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Syllabus Sem4

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128 views21 pages

Syllabus Sem4

Uploaded by

Sudhir roy
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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SEMESTER IV

PT414. PHARMACEUTICAL ORGANIC CHEMISTRY –III (Theory)


45 Hours
Scope: This subject imparts knowledge on stereo-chemical aspects of organic compounds
and organic reactions, important named reactions, chemistry of important hetero cyclic
compounds. It also emphasizes on medicinal and other uses of organic compounds.
Objectives: At the end of the course, the student shall be able to
1. understand the methods of preparation and properties of organic compounds
2. explain the stereo chemical aspects of organic compounds and stereo chemical
reactions
3. know the medicinal uses and other applications of organic compounds
Course Content:

Note: To emphasize on definition, types, mechanisms, examples, uses/applications

UNIT-I 10 Hours

Stereo isomerism
Optical isomerism –
Optical activity, enantiomerism, diastereoisomerism, meso compounds
Elements of symmetry, chiral and achiral molecules
DL system of nomenclature of optical isomers, sequence rules, RS system of
nomenclature of optical isomers
Reactions of chiral molecules
Racemic modification and resolution of racemic mixture.
Asymmetric synthesis: partial and absolute

UNIT-II 10 Hours

Geometrical isomerism
Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems)
Methods of determination of configuration of geometrical isomers.
Conformational isomerism in Ethane, n-Butane and Cyclohexane.
Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for optical
activity.
Stereospecific and stereoselective reactions
UNIT-III 10 Hours
Heterocyclic compounds:
Nomenclature and classification
Synthesis, reactions and medicinal uses of following compounds/derivatives
Pyrrole, Furan, and Thiophene

Relative aromaticity and reactivity of Pyrrole, Furan and Thiophene

UNIT-IV 8 Hours

Synthesis, reactions and medicinal uses of following compounds/derivatives


Pyrazole, Imidazole, Oxazole and Thiazole.
Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of pyridine
Synthesis and medicinal uses of Pyrimidine, Purine, azepines and their derivatives

UNIT-V 07 Hours

Reactions of synthetic importance


Metal hydride reduction (NaBH4 and LiAlH4), Clemmensen reduction, Birch
reduction, Wolff Kishner reduction.
Oppenauer-oxidation and Dakin reaction.
Beckmanns rearrangement and Schmidt rearrangement.
Claisen-Schmidt condensation
Recommended Books (Latest Editions)
1. Organic chemistry by I.L. Finar, Volume-I & II.
2. A text book of organic chemistry – Arun Bahl, B.S. Bahl.
3. Heterocyclic Chemistry by Raj K. Bansal
4. Organic Chemistry by Morrison and Boyd
5. Heterocyclic Chemistry by T.L. Gilchrist
PT416. PHYSICAL PHARMACEUTICS-II (Theory)
45Hours
Scope: The course deals with the various physical and physicochemical properties, and
principles involved in dosage forms/formulations. Theory and practical
components of the subject help the student to get a better insight into various
areas of formulation research and development, and stability studies of
pharmaceutical dosage forms.

Objectives: Upon the completion of the course student shall be able to


1. Understand various physicochemical properties of drug molecules in the
designing the dosage forms
2. Know the principles of chemical kinetics & to use them for stability testing and
determination of expiry date of formulations
3. Demonstrate use of physicochemical properties in the formulation
development and evaluation of dosage forms.
Course Content:
UNIT-I 07 Hours

Colloidal dispersions: Classification of dispersed systems & their general


characteristics, size & shapes of colloidal particles, classification of colloids &
comparative account of their general properties. Optical, kinetic & electrical properties.
Effect of electrolytes, coacervation, peptization& protective action.

