Farrell, S.O. (2015).
groups and properties Demonstration on exam Biochemistry (8th
Classify organic Lab Apparatus, ed.). Stamford CT:
compounds based on Brooks Cole/Cengage
their functional groups Hydrocarbons Equipments and Learning Asia Pte
Set Ups Ltd.
Give examples of these Compounds containing
classes of compounds by oxygen, Research on Villarante, Nelson R.
giving their structural nitrogen, Amphetamines (2015). Laboratory
formula and their uses sulfur and Manual in
phosphorous Biochemistry.
Identify the different Bacoor City: SDCA.
reactions in organic
compounds

3 Discuss the different Introduction to Service Lecture Discussion Quiz

intermolecular forces of Biochemistry Stoker, H. S. (2011).
attraction Responsibility Group Activity Group Biochemistry.
Levels of Report Quezon City: C & E
Explain the polarity of structural Cooperation Perform Publishing,
water and its nature as the organization Experiment on pH Lab Report Inc./Cengage

Page 22 of 41
universal solvent Teamwork and Buffers Learning.
Prokaryotic and
Appreciate the unusual eukaryotic cells Post Lab Campbell, M.K. &
properties of water Judgement Discussion Farrell, S.O. (2015).
Animal and plant Biochemistry (8th
Define acids, bases and cells ed.). Stamford CT:
pH Brooks Cole/Cengage
Cell organelles Learning Asia Pte
Discuss how buffers and their functions Ltd.
work
Proteins Part 1 Villarante, Nelson R.
Describe the structure (2015). Laboratory
and properties of amino Manual in
Characteristics of
acids Biochemistry.
proteins Bacoor City: SDCA.
Classify amino acids into
their various type Amino acids Landesberg, J.
(2012). Basic
Know the one-letter and Essential amino Laboratory
three-letter designations acids Experiments for
of amino acids General, Organic
Chirality and and Biochemistry.
Determine the chirality amino acids Australia: Brooks
and stereochemistry of Cole/ Cengage
amino acid Acid-Base Learning.
properties of
Determine the isoelectric amino acids
point of an amino acid

Know the various forms Peptides

of amino acids based on
the pH

Draw dipeptides based on

the amino acid
composition

Page 23 of 41
 Proteins Part 2
4 Characterize protein Dynamism Lecture Discussion Quiz
structure based on their Stoker, H. S. (2011).
General structural
architectural Competence Oral Presentation Biochemistry.
characteristics of
arrangement Quezon City: C & E
proteins
Cooperation Group Activity Group Publishing,
Describe protein Report Inc./Cengage
Primary structure
isolation and purification Teamwork Perform Learning
of proteins
techniques Experiment on
Amino Acid Bettelheim, F. A.,
Be able to sequence Secondary Analysis and Paper Lab Reports Brown W.H. &
short peptide chains structure of Chromatography Campbell M.K.
proteins (2018).
Describe peptide Post Lab Biochemistry.
synthesis methods Tertiary structure Discussion Quezon City: C & E
of proteins Pub., Inc./Cengage
Describe post- Learning.
translational Quaternary
modifications of proteins structure of Villarante, Nelson R.
proteins (2015). Laboratory
Describe the different Manual in
levels of protein Biochemistry.
structure Protein hydrolysis
Bacoor City: SDCA.

Distinguish the different Protein Landesberg, J.

types of common denaturation (2012). Basic
secondary structures Laboratory
Protein Experiments for
Identify the interactions classification General, Organic
that stabilize the based on shape and Biochemistry.
different protein and function Australia: Brooks
structural levels Cole/ Cengage
Conjugated Learning.
Identify the forces that
proteins
stabilize a protein
structure

Page 24 of 41
 Describe the process of
protein folding

Describe the role of

chaperones in protein
folding

Discuss diseases that are

caused by misfolded
proteins

5 Explain and apply the “Substitutes” for human Dynamism Lecture Discussion Quiz Stoker, H. S. (2011).
concepts of protein insulin Biochemistry.
structure and function to Competence Oral Presentation Quezon City: C & E
different real-life Denaturation and human Publishing,
scenarios hair Cooperation Group Activity Group Inc./Cengage
Report Learning
Teamwork Perform
Protein structure and the
Experiment on Bettelheim, F. A.,
color of meat Isolation and Brown W.H. &
Tests on Proteins Lab Reports Campbell M.K.
Cyclosporine: An
(2018).
injection drug Post Lab Biochemistry.
Discussion
Quezon City: C & E
Colostrum:
Pub., Inc./Cengage
Immunoglobulins and
Learning.
much more
Villarante, Nelson R.
Lipoproteins and heart (2015). Laboratory
disease risk Manual in
Biochemistry.
Bacoor City: SDCA.

