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Drug Study Ranitidine

1) Zantac (ranitidine) is an antisecretory drug that competitively and reversibly inhibits histamine action at H2-receptor sites on parietal cells, thus blocking gastric acid secretion. 2) It is used for the short-term treatment of active duodenal ulcer, maintenance therapy for duodenal ulcer patients after healing of acute ulcer, treatment of gastroesophageal reflux disease, short-term treatment of active, benign gastric ulcer, and treatment of pathologic GI hypersecretory conditions. 3) Potential adverse effects include headache, malaise, dizziness, somnolence, insomnia, vertigo, mental confusion, agitation, depression

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Tipey Segismundo
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510 views2 pages

Drug Study Ranitidine

1) Zantac (ranitidine) is an antisecretory drug that competitively and reversibly inhibits histamine action at H2-receptor sites on parietal cells, thus blocking gastric acid secretion. 2) It is used for the short-term treatment of active duodenal ulcer, maintenance therapy for duodenal ulcer patients after healing of acute ulcer, treatment of gastroesophageal reflux disease, short-term treatment of active, benign gastric ulcer, and treatment of pathologic GI hypersecretory conditions. 3) Potential adverse effects include headache, malaise, dizziness, somnolence, insomnia, vertigo, mental confusion, agitation, depression

Uploaded by

Tipey Segismundo
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Dose,

Name and Frequency,


Mechanism
Classification of Route, Duration Indication Contraindication Adverse Effects Nursing Responsibility
of Action
Drug of
Administration
Brand Name: Dose: Potent anti- Short-term Hypersensitivity CNS: Headache, Potential toxicity results
Zantac 50mg ulcer treatment of to malaise, dizziness, from decreased clearance
drug that active duodenal ranitidine; acute somnolence, (elimination) and therefore
Generic Name: Frequency: competitively ulcer. porphyria; OTC insomnia, vertigo, prolonged action; greatest
Ranitidine q8 and Maintenance administration in mental confusion, in the older adult patients
reversibly therapy for children agitation, or those with hepatic or
Drug Class: Route: inhibits duodenal ulcer <12 y. depression, renal dysfunction.
Antisecretory IV histamine patient after hallucinations in
action healing of acute older adults.
at H2- ulcer; treatment CV:
receptor of Bradycardia (with
sites on gastroesophagea rapid IV push).
parietal l reflux disease; GI: Constipation,
cells, thus short-term nausea, abdominal
blocking treatment of pain, diarrhea.
gastric active, benign Skin: Rash.
acid gastric ulcer; Hematologic:
secretion. treatment of Reversible
Indirectly pathologic GI decrease in WBC
reduces hypersecretory count,
pepsin conditions (e.g., thrombocytopenia.
secretion Zollinger- Body as a Whole:
but appears Ellison Hypersensitivity
to syndrome, reactions,
have minimal systemic anaphylaxis (rare).
effect on mastocytosis,
fasting and
and postoperative
postprandial hypersecretion);
serum gastrin heartburn.
concentration
s or
secretion of
gastric
intrinsic
factor or
mucus

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