UNIT-II 10 Hours

Rheology: Newtonian systems, law of flow, kinematic viscosity, effect of temperature,


non-Newtonian systems, pseudo plastic, dilatant, plastic, thixotropic, thixotropic in
formulation, determination of viscosity, capillary, falling Sphere, rotational viscometers
Deformation of solids: Plastic and elastic deformation, Heckel equation, Stress, Strain,
Elastic Modulus

UNIT-III 10 Hours

Coarse dispersion: Suspension, interfacial properties of suspended particles, settling in


suspensions, formulation of flocculated and deflocculated suspensions. Emulsions and
theories of emulsification, microemulsion and multiple emulsions; Stability of emulsions,
preservation of emulsions, rheological properties of emulsions and emulsion
formulation by HLB method.
UNIT-IV 10Hours

Micromeretics: Particle size and distribution, mean particle size, number and weight
distribution, particle number, methods for determining particle size by different
methods, counting and separation method, particle shape, specific surface, methods for
determining surface area, permeability, adsorption, derived properties of powders,
porosity, packing arrangement, densities, bulkiness & flow properties.

UNIT-V 10 Hours

Drug stability: Reaction kinetics: zero, pseudo-zero, first & second order, units of basic
rate constants, determination of reaction order. Physical and chemical factors influencing
the chemical degradation of pharmaceutical product: temperature, solvent, ionic strength,
dielectric constant, specific & general acid base catalysis, Simple numerical problems.
Stabilization of medicinal agents against common reactions like hydrolysis & oxidation.
Accelerated stability testing in expiration dating of pharmaceutical dosage forms.
Photolytic degradation and its prevention
PT 496. PHYSICAL PHARMACEUTICS- II (Practical)
3 Hrs/week

1. Determination of particle size, particle size distribution using sieving method


2. Determination of particle size, particle size distribution using Microscopicmethod
3. Determination of bulk density, true density and porosity
4. Determine the angle of repose and influence of lubricant on angle of repose

5. Determination of viscosity of liquid using Ostwald’s viscometer


6. Determination sedimentation volume with effect of different suspendingagent
7. Determination sedimentation volume with effect of different concentration of
single suspending agent
8. Determination of viscosity of semisolid byusing Brookfield viscometer
9. Determination of reaction rate constant first order.
10. Determination of reaction rate constant second order
11. Accelerated stability studies

Recommended Books: (Latest Editions)


1. Physical Pharmacy by Alfred Martin, Sixth edition
2. Experimental pharmaceutics by Eugene, Parott.
3. Tutorial pharmacy by Cooper and Gunn.
4. Stocklosa J. Pharmaceutical calculations, Lea & Febiger, Philadelphia.
5. Liberman H.A, Lachman C., Pharmaceutical Dosage forms, Tablets, Volume-1 to 3,
Marcel Dekkar Inc.
6. Liberman H.A, Lachman C, Pharmaceutical dosage forms. Disperse systems, volume 1,
2, 3. Marcel Dekkar Inc.
7. Physical Pharmaceutics by Ramasamy C, and Manavalan R.
PT 418. PHARMACOLOGY-I (Theory)
45 Hrs
Scope: The main purpose of the subject is to understand what drugs do to the living
organisms and how their effects can be applied to therapeutics. The subject covers the
information about the drugs like, mechanism of action, physiological and biochemical
effects (pharmacodynamics) as well as absorption, distribution, metabolism and excretion
(pharmacokinetics) along with the adverse effects, clinical uses, interactions, doses,
contraindications and routes of administration of different classes of drugs.
Objectives: Upon completion of this course the student should be able to
1. Understand the pharmacological actions of different categories of drugs
2. Explain the mechanism of drug action at organ system/sub cellular/
macromolecular levels.
3. Apply the basic pharmacological knowledge in the prevention and treatment of
various diseases.
4. Observe the effect of drugs on animals by simulated experiments
5. Appreciate correlation of pharmacology with other bio medical sciences
Course Content:
UNIT-I 08 hours
1. General Pharmacology
a. Introduction to Pharmacology- Definition, historical landmarks and scope of
pharmacology, nature and source of drugs, essential drugs concept and routes of
drug administration, Agonists, antagonists( competitive and non competitive), spare
receptors, addiction, tolerance, dependence, tachyphylaxis, idiosyncrasy, allergy.
b. Pharmacokinetics- Membrane transport, absorption, distribution, metabolism and
excretion of drugs .Enzyme induction, enzyme inhibition, kinetics of elimination
UNIT-II 12 Hours