Landesberg, J.

Page 25 of 41
 (2012). Basic
Laboratory
Experiments for
General, Organic
and Biochemistry.
Australia: Brooks
Cole/ Cengage
Learning.

6 Prelim
Examination

7 Define the general Enzymes and Vitamins Accountability Lecture Discussion Quiz Stoker, H. S. (2011).
properties of an enzyme Part 1 Biochemistry.
Responsibility Group Activity Group Quezon City: C & E
Draw an energy diagram General Report Publishing,
of characteristics of Cooperation Perform Inc./Cengage
catalyzed and experiments on Lab Report Learning
enzymes
uncatalyzed reactions Teamwork Enzyme Hydrolysis
and identify its parts of Starch Bettelheim, F. A.,
Enzyme structure
Brown W.H. &
Discuss how the activity Campbell M.K.
of an enzyme is Nomenclature and Post Lab (2018).
regulated classification of Discussion Biochemistry.
enzymes
Quezon City: C & E
Provide examples on
how enzyme inhibition is Pub., Inc./Cengage
Models of enzyme
useful in drug design Learning.
action
Villarante, Nelson R.
Differentiate the overall Enzyme (2015). Laboratory
structure and function of specificity Manual in
myoglobin and Biochemistry.
hemoglobin Bacoor City: SDCA.
Enzyme inhibition
Describe the oxygen- Landesberg, J.

Page 26 of 41
 binding properties of Enzyme (2012). Basic
myoglobin and regulation Laboratory
hemoglobin Experiments for
Medical uses of General, Organic
Describe how oxygen enzymes and Biochemistry.
binds to hemoglobin Australia: Brooks
Identify the factors that Cole/ Cengage
affect the affinity of Learning.
hemoglobin for oxygen

Describe the different

states of hemoglobin in
oxygen binding
Stoker, H. S. (2011).
8 Describe the functions of Enzymes and Vitamins Lecture Discussion Quiz Biochemistry.
enzymes in the proper Part 2 Quezon City: C & E
functioning of enzymes Group Activity Group Publishing,
General Report Inc./Cengage
Identify the different characteristics of Perform Learning
vitamins that are water- vitamins experiment on Lab Report
soluble Analysis of Bettelheim, F. A.,
Vitamin C in Food Brown W.H. &
Water-soluble
Identify the different Products Campbell M.K.
vitamins that are fat- vitamins
(2018).
soluble Post Lab Biochemistry.
Fat-soluble Discussion Quezon City: C & E
Apply the knowledge vitamins
Pub., Inc./Cengage
about enzymes and
Learning.
vitamins in explaining H. pylori and stomach
real-life scenarios. ulcers Villarante, Nelson R.
(2015). Laboratory
Manual in
Biochemistry.
Bacoor City: SDCA.

Landesberg, J.
(2012). Basic

Page 27 of 41
 Laboratory
Experiments for
General, Organic
and Biochemistry.
Australia: Brooks
Cole/ Cengage
Learning.

Stoker, H. S. (2011).
9 Biochemistry.
Define monosaccharides; Carbohydrates Part 1 Competence Lecture Discussion Quiz Quezon City: C & E
draw structures of Publishing,
monosaccharides Classification of Caring Research on Group Inc./Cengage
using Fischer carbohydrates Diabetes Report Learning
projections and Haworth Cooperation
projections; Group Activity Bettelheim, F. A.,
Structure and
Teamwork Lab Reports Brown W.H. &
Explain the reactions of isomerism in Perform Campbell M.K.
monosaccharides; carbohydrates experiments on (2018).
draw disaccharides and Isolation and Tests Biochemistry.
glycosidic bonds; Classification of for Carbohydrates Quezon City: C & E
monosaccharides
Pub., Inc./Cengage
Distinguish a Post Lab
Learning.
monosaccharide from a Biochemically Discussion
disaccharide, and from important Villarante, Nelson R.
an oligosaccharide monosaccharides (2015). Laboratory
Manual in
Distinguish the classes Reactions of Biochemistry.
of monosaccharides Bacoor City: SDCA.
monosaccharides
based on chemical
reactions.
Disaccharides

Oligosaccharides

10 Describe the structure Carbohydrates Part 2 Lecture Discussion Quiz Stoker, H. S. (2011).
and composition of Biochemistry.

