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CVS-Pharma Past Paper Solution

cvs

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0% found this document useful (0 votes)
61 views27 pages

CVS-Pharma Past Paper Solution

cvs

Uploaded by

Dipendra Sah
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
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OR ACH UGH eos ay Bp. pe ‘. 7 Treats Oral, Fenctdepaan Fg Scanned with CamScanner Captopril, 4 an _ongiotendin. coneniny —2neyme (ACE) inhibitor, that ~ prevent the Comendtg__0 —Angiotentin, cee eel “ONd__Anhibik the breakeven _Of bradykinin. Clinical waed _ - 7 pS —__> Lrypertentivg__ hi > Heat faitue__| Rowe. 2? Draveter fOr Toucty fst | = Cough” — _ — WedeMa 2. Hyperkal emia, dae => __Renol_\mpoinmenh | mea gt ane onsta — ara - | 3 —_________CBig_kataung _ —| a4. Prema hala Sapte iy Shocts: _| An___Ondogenoins_precurtoe of norepinephrine Y _Wikh _rmultsple date elated _e-feckt, _@rmutoter CX Band clepaminergie _ceceprees. ___ SR ee dlopamiasene @ ___Offects ie. enhanced __Splanchaic_and “nel _ ___ blow _Flow__and__hente_maintedn_tenal shinies | even _io_hypovalemic_conditita. x A __modenate_close, Positive inotropic effect. (84) ond rene _inureased Cardiac output. ——Ait_high diode. showoi_-odrenergic_effect ANd _COUsel HestedemetsctO9 _Votoconspictteq —__ Qnd__hence__Malotora_1 ____Therefire_Dopamite A sed in_hypovolemie_ shock, ___ Ultdeshar. vet Scanned with CamScanner 5.2 See _ aang 3¢h) = 6 >See geno BCbo)——— ve _Nawerte ebfect Of - - Adwere effectt Of 2 AY Hydtotorine 2. Lepus-like erytnomatus — 2° __Tachycaretign seeotingy od ——\i7- fenoldopam 2 Tae cardia, headache oad —@= tat — Flushing Also crease inbraoctilor pretinr.. x Hi odium_nipmpmeses, 2 Excessive hypolenatod. —— es ___shocr. a - eo ts Mino» hirsuitismy.jn_demate. ee |v Gionethidine » Severe ortnothatic_hypotentinn @ stand Serial Aye fun com. ge ——-LBrg—kat-2ung)——— = % _Rottunale for Clinical ute! of raeiny _yperbd chotrs—in—maq—On A. ra dopa: Merny ldepa i —ano%-ogonis_that_\ ® ——f_converted tu —_meHyinarepinephtine_tentity _*= 4 climinith adrenergic _outtiow ream the cnc S> ——And_4\_iMed_-for_Management_of hryperteaiug = ——_lo_pregnanyy, mm = CLippiey a ——4Therapeutic_user_of _Motiyt dopo _ancl_otoncdine: ~~ | ee Monogement._of_hypertensron —to_pregnaney. ~ LO} 3) mets os > Management _¢ pire tina cao , nal tease cheat — (Lappin) * — oS Mee ~ Scanned with CamScanner — Jv. Advette effect? of: ————— Oe Sot elopa 2 —___—— aS. aired mental _cancenpaties - p> Nightmares, mentel_chepneatton, Vertigo 2 Development —ot—a_Positive Coombs 424 __ ___( Hemoly enema) ———b» Clonidine: an ————— > Comtipatinn— Dye mou — > _Dwoweined 2 _Hypoienuton Coun. ___— oe ——— AB; Kat zung Lippi AL Role of _ Prozocin- PH __ Prozocin, being —an—alpha1Coty)_agontsr, ___improve_urine_«flow—clue_to_partiel__contractten—| ____ reyertal _tf_Smenth—_mustle —(orpactiog —in i entonged_prastate—and—in_the bladder baste _ G LB Katong) a 2_Dizzines_____ is i _ 2 > headache go 2 _frtnnshatic_hypotendinn— _ (Lippin) __ See @: No £3: (Ch), Scanned with CamScanner i 35 __Blectmiytic _ Hic_aclvente_ottecte of Inop climes ix Mypoxatemia Aix Nypomagneremia fe — Ny Hypocatcemra.