General Pharmacology
a. Pharmacodynamics- Principles and mechanisms of drug action. Receptor theories
and classification of receptors, regulation of receptors. drug receptors interactions
signal transduction mechanisms, G-protein–coupled receptors, ion channel receptor,
transmembrane enzyme linked receptors, transmembrane JAK-STAT binding
receptor and receptors that regulate transcription factors, dose response
relationship, therapeutic index, combined effects of drugs and factors modifying
drug action.
b. Adverse drug reactions.
c. Drug interactions (pharmacokinetic and pharmacodynamic)
d. Drug discovery and clinical evaluation of new drugs -Drug discovery phase,
preclinical evaluation phase, clinical trial phase, phases of clinical trials and
pharmacovigilance.
UNIT-III 10 Hours
2. Pharmacology of drugs acting on peripheral nervous system
a. Organization and function of ANS.
b. Neurohumoral transmission, co-transmission and classification of neurotransmitters.
c. Parasympathomimetics, Parasympatholytics, Sympathomimetics,sympatholytics.
d. Neuromuscular blocking agents and skeletal muscle relaxants (peripheral).
e. Local anesthetic agents.
f. Drugs used in myasthenia gravis and glaucoma

UNIT-IV 08 Hours
3. Pharmacology of drugs acting on central nervous system
a. Neurohumoral transmission in the C.N.S. special emphasis on importance of
various neurotransmitters like with GABA, Glutamate, Glycine, serotonin,
dopamine.
b. General anesthetics and pre-anesthetics.
c. Sedatives, hypnotics and centrally acting muscle relaxants.
d. Anti-epileptics
e. Alcohols and disulfiram

UNIT-V 07 Hours
3. Pharmacology of drugs acting on central nervous system
a. Psychopharmacological agents: Antipsychotics, antidepressants, anti-anxietyagents,
anti-manics and hallucinogens.
b. Drugs used in Parkinsons disease and Alzheimer’s disease.
c. CNS stimulants and nootropics.
d. Opioid analgesics and antagonists
e. Drug addiction, drug abuse, tolerance and dependence.
PT 498. PHARMACOLOGY-I (Practical)
4Hrs/Week
1. Introduction to experimental pharmacology.
2. Commonly used instruments in experimental pharmacology.
3. Study of common laboratory animals.
4. Maintenance of laboratory animals as per CPCSEA guidelines.
5. Common laboratory techniques. Blood withdrawal, serum and plasma separation,
anesthetics and euthanasia used for animal studies.
6. Study of different routes of drugs administration in mice/rats.
7. Study of effect of hepatic microsomal enzyme inducers on the phenobarbitone sleeping
time in mice.
8. Effect of drugs on ciliary motility of frog oesophagus
9. Effect of drugs on rabbit eye.
10. Effects of skeletal muscle relaxants using rota-rod apparatus.
11. Effect of drugs on locomotor activity using actophotometer.
12. Anticonvulsant effect of drugs by MES and PTZ method.
13. Study of stereotype and anti-catatonic activity of drugs on rats/mice.
14. Study of anxiolytic activity of drugs using rats/mice.
15. Study of local anesthetics by different methods
Note: All laboratory techniques and animal experiments are demonstrated by simulated
experiments by software’s and videos
Recommended Books (Latest Editions)
1. Rang H. P., Dale M. M., Ritter J. M., Flower R. J., Rangand Dale’s
Pharmacology,.Churchil Livingstone Elsevier
2. Katzung B. G., Masters S. B., Trevor A. J., Basic and clinical pharmacology, Tata Mc
Graw-Hill
3. Goodman and Gilman’s, The Pharmacological Basis of Therapeutics
4. Marry Anne K. K., Lloyd Yee Y., Brian K. A., Robbin L.C., Joseph G. B., Wayne A.
K., Bradley R.W., Applied Therapeutics, The Clinical use of Drugs, The Point Lippincott
Williams & Wilkins
5. Mycek M.J, Gelnet S.B and Perper M.M. Lippincott’s Illustrated Reviews-
Pharmacology
6. K.D.Tripathi. Essentials of Medical Pharmacology, JAYPEE Brothers Medical
Publishers (P) Ltd, New Delhi.
7. Modern Pharmacology with clinical Applications, by Charles R.Craig& Robert,
8. Ghosh MN. Fundamentals of Experimental Pharmacology. Hilton & Company,
Kolkata.
9. Kulkarni SK. Handbook of experimental pharmacology. Vallabh Prakashan,
PT 412.PHARMACOGNOSY AND PHYTOCHEMISTRY I (Theory)
45 Hours
Scope: The subject involves the fundamentals of Pharmacognosy like scope, classification of
crude drugs, their identification and evaluation, phytochemicals present in them and their
medicinal properties.