Page 28 of 41
 certain polysaccharides General Group Activity Group Quezon City: C & E
characteristics of Report Publishing,
Relate the structure of polysaccharides Perform Inc./Cengage
certain polysaccharides experiment on Lab Reports Learning
to their functions Storage Alcohol
Fermentation Bettelheim, F. A.,
polysaccharides
Describe the Brown W.H. &
composition Post Lab Campbell M.K.
Structural
glycoprotein and its Discussion (2018).
function polysaccharides
Biochemistry.
Quezon City: C & E
Apply the knowledge Dietary
Pub., Inc./Cengage
about carbohydrates in considerations and
Learning.
explaining real-life carbohydrates
scenarios Villarante, Nelson R.
(2015). Laboratory
Manual in
Biochemistry.
Bacoor City: SDCA.

11 Classify lipids based on Lipids Accountability Lecture Discussion Quiz

their structure Stoker, H. S. (2011).
composition Structure and Competence Group Activity Group Biochemistry.
classification of Report Quezon City: C & E
Describe the physical lipids Cooperation Perform Publishing,
properties of fatty acids Experiment on Lab Report Inc./Cengage
Teamwork Analysis of Lipids Learning
Types of fatty
Describe the function of in Egg and Milk
acids Bettelheim, F. A.,
various lipids
Post Lab Brown W.H. &
Draw the structure of Physical Discussion Campbell M.K.
triglycerides properties of fatty (2018).
acids Biochemistry.
Understand the function Quezon City: C & E
of different lipids Energy -storage Pub., Inc./Cengage
lipids: TAG

Page 29 of 41
 Apply the knowledge in Learning.
lipids to explain real-life Dietary
scenarios Villarante, Nelson R.
considerations and
(2015). Laboratory
TAG
Manual in
Biochemistry.
Membrane lipids: Bacoor City: SDCA.
phospholipids

Membrane lipids:
sphingolipids

Membrane lipids:
cholesterol

Cell membrane

Emulsification of
lipids

Messenger lipids:
Steroid hormones

Messenger lipids:
Eicosanoids

Trans-fat content
of some foods
Anabolic steroid
use in competitive
sports

Mode of action for anti-

inflammatory drugs

12 Midterm

Page 30 of 41
 Examination

Nucleic acids Part 1

13 Identify the components Lecture Discussion Quiz Stoker, H. S. (2011).
that comprise a nucleic Types of nucleic Biochemistry.
acid acids Research on Group Quezon City: C & E
Cloning Report Publishing,
Nucleotide
Differentiate purine and Inc./Cengage
pyrimidine bases The DNA and Group Activity Lab Report Learning
RNA
Determine the sugars Perform Bettelheim, F. A.,
and bases that compose The central dogma Experiment on Brown W.H. &
an RNA or DNA Isolation and Campbell M.K.
molecule Characterization (2018).
of DNA Biochemistry.
Quezon City: C & E
Describe the Post Lab
complementary base Discussion Pub., Inc./Cengage
pairs Learning.
Villarante, Nelson R.
Identify the linkage (2015). Laboratory
formed in DNA and RNA Manual in
molecules Biochemistry.
Bacoor City: SDCA.
Differentiate the overall
structure of an RNA and
DNA molecule

Describe the Watson and

Crick model of the DNA
Describe the function of
DNA and RNA
molecules
Nucleic acids Part 2
14 Utilize the knowledge in Lecture Discussion Quiz
the structure and function Genetic mutations Stoker, H. S. (2011).
of nucleic acids in Group Activity Group Biochemistry.

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 understanding real-life Nucleic acids and Report Quezon City: C & E
scenarios viruses Publishing,
Inc./Cengage
Antimetabolites: Project on Learning
Anticancer drugs Genetic Code
Bettelheim, F. A.,
Brown W.H. &
Antibiotic protein
Campbell M.K.
synthesis
(2018).
inhibitors
Biochemistry.
Quezon City: C & E
Erythropoietin (EPO):
Red blood cells, Pub., Inc./Cengage
mutations, and athletic Learning.
performance Villarante, Nelson R.
(2015). Laboratory
Manual in
Biochemistry.
Bacoor City: SDCA.