- Cout tay percatcemin.n Notume- —— —_=depteted. Patient) —Metabptic_acduene effects of loop aliuretict: iy Hypokatemic. metabolic _alkatocit ai Eh ee i lel la ininla er rer Lema. = Capping Kaizung) — 9 co he Acute. ge a Te Duce oe side ok gonna j_____Congattive glaucoma: pe « wlic_ditwre-tion alter Starting fore & ____40_that_toater leaves cell and__reduces i ______intacelluar_volume,__mannitel _droiias_oater_ - dvom__ humour. Compartment —And__neduced _ intaccutar_predcure. — “= a —CBig_Katzung) ___® -_s ~~ ~ Ly olmotic_dit Lune tich i> Mdonitol_ . Wy Q\ycerta ‘ Trocombidte /——“Raionale of thet use ta whocanial Space 7 2c Pying, _letimn: s Fey can rede _btain_Nolume_anel_ ieee “crt festa oer _tnte_the bleed fi Citar Kateugyy * Scanned with CamScanner Nijebpoe of attivnwt...C021 Channel blienun Ca charnel blockers block phe Ledype Ca2* channel in heat and decremse 146 a Content tility and le kype COPt channe in _ Nedcels, deere. Clawing. Sidi ..tav4dle..of Yood vestels and detreosing 4Arled portphonas —_tumran. (Lippin Kaley) 19. Adverse. effect! of Cart channed balun: » flushing : ti Dizzidesr. 2 —Wi7 Headache. = 1’ Hypotendion — gre ir pelreral atone, WY, ON | vir Gingiuad_hs Platio a Yeeros i e ere Lipping: tninikatzug) 00. Clinieal_urer_of Ca2+ channel block. on: (Ba kaka ) .— Guorithidine, ae "4 7 : ares Intertores —totth arnine _sebeaste. “and. _ ____!epocer_ “Dovepaeptrine 4 Abedichea. Cinco ge; Adverse ebldcle —— E > Seyere OrHho atic kypptenitoe —___ Seal Ae une jee Z xi (big katzurgs gait Na ible Sallis ithe he i bree Scanned with CamScanner oe a = _«€ LA Rationale tet incl Angina, Niteng)ycerineteteater Nitric oxide CNo} Ach — wt” activate Manyly! cy Clase and Ameracied the learel of c@Me. = 5 Lncreated <6. P_taitl_clephouproglale | MyouineLagit Chain dne\_hence _Cautor relaxatta 6 Of Smovth muucted of Comnary Vedcels._ - “ind Catuted —_increaded Lived to_hear On Alo cautet Nenodilation hence cletreaded WOM load on heats Uainikatzuny) Adverse effects of ni nglyeetn! Hy Wekycardig iy Ohad atic. hyporend’on Aii> Headache LHhmobbing o LUNe_of nlbeng iy cexine in ————— b—RE ON OQ Nativnale__fos —the Clinical vised _of_mettyldopa: & See @:Ny RS See__@- Nv. LY dp caine hock Sodmm channels and aldo heen phate x _reprlarization ond decrease the duraten_of_action_potentral.__ Uses =f? Venbicwon techy corde ND oe a Nenttienar Fire fprrina NT_ Storm. Scanned with CamScanner Zt. Zildenafel = Sildenafil. blocks. phos idicheroses thigh: jncrenue CAMP level ard Nene Used. to Freak Cre cile _clytunction. —..