Chapter 2: Tutorials

Overview Create a ChemDraw Document:

1. Start ChemDraw.
The tutorials are designed to teach you the
fundamental drawing techniques available in 2. From the File menu, choose Save As.
ChemDraw. Before you begin, you may want to 3. Type tut1.cdx in the appropriate text box.
review “Conventions” on page 10 to familiarize 4. Select a folder in which to save the file.
yourself with the terminology used in the tutorials.
5. Click Save.
You may also want to use your Quick Reference
Card while you perform the tutorials. 6. From the View menu, choose Show General
Toolbar.
ChemDraw automatically checks for correct
7. From the View menu, choose Show Info
chemical syntax as you draw. If ChemDraw finds a
Window.
potential problem, a red box is displayed around the
erroneous object. The red box is displayed on The Info window appears and displays drawing
screen only and does not print. parameters as you draw.
To disable the automatic warning on a specific
object:
• Right-click the object and deselect Display
Warnings.

Tutorial 1: Reaction
Schemes
In this tutorial, you will draw the following
(simplified) reaction scheme:

O O
OH

OH
2-propanone 4-hydroxy-4-methyl-2-pentanone
2 moles 1 mole
2-propanone Rx 60%

ChemDraw 9 Tutorials • 31
Tutorial 1: Reaction Schemes
 8. Click the Object menu and make sure there is a
NOTE: The angle used when clicking to add bonds is
check mark next to the Fixed Lengths and Fixed
controlled by the Chain Angle setting in the Drawing
Angles commands. If either command is not
Settings dialog box in the File menu. If this bond angle
checked, select it.
cannot be established, the next smaller and logical bond
Administrator

angle is used.

Add a third bond:

1. Continue pointing to the atom shown below.
.

NOTE: Applying fixed lengths and fixed angles enables

you to create structures with consistent bond lengths and
2. Click the atom to add a bond.
angles. The fixed length dimension is set in the Drawing
Settings dialog box. The fixed angle dimension increments Change a single bond into a double bond:
angles by 15 degrees.
1. Point to the atom shown below and hold the
mouse button down.
Create a bond:
1. Click the Solid Bond tool .
2. Position the pointer (+) anywhere in the
document window and click.
The bond is extended to its fixed length at a 2. Drag as shown below over the existing single
30-degree angle. bond. Release the mouse button.

Add a second bond:

1. Point to the right atom of the bond. Add labels to the structure:
1. Point to the atom shown below.

2. Click the atom to add a bond.

A second bond is drawn, forming a 120-degree
angle between the bonds.

32•Tutorials CambridgeSoft
Tutorial 1: Reaction Schemes
 2. Double-click the atom. The hand pointer with a plus sign indicates that
you are in the duplication mode of a selection
tool.

isobutene
w/textbox
100%

3. Type an uppercase O in the text box that

appears. 4. Drag the Selection Rectangle to the right.
.

4. Close the text box by doing one of the A copy of the structure appears as you begin
following: drag. The original structure remains in its
position. Release the mouse button when the
• Click in an empty area of the window.
copy is clear of the original.
• Click another tool.
Next, you duplicate a structure and then create NOTE: When you create a copy as shown above you can
another structure from the duplicate. drag it anywhere in the document window. If you want the
copy to remain aligned with the original, hold Shift while
Duplicate the structure: dragging.
1. Click the Lasso tool .
The last structure drawn is automatically Modify the duplicated structure:
selected. 1. Click the Solid Bond tool .
2. Point over the Selection Rectangle.
2. Point, in the copied structure, to the atom
shown below and click.
O

3. Press and hold Ctrl or Option.

ChemDraw 9 Tutorials • 33
Tutorial 1: Reaction Schemes
 Add several bonds to a single atom: Align the structures:
1. Point to the atom shown below. 1. Select the structures.

O 2. On the Object menu, point to Align, and then

choose T/B centers.
Administrator

You structures should appear as shown below.

O O
2. Click the atom three times, allowing a pause
between each click.

NOTE: If you click too fast, the click is interpreted OH

either as a double-click, which opens a text box or a In the following steps, you use a different method
triple-click, which duplicates your last atom label. for selecting structures and then separate the
structures to make room for an arrow.
O 1. Click the Marquee tool .

