DRUG STUDY:

Generic Brand Dosage Mechanism Indication Contra- Adverse Reaction Nursing

Name name Indication Responsibility
Clopidogrel Plavix 75mg Clopidogrel Prevention of Hypersensitivity Gastrointestinal -Assess patient
every selectively atherothromb to clopidogrel or System Disorders: for symptoms of
other inhibits the otic events any component Common: stroke,
day OD binding of in: Patients of Plavix. peripheral
Diarrhea,
12mn adenosine suffering vascular disease,
diphosphate from Severe liver abdominal pain,
or MI
(ADP) to its myocardial impairment. dyspepsia. periodically
platelet infarction Uncommon: during therapy.
receptor, (from a few Active Gastric ulcer and
thereby days until pathological duodenal ulcer, -Monitor bleeding
inhibiting <35 days), bleeding eg, gastritis, vomiting, time during
platelet ischemic peptic ulcer or therapy.
nausea,
aggregation. stroke (from intracranial
7 days until hemorrhage. constipation,
-Monitor CBC with
<6 months) flatulence.
differential and
or Breastfeeding
CNS and PNS platelet count
established
peripheral Disorders: periodically during
arterial Uncommon: therapy
disease. Headache,
dizziness and
paresthesia. Rare:
Vertigo.
Generic Brand Dosage Mechanism Indication Contra- Adverse Reaction Nursing
Name name Indication Responsibility
Bambuterol Bambec 10mg attributable to Bronchial Hypersensitivity Headache, - Caution patient
HCl OD 6pm stimulation asthma, to terbutaline. palpitations, not totake any
through beta- chronic restlessness, prescriptionand
adrenergic bronchitis, urticaria, OTC drugs
receptors of emphysema exanthema, unlessprescribed
intracellular & other lung tremor, cramps in by the physician
adenyl cyclase, diseases hands & feet.
the enzyme that where - Instruct Patient if
catalyzes the bronchospas hypersensitivity
conversion of m is a reaction occurs
adenosine complicating during the
triphosphate factor. medication,immediat
(ATP) to cyclic ely notify
AMP. Increased thephysician.
cyclic AMP
levels are
associated with
relaxation of
bronchial
smooth muscle
and inhibition of
release of
mediators of
immediate
hypersensitivity
from cells
Generic Brand Dosage Mechanism Indication Contra- Adverse Reaction Nursing
Name name Indication Responsibility
Montelukast Brecare 10mg attributable to Bronchial Hypersensitivity Headache,
Na OD 6pm stimulation asthma, to terbutaline. palpitations,
through beta- chronic restlessness,
adrenergic bronchitis, urticaria,
receptors of emphysema exanthema,
intracellular & other lung tremor, cramps in
adenyl cyclase, diseases hands & feet.
the enzyme that where
catalyzes the bronchospas
conversion of m is a
adenosine complicating
triphosphate factor.
(ATP) to cyclic
AMP. Increased
cyclic AMP
levels are
associated with
relaxation of
bronchial
smooth muscle
and inhibition of
release of
mediators of
immediate
hypersensitivity
from cells
Generic Brand Dosage Mechanism Indication Contra- Adverse Reaction Nursing
Name name Indication Responsibility
Telmisartan Micardis 40mg Telmisartan Treatment of Pregnancy & Headache, upper - special
OD 8am blocks the essential lactation, biliary resp tract precaution in
vasoconstrictor HTN. obstructive infection, patients with
and aldosterone Prevention of disorders, dizziness, fatigue. impaired hepatic
secreting CV morbidity severe hepatic and
effects of and mortality impairment. renal impairment
angiotensin II in patients
by selectively ≥55 yr at - special
blocking the high risk of precaution
binding of CV disease. with volume
angiotensin II to and/or
the AT1 Na-depleted
receptor in patients
many tissues,
such as - may impair
vascular ability to drive or
smooth muscle operate
and the adrenal machineries
gland. Its action
is therefore
independent of
the pathways
for angiotensin
II synthesis.
Generic Brand Dosage Mechanism Indication Contra- Adverse Reaction Nursing
Name name Indication Responsibility
Glipizide Brilizid 5mg ½ Glipizide is an Treatment of IDDM, Nausea, • Assess patients
tab OD oral drug that is type 2 ketoacidosis vomiting, glucose level before
6am used for treating diabetes diabetes, heartburn, therapy and regularly
patients with mellitus. diabetic anorexia, thereafter to monitor
type 2 diabetes. precoma or diarrhea, the drug’s
It belongs to the coma, severely metallic taste, effectiveness.
sulfonylurea impaired kidney increased
class of drugs or liver function, appetite, wt • Be alert for the
that includes adrenal gain, skin rash adverse reactions of
glimepiride insufficiency. & pruritus. the drug.
(Amaryl), Latent diabetes
glyburide or prediabetic • Assess patient’s and
(Micronase, states. family’s knowledge
Diabeta), Pregnancy. of
tolbutamide drug therapy.
(Orinase) and
tolazamide
(Tolinase).
Generic Brand Dosage Mechanism Indication Contra- Adverse Reaction Nursing
Name name Indication Responsibility
Adenosine Adepos 1 drop Adenosine is Treatment Second or third Lightheadedness,
Triphosphate on both primarily formed of various degree AV hypotension,
eyes 3x from the type of block, or sick paresthesia,
daily breakdown product cataract. sinus syndrome shortness of
of adenosine breath, headache,
triphosphate (ATP). Hypersensitivity transient periods
Both compounds to adenosine of sinus
are found in every bradycardia and
cell of the human ventricular
body, and have a ectopy,
wide range of palpitations, chest
metabolic roles. Its pain, nauseua
actions in the AV
node are thought to
act through
stimulation of
specific adenosine
receptors.
Adenosine slows
those tachycardias
associated with the
AV node (i.e. AV
Node Re-entry
Tachycardias) by
decreasing
conductivity
through the node.