__. Sildenatil__porentiotes the acktoes ONwarped Uns-eol foe _Ongina and Severe hypprsbenaien and __o_fera myocardial infarction: - Sildenafil can —ollo _be.Usetul tr pastectiog ; Hote. ON. Coraltac remodelt ‘@ ahsen Theme and __repesfudton _Sildenofil ts is sued. bo Acco puimenay __ hyperteniion—. - _ — "(Big Katong) ee Scanned with CamScanner of —2h- Quinine ——Miechanam ef Action: —Quintdine, a clase 14 antiarrhythmic, blocks Natchannel_, and slower conductton velocity And Pacemaker rate, Prrlengt. actor potentral duration and _ditsociates from Ing Channel ~__TR_adie shows direct depressant_etfeck— -2_£A Nade and AN node. oo Ce feck: PUPPPTARAAAATE > Excessive QT ioterval prolongation —_____ —__>_ Induction _of _tontactet_de_pointer_arrhytnmios, ____ fatracardiac tontethy ie eee __> Cinchonam{ headache, di2zmede tinnitus) iP DA rpe b Prone ix Regutation of Lytaolic Cat con¥entrabten: a By inhibiting the _No*/K* ATPade, _¢ is da in. tauecs_ the Gy of the _myoyte gq +y_attively _pump_Nat-frnm_the com, _Thi 5 inreaset tree Nat ture the cell so + ___ nee: Na*/ca exchanger _caill_oot_voom and < = ~ hence _inhracyteplosimic_Coet _oaitl_inenease ___ | Cauuing nerecued —carcltac —cnbactility, Scanned with CamScanner * wh ed _ Contact eda : = . —Digoria- ingrepslel the forte o¢ Cardliac contraction, ~ Causing Carcliac output te more_clotely tespmple_ that of the normal heart. ____—— e _ Digoxin stows _concluctia relouy —— Av node, making 1 useful for. ’ Abra » = Se _iii7_Newrphormonal inhibition, ———— ™~ > low-dose digoxin inhibits Sym pathetic activation =~ = _____Wwith_minimal_©rt (_on_Careliag COntaa tility. — (Lippi aes ___4y_Dyponin _tnhibike Not/At enchange by Not/KtA! —_tiy_The_ concentration of —inhaceltutar Nat focreasels _ andthe concentration —grod tent —acrost_the— a Membrane clecrenses._ = — = ___ ily Tnereoted Natt decreases the _olrivi BR force = forthe Nott/cat* encharyen So there t¢_dlecieaserd | tran port _of Ca?+ _into_the extracellular space. CLippin _| 31. Adverw effect! of- Digontn % ficthy Hamas Boel a \ y Naureas Nomi 9 — ; Diarrhea _ f “| ®@ IY Cordiog ormett Thentment_of Digoug tonicity: . i7_Conrection of. k*_or_Mag** leticteny. _ Si Apticucchyg thi ic_druga a 7 —i2_Digowa— Ontibedies (Far fregments, Digitind). et ——CiAtatKatoungs Scanned with CamScanner ~Wy_ Chronic Antfamatic—heo ‘hoa Failure. Antal Fittation : NZ Nodal artutnmiat atic_leve],~ digoda. wae “thow. j——Porayympatmomimeric effect: © - 2 Effective _refractoypertsd of abial muscle Fc. reduced — but that _of AV node —#C__ increased. — => Conductton. Nelocihy_in_atrfal Musee ee SnCneaded but —“thot_in AV node 7 ae "Plinikete tt ga - eee hy coudlia_ael__ ———Contractiliby _prbcuved tay _nitrate-ncluced_hygoteniin.— |__|V_Nibrater prevent any ony vadeep : [giced_igettens ae 7 Mitake peuedt iranian. teft_vorbiater predure or preloael Medutting rem the > eee nN = ive_inobopic_efteck 4 —Pieduced hy B=blockert._S WY Nitraket_ond_Pelisckert_topn_neduse myocar _____ 0 _foquiremente »__Nitmber And p-blockerr both _inyreate_sub-eadocandial dood Flows ___ OT C S\tetedhare-nety ~ Scanned with CamScanner 3B _Dyugs uted in pamaysma)._ Supa lan — aclycardin CPD _—_—_— 1 Elecainide (Claas 1¢ -antianrtytamic) > Blockt Not -ond—k* Channel. exapami 4 anti Henmic) a eee plese od ned tn - rear and clos _~S4_ode- aut cy __| 3 and AV nodal__conductien Nelouby, > | Ne ——_—_-decreaset_cowdiac —Contrachibiy- —_______— tii Adennune ——————___________— > Ackvabet— inward__echitier T+ aed __- Blocks _Ca2+ Current G4 well earns a Complete AN oekade Se {Big Katwag) —____ 36 Dawgs tox Atrial _-beleets _Fitmilation: eee Procainamide (_Gyrrouy 149. . Uiz_Propranoto|—(_Gyrroup_2)_______ Ui D=Cotatol_( Groups). = ___twy Ebuiinde (Grouped) vy Dotehime (Group 2 ee __© Koteunga, —__— a OR | 7 » Profanenone iy Metoprolol _____iii_frmindorone + pofetiltde —_________ iwy_ Diltiazem _| Se Drange, es ages aa (Lippin) en 3% “Cee G.nto ee a ee ‘Scanned with CamScanner - c S & i Ness _of -bigous +o.abial_§ Abate: The _parauyn npatnomimetic cannot = = —Agitoln Weducat the _conducha Nelocity oo ————inereate_the Yehadoy pertedl _of the AV.nede__ 60 that Ventricular cate ic _Conpolled pi Haio_ et Compatible it ebfserea BING -and_¥e Ejection... ey lee Coin kateung) 29: fee Qo. 3Z. 40 Dwg _ysed tp. brent sil_t moderate, 2 Blox Net) ck tranipsster_in_clivtedt ee on Dluted_tubule __ctne|_Caousos fired, Reduce lady pute and_lente treat —3 ———hypertenicn W Provacin (% Locker) i> Selective bloc |} __CecePter _On_predpheral alegcula_ ie_dilation and reclueet_:p. iy Clon Line and_tne oe ee os Argenta Tepes y Car Channel blocked Scanned with CamScanner j tL. See __G -nto. 40 to Cellunas jarget_#f 1% action. of flurotomid es > Nat-K* 2¢(7 transporter. bhiek @icecling —limb_of _Leop. of Henle. Advere effec: urnemide : _Hypoyolemia_ iz ok alemia 1. yy __eypomagnevem Hypemuridem’® — — 2 is (Brg Kai2ung) Mechanrim of _actidn of Leop diane fed: By inhibits Nat Kt 2 c= hanporper_to ad NCH Adtending —limb_ofloop.of- _Heale, they cause marked increase i9___Nacl_excretido, __Some_k*-Wiasting, Urinary cart and. ig?t excretion __and—-hypokalemic_.metabolic_alalodn. rt myet of top _diwmetel a Purngemizl - > Tortemiale_ __ = Bumetanide 2 Ethauynic acid, pee (Brg. Katou ¢ - 1q_--peatmen: ayes inhalation —of—amy Ojpite followed degree necessary to... hemove_A_sjynificaat: amountof cyanide — rom. Hochwme._oxtdade~ TUNG Q~Codium +hiruttate)s Ohich converts Scanned with CamScanner ja Bo pometneg lobe toto MedulHng from tepstir ' +e_thipyjandie_and_methemogidétn : f-——Thinganate i & lea? touc than yatitle_ = —Ond_& excreted the_ Kida ee —_Hydionacobatami®d cons ARE ab : |_4U5* Ho e-Locker te helpéul_in- aavbytamiad: -—____ B= eel tab blocking, — —_Py_recepten__on_ a v >» 4g. “Precaution “before. or A\CE inhibits therapy: » iy Potassium level must be joer and s __K* cupplemenk_ 2 ae —dliuretiel____ ~» Should bre tuted _$___—_—_—_-—— » iy, Serum creatinine levelé Ghould alto be ~ Monitored. — tw “Patient. Showd_not—be-of Second or ~ Abid trimester of —pregnan oe a : oh | ~C2* channel! blowing -ogenks aan Ph henylalkylamined =—— 7 \erapamil. _ SZ Benzodiazepines — $< ______ _Dtlttazem rs pyridines __> Nifedipine > Armtodipine (Lappin 