NOTE: Alternatively, you can select the Lasso tool

and hold Alt or Option to use the Marquee tool.

The last object drawn is selected.

Create an atom label using HotKeys. HotKeys are
keys on your keyboard that are linked to specific Drag the selection to make room for an arrow:
atom labels. For more information about HotKeys, • Press Shift to maintain the alignment of the
see “Labeling Atoms with HotKeys” on page 87. structure and drag the Selection Rectangle to
the right.
1. Point to the atom shown below.

Add arrows to the reaction scheme.

2. Type O or o.
1. Click the Arrow tool to display the Arrow
O palette.

NOTE: The triangle in the lower right corner of the

Arrow icon indicates it contains a palette.
OH
2. Holding the mouse button down, move the
When you use HotKeys that represent a single mouse to the palette title bar, then release the
element, the correct number of hydrogen atoms is mouse button.
added to the label.
The palette becomes a floating tool bar. Drag
the palette to the location you want.

34•Tutorials CambridgeSoft
Tutorial 1: Reaction Schemes
 3. Click the third arrow from the left in the top Use the Text tool to add line formula or other
row. captions for representing reagents and reactions.
Insert text in the drawing:
1. Click the Text tool .
2. Point above the arrow. A text insertion point
appears as shown below.
SelectArrow
150 dpi O O

4. After the arrow is selected, release the mouse

button.
OH
NOTE: The arrow you choose from the palette
3. Click to create a text box.
becomes the default arrow type. To change the arrow
type, display the arrow palette and select the arrow type O O
you want.

Draw the arrow you selected: OH

4. Type OH.
1. Point after the first structure and hold down
the mouse button. O O

O O

OH

OH NOTE: If you want to realign the caption, select a

2. Drag the Arrow to the length you want. Release selection tool and drag the caption.
the mouse button.
Add a charge symbol using the specialized symbols
O O available in the Chemical Symbols tool palette:
1. Click the Chemical Symbol tool .
OH
NOTE: A red box appears around the OH label
NOTE: If you need to change the length (or the angle indicating an error, i.e. that you haven’t added the charge yet.
relative to the X-axis) of the arrow:
1. Hold Shift and point to the arrowhead 2. Holding the mouse button down, select the
(a highlight box appears when you are circled negative charge symbol shown
pointing correctly). below, then release the mouse button.
2. Drag the arrowhead to the length (and angle)
you want.
SelectMinus

ChemDraw 9 Tutorials • 35
Tutorial 1: Reaction Schemes
 3. Point to the center of the OH label. Moving the Use the Text tool to create a caption containing the
cursor slightly right or left will cause either the name and amount of reactant, and then center the
O or the H to be selected. caption under the structure.
1. Click the Text tool .
Administrator

O O
OH
2. Point below the first structure.

OH O
4. With the H selected, drag the charge symbol
around the atom to the desired position.

O O
OH

3. Click to create a text box. The default cursor is

OH
flush left.
Objects added from the Chemical Symbols palette
are automatically associated with the structure they O
are closest to.
Some objects, such as arrows, are not associated
automatically. You can manually group objects
using the Group command. You can then select the
grouped objects to manipulate or move them
together. 4. From the Text menu, choose Centered.

To group objects: O
1. Click a Selection tool, the Lasso or
Marquee tool.
2. Hold Shift and click the arrow, the OH caption,
and the charge symbol.

The cursor moves to the center of the text box.

Type the caption:
The Shift key allows you to add objects to a
selection without deselecting other objects. 1. Type 2-propanone.

NOTE: If you click a selected object while holding O

Shift, that object is deselected.

3. From the Object menu, choose Group.

NOTE: You can select individual objects within a 2-propanone

group by clicking them.

36•Tutorials CambridgeSoft
Tutorial 1: Reaction Schemes
 2. Press the Enter or Return key to insert a new If your captions are not aligned properly beneath
line. the structures you can move them using a selection
tool.
O
1. Click a Selection tool (Lasso or Marquee).
The text box is automatically selected because
it is the last object drawn.