15 Describe the general idea Biochemical Energy

of biochemical energy Production Lecture Discussion Quiz Stoker, H. S. (2011).
production Biochemistry.
Metabolism Group Activity Group Quezon City: C & E
Identify the difference overview Report Publishing,
between catabolism and Perform Inc./Cengage
anabolism Experiment on Lab Report Learning
Metabolism and
Mitochondrial
cell structure
Identify the important Respiration Bettelheim, F. A.,
molecules participating in Brown W.H. &
metabolic pathways Important Post Lab Campbell M.K.
nucleotide- Discussion (2018).
Describe the structure of containing
Biochemistry.
ATP compounds in
Quezon City: C & E
metabolic
Understand how Pub., Inc./Cengage
pathways
carbohydrate is used to

Page 32 of 41
get ATP by the cell Important Learning.
carboxylate ions
Identify the different Villarante, Nelson R.
in metabolic
enzymes involved in (2015). Laboratory
pathways
different carbohydrate Manual in
metabolic pathways and Biochemistry.
High-energy Bacoor City: SDCA.
they are regulated
phosphate
compounds
Utilize the knowledge in
carbohydrate metabolism
in understanding real-life Carbohydrate
scenarios metabolism

Digestions and
absorption of
carbohydrates

Glycolysis

Fates of pyruvate

ATP production

Glycogen
synthesis and
degradation

Gluconeogenesis

Pentose Phosphate
Pathway

Hormonal control
of carbohydrate
metabolism

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 Lactate
accumulation

Diabetes mellitus
Lipid metabolism
16 Trace the digestion, Lecture Discussion Quiz Stoker, H. S. (2011).
transport, and storage of Digestion and Biochemistry.
triacylglycerols and fatty absorption of Group Activity Group Quezon City: C & E
acids, including the role lipids Report Publishing,
of the different Perform Inc./Cengage
lipoproteins (HDL, LDL, TAG storage and Experiment on Lab Report Learning
VLDL) Analysis of Urine
mobilization
Bettelheim, F. A.,
Identify the hormones Brown W.H. &
involved in the Glycerol Post Lab Campbell M.K.
metabolism of dietary metabolism Discussion (2018).
triacylglycerols Beta-oxidation
Biochemistry.
pathway
Quezon City: C & E
Compare the ATP yield
in B-oxidation and Pub., Inc./Cengage
Ketone bodies and
glycolysis Learning.
ketogenesis
Villarante, Nelson R.
Identify the end product B vitamins and (2015). Laboratory
of B-oxidation lipid metabolism Manual in
Biochemistry.
Relate B-oxidation to Bacoor City: SDCA.
High-intensity
citric acid cycle and
electron transport chain versus low-
intensity workouts
Relate the production
and significance of Statin
ketone bodies to B-
oxidation

Trace the biosynthesis of

fatty acids,

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 triacylglycerols and
cholesterol and identify
its control points

Utilize the knowledge in

lipid metabolism in
understanding real-life
scenarios.
Protein metabolism
17 Define transamination Lecture Discussion Quiz Stoker, H. S. (2011).
reaction Protein digestion and Biochemistry.
absorption Group Activity Group Quezon City: C & E
Trace the biosynthesis of Report Publishing,
the following families of Amino acid utilization Perform Inc./Cengage
amino acids: Experiment on Lab Report Learning
Glutamate family The urea cycle Enzyme Kinetics
Aspartate family Bettelheim, F. A.,
Serine family Amino acid carbon Post Lab Brown W.H. &
Pyruvate family skeletons Discussion Campbell M.K.
Aromatic family (2018).
Histidine family Hemoglobin catabolism Biochemistry.
Describe the urea cycle
Quezon City: C & E
and state its importance Proteins and the element
Write an equation for the Sulfur Pub., Inc./Cengage
net reaction of the urea Learning.
cycle Integrated metabolic Villarante, Nelson R.
pathways (2015). Laboratory
Show how urea cycle is Manual in
linked to the citric acid Chemical composition Biochemistry.
cycle of urine Bacoor City: SDCA.
Show how different Arginine, citrulline, and
metabolic pathways are nitric oxide
interconnected to one
another

Understand the

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 breakdown of
hemoglobin

Identify the chemical

components of urine

Utilize knowledge in
protein metabolism in
understanding real-life
scenarios

Final
18 Examination

REQUIRED TEXTBOOKS AND LABORATORY MANUAL

Stoker, H. S. (2011). Biochemistry. Quezon City: C & E Publishing, Inc./Cengage Learning

Bettelheim, F. A., Brown W. H., Campbell M. K. & Farrell, S. O. (2019). Biochemistry.

Quezon City: C & E Publishing, Inc./Cengage Learning.

Campbell, M. K. and Farrell, S. O. (2015). Biochemistry (8th ed.).

Stamford CT: Brooks Cole/Cengage Learning Asia Pte Ltd.

Villarante, N. R. (2015). Laboratory Manual in Biochemistry.

Bacoor City: St. Dominic College of Asia.