Objectives: Upon completion of the course, the student shall be able


1. to know the techniques in the cultivation and production of crude drugs
2. to know the crude drugs, their uses and chemical nature
3. know the evaluation techniques for the herbal drugs
4. to carry out the microscopic and morphological evaluation of crude drugs

Course Content:

UNIT-I 10 Hours
Introduction to Pharmacognosy:
(a) Definition, history, scope and development of Pharmacognosy
(b) Sources of Drugs – Plants, Animals, Marine &Tissue culture
(c) Organized drugs, unorganized drugs (dried latex, dried juices, dried extracts, gums and
mucilages, oleoresins and oleo- gum -resins).

Classification of drugs:
Alphabetical, morphological, taxonomical, chemical, pharmacological, chemo and sero
taxonomical classification of drugs

Quality control of Drugs of Natural Origin:


Adulteration of drugs of natural origin. Evaluation by organoleptic, microscopic, physical,
chemical and biological methods and properties.

Quantitative microscopy of crude drugs including lycopodium spore method, leafconstants,


camera lucida and diagrams of microscopic objects to scale with camera lucida.

UNIT-II 10 Hours
Cultivation, Collection, Processing and storage of drugs of natural origin:
Cultivation and Collection of drugs of natural origin
Factors influencing cultivation of medicinal plants.
Plant hormones and their applications.
Polyploidy, mutation and hybridization with reference to medicinal plants

Conservation of medicinal plants

UNIT-III 07 Hours
Plant tissue culture:
Historical development of plant tissue culture, types of cultures, Nutritional requirements,
growth and their maintenance.
Applications of plant tissue culture in pharmacognosy.
Edible vaccines
UNIT IV 10 Hours
Pharmacognosy in various systems of medicine:
Role of Pharmacognosy in allopathy and traditional systems of medicine namely, Ayurveda,
Unani, Siddha, Homeopathy and Chinese systems of medicine.

Introduction to secondary metabolites:


Definition, classification, properties and test for identification of Alkaloids, Glycosides,
Flavonoids, Tannins, Volatile oil and Resins

UNIT V 08 Hours
Study of biological source, chemical nature and uses of drugs of natural origin containing
following drugs
Plant Products:
Fibers - Cotton, Jute, Hemp
Hallucinogens, Teratogens, Natural allergens

Primary metabolites:
General introduction, detailed study with respect to chemistry, sources, preparation,
evaluation, preservation, storage, therapeutic used and commercial utility as Pharmaceutical
Aids and/or Medicines for the following Primary metabolites:
Carbohydrates: Acacia, Agar, Tragacanth, Honey
Proteins and Enzymes : Gelatin, casein, proteolytic enzymes (Papain, bromelain,
serratiopeptidase, urokinase, streptokinase, pepsin).
Lipids(Waxes, fats, fixed oils) : Castor oil, Chaulmoogra oil, Wool Fat, Bees Wax
Marine Drugs:
Novel medicinal agents from marine sources
PT 492. PHARMACOGNOSY AND PHYTOCHEMISTRY I (Practical)
4 Hours/Week
1. Analysis of crude drugs by chemical tests: (i)Tragacanth (ii) Acacia (iii)Agar (iv)
Gelatin (v) starch (vi) Honey (vii) Castor oil
2. Determination of stomatal number and index
3. Determination of vein islet number, vein islet termination and paliside ratio.
4. Determination of size of starch grains, calcium oxalate crystals by eye piece
micrometer
5. Determination of Fiber length and width
6. Determination of number of starch grains by Lycopodium spore method
7. Determination of Ash value
8. Determination of Extractive values of crudedrugs
9. Determination of moisture content of crudedrugs
10. Determination of swelling index andfoaming