2-propanone NOTE: The object that is automatically selected is set in the

Preferences dialog box.

3. Type 2 moles. 2. Press the Left or Right Arrow key to center

the caption beneath its structure. This method
O
maintains the alignment created by the Tab key.
To complete the drawing, add a shadowed box
around the scheme:
1. Click the Drawing Elements tool .
2-propanone
2 moles 2. Select the shadowed box from the palette of
drawing elements.
Create an aligned caption for the other structure.
1. Press the Tab key to create another Text box
that is aligned adjacent to the first.
SelectRectangle 150 dpi
O

3. Point to the upper left corner of the reaction

2-propanone scheme. Hold the down the mouse button and
2 moles drag diagonally downward to the right to draw
the box.
NOTE: You can use the Tab key in the caption mode
of the text tool to create multiple aligned captions with pentanone 60%
the same font, font size, style, and justification as the
previous caption.
O O
OH
2. Type 4-hydroxy-4-methyl-2-pentanone, press
the Enter or Return key, and then type 1 mole. OH
2-propanone 4-hydroxy-4-methyl-2-pentanone
2 moles 1 mole

ChemDraw 9 Tutorials • 37
Tutorial 1: Reaction Schemes
 Save and close the document: Delete an atom and its bonds from the ring:
1. From the File menu, choose Save. 1. Click the Eraser tool .
Your document is saved. 2. Point to the atom shown below.
Administrator

2. From the File menu, choose Close.

Tutorial 2: Drawing
an Intermediate
In this tutorial you will draw the following
3. Click the atom.
intermediate structure starting from a ring and then
add arrows with customized shapes using the Pen
tool.

O-
OH

NOTE: You can delete a bond individually by pointing at

the center of the bond and clicking.
Create a new ChemDraw document: You can also drag the eraser to make multiple deletions.
1. From the File menu, choose New Document.
2. From the File menu, choose Save As.
Add a bond:
3. Type tut2.cdx in the appropriate text box. 1. Click the Solid Bond tool .
4. Select a folder in which to save the file. 2. Point to the atom shown below.
5. Click Save.

Draw a ring:
1. Click the Cyclohexane Ring tool .
2. Point in the document window. The 3. Click to add a bond.
Cyclohexane cursor appears.
3. Click to add a ring.

38•Tutorials CambridgeSoft
Tutorial 2: Drawing an Intermediate
Add second and third bonds: 2. Drag diagonally downward over the existing
bond to create a double bond.
1. Point to the atom shown below and click to add
another bond.

2. Add a third bond by dragging to make sure it Change the orientation of the double bond:
has the desired orientation: 1. Point to the center of the double bond.
a. Continue pointing to C4.

2. Click the bond twice to move the second line to

b. Hold the mouse button and drag diagonally
the outside.
upward toward the right.
The bond moves to the inside on the first click
and to the outside on the second click
.

c. When the bond is oriented, release the

mouse button to deposit the bond.
NOTE: You can move a double bond by clicking it
Create a double bond: when a bond tool is selected. The cursor corresponding
1. Point to the atom shown below. to the bond tool that is selected appears.

Add an atom label:

1. Point to the atom to label shown below.

ChemDraw 9 Tutorials • 39
Tutorial 2: Drawing an Intermediate
 2. Double-click the atom to open a text box. 3. Point near the double bond where you want to
indicate the start of electron flow.

O-
Administrator

OH

3. Type O and then type “-”.

4. Drag downward and to the left. Release the
mouse button.
O-
OH

Label an atom with OH:

1. Point to the atom shown below.

The hand with a “+” cursor indicates that you

are in the editing mode of the Pen tool.
5. Position the cursor where you want the
arrowhead to appear.
2. Double-click the atom to open a text box. O-
O- OH

3. Type OH. 6. Drag upward to create a curve segment.

Next you will add an arrow that is not included in
the arrow palette to indicate electron flow. O-
OH
To create a customized arrow using the Pen tool.
1. Click the Pen tool .
2. From the Curves menu, choose Arrow at
End.

