JHEVILINE D.

LEOPANDO
Science Teacher
+639209796252 / [email protected]

LEARNING ACTIVITY # 11
NAME:_________________________________________________ GRADE / SCORE:____________
YEAR AND SECTION:GRADE 10 COMPASSION/COMMITMENT __ DATE: FEBRUARY 1-5, 2021
SUBJECT: SCIENCE 10 __  Grade School  JHS  SHS

PLEASE SHADE THE APPROPRIATE TYPE OF ACTIVITY:

 Concept Notes  Laboratory Report  Formal Theme  Practical Activity
 Skill Demonstration /  Drawing / Art  Informal Theme  Others:
Exercise / Drill ___________________

ACTIVITY TITLE: SAY IT WITH DNA (A Review from your Grade 9)

LEARNING TARGETS: a. to identify the amino acid that is coded by a given DNA sequence
REFERENCE(S) Experiments in Science, Aquiman, Jessarie A. pp. 50-52
(Title, Author, Pages)
CONCEPT NOTES:
DNA (deoxyribonucleic Acid), is a molecular structure that contains the genetic code of organisms.
 This is composed of units called NUCLEOTIDES which are composed of sub-molecules;
(a) Pentose sugar (deoxyribose), Phosphate, Nitrogenous base.

In the middle of the molecule there are pairs of bases. There are four possible bases in DNA –
Adenine, Thymine, Cytosine and Guanine – but they are often represented by their letters A,T,C and G.

Bases pair up in a totally predictable way across the double stranded DNA molecule:

A always pairs with T, C always pairs with G. Why is this? Well you can see from the diagram above
that A and T are held together by two weak bonds called Hydrogen (H) bonds, whereas C and G are
held together by 3 H bonds. This means that this is the only way they can pair up in a stable way.

These pairs of bases (A=T and C≡G) are called complementary base pairs because they
always match up in a predictable way.

You can also get complementary base pairing between RNA bases. (Remember that in RNA,
there is never any thymine but it is replaced with a different base called uracil) So A=U and C≡G are
the complementary base pairs between two RNA molecules.

Complementary base pairing between DNA and RNA bases is essential in transcription but you
do not need to know the details at this stage.

KINDLY WATCH THIS LINK FOR MORE INFORMATION FOR DNA REPLICATION:
http://www.youtube.com/watch?v=6gUY5NoX1Lk
https://youtu.be/hC_8y8fNkCw
Protein Synthesis on Vimeo
 JHEVILINE D. LEOPANDO
Science Teacher
+639209796252 / [email protected]

Amino Acids Found in Human DNA. Each of these has one or more genetic codon which is present
within the molecule of specific messenger RNA, ribonucleic Acid which themselves is produced under
the direction of a gene occurring in DNA molecules.

ACTIVITY 1 – SAY IT WITH DNA: Protein Synthesis

DICTIONARY

tRN
tRNA AA Letter tRNA AA Letter tRNA AA Letter AA Letter
A
AAA Phe F CAA Val V GAA Leu L UAA Iso I
AAC Leu L CAC Val V GAC Leu L UAC Met M
AAG Phe F CAG Val V GAG Leu L UAG Iso I
AAU Leu L CAU Val V GAU Leu L UAU Iso I
ACA Cys C CCA Gly G GCA Arg R UCA Ser S
ACC Trp W CCC Gly G GCC Arg R UCC Arg R
ACG Cys C CCG Gly G GCG Arg R UCG Ser S
ACU The O CCU Gly G GCU Arg R UCU Arg R
AGA Ser S CGA Ala A GGA Pro P UGA Thr T
AGC Ser S CGC Ala A GGC Pro P UGC Thr T
AGG Ser S CGG Ala A GGG Pro P UGG Thr T
AGU Ser S CGU Ala A GGU Pro P UGU Thr T
AUA Tyr Y CUA Asp D GUA His H UUA Asn N
AUC Spc - CUC Glu E GUC Glu Q UUC Lys K
AUG Tyr Y CUG Asp D GUG His H UUG Asn N
AUU Spc - CUU Glu E GUU Glu Q UUU Lys K

NOTE: AA = Amino Acid; Spc = “space”

 JHEVILINE D. LEOPANDO
Science Teacher
+639209796252 / [email protected]

Example:

1. DNA CTA TTA CGA ATC TAG AGC ATT GAA TAG AAA CTT
mRNA GAU AAU GCU UAG AUC UCG UAA CUU AUC UUU GAA
tRNA CUA UUA CGA AUC UAG AGC AUU GAA UAG AAA CUU
AA Asp Asn Ala Spc Iso Ser Spc Leu Iso Phe Glu
Letter D N A - I S - L I F E
CODE DNA IS LIFE

Codes: C - G
G - C
A - U
T - A
U - A

Try to Answer:

1. DNA TAC ATA ATC GTA CGC GGG GGC ATG ATT ACG CGA TGA
mRNA
tRNA
AA
Letter
CODE

2. DNA TGC GTA CTC ATC ACG ACU ACC ATT TAA TCG ATT GGG TAT TTA TTC

mRNA

tRNA

AA

Letter

CODE

3. DNA AGT TGC GCC CTT CTC TGC ATT TAC CGC AGA TGC CTT GCC
mRNA
tRNA
AA
Letter
CODE
(Title, Author, Pages)
 JHEVILINE D. LEOPANDO
Science Teacher
+639209796252 / [email protected]
LEARNING ACTIVITY # 12
NAME:_________________________________________________ GRADE / SCORE:____________
YEAR AND SECTION:GRADE 10 COMPASSION/COMMITMENT __ DATE: FEBRUARY 1-5, 2021
SUBJECT: SCIENCE 10 __  Grade School  JHS  SHS

PLEASE SHADE THE APPROPRIATE TYPE OF ACTIVITY:

 Concept Notes  Laboratory Report  Formal Theme  Practical Activity
 Skill Demonstration /  Drawing / Art  Informal Theme  Others:
Exercise / Drill ___________________

ACTIVITY TITLE: GENE MUTATIONS

LEARNING TARGETS: a. explain how mutations may cause changes in the structure and
function of the protien
REFERENCE(S) Exploring Life Through Science, Sta. Ana, Susan T. S., pp. 153-158
(Title, Author, Pages)

CONCEPT NOTES
Genes are segments of DNA located in the chromosomes.
Gene mutation is defined as alteration in the sequence of nucleotide in DNA.
Two types:
1. Hereditary mutation – inherited from parents and present throughout a person’s life in
almost every cell in the body.
2. Acquired mutations – occurred at some time in a person’s life, present only in some
cells acquired throughout environmental factors like exposure to
ultraviolet rays.
Gene mutations cause changes in the genetic code leading to genetic variation and the probability of
developing disease.

ACTIVITY 1: Define the following genetic disorders.

1. Sickel cell anemia

2. Cystic fibrosis
3. Tay-Sachs disease
4. Huntingtons disease
5. Hemophilia

ACTIVITY 2: Research time! Have a research about the different genetic disorder listed below.
Describe, print and paste a photo of each.

GENETIC DISORDER DESCRIPTION

Photo here Progeriac Syndrome

Photo here Deletion Syndrome

 JHEVILINE D. LEOPANDO
Science Teacher
+639209796252 / [email protected]

Photo here Cri-du-chat Syndrome

Photo here Turner Syndrome

Photo here Down Syndrome

Photo here Edward Syndrome

Photo here Jacob Syndrome

Photo here Albinism