SUGGESTED REFERENCES

Garrett, R.H. & Grisham, C.M. (2013). Biochemistry (5th ed.).

Page 36 of 41
 Australia: Brooks Cole/Cengage Learning.

Harvey, R.A. & Ferrier, D. R. (2011). Lippincott’s Illustrated Reviews: Biochemistry (5th ed.).

Philadelphia: Lippincott Williams & Wilkins.

Landesberg, J. (2012). Basic Laboratory Experiments for General, Organic and Biochemistry.

Australia: Brooks Cole/Cengage Learning.

SUGGESTED READINGS (E-JOURNALS)

Garcia-Villegas, R., Camacho-Villasana, Y., Shingu-Vazquez, M., Cabrera-Orefice, A.,Uribe-Carvajal, S. &

Perez-Martinez, X. (2017). The Cox1 C-Terminal Domain is a Central Regulator of Cytochromecoxidase

Biogenesis in Yeast Mitochondria. Journal of Biological Chemistry, 292(26),10912-10925. Retrieved from

http://www.jbc.org/content/292/26.toc.

Kargari, M., Tavassoli, S., Avan, A., Ebrahimi, M., Azarpazhooh M., Asoodeh,R. & Parizadeh, S. (2017).

Relationship Between Serum Anti-Heat Shock Protein 27 Antibody Levels and Obesity. Clinical

Biochemistry, 50(12), 690-695. Retrieved from http://www.sciencedirect.com/science/journal/00099120.

Nishita, M., Satake T., Minami Y. & Suzuki A. (2017). Regulatory Mechanisms and Cellular Functions of Non-

Centrosomal Microtubules. The Journal of Biochemistry, 162(1), 1-10. Retrieved from

https://academic.oup.com/jb/issue.

Ranjitkar, P., Greene D., Baird G., Hoofnagle, A. & Mathis P. (2017). Establishing Evidence-Based Thresholds

Page 37 of 41
 and Laboratory Practices to Reduce Inappropriate Treatment of Pseudohyperkalemia. Clinical

Biochemistry, 50(12), 663-669. Retrieved from http://www.sciencedirect.com/science/journal/00099120.

Togashi, S., Takahashi, K., Tamura, A., Toyota, I., Hatakeyama, S., Komatsuda, A. & Itoh H. (2017). High Dose of

Antibiotic Colistin Induces Oligomerization of Molecular Chaperone HSP90. The Journal of

Biochemistry, 162(1), 27-36. Retrieved from https://academic.oup.com/jb/issue.

COURSE REQUIREMENTS

1. Periodical Examinations (Major Exams) - Preliminary, Midterm, and Final

2. Quizzes
3. Class Participation/Recitation/Seat works/Assignments
4. Research Papers/Projects/Written Reports/Schematic Diagrams

GRADING SYSTEM

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 Lecture Grade Laboratory Grade
Major Exam – 40% Major Exam – 40%
Quizzes – 20% Schematic Diagram – 20%
Recitation/Seat works/Assignments – 20% Participation/Performance – 20%
Research/Project – 20% Group Activity/Written Report – 20%

The Semestral Grade (SG) is obtained by getting the sum of 33% of the Prelim Grade (PG), 33% of the Midterm Grade (MG), and
34% of the Final Grade (FG) for the course.

SG = (PG x 0.33) + (MG x 0.33) + (FG x 0.34)

To pass the course, the student should get a Semestral Grade of 75%.

CASSROOM POLICIES
1. On Attendance
A student who incurs more than the maximum allowable absences, i.e. 20% of the required school days, shall be
reported/referred to the Program Chair. He will then determine whether or not the student should be given a failing grade and
given no credit for the course or subject, for reasons considered valid and acceptable to the school. In case the student is
allowed to continue, he shall be held responsible for coping up with the lessons and assignments and for taking examinations
when applicable.

3. On ID

Students should always wear their ID inside the campus.

4. On Cleanliness

Students should help in the maintenance of cleanliness and orderliness inside the classroom.

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CONSULTATION HOURS

Thirty (30) minutes for every class period will be allotted for consultations with the students.

Prepared by: / Date: Endorsed by: / Date:

LUISITO S. SALTING JR., RCh, DR. MARY NELLIE T. ROA

Faculty Member Dean, School of Nursing and Allied Health Studies

Page 40 of 41
Reference Reviewed by: / Date: Approved by: / Date:

MS. LAILA ARIATE MLS

Librarian
Reviewed by: / Date:
: DR. NILDA W. BALSICAS
CHRISTIAN S. TU RN, MAN Vice President for Academics and Research
Nursing Program Coordinator

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