40•Tutorials CambridgeSoft
Tutorial 2: Drawing an Intermediate
Refine the shape of the arrow: Tutorial 3: Using Rings
1. Point to the handle pointing away from and to
In this tutorial you will draw more complex
the right of the curve. This is a tangent handle
structures by using rings.
that controls the tangent of the curve that it
touches. O

CH

2. Drag the handle upward to the right to make

the arrowhead point more inward.
Open a new ChemDraw document:
1. From the File menu, choose New Document.
2. From the File menu, choose Save As.
3. Type tut3.cdx in the appropriate text box.
4. Select a folder in which to save the file.

3. Press Esc when you are finished. 5. Click Save.

4. Create additional arrows as described above to Create a ring:

complete the intermediate as shown below.
1. Click the Cyclohexane Ring tool .
-
O 2. Point in an empty area of a document window.
OH

3. Click to add a ring.

NOTE: If you want to magnify the entire document so you

can see arrows or other objects that are in small places, choose
Magnify from the View menu.
Fuse a second ring to the first:
Save and close the document: 1. Point to the center of lower right bond in the
1. From the File menu, choose Save. ring.
2. From the File menu, choose Close.

ChemDraw 9 Tutorials • 41
Tutorial 3: Using Rings
 2. Click to fuse another ring. 2. Click to fuse another ring.
Administrator

Fuse a third ring:

1. Point to the bond shown below.
Remove atoms and their bonds from the ring using
the Eraser tool:
1. Click the Eraser tool .
2. Point to the atom shown below.

2. Click to fuse another ring. Your document

should contain the structure shown below.

A highlight box appears on the atom to be

removed.
3. Click to delete the atom and its bonds.
Fuse a fourth ring:
1. Point to the bond shown below.

42•Tutorials CambridgeSoft
Tutorial 3: Using Rings
 4. Click each of the atoms shown below to delete 3. Drag upward to draw a double bond.
the bonds.

Add another double bond:

1. Point to the bond shown below.

The resulting structure is shown below.

2. Right-click, point to Double, and then choose

Plain.

Realign the double bond so it is centered:

Add double bonds to the structure: 1. Point to the center of the upper double bond.

1. Click the Solid Bond tool .

2. Point to the atom indicated below.

2. Right-click, point to Bond position, and then

choose Centered.

ChemDraw 9 Tutorials • 43
Tutorial 3: Using Rings
 Add a carbon atom label: Save and close the document.
1. Point to the atom shown below. 1. From the File menu, choose Save.
2. From the File menu, choose Close.
Administrator

Tutorial 4: Fischer
Projections
This tutorial demonstrates creating a Fischer
projection of glucose (shown below) by drawing a
linear series of bonds. You can also create the same
2. Press the c key on your keyboard. “c” is a
drawing using a template.
Hotkey assigned to the atom label C.
The CH atom label appears with the correct CHO

number of hydrogen atoms. HFischer OH

Add an oxygen atom label to complete the Glucose

HO70% H
structure:
H OH
1. Point to the atom shown below.
H OH

CH CH 2 OH

Create a document from a template by opening the

appropriate document template:
1. From File menu, point to Open Special, and
then choose ACS Document 1996.
The new document created is based on a Style
2. Press the o key on your keyboard. “o” is a Sheet or Stationery Pad.
Hotkey assigned to the atom label O.
NOTE: These special documents allow you to have pre-
O
configured settings for different tasks. In this example, the
CH ACS template provides the required settings for structures to
be published in all ACS journals:
• One-column layout (Page Setting)
• Bonds with a Fixed length of 0.2 inches
(Drawing Setting)
• Atom Labels in 10 point Arial or Helvetica font (Text
Setting)

2. From the File menu, choose Save As.

3. Type tut4.cdx in the appropriate text box.

44•Tutorials CambridgeSoft
Tutorial 4: Fischer Projections
 4. Select a folder in which to save the file. 3. Repeat step 1and step 2 three times to draw a
5. Click Save. total of five bonds.