2 by Sheek _pf_Co®* channel_Llockers “on_skeletal Mile | ee Skeletal _muide #<_nok_depreaved by __ ____Ca®t channel_blouker because tt Lobel = ____Whaelar—_powk__of _¢ Calcturty_supperh -Rxitation=Conhacifre_couplivgy —aud_dowin'd_ : rept animembrane—Catctum influ _ — a — Kateueg Scanned with CamScanner TANASE Bh. Nitvate_ aren p_reatments _ {won ADT), a rc Svein “Houta. es ———__Nibitel_ in watrmrent_of ( yoate pina 2 See = No. Ay. ee BB. see _Q.no fo. * es 53: Rationale dur ude of LS Lsep_ _dturercs like Furetemme_ Ore the dime of Chote fre treatment ~ }______of _ pulmonary. “echera __lbecaute oF —tneir__#* Tapicd onset of action. Clappioy “Thioztde diuretieg: ol -__ > Wydyochtempthtaende Ss Chlorthatidtene => _ On\ovthiaride S| a Metvlazene. Clinical sot i_Hypertenaton— 7 taild heart failure “aiiz_Nephmnithtags = = — te Nepingen drab =| Scanned with CamScanner + Diwwetiet__Yhot_inhibit sbeci¢ic re A » ys : {ronspos Mechanremls —--___._— » 2 » » mA conagetrin (SotLte {nhibite) 0g inhibits Not/Glucere_Cotranepsrer_ in Pet - pene Vy_Purecemide_(.Leop- “gio : D_{nhibts Nat/kt/2cl= fran portec in — Ascending. [mb of Loop. of Henle. iH drochlowothtaride_(Thiarideclitinetica) ~ inhilei Nat/cl”_framdparter_in_D¢T.__ WY Armitortde_C Potauium-cparing—cliuretion ny Glee epic Ao chante Cattecting twoulel- fave epfeck of Thi of Thiazides 2 DKalemic_metabo! netabplic_alkolorie’ yperuricem . y | Peet Omg: sips gd mira od em fy ie ng —HypercCat ceem. ————— : ea Ay _effecht of Diuretic: vy = ae psttal_hoemedynantic Qtnormalitiel. iz ane renal _neab(oxptiva of Spdiwm_and_toater_ Renal __perfudie and ER Prepreative y decline. toto tas Slideshare. nek) Scanned with th CamScanner Be>. o» Clase T anvarrhyzhmier. ( B-blockero ‘Cla = ee ~~ Prppranolol__—____- —— - Uy _Egmotol . _ ee (ota ———Clinicol_tes , —____— yy Angina — ir thenva : ~ tile Hy perteniten iys _Thyrptoxicocie vy) Tremor wy ¢ Fright wii ripe _ a E ——s Ckat2ungd) _ ty_earrt_failure____ 2 _ ii Putmonay_ede a HY _Sewerehypertensron_ — yy ger acamnie entL toaicitrels ke0 @.No. 49 Dt: ay. REK_Of adminslering short octing, Oval_nvfedipine fim the “treatment op U hypemensien: > Rcrepteal—esek ern ocoraal ieee on Mosaliry. @ 3 > sperific indication fmr_adihinsthabina.of 2 Chron. 2_Rapry Aten _ pede coder dj Scanned with CamScanner jqcativa. dupthe ody 19 ‘he. tb. ty Aseat her _hypemlensiva iy ‘Lifertyte meadunes Suth ad salt vestricrioe Ond Weight. reduction. iz. Diuretics (4) phtazide HiS7_ACE inhibitors 6% ARB ivy Madodilatox ( Ca? channel blocker) - or GtmpathoPlegict (a P-blocked ce both, yer oe - Fr Kateung) __by Tonic Tonic_elfeckt of eta Polastinm. syacigg Uh Diwretiet: 4y_. eee neta bali Acidost. —— (Big Kateurg— 9. Ratinnale fa inhibi ina. : “diners pati D Because “A ae ton _rrnprrove— Introrencl__hemodynamicl, toith —clecrented_ 7 —flomemiar efferent arjectrlor_resMance cand _ _ Mulan —Teduction__of ___intra, lomennar—capinary — —Preature. And odo they dimind)__ proteinuria, ond Gabilive renal funtion, thats why - ol owe_Useal i _dTalsehie _patrent it, - uced _ renol _functiba. . i Katong) See Adutepte effect? of — a i9___ ts. Q No, 3Cby._ nH Scanned with CamScanner 60 (a). Thentment _ to_Swbiide the pain aad _ prevent further atiotk of Angina: poses A To_ Siibstele the acute Pains oo a 2 Sublinguo! glycan > nophy | an —anel “teanicermal_ __>_Prppranolo_( B-blocker) _ pa > Nerapami), Dilthazem, Nitfecipm Cocalo Channel _blockery ?