International Journal Dental and Medical Sciences Research
Volume 3, Issue 1, pp 29-30 www.ijdmsrjournal.com ISSN: 2582-6018
Etiological Study Of Autism and Assessment By ISAA(Indian
Scale For Assessment Of Autism) For Diagnosis Of Autism
Spectrum Disorder In Children at Hi-Tech Medical College and
Hospital,Bhubaneswar
Dr.Gautam Tripathy1Dr.Sasmita Devi Agrawal2Dr.Sidhant Swarup3
Professor, Dept. of Paediatrics, Hi-Tech Medical College & Hospital ,Bhubaneswar
PG resident, Hi-Tech Medical College & Hospital, Bhubaneswar
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Date of Submission: 15-12-2020 Date of Acceptance: 21-12-2020
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BACKGROUND: Autism Spectrum Disorder wordspontaneous (not just echolalia) phrases by 24
(ASD) usually presents in early developmental months and loss of any language or social skills at
period, in children less than 3 years usually with any age[9].
poor social relations, verbal and nonverbal Keywords: Autism Spectrum Disorder; ISAA;
communications and restricted and repetitive Applied Behavioural Analysis; Social
behaviour[1]. The prevalence of ASD is increasing Communication and Interaction
rapidly, especially in urban population of
developed as well as developing nations. I. OBJECTIVE:
According to recent database , Every 1 in 68 To determine the diagnostic validityand
children are diagnosed with autism spectrum accuracy of Indian Scale for Assessment of Autism
disorder, leading to a considerable health care and (ISAA) in children aged 1.5-9 year at high risk of
economic burden on society[2][3].ASD is autism, and to ascertain the level of agreement with
multifactorialCombined interaction of genetic and Childhood Autism Rating Scale (CARS) and
environmental factors has been proposed as the INCLEN(INDT-ASD)[10][11].
possible neuropathogenesis mechanism underlying Design: Diagnostic and Accuracy study
ASD.Recently DSM V criteria have combined Setting: Tertiary-level hospital(Hi-Tech Medical
under a single roof all the autistic disorders College & Hospital)
including Asperger syndrome and pervasive Duration:From Jan 2019 to Aug 2019
developmental disorder-not otherwise Participants: Children aged between 1.5 and 9 year
satisfied[4].Autistic children are more likely to and considered to be at a high risk for autism
have hyperactivity, inattention, sleep abnormalities (delayed development, and age-inappropriate
and epilepsy, as compared to general cognition, speech, social interaction, behaviour or
population.INCLEN(INDT-ASD) tool and ISAA play) were recruited. Those with diagnosed
are commonly used in India for diagnosing and Hearing impairment, Cerebral palsy, Attention
calculating severity of autism for disability deficit hyperactivity disorder or Pervasive
certification in our country[5][6]. The other tools developmental disorders (PDD) were excluded.
for Autism assessment are Childhood Autism
Rating Scale (CARS), Autism Behaviour Checklist II. METHODS:
(ABC), Applied Behaviour Analysis (ABA), M- Eligible children underwent a
CHAT (modified Check List for comprehensive assessment according to assessment
autism)[7][8].Onset of ASD symptoms typically of different parameters of ISAAtool and results
occurs by age 3yr, although symptoms may not were compared to the INCLEN(INDT-ASD) and
fully manifest until school age or later, and some CARS scoring.
research suggests symptoms can emerge between 6
and 18months of age. More severely affected
children are more likely to be identified and
reliably diagnosed at younger ages than milder
cases. Early markers of autism are no babbling by III. RESULT & STATISTICAL
12months, not waving bye-bye by 12 months, no ANALYSIS:
single words by 16 months, no two-
DOI: 10.35629/5252-03012930 |Impact Factorvalue6.18| ISO 9001: 2008 Certified Journal Page 29
International Journal Dental and Medical Sciences Research
Volume 3, Issue 1, pp 29-30 www.ijdmsrjournal.com ISSN: 2582-6018
Out of 39 eligible children attending Sensitivity of ISAA is 90% and Specificity is
Paediatric Neurology OPD between Jan2019 to 77.7%. The Positive predictive value is 0.93 and
Aug2019, 27(69.2%) were Autistic Out of which the Negative predictive value is 0.7as compared to
17(62.9%)/ were Mild Autistic and 10(37.03%) INCLEN-INTD.
were moderately Autistic. From this study the
Result
25.64% No Autism
30.76%
Mild
Moderate
43.58%
IV. CONCLUSIONS: INCLEN Study Group. Indian Pediatr
The reliability and validity of ISAA for 51(5):359-365. Autism 21(3): 368-374.
diagnosis and assessment for severity of Autism is [6]. 16. National Trust Web based Intervention
good. The role of ISAA in 1.5 -9 year old children Resource Centre.Indian Scale for
at high risk for Autism is limited to identifying and Assessment of Autism. Available
certifying Autism at ISAA score of 70. from:www.nationaltrust.co.in. Accessed
Aug 19, 2019.
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DOI: 10.35629/5252-03012930 |Impact Factorvalue6.18| ISO 9001: 2008 Certified Journal Page 30