Draw the first bond:

1. Click the Solid Bond tool .
2. Point in the document window. Drag
downward vertically to draw the first bond.

Add a second bond:

1. Point to the lower atom.

NOTE: When you drag the pointer along the length of the
bonds, the pointer alternates between an arrow and a cross.
2. Drag downward to draw the second bond. The arrow indicates you are pointing over the center of a
bond, and the cross indicates you are pointing to an atom.

Add horizontal bonds to the second atom in the

string of bonds you created:
• Point to C2 and click the atom to add a
perpendicular bond.

ChemDraw 9 Tutorials • 45
Tutorial 4: Fischer Projections
 Add a horizontal bond in the opposite direction: 2. Continue pointing to C3 and click the atom to
• Continue pointing to C2 and click the atom to add a perpendicular bond in the opposite
add a perpendicular bond in the opposite direction.
direction.
Administrator

3. Repeat step 1 and step 2 for the fourth (C4)

and fifth (C5) atoms.
Add bonds to the next three carbon atoms:
1. Point to C3 and click the atom to add a
perpendicular bond.

46•Tutorials CambridgeSoft
Tutorial 4: Fischer Projections
Add labels to C1 and C6: 3. Point to C6.

1. Point to C1.

4. Double-click C6 to create a text box, then type

2. Double-click C1 to create a text box, then type
CH2OH.
CHO.

CHO

5. Type Esc to deselect the label.

6. Add the H and OH labels:

ChemDraw 9 Tutorials • 47
Tutorial 4: Fischer Projections
 1. Point to the atom shown below. 4. Label the remaining atoms by typing o to label
them with OH. The result should appear as
CHO shown below.
Administrator

CHO

H OH
Fischer
H OGlucose H
70%
H OH

H OH

C H 2O H

CH2OH View the basic properties of the structure you drew

2. Type h to label the atom using the Hotkey label and paste the information into your document:
for hydrogen.
1. Click a selection tool to automatically select the
CHO last structure drawn. If the structure is not
selected, double-click the structure.
H
2. From the View menu, choose Analysis
Window.
The Analysis window appears. You can drag
the window to any position.

CH2OH

3. Repeat step 2 for the remaining hydrogen

atoms shown below.
CHO

CH2OH

48•Tutorials CambridgeSoft
Tutorial 4: Fischer Projections
 3. Click Paste to paste the information as a Draw a ring:
caption below the structure.
1. Click the Cyclohexane Ring tool .
CHO
2. Point in an empty area of a document window.
H OH

HO H
3. Click to add a ring.
H OH

H OH

CH2OH

C6H12O6
Exact Mass: 180.06
Mol. Wt.: 180.16
m/e: 180.06 (100.0%), 181.07 (7.1%), 182.07 (1.4%) Rotate the ring:
C, 40.00; H, 6.71; O, 53.29
1. From the Edit menu, choose Select All.
Save and close the document:
1. From the File menu, choose Save.
2. From the File menu, choose Close.

Tutorial 5: Perspective
Drawings 2. Point to the upper right corner of the Selection
Rectangle (the Rotation handle).
In this tutorial you will learn how to create a
perspective drawing by drawing the following
α -D-glucose as a Haworth projection.

CH2OH
O
OH

OH OH
OH NOTE: The cursor changes to a curved double-sided arrow
Create a new document using the ChemDraw to indicate the rotation mode of a selection tool is activated.
default style:
3. Drag the Rotation handle to the right about 30
1. From File menu, point to Open Special, and degrees. The amount of rotation is displayed
then choose New Document. on the screen and in the Info window.
2. From the File menu, choose Save As.
3. Type tut5.cdx in the appropriate text box.
4. Select a folder in which to save the file.
5. Click Save.

ChemDraw 9 Tutorials • 49
Tutorial 5: Perspective Drawings
 Even though Fixed Angles is on, the angle is not 4. Point to C1 again.
constrained. The Fixed Angles feature constrains
O
angles only when they are being drawn. For
example, if you created this ring by dragging instead
Administrator

of clicking, the angle would be constrained when

Fixed Angles is on.
5. Drag downward to create another bond.
Change cyclohexane to tetrahydropyran:
O
1. Click outside the structure to deselect it.
2. Point to the atom indicated below.

