Terapi diabetes militus tipe 2 di RS
Terapi A Terapi B Terapi C Terapi D
Biaya (rp) 200k 300k 150k 50k
Outcome Penurunan 50 30 65 45
GDA
(mg/dL)
ACER : cost / effect
A = 200k/50 = 4.000 pembanding
B = 300k/30 = 10.000
C = 150k/65 = 2.307,69
D = 50k/45 = 1.111,1
ICER : delta cost / delta effect
B = 300k -200k / 30 -50 = -5k (dominant -)
C = 150k – 200k / 65 – 50 = -3,33k
D = 50k – 200k / 45 – 50 = 30k (trade off+)
Dominant pasti cost effective
Cost effective belum tentu dominan
Terapi C paling cost effective dalam menurunkan gula darah acak
Kalau C dihapus, terapi A trade off terapi D, tetapi lebih cost effective daripada terapi D
Terapi Diabetes Mellitus tipe 2 di RS
Terapi A Terapi B Terapi C Terapi D
Biaya (rp) 200k 300k 150k 50k
Outcome Penurunan 50 30 65 45
GDA
(mg/dL)
Penurunan 2 3 1 2
HbA1c
Lama 7 5 3 6
perawatan
di rs
ACER : cost / effect
(GDA)
A = 200k/50 = 4.000 pembanding
B = 300k/30 = 10.000
C = 150k/65 = 2.307,69
D = 50k/45 = 1.111,1
(HbA1c)
A = 200k/2 = 100k
B = 300k/3 = 100k
C = 150k/1 = 150k
D = 50k/2 = 25k
Lama perawatan di RS
A = 200k/7 = 28,5k
B = 300k/5 = 60k
C = 150k/3 = 50k
D = 50k/6 = 8,3k
ICER :
GDA :
B = 300k -200k / 30 -50 = -5k (dominant -)
C = 150k – 200k / 65 – 50 = -3,33k
D = 50k – 200k / 45 – 50 = 30k (trade off+)
HbA1c :
B = 300k -200k / 3-2 = 100k
C = 150k – 200k / 1-2 = 50k
D = 50k – 200k / 2-2 = tak terhingga
Lama perawatan di Rs
B = 300k -200k / 5-7 = 100k
C = 150k – 200k / 3-7 = 12,5k
D = 50k – 200k / 6-7 = 150k
Gambar diagram sendiri
Yang lama perawatan semakin ke kanan semakin tidak efektif (titik tengah 7, kekanan
otomatis 8,9,10,11) semakin k kiri efektif (titik tengah 7, kekiri otomatis 6,5,4,3)
CUA
QALY = semakin tinggi semakin bagus
DALY = semakin tinggi semakin jelek
QALY = year of life x utility
Contoh : Rating scale
Dari umur 20-25 utilitas 1
25-35 0,7
0,5
0,4
Rating scale = (5x1) + (10 x 0,7) + (rentang tahun x 0,5) + (rentang tahun x 0,4) = ....
semakin tinggi semakin bagus
Standart Gamble
Harus ada komunikasi, harus ada tanya jawab, cenderung angka lebih rendah atau kadang2
lebih tinggi dari pada rating scale
Caranya : kondisi sekarang responden (STEP A)
Time Trade Off
Cara bertanya berbeda: ngomong dalam sisi waktu (x/t)
CBA
Cost benefit = benefit - cost
Cost benefit ratio = benefit / cost = 1 artinya, benefit = cost
benefit / cost >1 , benefit lebih besar