__Ranolazine. o —Kataung) int iy ‘Bleed in eee _ GIS coe @ no. fie 68. (0). fe tueL ots Beat cone wae ‘ Mono therapy tn Areat —tgfastin bf_the oldman pe Slenanv: I ip joehde dimrety —. 7 Apgfovenain feceptor blockers inhibitor _ we Calcium _Channel_blocker. Jp Sakai J Hed group Ot drugs can os that ~ Ore vid _in_dianeric patient ith bupertendions YY ACE tohibpon : 1iy_Prngipteniin_eceptor Glocker 7 esc_thetn _Mechanium see Q:No. 53. Scanned with CamScanner ~63: an “Beneticial etiegs of Px blockers: iy Decreated heart rate: BP-and___- Contract li Which checreade —— My ocarai P Oy regiatremenk_ot Test_and_exercve. Lower heart rate coo __ivy _ B-Vockerxs_cle create _mertality of —______ fatten heant._failure err ___] —_—_Tecent_Myoconelia.|_i nfarctfoo.—___ Deletertous effec of. _P-blochert : © Increade_in_end- diastolic volume _| ____rnd__an__incneade_in_ejection_time,_incrade _ Myoconelial__¢ oe Reg. ubrement yy ___| Drugs _Cormbined “wi Ha __their _lelelerinus_oftectt: —_ > Nitatet_can_ batance_ the: dleleterbut _ deck of -blocker, Bin kateung) ____ _ Rereasret nitric ontele the action of ALDHg and NO will commsst activate — aulsis guanylyl Gyclase that Conver GTP te_ COMP. Tncreaded. level fel COMP — Catet _clepherphoyflattoa Of. “Myoun Aight Chaty and hence _relaxatten_Of Cmonth Muscle Of _ Yed.ooll - A2_CQ2*— channel blocKens _____ > Block_L-type cath channel s _ _mudde__cind__heart.,decneanel__jrvpace ier __ Cae _and__reduce__conractfon__and_heace___ een ty deert_angino of &Hets = Block_.G¢mpathebic_efteckt on heart ___and bleed pressure and ole _reducet____ __renin _releaue Causing fluid _log¢_____ ini kate Be blockers are_conatndicated 1 sgseatepaat CMT Keteung) Scanned with CamScanner Hy Reblen_taclycarata —-64-Cinical Aedicotiony of Loop diuretics: 17 fruste pulmonary edema; [Tee Aiurtic keae ee chun 7 Ouerload and reducer flutd volume. and _hences_vevemet ~Pulmenary ectema. )——y7_ekyperbalemia : i Lowp_diuretie enhance urinary a enoretron_of Kl Wi Atute rened_ailure: = =“ panna of urine flow and__ehhance. ket excretion, ~~ ~ tin acute. renal failue S p_——tvy_ Pron __ovrerdodes Loop aiucobcl Ore useful i 0 amy = om] Si -_____toue_ingeston __of bromide, fluoride and, ~ Limb_of ae of__ttenle. 7 ____See_Adveme_effeck of Isop diuretic E oO. @.No. 49 ee - 7 (Big Kateung) 68: See Q-Nno Cob. eo -__ ___ Tsetse __obrumbies - 69. see @ No. 30a) + 3¢b) - Th raeile_dturetin wot couse : yoeriipidemia _Co-enormal liptd_protilo. So - ini: Katong 8 rr | \ ia Scanned with CamScanner

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