Recommended Books: (Latest Editions)


1. W.C.Evans, Trease and Evans Pharmacognosy, 16th edition, W.B. Sounders & Co.,
London, 2009.
2. Tyler, V.E., Brady, L.R. and Robbers, J.E., Pharmacognosy, 9th Edn., Lea and
Febiger, Philadelphia, 1988.
3. Text Book of Pharmacognosy by T.E. Wallis
4. Mohammad Ali. Pharmacognosy and Phytochemistry, CBS Publishers&
Distribution, New Delhi.
5. Text book of Pharmacognosy by C.K. Kokate, Purohit, Gokhlae (2007), 37th Edition,
Nirali Prakashan, New Delhi.
6. Herbal drug industry by R.D. Choudhary (1996), Ist Edn, Eastern Publisher, New
Delhi.
7. Essentials of Pharmacognosy, Dr.SH.Ansari, IInd edition, Birla publications, New
Delhi, 2007
8. Practical Pharmacognosy: C.K. Kokate, Purohit, Gokhlae
9. Anatomy of Crude Drugs by M.A. Iyengar
MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY
(Formerly West Bengal University of Technology)
B.PHARM Syllabus
(Effective from 2021-2022 Admission Session)

PT 413 MEDICINAL CHEMISTRY – I (Theory)


45 Hours
Scope: This subject is designed to impart fundamental knowledge on the structure, chemistry
and therapeutic value of drugs. The subject emphasizes on structure activity relationships of
drugs, importance of physicochemical properties and metabolism of drugs. The syllabus also
emphasizes on chemical synthesis of important drugs under each class.
Objectives: Upon completion of the course the student shall be able to
1. understand the chemistry of drugs with respect to their pharmacological activity
2. understand the drug metabolic pathways, adverse effect and therapeutic value of
drugs
3. know the Structural Activity Relationship (SAR) of different class of drugs
4. write the chemical synthesis of some drugs
Course Content:

Study of the development of the following classes of drugs, Classification, mechanism of


action, uses of drugs mentioned in the course, Structure activity relationship of selective class
of drugs as specified in the course and synthesis of drugs superscripted (*)
Only structure and Chemical name of the highlighted compounds need to be discussed.

UNIT- I 10 Hours

Introduction to Medicinal Chemistry


History and development of medicinal chemistry

Physicochemical properties in relation to biological action


Ionization, Solubility, Partition Coefficient, Hydrogen bonding, Protein binding, Chelation,
Bioisosterism, Optical and Geometrical isomerism.
Drug metabolism
Drug metabolism principles- Phase I and Phase II.
Factors affecting drug metabolism including stereo chemical aspects.

UNIT- II 10 Hours
Drugs acting on Autonomic Nervous System Adrenergic

Neurotransmitters:
Biosynthesis and catabolism of catecholamine.
Adrenergic receptors (Alpha & Beta) and their distribution.

Sympathomimetic agents: SAR of Sympathomimetic agents


Direct acting: Nor-epinephrine, Epinephrine, Phenylephrine*, Dopamine,
Methyldopa, Clonidine, Dobutamine, Isoproterenol, Terbutaline, Salbutamol*,
Bitolterol, Naphazoline, Oxymetazoline and Xylometazoline.
 Indirect acting agents: Hydroxyamphetamine, Pseudoephedrine,
Propylhexedrine.
MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY
(Formerly West Bengal University of Technology)
B.PHARM Syllabus
(Effective from 2021-2022 Admission Session)

 Agents with mixed mechanism: Ephedrine, Metaraminol.

Adrenergic Antagonists:
Alpha adrenergic blockers: Tolazoline*, Phentolamine, Phenoxybenzamine,
Prazosin, Dihydroergotamine, Methysergide.
Beta adrenergic blockers: SAR of beta blockers, Propranolol*, Atenolol, Esmolol,
Metoprolol, Labetolol, Carvedilol.