6. Repeat for the atoms indicated by the arrows

below.
3. Type o.
O

Add vertical bonds:

The result appears as shown below.
1. Click the Solid Bond tool .
2. Point to the atom shown below. O

3. Drag upward to create a bond. Draw one bond upward at C5:

1. Point to the atom shown below.
O
O

50•Tutorials CambridgeSoft
Tutorial 5: Perspective Drawings
 2. Hold the mouse button and drag upward. Distort the structure to change its aspect ratio to
give the perspective of viewing the structure along
the Z-axis.
1. Click the Lasso tool .
O 2. Point to the Resize handle (lower right corner)
and press the Shift key.

Resize handle
For the downward bond for C5, you must turn
Fixed Lengths off or the bond will be joined to the
upward bond of C3.
You can temporarily disable Fixed Lengths using a NOTE: The cursor changes to a cross with arrows at
modifier key: each end indicating the distortion function of a selection
tool.
1. Point to the atom shown below.
3. Drag upwards until you have distorted the
structure to about 50%, as shown on the screen
O or in the Info window.

2. Hold down the mouse button, press the Alt or

Option key and drag downward from C5. Stop
dragging about half the distance to the upward Next, you create OH labels. Because this label is
bond on C3. repeatedly used, you will learn how to repeat a label.
Only labels created by opening a text box are
repeatable.
O
1. Select the Solid Bond tool, point to the atom
shown below and double-click to open a text
box.

ChemDraw 9 Tutorials • 51
Tutorial 5: Perspective Drawings
 2. Type OH, move the pointer to the next atom as The cursor changes to a bold arrow as you
shown, and triple-click to repeat the atom label. point at the bond.
CH2OH
O
Administrator

O
OH
OH OH OH
OH
3. Triple-click the remaining atoms (as shown 3. Click to change to the new bond type.
below) to repeat the OH label.
CH2OH
O
O OH
OH
OH OH
OH OH OH
OH 4. Click the Bold Wedge bond tool .
NOTE: If you find it difficult to place the labels 5. Point to each of the bonds shown below.
because of the size of the drawing, choose Magnify from CH2OH
the View menu. O
OH

Add the CH2OH label: OH OH

OH
1. Triple-click the upper atom of C5.
2. Press the Enter or Return key to open the
6. For each bond, point slightly off center in the
atom label text box and type CH2 before the
direction that you want the wide end of the
OH.
wedge to be oriented and click.
CH2OH
O
NOTE: If you move the pointer too far, the highlight
OH box disappears. Choose Magnify from the View menu
OH OH
if you find it difficult to place the pointer.
OH
The resulting structure is shown below.
NOTE: The Enter or Return Hotkey opens a text
CH2OH
box for the last atom labeled. The definition for this
O
particular Hotkey cannot be changed. OH

OH OH
Change the type of the front bonds:
OH
1. Click the Bold Bond tool .
NOTE: If the wedge is pointed in the wrong direction,
2. Point to the center of the bond shown below. click the bond again to flip its orientation.

52•Tutorials CambridgeSoft
Tutorial 5: Perspective Drawings
Save and close the document: Tutorial 6: Newman
1. From the File menu, choose Save.
2. From the File menu, choose Close.
Projections
This tutorial demonstrates how to draw a Newman
projection. You can also create the same drawing
using a template.

Create a ChemDraw document:

1. From the File menu, choose New Document.
2. From the File menu, choose Save As.
3. Type tut6.cdx in the appropriate text box.
4. Select a folder in which to save the file.
5. Click Save.

Create the first bond:

1. Click the Solid Bond tool .
2. Point in the document window and drag
downward to create the first bond.

3. Continue pointing at the lower atom and click

again to add a second bond.

ChemDraw 9 Tutorials • 53
Tutorial 6: Newman Projections
 4. Continue pointing at the same atom and click 2. Point to the central atom of the lower
again to add a third bond. fragment.
Administrator

5. Click the Lasso tool .

NOTE: When connecting existing atoms, the Fixed
The last structure you drew is automatically Length and Fixed Angles commands are ignored.
selected.
6. Point within the Selection rectangle and hold 3. Click and drag to the central atom of the upper
the Ctrl or Option key. fragment.
4. Release the mouse button when the highlight
box over the central atom appears.

