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Drug Study - Clarithromycin

1. The document summarizes a drug study on clarithromycin, a macrolide antibiotic commonly used to treat respiratory tract, skin, and soft tissue infections. 2. Clarithromycin is typically administered orally twice daily and works by binding to bacterial ribosomes and blocking protein synthesis. 3. Common adverse effects include diarrhea, nausea, vomiting, and abdominal pain. Nurses are responsible for monitoring patients, educating them on potential side effects, and ensuring adequate hydration.

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Trisha Lapid Matula
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1K views2 pages

Drug Study - Clarithromycin

1. The document summarizes a drug study on clarithromycin, a macrolide antibiotic commonly used to treat respiratory tract, skin, and soft tissue infections. 2. Clarithromycin is typically administered orally twice daily and works by binding to bacterial ribosomes and blocking protein synthesis. 3. Common adverse effects include diarrhea, nausea, vomiting, and abdominal pain. Nurses are responsible for monitoring patients, educating them on potential side effects, and ensuring adequate hydration.

Uploaded by

Trisha Lapid Matula
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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University of St.

La Salle
College of Nursing

DRUG STUDY

Name of Student: ______________________________________Section


Trisha L. Matula BSN-3G
and Group: ________________________
Name of CI: ___________________________________________
Hanna B. Gella Area of Exposure: _________________________
Dosage/Frequency/Timing/ Nursing
Name of Drug Mechanism of Action Indication Contraindication Adverse Effect
Route Responsibilities

Generic Name: Clarithromycin is first Intravenous Contraindicated 1. Maintain


500 mg PO BID
Clarithromycin metabolized to 14-OH Respiratory to patients who  Diarrhea adequate
clarithromycin, which tract have known  Nausea hydration.
is active and works infections, hypersensitivity 2. Advise
 Vomiting
synergistically with its Skin and to macrolides patient
soft tissue  Stomach
parent compound. antibiotics. pain about the
infections
Like other macrolides, Contraindicated likelihood
 Heartburn
Brand Name: it then penetrates to certain heart of GI
.
Biaxin bacteria cell wall and problems Qt reactions,
 Gas.
reversibly binds to prolongation. including
domain V of the 23S Contraindicated  Change in nausea,
taste.
ribosomal RNA of the to patient who diarrhea,
50S subunit of the have electrolyte  Headache. indigestion,
bacterial ribosome, imbalance (e.g abnormal
Classification: blocking translocation low potassium or taste, and
macrolide of aminoacyl transfer- sodium level) abdominal
antibiotics RNA and polypeptide pain.
synthesis. 3. Instruct
Clarithromycin also patient to
inhibits the hepatic report
microsomal CYP3A4 severe or
isoenzyme and P- prolonged
glycoprotein, an GI
energy-dependent problems.
drug efflux pump. 4. Monitor
and record
vital signs.

Reference:

 MIMS, clarithromycin, Retrieved August 15, 2022 at https://www.mims.com/philippines/drug/info/clarithromycin?mtype=generic


 Drug bank online, clarithromycin, Retrieved August 15, 2022 at https://go.drugbank.com/drugs/DB01211
 Scribd, Clarithromycin Drug Study, Retrieved august 15, 2022 https://www.scribd.com/doc/184102754/clarithromycin-drug-study

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