UNIT-III 10 Hours

Cholinergic neurotransmitters:

Biosynthesis and catabolism of acetylcholine.


Cholinergic receptors (Muscarinic & Nicotinic) and their distribution.

Parasympathomimetic agents: SAR of Parasympathomimetic agents


Direct acting agents: Acetylcholine, Carbachol*, Bethanechol, Methacholine,
Pilocarpine.
Indirect acting/ Cholinesterase inhibitors (Reversible & Irreversible):
Physostigmine, Neostigmine*, Pyridostigmine, Edrophonium chloride, Tacrine
hydrochloride, Ambenonium chloride, Isofluorphate, Echothiophate iodide,
Parathione, Malathion.
Cholinesterase reactivator: Pralidoxime chloride.
Cholinergic Blocking agents: SAR of cholinolytic agents
Solanaceous alkaloids and analogues: Atropine sulphate, Hyoscyamine sulphate,
Scopolamine hydrobromide, Homatropine hydrobromide, Ipratropium bromide*.
Synthetic cholinergic blocking agents: Tropicamide, Cyclopentolate hydrochloride,
Clidinium bromide, Dicyclomine hydrochloride*, Glycopyrrolate, Methantheline
bromide, Benztropine mesylate, Orphenadrine citrate, Biperidine hydrochloride,
Procyclidine hydrochloride*, Tridihexethyl chloride, Ethopropazine hydrochloride.

UNIT- IV 08 Hours

Drugs acting on Central Nervous System


A. Sedatives and Hypnotics:

Benzodiazepines: SAR of Benzodiazepines, Chlordiazepoxide, Diazepam*,


Oxazepam, Lorazepam, Alprazolam, Zolpidem
Barbiturtes: SAR of barbiturates, Barbital*, Phenobarbital, Mephobarbital,
Amobarbital, Pentobarbital, Secobarbital
Miscelleneous:
Amides & imides: Glutethmide.
Alcohol & their carbamate derivatives: Meprobomate, Ethchlorvynol. Aldehyde &
their derivatives: Triclofos sodium, Paraldehyde.
MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY
(Formerly West Bengal University of Technology)
B.PHARM Syllabus
(Effective from 2021-2022 Admission Session)

B. Antipsychotics
Phenothiazines: SAR of Phenothiazeines - Chlorpromazine hydrochloride*,
Triflupromazine, Thioridazine hydrochloride, Trifluoperazine hydrochloride.
Ring Analogues of Phenothiazines: Chlorprothixene, Thiothixene, Loxapine
succinate, Clozapine.
Fluro buterophenones: Haloperidol, Droperidol, Risperidone.
Beta amino ketones: Molindone hydrochloride.
Benzamides: Sulpieride.

C. Anticonvulsants: SAR of Anticonvulsants, mechanism of anticonvulsant


action
Barbiturates: Phenobarbitone, Methabarbital.

Hydantoins: Phenytoin*, Mephenytoin, Ethotoin Oxazolidine


diones: Trimethadione, Paramethadione Succinimides:
Phensuximide, Methsuximide, Ethosuximide*

Urea and monoacylureas: Phenacemide, Carbamazepine*


Benzodiazepines: Clonazepam
Miscellaneous: Primidone, Valproic acid , Gabapentin, Felbamate

UNIT – V 07 Hours
Drugs acting on Central Nervous System
General anesthetics:
Inhalation anesthetics: Halothane*, Methoxyflurane, Enflurane, Isoflurane, Desflurane.
Ultra short acting barbitutrates: Methohexital sodium*, Thiamylal sodium, Thiopental
sodium.
Dissociative anesthetics: Ketamine hydrochloride.*
Narcotic and non-narcotic analgesics
Morphine and related drugs: SAR of Morphine analogues, Morphine sulphate, Codeine,
Meperidine hydrochloride, Loperamide hydrochloride, Fentanyl citrate*, Methadone
hydrochloride*, Pentazocine, Levorphanol tartarate.
Narcotic antagonists: Nalorphine hydrochloride, Naloxone hydrochloride.
Anti-inflammatory agents: Sodium salicylate, Aspirin, Mefenamic acid*, Meclofenamate,
Indomethacin, Sulindac, Tolmetin, Zomepriac, Diclofenac, Ketorolac, Ibuprofen*, Naproxen,
Piroxicam, Phenacetin, Acetaminophen, Antipyrine, Phenylbutazone.
MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY
(Formerly West Bengal University of Technology)
B.PHARM Syllabus
(Effective from 2021-2022 Admission Session)