7. Hold the mouse button and drag a copy of the

structure diagonally upward to the right of the
original.

In this step, you will use the Orbital tool to draw the
hollow circle that is particular to Newman
Projections rather than an orbital.
1. Click the Orbital tool .
2. Click the unfilled s orbital.

8. Release the mouse button and depressed key

when the copy is positioned.
Add a bond between the duplicated structures:
1. Click the Solid Bond tool . 3. Point to the left center carbon and drag
outward.

54•Tutorials CambridgeSoft
Tutorial 6: Newman Projections
 The size of the orbital is constrained just like Rotate the selection:
bonds. The constraint is based on a percentage
1. Double-click the Rotation handle in the upper
of the Fixed Length setting in the Drawing
right of the Selection Rectangle to open the
Settings dialog box.
Rotate dialog box.

NOTE: Orbitals are not automatically grouped with 2. Type 180 in the text box, select degrees CW,
the closest structure. If you want to group the orbital and then click Rotate.
with the existing structure so you can move them as a
unit, choose Group from the Object menu.

Move part of the structure to the front to overlap

the orbital: RotateObjectsDB 150 dpi

1. Click the Marquee tool . Change the layering of the structure so that the
2. Point above the structure and drag around the selection is in front:
upper fragment to select the three bonds. • From the Object menu, choose Bring to
Front.

Orient the front part of the structure to create a

Newman projection.
1. Point within the Selection Rectangle until the
pointer changes to a hand.

NOTE: Only bonds that are completely within the Lasso

area are selected. Do not select the bond connecting the two
fragments. Alternately, you can Shift+click on each bond
separately.

ChemDraw 9 Tutorials • 55
Tutorial 6: Newman Projections
 2. Drag the selection until the central atom of the 1. Click the Solid Bond tool .
selection is centered within the orbital. 2. Click in the document window and drag
downward to create the first bond.
Administrator

3. Continue pointing at the lower atom and click

3. Release the mouse button and click outside the again to add a second bond.
Selection Rectangle to deselect the structure.
Save and close the document:
1. From the File menu, choose Save.
2. From the File menu, choose Close.
4. Continue pointing at the same atom and click
Tutorial 7: Showing again to add a third bond.

Stereochemistry
This tutorial demonstrates using Stereochemistry
markers and the flip command.
5. Point to the atom shown below and click.
Create a new document.
1. From the File menu, choose New Document.
2. From the File menu, choose Save As.
3. Type tut7.cdx in the appropriate text box.
4. Select a folder in which to save the file. 6. Point to the atom shown below and click twice
to create two bonds.
5. Click Save.
Draw the following structure:
O

7. Pointing to the bond shown below, right-click,

OH point to Double, and then choose Plain.
NH2

56•Tutorials CambridgeSoft
Tutorial 7: Showing Stereochemistry
 8. Click the Wedged Bond tool, point to the atom Display the stereochemical markers.
below, and then click.
1. Select the entire structure with the Lasso or
Marquee.
2. From the Object menu, choose Show
Stereochemistry.
The S marker appears.
Add atom labels.
O
1. With the Text tool, click the atom shown
below, and then type NH2 in the text box that
appears. (S)
OH

NH2
3. Select the structure and from the Object menu,
choose Flip Horizontal.
The R marker appears.
O
2. With the Text tool, click the atom shown
below, and then type O in the text box that
appears. (R)
HO

NH2
4. With the structure selected do the following:
Click the Object menu. While holding the
mouse button, press the Alt or Shift+Option
NH2 key and choose Rotate 180° Vertical.
3. With the Text tool, click the atom shown
below, and then type OH in the text box that NH2
appears.
HO
O (R)

O
The Wedged bond becomes hashed and the (R)
stereochemistry is preserved.
NH2
Save and close the document:
1. From the File menu, choose Save.
2. From the File menu, choose Close.

ChemDraw 9 Tutorials • 57
Tutorial 7: Showing Stereochemistry
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58•Tutorials CambridgeSoft
Tutorial 7: Showing Stereochemistry