PT-493 MEDICINAL CHEMISTRY – I (Practical)

4 Hours/Week
I Preparation of drugs/ intermediates

1 1,3-pyrazole

2 1,3-oxazole

3 Benzimidazole

4 Benztriazole

5 2,3- diphenyl quinoxaline

6 Benzocaine

7 Phenytoin

8 Phenothiazine

9 Barbiturate
MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY
(Formerly West Bengal University of Technology)
B.PHARM Syllabus
(Effective from 2021-2022 Admission Session)

II Assay of drugs

1 Chlorpromazine

2 Phenobarbitone

3 Atropine

4 Ibuprofen

5 Aspirin

6 Furosemide

III Determination of Partition coefficient for any two drugs

Recommended Books (Latest Editions)


1. Wilson and Giswold’s Organic medicinal and Pharmaceutical Chemistry.
2. Foye’s Principles of Medicinal Chemistry.
3. Burger’s Medicinal Chemistry, Vol I to IV.
4. Introduction to principles of drug design- Smith and Williams.
5. Remington’s Pharmaceutical Sciences.
6. Martindale’s extra pharmacopoeia.
7. Organic Chemistry by I.L. Finar, Vol. II.
8. The Organic Chemistry of Drug Synthesis by Lednicer, Vol. 1-5.
9. Indian Pharmacopoeia.
10. Text book of practical organic chemistry- A.I.Vogel.
MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY
(Formerly West Bengal University of Technology)
B.PHARM Syllabus
(Effective from 2021-2022 Admission Session)
IV Assay of drugs

7 Chlorpromazine

8 Phenobarbitone

9 Atropine

10 Ibuprofen

11 Aspirin

12 Furosemide

V Determination of Partition coefficient for any two drugs

Recommended Books (Latest Editions)


1. Wilson and Giswold’s Organic medicinal and Pharmaceutical Chemistry.
2. Foye’s Principles of Medicinal Chemistry.
3. Burger’s Medicinal Chemistry, Vol I to IV.
4. Introduction to principles of drug design- Smith and Williams.
5. Remington’s Pharmaceutical Sciences.
6. Martindale’s extra pharmacopoeia.
7. Organic Chemistry by I.L. Finar, Vol. II.
8. The Organic Chemistry of Drug Synthesis by Lednicer, Vol. 1-5.
9. Indian Pharmacopoeia.
10. Text book of practical organic chemistry- A.I.Vogel.
MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY
(Formerly West Bengal University of Technology)
B.PHARM Syllabus
(Effective from 2021-2022 Admission Session)

HU 481 COMMUNICATION SKILLS (Theory)


30 Hours
Scope: This course will prepare the young pharmacy student to interact effectively with
doctors, nurses, dentists, physiotherapists and other health workers. At the end of this course
the student will get the soft skills set to work cohesively with the team as a team player and
will add value to the pharmaceutical business.
Objectives:
Upon completion of the course the student shall be able to
1. Understand the behavioral needs for a Pharmacist to function effectively in the
areas of pharmaceutical operation
2. Communicate effectively (Verbal and NonVerbal)
3. Effectively manage the team as a teamplayer
4. Develop interviewskills
5. Develop Leadership qualities andessentials

Course content:

UNIT–I 07Hours

 Communication Skills: Introduction, Definition, The Importance of Communication,


The Communication Process – Source, Message, Encoding, Channel, Decoding,
Receiver, Feedback,Context

 Barriers to communication: Physiological Barriers, Physical Barriers, Cultural


Barriers, Language Barriers, Gender Barriers, Interpersonal Barriers, Psychological
Barriers, Emotionalbarriers

 Perspectives in Communication: Introduction, Visual Perception, Language, Other


factors affecting our perspective - Past Experiences, Prejudices, Feelings,Environment

UNIT–II 07Hours

 Elements of Communication: Introduction, Face to Face Communication - Tone of


Voice, Body Language (Non-verbal communication), Verbal Communication, Physical
Communication

 Communication Styles: Introduction, The Communication Styles Matrix with example


for each -Direct Communication Style, Spirited Communication Style, Systematic
Communication Style, Considerate CommunicationStyle
MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY
(Formerly West Bengal University of Technology)
B.PHARM Syllabus
(Effective from 2021-2022 Admission Session)
UNIT–III 07Hours

 Basic Listening Skills: Introduction, Self-Awareness, Active Listening, Becoming an


Active Listener, Listening in DifficultSituations

 Effective Written Communication: Introduction, When and When Not to Use Written
Communication - Complexity of the Topic, Amount of Discussion’ Required, Shades of
Meaning, FormalCommunication
 Writing Effectively: Subject Lines, Put the Main Point First, Know Your Audience,
Organization of theMessage

UNIT–IV 05Hours

 Interview Skills: Purpose of an interview, Do’s and Dont’s of aninterview

 Giving Presentations: Dealing with Fears, Planningyour Presentation, Structuring Your


Presentation, Delivering Your Presentation, Techniques ofDelivery

UNIT–V 04Hours

 Group Discussion: Introduction, Communication skills in group discussion, Do’s and


Dont’s of group discussion
MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY
(Formerly West Bengal University of Technology)
B.PHARM Syllabus
(Effective from 2021-2022 Admission Session)

HU482 COMMUNICATION SKILLS (Practical)

2 Hours / week
The following learning modules are to be conducted using Wordsworth English
®

language lab software

Basic communication covering the following topics

Meeting People

Asking Questions

Making Friends

What did you do?

Do’s and Dont’s

Pronunciations covering the following topics

Pronunciation (Consonant Sounds)

Pronunciation and Nouns

Pronunciation (Vowel Sounds)

Advanced Learning

Listening Comprehension / Direct and Indirect Speech Figures

of Speech

Effective Communication

Writing Skills

Effective Writing

Interview Handling Skills

E-Mail etiquette

Presentation Skills
MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY
(Formerly West Bengal University of Technology)
B.PHARM Syllabus
(Effective from 2021-2022 Admission Session)

Recommended Books: (Latest Edition)


1. Kulbhushan Kumar, Effective Communication Skills, Khanna Publishing House
2018 (AICTE Recommended Textbook 2018)
2. Basic communication skills for Technology, Andreja. J. Ruther Ford, 2nd Edition,
Pearson Education,2011
3. Communication skills, Sanjay Kumar, Pushpalata, 1stEdition, Oxford Press,2011
4. Organizational Behaviour, Stephen .P. Robbins, 1stEdition, Pearson,2013
5. Brilliant- Communication skills, Gill Hasson, 1stEdition, Pearson Life,2011
6. The Ace of Soft Skills: Attitude, Communication and Etiquette for success, Gopala
Swamy Ramesh, 5thEdition, Pearson,2013
7. Developing your influencing skills, Deborah Dalley, Lois Burton, Margaret, Green
hall, 1st Edition Universe of Learning LTD,2010
8. Communication skills for professionals, Konar nira, 2ndEdition, New arrivals –
PHI, 2011
9. Personality development and soft skills, Barun K Mitra, 1stEdition, Oxford Press,
2011
10. Soft skill for everyone, Butter Field, 1st Edition, Cengage Learning india pvt.ltd,
2011
11. Soft skills and professional communication, Francis Peters SJ, 1stEdition, McGraw
Hill Education, 2011
12. Effective communication, John Adair, 4thEdition, Pan MacMillan,2009
13. Bringing out the best in people, Aubrey Daniels, 2ndEdition, Mc Graw Hill,1999

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